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CIG Publications

2009

 

 
    Yang, J. Y., Walicki, J., Jaccard, E., Dubuis, G., Bulat, N., Hornung, J. P., Thorens, B., Widmann, C.: Expression of the N-terminal fragment of RasGAP in pancreatic beta cells increases their resistance to stresses and protects mice from diabetes. Diabetes 2009, 58:2596-606. URL

    Witz, G., Stasiak, A.: DNA supercoiling and its role in DNA decatenation and unknotting. Nucleic Acids Res 2009,
    URL

    Wahli, W., Constantin, N.: La nutrigénomique, un défi médico-socio-économique. Swiss Medical Forum 2009, 9:242-245. URL

    Tyagi, S., Herr, W.: E2F1 mediates DNA damage and apoptosis through HCF-1 and the MLL family of histone methyltransferases. Embo J 2009, 28:3185-95. URL

    Tsai, J. W., Hannibal, J., Hagiwara, G., Colas, D., Ruppert, E., Ruby, N. F., Heller, H. C., Bourgin, P., Franken, P.: Melanopsin as a sleep modulator: circadian gating of the direct effects of light on sleep and altered sleep homeostasis in Opn4(-/-) mice. PLoS Biol 2009, 7:e1000125. URL

    Thorens, B., Mueckler, M. M.: Glucose transporters in the 21st Century. Am J Physiol Endocrinol Metab 2009,
    URL

    Tafti, M.: Genetic aspects of normal and disturbed sleep. Sleep Med 2009, 10 Suppl 1:S17-21. URL

    Stephenson, P. G., Fankhauser, C., Terry, M. J.: PIF3 is a repressor of chloroplast development. Proc Natl Acad Sci U S A 2009, 106:7654-9. URL

    Silva, J. P., von Meyenn, F., Howell, J., Thorens, B., Wolfrum, C., Stoffel, M.: Regulation of adaptive behaviour during fasting by hypothalamic Foxa2. Nature 2009, 462:646-50. URL

    Sanderson, L. M., Degenhardt, T., Koppen, A., Kalkhoven, E., Desvergne, B., Muller, M., Kersten, S.: PPAR{beta}/{delta} but not PPAR{alpha} serves as plasma free fatty acid sensor in liver. Mol Cell Biol 2009, 29:6257-67. URL

    Rotman, N., Wahli, W.: Fatty acid synthesis and PPARalpha hand in hand. Chem Biol 2009, 16:801-2. URL

    Roques, C., Coulombe, Y., Delannoy, M., Vignard, J., Grossi, S., Brodeur, I., Rodrigue, A., Gautier, J., Stasiak, A. Z., Stasiak, A., Constantinou, A., Masson, J. Y.: MRE11-RAD50-NBS1 is a critical regulator of FANCD2 stability and function during DNA double-strand break repair. Embo J 2009, 28:2400-13. URL

    Rawdon, E.J., Kern, J., Piatek, M., Stasiak, A., Millet, K.C.: Shapes of knotted cyclic polymers. Proceedings of the conference: Knots and soft-matter physics 2009,
    32-37.

    Preitner, F., Bonny, O., Laverriere, A., Rotman, S., Firsov, D., Da Costa, A., Metref, S., Thorens, B.: Glut9 is a major regulator of urate homeostasis and its genetic inactivation induces hyperuricosuria and urate nephropathy. Proc Natl Acad Sci U S A 2009, 8:36. URL

    Potrzebowski, L., Vinckenbosch, N., Kaessmann, H.: The emergence of new genes on the young therian X. Trends Genet 2009,
    URL

    Plasari, G., Calabrese, A., Dusserre, Y., Gronostajski, R. M., McNair, A., Michalik, L., Mermod, N.: Nuclear Factor I-C links PDGF and TGF-{beta}1 signaling to skin wound healing progression. Mol Cell Biol 2009, 29:6006-17. URL

    Petremand, J., Bulat, N., Butty, A. C., Poussin, C., Rutti, S., Au, K., Ghosh, S., Mooser, V., Thorens, B., Yang, J. Y., Widmann, C., Waeber, G.: Involvement of 4E-BP1 in the protection induced by HDLs on pancreatic beta cells. Mol Endocrinol 2009, 23:1572-86. URL

    Millett, K. C., Plunkett, P., Piatek, M., Rawdon, E. J., Stasiak, A.: Effect of knotting on polymer shapes and their enveloping ellipsoids. J Chem Phys 2009, 130:165104. URL

    Millett, K. C., Plunkett, P., Piatek, M., Rawdon, E. J., Stasiak, A.: Shapes of knotted cyclic polymers. 2009,


    Martinez-Robles, M. L., Witz, G., Hernandez, P., Schvartzman, J. B., Stasiak, A., Krimer, D. B.: Interplay of DNA supercoiling and catenation during the segregation of sister duplexes. Nucleic Acids Res 2009, 37:4887-4897. URL

    Marenduzzo, D.*, Orlandini, E., Stasiak, A.*, Sumners, D. W., Tubiana, L., Micheletti, C., *co-first authors,: DNA-DNA interactions in bacteriophage capsids are responsible for the observed DNA knotting. Proc Natl Acad Sci U S A 2009,
    URL

    Makrythanasis, P., Kapranov, P., Bartoloni, L., Reymond, A., Deutsch, S., Guigo, R., Denoeud, F., Drenkow, J., Rossier, C., Ariani, F., Capra, V., Excoffier, L., Renieri, A., Gingeras, T. R., Antonarakis, S. E.: Variation in Novel Exons (RACEfrags) of the MECP2 Gene in Rett Syndrome Patients and Controls. Hum Mutat 2009, 30:E866-79. URL

    Lorrain, S., Trevisan, M., Pradervand, S., Fankhauser, C.: Phytochrome Interacting Factors 4 and 5 redundantly limit seedling de-etiolation in continuous far-red light. Plant J 2009, 60:449-461. URL

    Lohmann, C., Schafer, N., von Lukowicz, T., Sokrates Stein, M. A., Boren, J., Rutti, S., Wahli, W., Donath, M. Y., Luscher, T. F., Matter, C. M.: Atherosclerotic mice exhibit systemic inflammation in periadventitial and visceral adipose tissue, liver, and pancreatic islets. Atherosclerosis 2009, 207:360-7. URL

    Leuenberger, N., Pradervand, S., Wahli, W.: Sumoylated PPARalpha mediates sex-specific gene repression and protects the liver from estrogen-induced toxicity in mice. J Clin Invest 2009, 119:3138-48. URL

    Le Martelot, G., Claudel, T., Gatfield, D., Schaad, O., Kornmann, B., Sasso, G. L., Moschetta, A., Schibler, U.: REV-ERBalpha participates in circadian SREBP signaling and bile acid homeostasis. PLoS Biol 2009, 7:e1000181. URL

    Kaessmann, H., Vinckenbosch, N., Long, M.: RNA-based gene duplication: mechanistic and evolutionary insights. Nat Rev Genet 2009, 10:19-31. URL

    Kaessmann, H.: Genetics. More than just a copy. Science 2009, 325:958-9. URL

    Isken, F., Weickert, M. O., Tschop, M. H., Nogueiras, R., Mohlig, M., Abdelrahman, A., Klaus, S., Thorens, B., Pfeiffer, A. F.: Metabolic effects of diets differing in glycaemic index depend on age and endogenous glucose-dependent insulinotrophic polypeptide in mice. Diabetologia 2009, 52:2159-68. URL

    Hornitschek, P., Lorrain, S., Zoete, V., Michielin, O., Fankhauser, C.: Inhibition of the shade avoidance response by formation of non-DNA binding bHLH heterodimers. Embo J 2009, 28:3893-902. URL

    Hor, H., Tafti, M.: Physiology. How much sleep do we need?. Science 2009, 325:825-6. URL

    Henrichsen*, C. N., Vinckenbosch*, N., Zollner, S., Chaignat, E., Pradervand, S., Schutz, F., Ruedi, M., Kaessmann, H., Reymond, A.: Segmental copy number variation shapes tissue transcriptomes. Nat Genet 2009,
    URL

    Henrichsen, C. N., Chaignat, E., Reymond, A.: Copy number variants, diseases and gene expression. Hum Mol Genet 2009, 18:R1-8. URL

    Hasan, S., Pradervand, S., Ahnaou, A., Drinkenburg, W., Tafti, M., Franken, P.: How to keep the brain awake? The complex molecular pharmacogenetics of wake promotion. Neuropsychopharmacology 2009, 34:1625-40. URL

    Harrow, J., Nagy, A., Reymond, A., Alioto, T., Patthy, L., Antonarakis, S. E., Guigo, R.: Identifying protein-coding genes in genomic sequences. Genome Biol 2009, 10:201. URL

    Gregory, A.M., Franken, P.: Genetic approaches to the problem of sleep In Current Advances in Sleep Biology Edited by Frank, M.G:; New York: Nova Science Publishers; 2009: 41-61.

    Gatfield, D., Le Martelot, G., Vejnar, C. E., Gerlach, D., Schaad, O., Fleury-Olela, F., Ruskeepaa, A. L., Oresic, M., Esau, C. C., Zdobnov, E. M., Schibler, U.: Integration of microRNA miR-122 in hepatic circadian gene expression. Genes Dev 2009, 23:1313-26. URL

    Franken*, P., Langmesser*, S., Feil, S., Emmenegger, Y., Albrecht, U., Feil, R.: cGMP-dependent protein kinase type I is implicated in the regulation of the timing and quality of sleep and wakefulness. PLoS ONE 2009, 4:e4238. URL

    Franken, P., Kopp, C., Landolt, H. P., Luthi, A.: The functions of sleep. Eur J Neurosci 2009, 29:1739-40. URL

    Franken, P., Dijk, D. J.: Circadian clock genes and sleep homeostasis. Eur J Neurosci 2009, 29:1820-9. URL

    Franken, P.: Understanding sleep through genetic analysis. Front Neurosci 2009, 3:416-7.

    Fablet, M., Bueno, M., Potrzebowski, L., Kaessmann, H.: Evolutionary origin and functions of retrogene introns. Mol Biol Evol 2009, 26:2147-56. URL

    Dorier, J., Stasiak, A.: Topological origins of chromosomal territories . Nucleic Acids Res 2009, 37:6316-6322. URL

    Dorier, J., Burnier, Y., stasiak, A.: Inhibitory effect of DNA supercoiling on DNA knotting. Proceedings of the conference: Knots and soft-matter physics 2009,
    84-88.

