targetscan.Mm.egTARGETSFULL {targetscan.Mm.eg.db} | R Documentation |
targetscan.Mm.egTARGETSFULL maps Entrez gene idenifiers to miRNA families. The mappings are taken from the TargetScan database.
TargetScan predicts biological targets of miRNAs by searching for a presence of conserved 8mer and 7mer sites that match the seed region of each miRNA.
There are currently two annotation packages for TargetScan, one for human and another one for mouse. These correspond to the TargetScanHuman and the TargetScanMouse databases, see the TargetScan website for details.
targetscan.Mm.egTARGETSFULL is an R object containing key and value pairs. Keys are Entrez gene identifiers and values are lists, each list member corresponds to a predicted targeting miRNA family. Each list member is itself a list with the following members:
Friedman RC, Farh KK, Burge CB, Bartel DP.: Most mammalian mRNAs are conserved targets of microRNAs. Genome Res. 2009 Jan;19(1):92-105
http://www.targetscan.org for TargetScan and http://microrna.sanger.ac.uk/sequences/ for miRBase.
targetscan.Mm.egTARGETSFULL for more information about the miRNA targets.
## Get the miRNA families that regulate these genes genes <- sample(ls(targetscan.Mm.egTARGETSFULL), 3) mget(genes, targetscan.Mm.egTARGETSFULL)