    Diao, Y., Ernst, C., Stasiak, A.: A partial ordering of knots through diagramatic unknotting. Journal of Knot Theory and Its Ramifications 2009, 18:505-22. URL

    Desvergne, B., Heligon, C.: Steroid hormone pulsing drives cyclic gene expression. Nat Cell Biol 2009, 11:1051-3. URL

    Desvergne, B., Feige, J. N., Casals-Casas, C.: PPAR-mediated activity of phthalates: A link to the obesity epidemic?. Mol Cell Endocrinol 2009, 304:43-8. URL

    Demurtas, D., Amzallag, A., Rawdon, E. J., Maddocks, J. H., Dubochet, J., Stasiak, A.: Bending modes of DNA directly addressed by cryo-electron microscopy of DNA minicircles. Nucleic Acids Res 2009, 37:2882-93. URL

    Demers, A., Caron, V., Rodrigue-Way, A., Wahli, W., Ong, H., Tremblay, A.: A concerted kinase interplay identifies PPARgamma as a molecular target of ghrelin signaling in macrophages. PLoS One 2009, 4:e7728. URL

    Demarsy, E., Fankhauser, C.: Higher plants use LOV to perceive blue light. Curr Opin Plant Biol 2009, 12:69-74. URL

    Dauvilliers, Y., Abril, B., Mas, E., Michel, F., Tafti, M.: Normalization of hypocretin-1 in narcolepsy after intravenous immunoglobulin treatment. Neurology 2009, 73:1333-4. URL

    Cornu, M., Yang, J. Y., Jaccard, E., Poussin, C., Widmann, C., Thorens, B.: Glucagon-like peptide-1 protects beta-cells against apoptosis by increasing the activity of an IGF-2/IGF-1 receptor autocrine loop. Diabetes 2009, 58:1816-25. URL

    Cornu, M., Thorens, B.: GLP-1 protects beta-cells against apoptosis by enhancing the activity of an IGF-2/IGF-1 receptor autocrine loop. Islets 2009, 1:280-282.

    Chong*, H. C., Tan*, M. J., Philippe, V., Tan, S. H., Tan, C. K., Ku, C. W., Goh, Y. Y., Wahli, W., Michalik, L., Tan, N. S.: Regulation of epithelial-mesenchymal IL-1 signaling by PPARbeta/delta is essential for skin homeostasis and wound healing. J Cell Biol 2009, 184:817-31. URL

    Buhren, B. A., Gasis, M., Thorens, B., Muller, H. W., Bosse, F.: Glucose-dependent insulinotropic polypeptide (GIP) and its receptor (GIPR): cellular localization, lesion-affected expression, and impaired regenerative axonal growth. J Neurosci Res 2009, 87:1858-70. URL

    Bovine_Genome_Sequencing_and_Analysis_Consortium, authors_from_the_CIG:, Reymond, A., Chrast, J., Henrichsen, C. N.: The genome sequence of taurine cattle: a window to ruminant biology and evolution. Science 2009, 324:522-8. URL

    Bibert, S., Kharoubi Hess, S., Firsov, D., Thorens, B., Geering, K., Horisberger, J. D., Bonny, O.: Mouse GLUT9: evidences for a urate uniporter. Am J Physiol Renal Physiol 2009,
    URL

    Benton, R., Vannice, K. S., Gomez-Diaz, C., Vosshall, L. B.: Variant ionotropic glutamate receptors as chemosensory receptors in Drosophila. Cell 2009, 136:149-62. URL

    Benton, R.: Molecular basis of odor detection in insects. Ann N Y Acad Sci 2009, 1170:478-81. URL

    Benton, R.: Eppendorf winner. Evolution and revolution in odor detection. Science 2009, 326:382-3. URL

    Ali, F. Y., Hall, M. G., Desvergne, B., Warner, T. D., Mitchell, J. A.: PPAR{beta}/{delta} Agonists Modulate Platelet Function via a Mechanism Involving PPAR Receptors and Specific Association/Repression of PKC{alpha}. Arterioscler Thromb Vasc Biol 2009, 29:1871-3. URL


2008

 

 
    Zehetner, J., Danzer*, C., Collins*, S., Eckhardt, K., Gerber, P. A., Ballschmieter, P., Galvanovskis, J., Shimomura, K., Ashcroft, F. M., Thorens, B., Rorsman, P., Krek, W.: pVHL is a regulator of glucose metabolism and insulin secretion in pancreatic {beta} cells. Genes Dev 2008, 22:3135-46. URL

    Wisor, J. P., Pasumarthi, R. K., Gerashchenko, D., Thompson, C. L., Pathak, S., Sancar, A., Franken, P., Lein, E. S., Kilduff, T. S.: Sleep deprivation effects on circadian clock gene expression in the cerebral cortex parallel electroencephalographic differences among mouse strains. J Neurosci 2008, 28:7193-201. URL

    Wahli, W.: A gut feeling of the PXR, PPAR and NF-kappaB connection. J Intern Med 2008, 263:613-9. URL

    Wahli, W.: PPAR gamma: ally and foe in bone metabolism. Cell Metab 2008, 7:188-90. URL

    Wahli, W.: Nutrition, gestion de l'énergie et surpoids: que font donc nos gènes ? In Nouveaux Cahiers Volume 3. Edited by IJSLA; 2008: 44-78.

    Troy*, S., Soty*, M., Ribeiro*, L., Laval, L., Migrenne, S., Fioramonti, X., Pillot, B., Fauveau, V., Aubert, R., Viollet, B., Foretz, M., Leclerc, J., Duchampt, A., Zitoun, C., Thorens, B., Magnan, C., Mithieux*, G., Andreelli*, F.: Intestinal gluconeogenesis is a key factor for early metabolic changes after gastric bypass but not after gastric lap-band in mice. Cell Metab 2008, 8:201-11. URL

    Thorens, B.: Glucose sensing and the pathogenesis of obesity and type 2 diabetes. Int J Obes (Lond) 2008, 32 Suppl 6:S62-71. URL

    Stasiak, A.Z., Stasiak, A.: RecA-DNA complexes. (Condensation and commentary on the paper: Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures, by C. Yang and Pavletich, Nature, 453, 489-484). CHEMTRACTS-Biochemistry and Molecular Biology 2008, 21:399-405. URL

    Shanmugam, M., Hernandez, N.: Mitotic functions for SNAP45, a subunit of the small nuclear RNA-activating protein complex SNAPc. J Biol Chem 2008, 283:14845-56. URL

    Schepens, I., Boccalandro, H. E., Kami, C., Casal, J. J., Fankhauser, C.: PHYTOCHROME KINASE SUBSTRATE4 modulates phytochrome-mediated control of hypocotyl growth orientation. Plant Physiol 2008, 147:661-71. URL

    Rotman, N., Terreau-Haftek, Z., Lücke, S., Feige, J., Gelman, L., Desvergne, B., Wahli, W.: PPAR Disruption: Cellular Mechanisms and Physiological Consequences. CHIMIA 2008, 62:340-344. URL

    Rosso*, L., Marques*, A. C., Weier, M., Lambert, N., Lambot, M. A., Vanderhaeghen, P., Kaessmann, H.: Birth and rapid subcellular adaptation of a hominoid-specific CDC14 protein. PLoS Biol 2008, 6:e140. URL

    Rosso, L., Marques, A. C., Reichert, A. S., Kaessmann, H.: Mitochondrial targeting adaptation of the hominoid-specific glutamate dehydrogenase driven by positive Darwinian selection. PLoS Genet 2008, 4:e1000150. URL

    Rosso, L., Keller, L., Kaessmann, H., Hammond, R. L.: Mating system and avpr1a promoter variation in primates. Biol Lett 2008, 4:375-8. URL

    Rossetti, A. O., Heinzer, R., Espa, F., Tafti: Unilateral periodic leg movements during wakefulness and sleep after a parietal hemorrhage. Sleep Med 2008, 9:465-466. URL

    Rodriguez-Calvo, R., Serrano, L., Coll, T., Moullan, N., Sanchez, R. M., Merlos, M., Palomer, X., Laguna, J. C., Michalik, L., Wahli, W., Vazquez-Carrera, M.: Activation of peroxisome proliferator-activated receptor beta/delta inhibits lipopolysaccharide-induced cytokine production in adipocytes by lowering nuclear factor-kappaB activity via extracellular signal-related kinase 1/2. Diabetes 2008, 57:2149-57. URL

    Rawdon, E.J., Dobay, A., Kern, J., Millet, K., Piatek, M., Plunkett, P., Stasiak, A.: Scaling behavior and equilibrium lenghts of knotted polymers. Macromolecules 2008, 41:4444-4451. URL

    Rawdon, E., Kern, J., Piatek, M., Plunkett, P., Stasiak, A., Millet, K.: The effect of knotting on the shape of polymers. Macromolecules 2008, 41:8281-8287. URL

    Poussin, C., Hall, D., Minehira, K., Galzin, A. M., Tarussio, D., Thorens, B.: Different transcriptional control of metabolism and extracellular matrix in visceral and subcutaneous fat of obese and rimonabant treated mice. PLoS ONE 2008, 3:e3385. URL

    Potrzebowski*, L., Vinckenbosch*, N., Marques, A. C., Chalmel, F., Jegou, B., Kaessmann, H.: Chromosomal gene movements reflect the recent origin and biology of therian sex chromosomes. PLoS Biol 2008, 6:e80. URL

    Ploquin, M., Bransi, A., Paquet, E. R., Stasiak, A. Z., Stasiak, A., Yu, X., Cieslinska, A. M., Egelman, E. H., Moineau, S., Masson, J. Y.: Functional and structural basis for a bacteriophage homolog of human RAD52. Curr Biol 2008, 18:1142-6. URL

    Ortiz, M., Kaessmann, H., Zhang, K., Bashirova, A., Carrington, M., Quintana-Murci, L., Telenti, A.: The evolutionary history of the CD209 (DC-SIGN) family in humans and non-human primates. Genes Immun 2008, 9:483-92. URL

    Molina, J., Carmona-Mora, P., Chrast, J., Krall, P. M., Canales, C. P., Lupski, J. R., Reymond, A., Walz, K.: Abnormal social behaviors and altered gene expression rates in a mouse model for Potocki-Lupski syndrome. Hum Mol Genet 2008, 17:2486-95. URL

    Minehira, K., Young, S. G., Villanueva, C. J., Yetukuri, L., Oresic, M., Hellerstein, M. K., Farese, R. V., Jr., Horton, J. D., Preitner, F., Thorens, Tappy, L.: Blocking VLDL secretion causes hepatic steatosis but does not affect peripheral lipid stores or insulin sensitivity in mice. J Lipid Res 2008, 49:2038-44. URL

    Michalik*, L., Wahli*, W.: PPARs Mediate Lipid Signaling in Inflammation and Cancer. PPAR Res 2008, 2008:134059. URL

    Michalik, L., Wahli, W.: Tissue repair and cancer control through PPARs and their coregulators In Nuclear Receptors Co-regulators and Human Disease Edited by B. O'Malley, R. Kumar; London, Singapore: World Scientific Publishing; 2008: 409-440.

    Micale, L., Fusco, C., Augello, B., Napolitano, L. M., Dermitzakis, E. T., Meroni, G., Merla, G., Reymond, A.: Williams-Beuren syndrome TRIM50 encodes an E3 ubiquitin ligase. Eur J Hum Genet 2008, 16:1038-49. URL

    Marshall*, C. R., Young*, E. J., Pani, A. M., Freckmann, M. L., Lacassie, Y., Howald, C., Fitzgerald, K. K., Peippo, M., Morris, C. A., Shane, K., Priolo, M., Morimoto, M., Kondo, I., Manguoglu, E., Berker-Karauzum, S., Edery, P., Hobart, H. H., Mervis, C. B., Zuffardi, O., Reymond, A., Kaplan, P., Tassabehji, M., Gregg, R. G., Scherer, S. W., Osborne, L. R.: Infantile spasms is associated with deletion of the MAGI2 gene on chromosome 7q11.23-q21.11. Am J Hum Genet 2008, 83:106-11. URL

    Marques, A. C., Vinckenbosh, N., Brawand, D., Kaessmann, H.: Functional diversification of duplicate genes through subcellular adaptation of encoded proteins. Genome Biol 2008, 9:R54. URL

    Louis, M., Huber, T., Benton, R., Sakmar, T. P., Vosshall, L. B.: Bilateral olfactory sensory input enhances chemotaxis behavior. Nat Neurosci 2008, 11:187-99. URL

    Lorrain*, S., Allen*, T., Duek*, P. D., Whitelam, G. C., Fankhauser, C.: Phytochrome-mediated inhibition of shade avoidance involves degradation of growth-promoting bHLH transcription factors. Plant J 2008, 53:312-23. URL

    Klinger, S., Thorens, B.: Molecular biology of gluco-incretin function In Pancreatic Beta Cell in Health and Disease Edited by Seino, S., Bell, G.I.; Springer; 2008: 315-334.

    Klinger, S., Poussin, C., Debril, M. B., Dolci, W., Halban, P. A., Thorens, B.: Increasing GLP-1-induced beta-cell proliferation by silencing the negative regulators of signaling cAMP response element modulator-alpha and DUSP14. Diabetes 2008, 57:584-93. URL

    Jahoor, A, Patel, R, Bryan, R, Do, C, Krier, J, Watters, C, Wahli, W, Li, G, Williams, SC, Rumbaugh, KP: PPAR mediate host cell pro-inflammatory responses to P. aeruginosa autoinducer. Journal of Bacteriology 2008, 190:4408-4415..

    Isken, F., Pfeiffer, A. F., Nogueiras, R., Osterhoff, M. A., Ristow, M., Thorens, Tschop, M. H., Weickert, M. O.: Deficiency of Glucose-Dependent Insulinotropic Polypeptide (GIP) Receptor Prevents Ovariectomy-Induced Obesity in Mice. Am J Physiol Endocrinol Metab 2008, 295:E350-5. URL

    Hall*, M. G., Quignodon*, L., Desvergne, B.: Peroxisome Proliferator-Activated Receptor beta/delta in the Brain: Facts and Hypothesis. PPAR Res 2008, 2008:780452. URL

    Goldschmidt*, V., Ciuffi*, A., Ortiz, M., Brawand, D., Munoz, M., Kaessmann, H., Telenti, A.: Antiretroviral activity of ancestral TRIM5alpha. J Virol 2008, 82:2089-96. URL

    Genoud, T., Schweizer, F., Tscheuschler, A., Debrieux, D., Casal, J. J., Schafer, E., Hiltbrunner, A., Fankhauser, C.: FHY1 mediates nuclear import of the light-activated phytochrome A photoreceptor. PLoS Genet 2008, 4:e1000143. URL

    Genoud, T., Santa Cruz, M. T., Kulisic, T., Sparla, F., Fankhauser, C., Metraux, J. P.: The protein phosphatase 7 regulates phytochrome signaling in Arabidopsis. PLoS ONE 2008, 3:e2699. URL

    Gatfield, D., Schibler, U.: Circadian glucose homeostasis requires compensatory interference between brain and liver clocks. Proc Natl Acad Sci U S A 2008, 105:14753-4. URL

    Gari, K., Decaillet, C., Stasiak, A. Z., Stasiak, A., Constantinou, A.: The Fanconi anemia protein FANCM can promote branch migration of Holliday junctions and replication forks. Mol Cell 2008, 29:141-8. URL

    Franken, P. : Sleep homeostasis In Encyclopedia of Neuroscience Edited by Binder, M.D., Hirokawa, N., Windhorst, U.; Berlin, Heidelberg, New York: Springer; 2008: 3721-3725.

    Fiechter, V., Cameroni, E., Cerutti, L., De Virgilio, C., Barral, Y., Fankhauser, C.: The evolutionary conserved BER1 gene is involved in microtubule stability in yeast. Curr Genet 2008, 53:107-15. URL

    Ferdaoussi, M., Abdelli, S., Yang, J. Y., Cornu, M., Niederhauser, G., Favre, D., Widmann, C., Regazzi, R., Thorens, B., Waeber, G., Abderrahmani, A.: Exendin-4 protects {beta}-cells from interleukin 1{beta}-induced apoptosis by interfering with the c-Jun N-terminal kinases pathway. Diabetes 2008, 57:1205-15. URL

    Fankhauser, C., Chen, M.: Transposing phytochrome into the nucleus. Trends Plant Sci 2008, 13:596-601. URL

    Djebali*, S., Kapranov*, P., Foissac*, S., Lagarde*, J., Reymond*, A., Ucla, C., Wyss, C., Drenkow, J., Dumais, E., Murray, R. R., Lin, C., Szeto, D., Denoeud, F., Calvo, M., Frankish, A., Harrow, J., Makrythanasis, P., Vidal, M., Salehi-Ashtiani, K., Antonarakis, S. E., Gingeras, T. R., Guigo, R.: Efficient targeted transcript discovery via array-based normalization of RACE libraries. Nat Methods 2008, 5:629-35. URL

    Desvergne, B.: PPARdelta/beta: the lobbyist switching macrophage allegiance in favor of metabolism. Cell Metab 2008, 7:467-9. URL

    Dery, U., Coulombe, Y., Rodrigue, A., Stasiak, A., Richard, S., Masson, J. Y.: A glycine-arginine domain in control of the human MRE11 DNA repair protein. Mol Cell Biol 2008, 28:3058-69. URL

    de Lucas*, M., Daviere*, J. M., Rodriguez-Falcon*, M., Pontin, M., Iglesias-Pedraz, J. M., Lorrain, S., Fankhauser, C., Blazquez, M. A., Titarenko, E., Prat, S.: A molecular framework for light and gibberellin control of cell elongation. Nature 2008, 451:480-4. URL

    Dauvilliers, Y., Tafti, M.: The genetic basis of sleep disorders. Curr Pharm Des 2008, 14:3386-95. URL

    Darcy, I. K., Scharein, R. G., Stasiak, A.: 3D visualization software to analyze topological outcomes of topoisomerase reactions. Nucleic Acids Res 2008, 36:3515-21. URL

    Cueni, L., Canepari, M., Lujan, R., Emmenegger, Y., Watanabe, M., Bond, C. T., Franken, P., Adelman, J. P., Luthi, A.: T-type Ca2+ channels, SK2 channels and SERCAs gate sleep-related oscillations in thalamic dendrites. Nat Neurosci 2008, 11:683-92. URL

    Casals-Casas, C., Feige, J. N., Desvergne, B.: Interference of pollutants with PPARs: endocrine disruption meets metabolism. Int J Obes (Lond) 2008, 32 Suppl 6:S53-61. URL

    Burnier, Y., Dorier, J., Stasiak, A.: DNA supercoiling inhibits DNA knotting. Nucleic Acids Res 2008, 36:4956-63. URL

    Brawand, D., Wahli*, W., Kaessmann*, H.: Loss of egg yolk genes in mammals and the origin of lactation and placentation. PLoS Biol 2008, 6:e63. URL

    Boccalandro*, H. E., De Simone*, S. N., Bergmann-Honsberger, A., Schepens, I., Fankhauser, C., Casal, J. J.: PHYTOCHROME KINASE SUBSTRATE1 regulates root phototropism and gravitropism. Plant Physiol 2008, 146:108-15. URL

    Benton, R.: Chemical sensing in Drosophila. Curr Opin Neurobiol 2008, 18:357-63. URL

    Attanasio, C., Reymond, A., Humbert, R., Lyle, R., Kuehn, M. S., Neph, S., Sabo, P. J., Goldy, J., Weaver, M., Lee, K., Haydock, A., Dermitzakis, E. T., Dorschner, M. O., Antonarakis, S. E., Stamatoyannopoulos, J. A.: Assaying the regulatory potential of mammalian conserved non-coding sequences in human cells. Genome Biol 2008, 9:R168. URL

    Asher, G., Gatfield, D., Stratmann, M., Reinke, H., Dibner, C., Kreppel, F., Mostoslavsky, R., Alt, F. W., Schibler, U.: SIRT1 regulates circadian clock gene expression through PER2 deacetylation. Cell 2008, 134:317-28. URL

    Andretic, R., Franken, P., Tafti, M.: Genetics of sleep. Annu Rev Genet 2008, 42:361-88. URL


2007

 

 
    Zheng, D., Frankish, A., Baertsch, R., Kapranov, P., Reymond, A., Choo, S. W., Lu, Y., Denoeud, F., Antonarakis, S. E., Snyder, M., Ruan, Y., Wei, C. L., Gingeras, T. R., Guigo, R., Harrow, J., Gerstein, M. B.: Pseudogenes in the ENCODE regions: consensus annotation, analysis of transcription, and evolution. Genome Res 2007, 17:839-51. URL

    Yuan, C. C., Zhao, X., Florens, L., Swanson, S. K., Washburn, M. P., Hernandez, N.: CHD8 associates with human Staf and contributes to efficient U6 RNA polymerase III transcription. Mol Cell Biol 2007, 27:8729-38. URL

    Washietl, S., Pedersen, J. S., Korbel, J. O., Stocsits, C., Gruber, A. R., Hackermuller, J., Hertel, J., Lindemeyer, M., Reiche, K., Tanzer, A., Ucla, C., Wyss, C., Antonarakis, S. E., Denoeud, F., Lagarde, J., Drenkow, J., Kapranov, P., Gingeras, T. R., Guigo, R., Snyder, M., Gerstein, M. B., Reymond, A., Hofacker, I. L., Stadler, P. F.: Structured RNAs in the ENCODE selected regions of the human genome. Genome Res 2007, 17:852-64. URL

    Wang, H., Xie, H., Sun, X., Tranguch, S., Zhang, H., Jia, X., Wang, D., Das, S. K., Desvergne, B., Wahli, W., Dubois, R. N., Dey, S. K.: Stage-specific integration of maternal and embryonic PPARdelta signaling is critical to pregnancy success. J Biol Chem 2007, 282:37770-82. URL

    Tyagi, S., Chabes, A. L., Wysocka, J., Herr, W.: E2F activation of S phase promoters via association with HCF-1 and the MLL family of histone H3K4 methyltransferases. Mol Cell 2007, 27:107-19. URL

    Tudor, C., Feige, J. N., Pingali, H., Lohray, V. B., Wahli, W., Desvergne, B., Engelborghs, Y., Gelman, L.: Association with coregulators is the major determinant governing peroxisome proliferator-activated receptor mobility in living cells. J Biol Chem 2007, 282:4417-26 . URL

    Trupkin, S. A., Debrieux, D., Hiltbrunner, A., Fankhauser, C., Casal, J. J.: The serine-rich N-terminal region of Arabidopsis phytochrome A is required for protein stability. Plant Mol Biol 2007, 63:669-78. URL

    Tress, M. L., Martelli, P. L., Frankish, A., Reeves, G. A., Wesselink, J. J., Yeats, C., Olason, P. L., Albrecht, M., Hegyi, H., Giorgetti, A., Raimondo, D., Lagarde, J., Laskowski, R. A., Lopez, G., Sadowski, M. I., Watson, J. D., Fariselli, P., Rossi, I., Nagy, A., Kai, W., Storling, Z., Orsini, M., Assenov, Y., Blankenburg, H., Huthmacher, C., Ramirez, F., Schlicker, A., Denoeud, F., Jones, P., Kerrien, S., Orchard, S., Antonarakis, S. E., Reymond, A., Birney, E., Brunak, S., Casadio, R., Guigo, R., Harrow, J., Hermjakob, H., Jones, D. T., Lengauer, T., A. Orengo C, Patthy, L., Thornton, J. M., Tramontano, A., Valencia, A.: The implications of alternative splicing in the ENCODE protein complement. Proc Natl Acad Sci U S A 2007, 104:5495-500. URL

    Thorens, B.: Development and preclinical assessment of a bioartificial pancreas. Swiss Med Wkly 2007, 137 Suppl 155:68S-71S. URL

    Tan, N. S., Icre, G., Montagner, A., Bordier-ten-Heggeler, B., Wahli, W., Michalik, L.: The nuclear hormone receptor peroxisome proliferator-activated receptor beta/delta potentiates cell chemotactism, polarization, and migration. Mol Cell Biol 2007, 27:7161-75. URL

    Tafti, M., Ghyselinck, N. B.: Functional implication of the vitamin A signaling pathway in the brain. Arch Neurol 2007, 64:1706-11. URL

    Tafti, M., Franken, P.: Molecular analysis of sleep. Cold Spring Harb Symp Quant Biol 2007, 72:573-8. URL

    Tafti, M., Dauvilliers, Y., Overeem, S.: Narcolepsy and familial advanced sleep-phase syndrome: molecular genetics of sleep disorders. Curr Opin Genet Dev 2007, 17:222-7. URL

    Tafti, M.: Reply to 'Promotion of sleep by targeting the orexin system in rats, dogs and humans'. Nat Med 2007, 13:525-6; author reply 526. URL

    Tafti, M.: Quantitative genetics of sleep in inbred mice. Dialogues Clin Neurosci 2007, 9:273-8. URL

    Stienstra, R., Mandard, S., Tan, N. S., Wahli, W., Trautwein, C., Richardson, T. A., Lichtenauer-Kaligis, E., Kersten, S., Muller, M.: The Interleukin-1 receptor antagonist is a direct target gene of PPARalpha in liver. J Hepatol 2007, 46:869-77.. URL

    Reymond, A., Henrichsen, C. N., Harewood, L., Merla, G.: Side effects of genome structural changes. Curr Opin Genet Dev 2007, 17:381-6. URL

    Reina, J. H., Hernandez, N.: On a roll for new TRF targets. Genes Dev 2007, 21:2855-60. URL

    Plunkett, P., Piatek, M., Dobay, A., Kern, J.C., Millet, K.C., Stasiak, A., Rawdon, E.J.: Total curvature and total torsion of knotted polymers. Macromolecules 2007, 40:3860-3867.

    Ploquin, M., Petukhova, G. V., Morneau, D., Dery, U., Bransi, A., Stasiak, A., Camerini-Otero, R. D., Masson, J. Y.: Stimulation of fission yeast and mouse Hop2-Mnd1 of the Dmc1 and Rad51 recombinases. Nucleic Acids Res 2007, 35:2719-33. URL

    Pialat, J. B., Cho, T. H., Beuf, O., Joye, E., Moucharaffie, S., Langlois, J. B., Nemoz, C., Janier, M., Berthezene, Y., Nighoghossian, N., Desvergne, B., Wiart, M.: MRI monitoring of focal cerebral ischemia in peroxisome proliferator-activated receptor (PPAR)-deficient mice. NMR Biomed 2007, 20:335-42. URL

    Parmley, J. L., Urrutia, A. O., Potrzebowski, L., Kaessmann, H., Hurst, L. D.: Splicing and the evolution of proteins in mammals. PLoS Biol 2007, 5:e14. URL

    O'Hara, B. F., Ding, J., Bernat, R. L., Franken, P.: Genomic and proteomic approaches towards an understanding of sleep. CNS Neurol Disord Drug Targets 2007, 6:71-81. URL

    Nozue, K., Covington, M. F., Duek, P. D., Lorrain, S., Fankhauser, C., Harmer, S. L., Maloof, J. N.: Rhythmic growth explained by coincidence between internal and external cues. Nature 2007, 448:358-61. URL

    Michalik*, L., Zoete*, V., Krey, G., Grosdidier, A., Gelman, L., Chodanowski, P., Feige, J. N., Desvergne, B., Wahli**, W., Michielin**, O.: Combined simulation and mutagenesis analyses reveal the involvement of key residues for peroxisome proliferator-activated receptor alpha helix 12 dynamic behavior. J Biol Chem 2007, 282:9666-77. URL

    Michalik*, L., Wahli*, W*.: Peroxisome proliferator-activated receptors (PPARs) in skin health, repair and disease. Biochim Biophys Acta 2007, 1771:991-8 . URL

    Michalik, L., Wahli, W.: Guiding ligands to nuclear receptors. Cell 2007, 129:649-51. URL

    Michalik, L., Wahli, W.: Roles of the peroxisome proliferators-activated receptor (PPAR) alpha and beta/delta in skin wound healing. International Congress Series 2007, 1302:45-52.

    Marty, N., Dallaporta, M., Thorens, B.: Brain glucose sensing, counterregulation, and energy homeostasis. Physiology (Bethesda) 2007, 22:241-51. URL

    Maret, S., Dorsaz, S., Gurcel, L., Pradervand, S., Petit, B., Pfister, C., Hagenbuchle, O., O'Hara, B. F., Franken, P., Tafti, M.: Homer1a is a core brain molecular correlate of sleep loss. Proc Natl Acad Sci U S A 2007, 104:20090-5. URL

    Mandard, S., Stienstra, R., Escher, P., Tan, N. S., Kim, I., Gonzalez, F. J., Wahli, W., Desvergne, B., Muller, M., Kersten, S.: Glycogen synthase 2 is a novel target gene of peroxisome proliferator-activated receptors. Cell Mol Life Sci 2007, 64:1145-57. URL

    Lyle*, R., Prandini*, P., Osoegawa, K., ten Hallers, B., Humphray, S., Zhu, B., Eyras, E., Castelo, R., Bird, C. P., Gagos, S., Scott, C., Cox, A., Deutsch, S., Ucla, C., Cruts, M., Dahoun, S., She, X., Bena, F., Wang, S. Y., Van Broeckhoven, C., Eichler, E. E., Guigo, R., Rogers, J., de Jong, P. J., Reymond, A., Antonarakis, S. E.: Islands of euchromatin-like sequence and expressed polymorphic sequences within the short arm of human chromosome 21. Genome Res 2007, 17:1690-6. URL

    Li, R., Thorens, B., Loeken, M. R.: Expression of the gene encoding the high-Km glucose transporter 2 by the early postimplantation mouse embryo is essential for neural tube defects associated with diabetic embryopathy. Diabetologia 2007, 50:682-9. URL

    Lee, S., Horn, V., Julien, E., Liu, Y., Wysocka, J., Bowerman, B., Hengartner, M. O., Herr, W.: Epigenetic Regulation of Histone H3 Serine 10 Phosphorylation Status by HCF-1 Proteins in C. elegans and Mammalian Cells. PLoS ONE 2007, 2:e1213. URL

    Indra, A. K., Castaneda, E., Antal, M. C., Jiang, M., Messaddeq, N., Meng, X., Loehr, C. V., Gariglio, P., Kato, S., Wahli, W., Desvergne, B., Metzger, D., Chambon, P.: Malignant transformation of DMBA/TPA-induced papillomas and nevi in the skin of mice selectively lacking retinoid-X-receptor alpha in epidermal keratinocytes. J Invest Dermatol 2007, 127:1250-60. URL

    Gelman, L., Feige, J. N., Desvergne, B.: Molecular basis of selective PPARgamma modulation for the treatment of Type 2 diabetes. Biochim Biophys Acta 2007, 1771:1094-107. URL

    Gatfield, D., Schibler, U.: Physiology. Proteasomes keep the circadian clock ticking. Science 2007, 316:1135-6. URL

    Franken, P., Thomason, R., Heller, H. C., O'Hara, B. F.: A non-circadian role for clock-genes in sleep homeostasis: a strain comparison. BMC Neurosci 2007, 8:87. URL

    Franken, P.: The quality of waking and process S. Sleep 2007, 30:126-7. URL

    Flores, A. E., Flores, J. E., Deshpande, H., Picazo, J. A., Xie, X. S., Franken, P., Heller, H. C., Grahn, D. A., O'Hara, B. F.: Pattern recognition of sleep in rodents using piezoelectric signals generated by gross body movements. IEEE Trans Biomed Eng 2007, 54:225-33. URL

    Flammini, A., Stasiak, A.: Natural classification of knots In Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, Volume 463. 2007: 569-582.

    Flammini, A., Stasiak, A.: Natural classification of knots In Knot theory for scientific objects Edited by Kawwauchi, A.; Osaka: Osaka Municipal Universities Press; 2007: 293-306.

    Fierro-Fernandez, M., Hernandez, P., Krimer, D. B., Stasiak, A., Schvartzman, J. B.: Topological locking restrains replication fork reversal. Proc Natl Acad Sci U S A 2007, 104:1500-5. URL

    Feige, J. N., Gelman, L., Rossi, D., Zoete, V., Metivier, R., Tudor, C., Anghel, S. I., Grosdidier, A., Lathion, C., Engelborghs, Y., Michielin, O., Wahli, W., Desvergne, B.: The endocrine disruptor monoethyl-hexyl-phthalate is a selective peroxisome proliferator-activated receptor gamma modulator that promotes adipogenesis. J Biol Chem 2007, 282:19152-66. URL

    ENCODE_Consortium, authors_from_the_CIG:, Reymond, A., Chrast, J., Henrichsen, C. N.: Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature 2007, 447:799-816. URL

    Diao, Y., Stasiak, A.: Self-avoiding random walks and Olber's paradox. International Journal of Contemporary Mathematical Sciences 2007, 2:445-449.

    Desvergne, B.: RXR: From Partnership to Leadership in Metabolic Regulations. Vitam Horm 2007, 75:1-32. URL

    Desvergne, B.: PPARs special issue: anchoring the present to explore the future. Biochim Biophys Acta 2007, 1771:913-4. URL

    Desvergne, B.: Retinaldehyde: more than meets the eye. Nat Med 2007, 13:671-3. URL

    Denoeud*, F., Kapranov*, P., Ucla, C., Frankish, A., Castelo, R., Drenkow, J., Lagarde, J., Alioto, T., Manzano, C., Chrast, J., Dike, S., Wyss, C., Henrichsen, C. N., Holroyd, N., Dickson, M. C., Taylor, R., Hance, Z., Foissac, S., Myers, R. M., Rogers, J., Hubbard, T., Harrow, J., Guigo, R., Gingeras, T. R., Antonarakis, S. E., Reymond, A.: Prominent use of distal 5' transcription start sites and discovery of a large number of additional exons in ENCODE regions. Genome Res 2007, 17:746-59. URL

    Denissov, S., van Driel, M., Voit, R., Hekkelman, M., Hulsen, T., Hernandez, N., Grummt, I., Wehrens, R., Stunnenberg, H.: Identification of novel functional TBP-binding sites and general factor repertoires. Embo J 2007, 26:944-54. URL

    Cerf, C., Stasiak, A.: Linear behaviour of the writhe versus the number crossings in rational knots and links In Topology in Molecular Biology Edited by Monastyrsky, M.I.; Berlin, Heidelberg: Springer-Verlag; 2007: 111-125.

    Capotosti, F., Hsieh, J. J., Herr, W.: Species selectivity of mixed-lineage leukemia/trithorax and HCF proteolytic maturation pathways. Mol Cell Biol 2007, 27:7063-72. URL

    Cani, P. D., Holst, J. J., Drucker, D. J., Delzenne, N. M., Thorens, B., Burcelin, R., Knauf, C.: GLUT2 and the incretin receptors are involved in glucose-induced incretin secretion. Mol Cell Endocrinol 2007, 276:18-23. URL

    Burnier, Y., Weber, C., Flammini, A., Stasiak, A.: Local selection rules that can determine specific pathways of DNA unknotting by type II DNA topoisomerases. Nucleic Acids Res 2007, 35:5223-31. URL

    Berry*, A., Balard*, P., Coste, A., Olagnier, D., Lagane, C., Authier, H., Benoit-Vical, F., Lepert, J. C., Seguela, J. P., Magnaval, J. F., Chambon, P., Metzger, D., Desvergne, B., Wahli, W., Auwerx, J., Pipy, B.: IL-13 induces expression of CD36 in human monocytes through PPARgamma activation. Eur J Immunol 2007, 37:1642-52. URL

    Benton, R., Vannice, K. S., Vosshall, L. B.: An essential role for a CD36-related receptor in pheromone detection in Drosophila. Nature 2007, 450:289-93. URL

    Benton, R.: Sensitivity and specificity in Drosophila pheromone perception. Trends Neurosci 2007, 30:512-9. URL

    Behm-Ansmant, I., Gatfield, D., Rehwinkel, J., Hilgers, V., Izaurralde, E.: A conserved role for cytoplasmic poly(A)-binding protein 1 (PABPC1) in nonsense-mediated mRNA decay. EMBO J 2007, 26:1591-601. URL

    Bedu, E., Desplanches, D., Pequignot, J., Bordier, B., Desvergne, B.: Double gene deletion reveals the lack of cooperation between PPARalpha and PPARbeta in skeletal muscle. Biochem Biophys Res Commun 2007, 357:877-81. URL

    Banavar, J. R., Hoang, T. X., Maddocks, J. H., Maritan, A., Poletto, C., Stasiak, A., Trovato, A.: Structural motifs of biomolecules. Proc Natl Acad Sci U S A 2007, 104:17283-6. URL

    Asahina, K., Benton, R.: Smell and taste on a high: symposium on chemical senses: from genes to perception. EMBO Rep 2007, 8:634-8. URL

    Anghel, S. I., Wahli, W.: Fat poetry: a kingdom for PPARgamma. Cell Res 2007, 17:486-511. URL

    Anghel, S. I., Bedu, E., Vivier, C. D., Descombes, P., Desvergne, B., Wahli, W.: Adipose tissue integrity as a prerequisite for systemic energy balance: a critical role for peroxisome proliferator-activated receptor gamma. J Biol Chem 2007, 282:29946-57. URL


2006

 

 
    Weber, C., Stasiak, A., De Los Rios, P., Dietler, G.: Numerical simulation of gel electrophoresis of DNA knots in weak and strong electric fields. Biophys J 2006, 90:3100-5. URL

    Weber, C., De Los Rios, P., Dietler, G., Stasiak, A.: Simulations of electrophoretic collisions of DNA knots with gel obstacles. Journal of Physics: Condensed Matter 2006, 18:S161-S171. URL

    Wang, D., Wang, H., Guo, Y., Ning, W., Katkuri, S., Wahli, W., Desvergne, B., Dey, S. K., DuBois, R. N.: Crosstalk between peroxisome proliferator-activated receptor delta and VEGF stimulates cancer progression. Proc Natl Acad Sci U S A 2006, 103:19069-74. URL

    Vinckenbosch, N., Dupanloup, I., Kaessmann, H.: Evolutionary fate of retroposed gene copies in the human genome. Proc Natl Acad Sci U S A 2006, 103:3220-5. URL

    Vieu, E., Hernandez, N.: Actin's latest act: polymerizing to facilitate transcription?. Nat Cell Biol 2006, 8:650-1. URL

    Varnat, F., Michalik, L., Desvergne, B., Wahli, W.: PPARs: lipid sensors that regulate cell differentiation processes In Nutritional Genomics: Impact on Health and Disease Edited by Brigelius-Flohé, R. , Joost, H.G.; Weinheim: Wiley-VCH Verlag GmbH & Co; 2006: 117-131.

    Varnat, F., Heggeler, B. B., Grisel, P., Boucard, N., Corthesy-Theulaz, I., Wahli, W., Desvergne, B.: PPARbeta/delta regulates paneth cell differentiation via controlling the hedgehog signaling pathway. Gastroenterology 2006, 131:538-53. URL

    Varnat, F., Desvergne, B.: Authors Reply-PPARbeta/delta regulates paneth cell differentiation via controlling the hedgehog signaling pathway. Gastroenterology 2006, 131:1658-9.

    Tweedie, E., Artner, I., Crawford, L., Poffenberger, G., Thorens, B., Stein, R., Powers, A. C., Gannon, M.: Maintenance of hepatic nuclear factor 6 in postnatal islets impairs terminal differentiation and function of beta-cells. Diabetes 2006, 55:3264-70. URL

    Thorens, B.: A missing sugar prevents glucose entry: a new twist on insulin secretion. Cell Metab 2006, 3:3-5. URL

    Thorens, B.: A toggle for type 2 diabetes?. N Engl J Med 2006, 354:1636-8. URL

    Thorens, B.: [The entero-islet axis: role of the intestine and glycemic regulation]. Journ Annu Diabetol Hotel Dieu 2006, _:67-73. URL

    Schuler, M., Ali, F., Chambon, C., Duteil, D., Bornert, J. M., Tardivel, A., Desvergne, B., Wahli, W., Chambon, P., Metzger, D.: PGC1alpha expression is controlled in skeletal muscles by PPARbeta, whose ablation results in fiber-type switching, obesity, and type 2 diabetes. Cell Metab 2006, 4:407-14. URL

    Rotman, N., Michalik, L., Desvergne, B., Wahli, W.: PPARs in fetal and early postnatal development In Nuclear receptors in development (Advances in Developmental Biology Series, Vol.16) Edited by R. Taneja , PM Wassarman; Elsevier; 2006: 33-49.

    Rosa, A., Neumann, F.R., Gasser, S.M., Stasiak, A.: Long time behaviour of diffusing particles in constrained geometries applied to chromatin motion. Journal of Physics: Condensed Matter 2006, 18:S235-S243.

    Rosa, A., Maddocks, J. H., Neumann, F. R., Gasser, S. M., Stasiak, A.: Measuring limits of telomere movement on nuclear envelope. Biophys J 2006, 90:L24-6. URL

    Rissling, I., Frauscher, B., Kronenberg, F., Tafti, M., Stiasny-Kolster, K., Robyr, A. C., Korner, Y., Oertel, W. H., Poewe, W., Hogl, B., Moller, J. C.: Daytime sleepiness and the COMT val158met polymorphism in patients with Parkinson disease. Sleep 2006, 29:108-11. URL

    Reinke, H., Gatfield, D.: Genome-wide oscillation of transcription in yeast. Trends Biochem Sci 2006, 31:189-91. URL

    Reina, J. H., Azzouz, T. N., Hernandez, N.: Maf1, a New Player in the Regulation of Human RNA Polymerase III Transcription. PLoS ONE 2006, 1:e134. URL

    Parra, G., Reymond, A., Dabbouseh, N., Dermitzakis, E. T., Castelo, R., Thomson, T. M., Antonarakis, S. E., Guigo, R.: Tandem chimerism as a means to increase protein complexity in the human genome. Genome Res 2006, 16:37-44. URL

    Ortiz, M., Bleiber, G., Martinez, R., Kaessmann*, H., Telenti*, A.: Patterns of evolution of host proteins involved in retroviral pathogenesis. Retrovirology 2006, 3:11. URL

    Nadra, K., Anghel, S. I., Joye, E., Tan, N. S., Basu-Modak, S., Trono, D., Wahli, W., Desvergne, B.: Differentiation of trophoblast giant cells and their metabolic functions are dependent on peroxisome proliferator-activated receptor beta/delta. Mol Cell Biol 2006, 26:3266-81. URL

    Michels, A. A., Hernandez, N.: Does Pol I talk to Pol II? Coordination of RNA polymerases in ribosome biogenesis. Genes Dev 2006, 20:1982-5. URL

    Michalik, L., Wahli, W.: Involvement of PPAR nuclear receptors in tissue injury and wound repair. J Clin Invest 2006, 116:598-606. URL

    Michalik, L., Wahli, W.: PPARs and colon cancers : A curse or a cure? In Recent Advances in Gastrointestinal Carcinogenesis Edited by H. Bamba, S. Ota; Trivandrum: Transworld Research Network; 2006: 145-161.

    Michalik, L., Auwerx, J., Berger, J. P., Chatterjee, V. K., Glass, C. K., Gonzalez, F. J., Grimaldi, P. A., Kadowaki, T., Lazar, M. A., O'Rahilly, S., Palmer, C. N., Plutzky, J., Reddy, J. K., Spiegelman, B. M., Staels, B., Wahli, W.: International Union of Pharmacology. LXI. Peroxisome proliferator-activated receptors. Pharmacol Rev 2006, 58:726-41. URL

    Merla, G., Howald, C., Henrichsen, C. N., Lyle, R., Wyss, C., Zabot, M. T., Antonarakis, S. E., Reymond, A.: Submicroscopic deletion in patients with Williams-Beuren syndrome influences expression levels of the nonhemizygous flanking genes. Am J Hum Genet 2006, 79:332-41. URL

    Membrez, M., Hummler, E., Beermann, F., Haefliger, J. A., Savioz, R., Pedrazzini, T., Thorens, B.: GLUT8 is dispensable for embryonic development but influences hippocampal neurogenesis and heart function. Mol Cell Biol 2006, 26:4268-76. URL

    Mathe, Z., Dupraz, P., Rinsch, C., Thorens, B., Bosco, D., Zbinden, M., Morel, P., Berney, T., Pepper, M. S.: Tetracycline-regulated expression of VEGF-A in beta cells induces angiogenesis: improvement of engraftment following transplantation. Cell Transplant 2006, 15:621-36. URL

    Mandard, S., Zandbergen, F., van Straten, E., Wahli, W., Kuipers, F., Muller, M., Kersten, S.: The fasting-induced adipose factor/angiopoietin-like protein 4 is physically associated with lipoproteins and governs plasma lipid levels and adiposity. J Biol Chem 2006, 281:934-44. URL

    Lorrain, S., Genoud, T., Fankhauser, C.: Let there be light in the nucleus!. Curr Opin Plant Biol 2006, 9:509-14. URL

    Lathion, C., Michalik, L., Wahli, W.: Physiological ligands of PPARs in inflammation and lipid homeostasis. Future Lipidology 2006, 1:191-201.

    Lariguet, P., Schepens, I., Hodgson, D., Pedmale, U. V., Trevisan, M., Kami, C., de Carbonnel, M., Alonso, J. M., Ecker, J. R., Liscum, E., Fankhauser, C.: PHYTOCHROME KINASE SUBSTRATE 1 is a phototropin 1 binding protein required for phototropism. Proc Natl Acad Sci U S A 2006, 103:10134-9. URL

    Knauf, C., Rieusset, J., Foretz, M., Cani, P. D., Uldry, M., Hosokawa, M., Martinez, E., Bringart, M., Waget, A., Kersten, S., Desvergne, B., Gremlich, S., Wahli, W., Seydoux, J., Delzenne, N. M., Thorens, B., Burcelin, R.: Peroxisome proliferator-activated receptor-alpha-null mice have increased white adipose tissue glucose utilization, GLUT4, and fat mass: Role in liver and brain. Endocrinology 2006, 147:4067-78. URL

    Icre, G., Wahli, W., Michalik, L.: Functions of the peroxisome proliferator-activated receptor (PPAR) alpha and beta in skin homeostasis, epithelial repair, and morphogenesis. J Investig Dermatol Symp Proc 2006, 11:30-5. URL

    Huang, Y. S., Tafti, M., Guilleminault, C.: Daytime sleepiness with and without cataplexy in Chinese-Taiwanese patients. Sleep Med 2006, 7:454-7. URL

    Howald*, C., Merla*, G., Digilio, M. C., Amenta, S., Lyle, R., Deutsch, S., Choudhury, U., Bottani, A., Antonarakis, S. E., Fryssira, H., Dallapiccola, B., Reymond, A.: Two high throughput technologies to detect segmental aneuploidies identify new Williams-Beuren syndrome patients with atypical deletions. J Med Genet 2006, 43:266-73. URL

    Harrow*, J., Denoeud*, F., Frankish*, A., Reymond, A., Chen, C. K., Chrast, J., Lagarde, J., Gilbert, J. G., Storey, R., Swarbreck, D., Rossier, C., Ucla, C., Hubbard, T., Antonarakis, S. E., Guigo, R.: GENCODE: producing a reference annotation for ENCODE. Genome Biol 2006, 7 Suppl 1:S4 1-9. URL

    Hamimes, S., Bourgeon, D., Stasiak, A. Z., Stasiak, A., Van Dyck, E.: Nucleic acid-binding properties of the RRM-containing protein RDM1. Biochem Biophys Res Commun 2006, 344:87-94. URL

    Guigo*, R., Flicek*, P., Abril*, J. F., Reymond, A., Lagarde, J., Denoeud, F., Antonarakis, S., Ashburner, M., Bajic, V. B., Birney, E., Castelo, R., Eyras, E., Ucla, C., Gingeras, T. R., Harrow, J., Hubbard, T., Lewis, S. E., Reese*, M. G.: EGASP: the human ENCODE Genome Annotation Assessment Project. Genome Biol 2006, 7 Suppl 1:S2 1-31. URL

    Gelman, L., Feige, J. N., Tudor, C., Engelborghs, Y., Wahli, W., Desvergne, B.: Integrating nuclear receptor mobility in models of gene regulation. Nucl Recept Signal 2006, 4:e010. URL

    Franken, P., Gip, P., Hagiwara, G., Ruby, N. F., Heller, H. C.: Glycogen content in the cerebral cortex increases with sleep loss in C57BL/6J mice. Neurosci Lett 2006, 402:176-9. URL

    Franken, P., Dudley, C. A., Estill, S. J., Barakat, M., Thomason, R., O'Hara, B. F., McKnight, S. L.: NPAS2 as a transcriptional regulator of non-rapid eye movement sleep: genotype and sex interactions. Proc Natl Acad Sci U S A 2006, 103:7118-23. URL

    Feige, J. N., Gelman, L., Michalik, L., Desvergne, B., Wahli, W.: From molecular action to physiological outputs: peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions. Prog Lipid Res 2006, 45:120-59. URL

    Fankhauser, C., Lorrain, S. : Quand les plantes sortent de l'ombre. Pour la Science 2006,
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    Fankhauser, C., Bowler, C. : Biochemical and molecular analysis of signaling components In Photomorphogenesis in Plants Edited by Schaefer, E., Nagy, F.; Dortrescht: Kluwer Academic Publishers; 2006:

    Emran, F., Florens, L., Ma, B., Swanson, S. K., Washburn, M. P., Hernandez, N.: A role for Yin Yang-1 (YY1) in the assembly of snRNA transcription complexes. Gene 2006, 377:96-108. URL

    Dupanloup, I., Kaessmann, H.: Evolutionary simulations to detect functional lineage-specific genes. Bioinformatics 2006, 22:1815-22. URL

    Drake, J. A., Bird, C., Nemesh, J., Thomas, D. J., Newton-Cheh, C., Reymond, A., Excoffier, L., Attar, H., Antonarakis, S. E., Dermitzakis, E. T., Hirschhorn, J. N.: Conserved noncoding sequences are selectively constrained and not mutation cold spots. Nat Genet 2006, 38:223-7. URL

    Doerflinger, H., Benton, R., Torres, I. L., Zwart, M. F., St Johnston, D.: Drosophila anterior-posterior polarity requires actin-dependent PAR-1 recruitment to the oocyte posterior. Curr Biol 2006, 16:1090-5. URL

    Deutsch, S., Reymond, A.: The future is genome-wide. Genome Biol 2006, 7:324. URL

    Desvergne, B., Michalik, L., Wahli, W.: Transcriptional regulation of metabolism. Physiol Rev 2006, 86:465-514. URL

    Dauvilliers, Y., Tafti, M.: Molecular genetics and treatment of narcolepsy. Ann Med 2006, 38:252-62. URL

    Canaple, L., Rambaud, J., Dkhissi-Benyahya, O., Rayet, B., Tan, N. S., Michalik, L., Delaunay, F., Wahli, W., Laudet, V.: Reciprocal regulation of brain and muscle Arnt-like protein 1 and peroxisome proliferator-activated receptor alpha defines a novel positive feedback loop in the rodent liver circadian clock. Mol Endocrinol 2006, 20:1715-27. URL

    Bhattachrjeee, S.M., Micheletti, C., Stasiak, A.: Thermodynamics, kinetics and mechanics of biopolymers . Journal of Physics: Condensed Matter 2006, 18:preface. URL

    Benton, R., Sachse, S., Michnick, S. W., Vosshall, L. B.: Atypical membrane topology and heteromeric function of Drosophila odorant receptors in vivo. PLoS Biol 2006, 4:e20. URL

    Benton, R.: On the ORigin of smell: odorant receptors in insects. Cell Mol Life Sci 2006, 63:1579-85. URL

    Baumann, C. R., Kilic, E., Petit, B., Werth, E., Hermann, D. M., Tafti, M., Bassetti, C. L.: Sleep EEG changes after middle cerebral artery infarcts in mice: different effects of striatal and cortical lesions. Sleep 2006, 29:1339-44. URL

    Bady, I., Marty, N., Dallaporta, M., Emery, M., Gyger, J., Tarussio, D., Foretz, M., Thorens, B.: Evidence from glut2-null mice that glucose is a critical physiological regulator of feeding. Diabetes 2006, 55:988-95. URL

    Avallone, R., Demers, A., Rodrigue-Way, A., Bujold, K., Harb, D., Anghel, S., Wahli, W., Marleau, S., Ong, H., Tremblay, A.: A growth hormone-releasing peptide that binds scavenger receptor CD36 and ghrelin receptor up-regulates sterol transporters and cholesterol efflux in macrophages through a peroxisome proliferator-activated receptor gamma-dependent pathway. Mol Endocrinol 2006, 20:3165-78. URL

    Amzallag, A., Vaillant, C., Jacob, M., Unser, M., Bednar, J., Kahn, J. D., Dubochet, J., Stasiak, A., Maddocks, J. H.: 3D reconstruction and comparison of shapes of DNA minicircles observed by cryo-electron microscopy. Nucleic Acids Res 2006, 34:e125. URL

    Ali, F. Y., Egan, K., FitzGerald, G. A., Desvergne, B., Wahli, W., Bishop-Bailey, D., Warner, T. D., Mitchell, J. A.: Role of prostacyclin versus peroxisome proliferator-activated receptor beta receptors in prostacyclin sensing by lung fibroblasts. Am J Respir Cell Mol Biol 2006, 34:242-6. URL


2005

 

 
    Zandbergen, F., Mandard, S., Escher, P., Tan, N. S., Patsouris, D., Jatkoe, T., Rojas-Caro, S., Madore, S., Wahli, W., Tafuri, S., Muller, M., Kersten, S.: The G0/G1 switch gene 2 is a novel PPAR target gene. Biochem J 2005, 392:313-24. URL

    Yang, Z. Z., Tschopp, O., Di-Poi, N., Bruder, E., Baudry, A., Dummler, B., Wahli, W., Hemmings, B. A.: Dosage-dependent effects of Akt1/protein kinase Balpha (PKBalpha) and Akt3/PKBgamma on thymus, skin, and cardiovascular and nervous system development in mice. Mol Cell Biol 2005, 25:10407-18. URL

    Yang, J. Y., Walicki, J., Abderrahmani, A., Cornu, M., Waeber, G., Thorens, B., Widmann, C.: Expression of an uncleavable N-terminal RasGAP fragment in insulin-secreting cells increases their resistance toward apoptotic stimuli without affecting their glucose-induced insulin secretion. J Biol Chem 2005, 280:32835-42. URL

    Xie, X., Dumas, T., Tang, L., Brennan, T., Reeder, T., Thomas, W., Klein, R. D., Flores, J., O'Hara, B. F., Heller, H. C., Franken, P.: Lack of the alanine-serine-cysteine transporter 1 causes tremors, seizures, and early postnatal death in mice. Brain Res 2005, 1052:212-21. URL

    Widmer, M., Uldry, M., Thorens, B.: GLUT8 subcellular localization and absence of translocation to the plasma membrane in PC12 cells and hippocampal neurons. Endocrinology 2005, 146:4727-36. URL

    Wattenhofer, M., Sahin-Calapoglu, N., Andreasen, D., Kalay, E., Caylan, R., Braillard, B., Fowler-Jaeger, N., Reymond, A., Rossier, B. C., Karaguzel, A., Antonarakis, S. E.: A novel TMPRSS3 missense mutation in a DFNB8/10 family prevents proteolytic activation of the protein. Hum Genet 2005, 117:528-35. URL

    Wattenhofer, M., Reymond, A., Falciola, V., Charollais, A., Caille, D., Borel, C., Lyle, R., Estivill, X., Petersen, M. B., Meda, P., Antonarakis, S. E.: Different mechanisms preclude mutant CLDN14 proteins from forming tight junctions in vitro. Hum Mutat 2005, 25:543-9. URL

    Thorens, B.: [Gluco-incretin hormones in insulin secretion]. Med Sci (Paris) 2005, 21 Spec No:40-3. URL

    Tan, N. S., Michalik, L., Desvergne, B., Wahli, W.: Multiple expression control mechanisms of peroxisome proliferator-activated receptors and their target genes. J Steroid Biochem Mol Biol 2005, 93:99-105. URL

    Tan, N. S., Michalik, L., Desvergne, B., Wahli, W.: Genetic- or transforming growth factor-beta 1-induced changes in epidermal peroxisome proliferator-activated receptor beta/delta expression dictate wound repair kinetics. J Biol Chem 2005, 280:18163-70. URL

    Tafti, M., Maret, S., Dauvilliers, Y.: Genes for normal sleep and sleep disorders. Ann Med 2005, 37:580-9. URL

    Skrtic, S., Carlsson, L., Ljungberg, A., Linden, D., Michalik, L., Wahli, W., Oscarsson, J.: Decreased expression of peroxisome proliferator-activated receptor alpha and liver fatty acid binding protein after partial hepatectomy of rats and mice. Liver Int 2005, 25:33-40. URL

    Sellers, J. A., Hou, L., Schoenberg, D. R., Batistuzzo de Medeiros, S. R., Wahli, W., Shelness, G. S.: Microsomal triglyceride transfer protein promotes the secretion of Xenopus laevis vitellogenin A1. J Biol Chem 2005, 280:13902-5. URL

    Saxena, A., Ma, B., Schramm, L., Hernandez, N.: Structure-function analysis of the human TFIIB-related factor II protein reveals an essential role for the C-terminal domain in RNA polymerase III transcription. Mol Cell Biol 2005, 25:9406-18. URL

    Sauvageau, S., Stasiak, A. Z., Banville, I., Ploquin, M., Stasiak, A., Masson, J. Y.: Fission yeast rad51 and dmc1, two efficient DNA recombinases forming helical nucleoprotein filaments. Mol Cell Biol 2005, 25:4377-87. URL

    Rousseaux, C., Lefebvre, B., Dubuquoy, L., Lefebvre, P., Romano, O., Auwerx, J., Metzger, D., Wahli, W., Desvergne, B., Naccari, G. C., Chavatte, P., Farce, A., Bulois, P., Cortot, A., Colombel, J. F., Desreumaux, P.: Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator-activated receptor-gamma. J Exp Med 2005, 201:1205-15. URL

    Rehwinkel, J., Behm-Ansmant, I., Gatfield, D., Izaurralde, E.: A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing. RNA 2005, 11:1640-7. URL

    Planavila, A., Rodriguez-Calvo, R., Jove, M., Michalik, L., Wahli, W., Laguna, J. C., Vazquez-Carrera, M.: Peroxisome proliferator-activated receptor beta/delta activation inhibits hypertrophy in neonatal rat cardiomyocytes. Cardiovasc Res 2005, 65:832-41. URL

    Mutch, D. M., Wahli, W., Williamson, G.: Nutrigenomics and nutrigenetics: the emerging faces of nutrition. Faseb J 2005, 19:1602-16. URL

    Millet, K., Dobay, A., Stasiak, A.: Linear random knots and their scaling behaviour. Macromolecules 2005, 38:601-606.

    Michalik, L., Feige, J. N., Gelman, L., Pedrazzini, T., Keller, H., Desvergne, B., Wahli, W.: Selective expression of a dominant-negative form of peroxisome proliferator-activated receptor in keratinocytes leads to impaired epidermal healing. Mol Endocrinol 2005, 19:2335-48. URL

    Metzger, D., Imai, T., Jiang, M., Takukawa, R., Desvergne, B., Wahli, W., Chambon, P.: Functional role of RXRs and PPARgamma in mature adipocytes. Prostaglandins Leukot Essent Fatty Acids 2005, 73:51-8. URL

    Mehenni, H., Lin-Marq, N., Buchet-Poyau, K., Reymond, A., Collart, M. A., Picard, D., Antonarakis, S. E.: LKB1 interacts with and phosphorylates PTEN: a functional link between two proteins involved in cancer predisposing syndromes. Hum Mol Genet 2005, 14:2209-19. URL

    Marty, N., Dallaporta, M., Foretz, M., Emery, M., Tarussio, D., Bady, I., Binnert, C., Beermann, F., Thorens, B.: Regulation of glucagon secretion by glucose transporter type 2 (glut2) and astrocyte-dependent glucose sensors. J Clin Invest 2005, 115:3545-53. URL

    Marques*, A. C., Dupanloup*, I., Vinckenbosch, N., Reymond, A., Kaessmann, H.: Emergence of young human genes after a burst of retroposition in primates. PLoS Biol 2005, 3:e357. URL

    Maret, S., Tafti, M.: Genetics of narcolepsy and other major sleep disorders. Swiss Med Wkly 2005, 135:662-5. URL

    Maret, S., Franken, P., Dauvilliers, Y., Ghyselinck, N. B., Chambon, P., Tafti, M.: Retinoic acid signaling affects cortical synchrony during sleep. Science 2005, 310:111-3. URL

    Letavernier, E., Perez, J., Joye, E., Bellocq, A., Fouqueray, B., Haymann, J. P., Heudes, D., Wahli, W., Desvergne, B., Baud, L.: Peroxisome proliferator-activated receptor beta/delta exerts a strong protection from ischemic acute renal failure. J Am Soc Nephrol 2005, 16:2395-402. URL

    Lariguet, P, Fankhauser, C: The effect of the light and gravity on hypocotyl growth orientation In Light Sensing in Plants Edited by Masamitsu, Wada, Ken-ichiro, Shimazaki, Moritoshi, Iino; Tokyo: Springer Japan; 2005: 277-284.

    Kostadinova, R., Wahli, W., Michalik, L.: PPARs in diseases: control mechanisms of inflammation. Curr Med Chem 2005, 12:2995-3009. URL

    Klejman, M. P., Zhao, X., van Schaik, F. M., Herr, W., Timmers, H. T.: Mutational analysis of BTAF1-TBP interaction: BTAF1 can rescue DNA-binding defective TBP mutants. Nucleic Acids Res 2005, 33:5426-36. URL

    Kim, Y. S., Kim, J. M., Jung, D. L., Kang, J. E., Lee, S., Kim, J. S., Seol, W., Shin, H. C., Kwon, H. S., Van Lint, C., Hernandez, N., Hur, M. W.: Artificial zinc finger fusions targeting Sp1-binding sites and the trans-activator-responsive element potently repress transcription and replication of HIV-1. J Biol Chem 2005, 280:21545-52. URL

    Jurvansuu, J., Raj, K., Stasiak, A., Beard, P.: Viral transport of DNA damage that mimics a stalled replication fork. J Virol 2005, 79:569-80. URL

    Hiltbrunner, A., Viczian, A., Bury, E., Tscheuschler, A., Kircher, S., Toth, R., Honsberger, A., Nagy, F., Fankhauser, C., Schafer, E.: Nuclear accumulation of the phytochrome A photoreceptor requires FHY1. Curr Biol 2005, 15:2125-30. URL

    Hamimes, S., Arakawa, H., Stasiak, A. Z., Kierzek, A. M., Hirano, S., Yang, Y. G., Takata, M., Stasiak, A., Buerstedde, J. M., Van Dyck, E.: RDM1, a novel RNA recognition motif (RRM)-containing protein involved in the cell response to cisplatin in vertebrates. J Biol Chem 2005, 280:9225-35. URL

    Gremlich, S., Nolan, C., Roduit, R., Burcelin, R., Peyot, M. L., Delghingaro-Augusto, V., Desvergne, B., Michalik, L., Prentki, M., Wahli, W.: Pancreatic islet adaptation to fasting is dependent on peroxisome proliferator-activated receptor alpha transcriptional up-regulation of fatty acid oxidation. Endocrinology 2005, 146:375-82. URL

    Genolet, R, Michalik, L, Wahli, W: Peroxisome Proliferator Activated Receptors In Signaling pathways in liver diseases Edited by Dufour, J-F, Clavien, P-A; Berlin, Heidelberg, New York: Springer; 2005: 267-280.

    Genolet, R., Kersten, S., Braissant, O., Mandard, S., Tan, N. S., Bucher, P., Desvergne, B., Michalik, L., Wahli, W.: Promoter rearrangements cause species-specific hepatic regulation of the glyoxylate reductase/hydroxypyruvate reductase gene by the peroxisome proliferator-activated receptor alpha. J Biol Chem 2005, 280:24143-52. URL

    Gelman, L., Michalik, L., Desvergne, B., Wahli, W.: Kinase signaling cascades that modulate peroxisome proliferator-activated receptors. Curr Opin Cell Biol 2005, 17:216-22. URL

    Foretz, M., Ancellin, N., Andreelli, F., Saintillan, Y., Grondin, P., Kahn, A., Thorens, B., Vaulont, S., Viollet, B.: Short-term overexpression of a constitutively active form of AMP-activated protein kinase in the liver leads to mild hypoglycemia and fatty liver. Diabetes 2005, 54:1331-9. URL

    Feige, J. N., Sage, D., Wahli, W., Desvergne, B., Gelman, L.: PixFRET, an ImageJ plug-in for FRET calculation that can accommodate variations in spectral bleed-throughs. Microsc Res Tech 2005, 68:51-8. URL

    Feige, J. N., Gelman, L., Tudor, C., Engelborghs, Y., Wahli, W., Desvergne, B.: Fluorescence imaging reveals the nuclear behavior of peroxisome proliferator-activated receptor/retinoid X receptor heterodimers in the absence and presence of ligand. J Biol Chem 2005, 280:17880-90. URL

    Eyras, E., Reymond, A., Castelo, R., Bye, J. M., Camara, F., Flicek, P., Huckle, E. J., Parra, G., Shteynberg, D. D., Wyss, C., Rogers, J., Antonarakis, S. E., Birney, E., Guigo, R., Brent, M. R.: Gene finding in the chicken genome. BMC Bioinformatics 2005, 6:131. URL

    Eumorphia_Consortium, Authors_from_the_CIG: , Wahli, W., Delgado, MB., Desvergne, B., Michalik, L., Bedu, E.: EMPReSS: standardised phenotype screens for functional annotation of the mouse genome. Nat Genet 2005, 37:1155. URL

    Duek, P. D., Fankhauser, C.: bHLH class transcription factors take centre stage in phytochrome signalling. Trends Plant Sci 2005, 10:51-4. URL

    Dobay, A., Diao, Y., Dubochet, J., Stasiak, A.: Scaling of the average crossing number in equilateral random walks, knots and proteins In Physical and numerical models in knot theory; including applications to the life sciences Edited by Calvo, J.A., Millet, K.C., Rawdon, E.J., Stasiak, A.; Singapore: World Scientific Publishing; 2005: 219-231.

    Dijk, D.J. , Franken, P. : Interaction of sleep homeostasis and circadian rhythmicity: dependent or independent systems? In Principles and practice of sleep medecine Edited by Kryger, M.H., Roth T., Dement W.; Philadelphia, PA: Saunders/Elsevier; 2005: 418–434.

    Diao, Y., Dobay, A., Stasiak, A.: The average intercrossing number of equilateral random walks and polygons. Journal Physics A: Mathematical and General 2005, 38:7601-7616.

    Di-Poi, N., Ng, C. Y., Tan, N. S., Yang, Z., Hemmings, B. A., Desvergne, B., Michalik, L., Wahli, W.: Epithelium-mesenchyme interactions control the activity of peroxisome proliferator-activated receptor beta/delta during hair follicle development. Mol Cell Biol 2005, 25:1696-712. URL

    Di-Poi, N., Desvergne, B., Michalik, L., Wahli, W.: Transcriptional repression of peroxisome proliferator-activated receptor beta/delta in murine keratinocytes by CCAAT/enhancer-binding proteins. J Biol Chem 2005, 280:38700-10. URL

    Dermitzakis, E. T., Reymond, A., Antonarakis, S. E.: Conserved non-genic sequences - an unexpected feature of mammalian genomes. Nat Rev Genet 2005, 6:151-7. URL

    Debril, M. B., Dubuquoy, L., Feige, J. N., Wahli, W., Desvergne, B., Auwerx, J., Gelman, L.: Scaffold attachment factor B1 directly interacts with nuclear receptors in living cells and represses transcriptional activity. J Mol Endocrinol 2005, 35:503-17. URL

    Dauvilliers, Y., Maret, S., Tafti, M.: Genetics of normal and pathological sleep in humans. Sleep Med Rev 2005, 9:91-100. URL

    Castelo, R., Reymond, A., Wyss, C., Camara, F., Parra, G., Antonarakis, S. E., Guigo, R., Eyras, E.: Comparative gene finding in chicken indicates that we are closing in on the set of multi-exonic widely expressed human genes. Nucleic Acids Res 2005, 33:1935-9. URL

    Calvo, J.A., Millet, K.C., Rawdon, E.J., Stasiak, A., Kaufman, L.H.: Physical and numerical models in knots theory, including applications to the life sciences. Knots and everything 2005, 36:

    Bugreev, D. V., Golub, E. I., Stasiak, A. Z., Stasiak, A., Mazin, A. V.: Activation of human meiosis-specific recombinase Dmc1 by Ca2+. J Biol Chem 2005, 280:26886-95. URL

    Bonafe, L., Dermitzakis, E. T., Unger, S., Greenberg, C. R., Campos-Xavier, B. A., Zankl, A., Ucla, C., Antonarakis, S. E., Superti-Furga, A., Reymond, A.: Evolutionary comparison provides evidence for pathogenicity of RMRP mutations. PLoS Genet 2005, 1:e47. URL

    Bedu, E., Wahli, W., Desvergne, B.: Peroxisome proliferator-activated receptor beta/delta as a therapeutic target for metabolic diseases. Expert Opin Ther Targets 2005, 9:861-73. URL


2004

 

 
    Yokoyama, A., Wang, Z., Wysocka, J., Sanyal, M., Aufiero, D. J., Kitabayashi, I., Herr, W., Cleary, M. L.: Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression. Mol Cell Biol 2004, 24:5639-49. URL

    Wang, D., Wang, H., Shi, Q., Katkuri, S., Walhi, W., Desvergne, B., Das, S. K., Dey, S. K., DuBois, R. N.: Prostaglandin E(2) promotes colorectal adenoma growth via transactivation of the nuclear peroxisome proliferator-activated receptor delta. Cancer Cell 2004, 6:285-95. URL

    Wang, D., Wang, H., Shi, Q., Katkuri, S., Wahli, W., Desvergne, B., Das, S.K., Dey, S.K., DuBois, R.N.: Prostaglandin E(2) promotes colorectal adenoma growth via transactivation of the nuclear peroxisome proliferator-activated receptor delta. Cancer cell 2004, 6:285-95.

    Wahli, W., Michalik, L., Desvergne, B.: PPARs in health and disease : central roles in energy homeostasis and tissue repair. BIO 2004, 11:26-31.

    Uldry, M., Thorens, B.: The SLC2 family of facilitated hexose and polyol transporters. Pflugers Arch 2004, 447:480-9. URL

    Uldry, M., Steiner, P., Zurich, M. G., Beguin, P., Hirling, H., Dolci, W., Thorens, B.: Regulated exocytosis of an H+/myo-inositol symporter at synapses and growth cones. Embo J 2004, 23:531-40. URL

    Tubon, T. C., Tansey, W. P., Herr, W.: A nonconserved surface of the TFIIB zinc ribbon domain plays a direct role in RNA polymerase II recruitment. Mol Cell Biol 2004, 24:2863-74. URL

    Thorens, B., Larsen, P. J.: Gut-derived signaling molecules and vagal afferents in the control of glucose and energy homeostasis. Curr Opin Clin Nutr Metab Care 2004, 7:471-8. URL

    Thorens, B.: Mechanisms of glucose sensing and multiplicity of glucose sensors. Ann Endocrinol (Paris) 2004, 65:9-12. URL

    Thorens, B.: [GIP and GLP-1: multiplicity of regulator mechanisms for insulin secretion]. Journ Annu Diabetol Hotel Dieu 2004, _:111-25. URL

    Thorens, B.: Physiology of GLP-1--lessons from glucoincretin receptor knockout mice. Horm Metab Res 2004, 36:766-70. URL

    Thorens, B.: The hepatoportal glucose sensor. Mechanisms of glucose sensing and signal transduction. In Glucokinase and Glycemic Disease: From Basics to Novel Therapeutics. Front Diabetes Volume 16. Edited by Matschinsky, FM., Magnuson, MA.; Basel: Karger; 2004: 327-38.

    Tan, N. S., Michalik, L., Di-Poi, N., Ng, C. Y., Mermod, N., Roberts, A. B., Desvergne, B., Wahli, W.: Essential role of Smad3 in the inhibition of inflammation-induced PPARbeta/delta expression. Embo J 2004, 23:4211-21. URL

    Tan, N. S., Michalik, L., Di-Poi, N., Desvergne, B., Wahli, W.: Critical roles of the nuclear receptor PPARbeta (peroxisome-proliferator-activated receptor beta) in skin wound healing. Biochem Soc Trans 2004, 32:97-102. URL

    Tan, N. S., Michalik, L., Desvergne, B., Wahli, W.: Peroxisome proliferator-activated receptor-beta as a target for wound healing drugs. Expert Opin Ther Targets 2004, 8:39-48. URL

    Tafti, M., Franken, P.: Genetics of delta and theta activities during sleep: Deficiency in short-chain fatty acid -oxidation affects theta oscillations during sleep. Sleep Biol Rhythms 2004, 2:34-5.

    Stasiak, A.: Explaining explanations. (Review of the book : "Explanations: styles of explanation in science", by J. Cornwell, Oxford University Press, Oyford, UK). EMBO reports 2004, 5:854.

    Stasiak, A.: DNA circles In Living matter: a new challenge to physicists ? Edited by De Los Rios, P., Dietler, G., Fourcade, B., Peroni, C.; Frontier Group; 2004: 13-51.

    Stasiak, A., Reese*, M. G.: Eight Controversies. (Review of the book : "Eight preposterous propositions", by R. Ehrlich, Princeton University Press, Princeton, USA). EMBO reports 2004, 5:239.

    Stasiak, A.: Another strand to the DNA story. (Review of the book : "The third man of the double helix", by M. Wilkins, Oxford University Press, Oxford, UK). EMBO reports 2004, 5:21.

    Sineshchekov, V., Fankhauser, C.: PKS1 and PKS2 affect the phyA state in etiolated Arabidopsis seedlings. Photochem Photobiol Sci 2004, 3:608-11. URL

    Schvartzman, J. B., Stasiak, A.: A topological view of the replicon. EMBO Rep 2004, 5:256-61. URL

    Schepens, I., Duek, P., Fankhauser, C.: Phytochrome-mediated light signalling in Arabidopsis. Curr Opin Plant Biol 2004, 7:564-9. URL

    Sanguino, E., Ramon, M., Michalik, L., Wahli, W., Alegret, M., Sanchez, R. M., Vazquez-Carrera, M., Laguna, J. C.: Lack of hypotriglyceridemic effect of gemfibrozil as a consequence of age-related changes in rat liver PPARalpha. Biochem Pharmacol 2004, 67:157-66. URL

    Rieusset, J., Seydoux, J., Anghel, S. I., Escher, P., Michalik, L., Soon Tan, N., Metzger, D., Chambon, P., Wahli, W., Desvergne, B.: Altered growth in male peroxisome proliferator-activated receptor gamma (PPARgamma) heterozygous mice: involvement of PPARgamma in a negative feedback regulation of growth hormone action. Mol Endocrinol 2004, 18:2363-77. URL

    Preitner, F., Ibberson, M., Franklin, I., Binnert, C., Pende, M., Gjinovci, A., Hansotia, T., Drucker, D. J., Wollheim, C., Burcelin, R., Thorens, B.: Gluco-incretins control insulin secretion at multiple levels as revealed in mice lacking GLP-1 and GIP receptors. J Clin Invest 2004, 113:635-45. URL

    Patsouris, D., Mandard, S., Voshol, P. J., Escher, P., Tan, N. S., Havekes, L. M., Koenig, W., Marz, W., Tafuri, S., Wahli, W., Muller, M., Kersten, S.: PPARalpha governs glycerol metabolism. J Clin Invest 2004, 114:94-103. URL

    Palacios, I. M., Gatfield, D., St Johnston, D., Izaurralde, E.: An eIF4AIII-containing complex required for mRNA localization and nonsense-mediated mRNA decay. Nature 2004, 427:753-7. URL

    Mutch, D. M., Anderle, P., Fiaux, M., Mansourian, R., Vidal, K., Wahli, W., Williamson, G., Roberts, M. A.: Regional variations in ABC transporter expression along the mouse intestinal tract. Physiol Genomics 2004, 17:11-20. URL

    Michalik, L., Desvergne, B., Wahli, W.: Peroxisome-proliferator-activated receptors and cancers: complex stories. Nat Rev Cancer 2004, 4:61-70. URL

    Merla, G., Howald, C., Antonarakis, S. E., Reymond, A.: The subcellular localization of the ChoRE-binding protein, encoded by the Williams-Beuren syndrome critical region gene 14, is regulated by 14-3-3. Hum Mol Genet 2004, 13:1505-14. URL

    Menzel, O., Vellai, T., Takacs-Vellai, K., Reymond, A., Mueller, F., Antonarakis, S. E., Guipponi, M.: The Caenorhabditis elegans ortholog of C21orf80, a potential new protein O-fucosyltransferase, is required for normal development. Genomics 2004, 84:320-30. URL

    Menzel, O., Bekkeheien, R. C., Reymond, A., Fukai, N., Boye, E., Kosztolanyi, G., Aftimos, S., Deutsch, S., Scott, H. S., Olsen, B. R., Antonarakis, S. E., Guipponi, M.: Knobloch syndrome: novel mutations in COL18A1, evidence for genetic heterogeneity, and a functionally impaired polymorphism in endostatin. Hum Mutat 2004, 23:77-84. URL

    Mao-Qiang, M., Fowler, A. J., Schmuth, M., Lau, P., Chang, S., Brown, B. E., Moser, A. H., Michalik, L., Desvergne, B., Wahli, W., Li, M., Metzger, D., Chambon, P. H., Elias, P. M., Feingold, K. R.: Peroxisome-proliferator-activated receptor (PPAR)-gamma activation stimulates keratinocyte differentiation. J Invest Dermatol 2004, 123:305-12. URL

    Mandard, S., Zandbergen, F., Tan, N. S., Escher, P., Patsouris, D., Koenig, W., Kleemann, R., Bakker, A., Veenman, F., Wahli, W., Muller, M., Kersten, S.: The direct peroxisome proliferator-activated receptor target fasting-induced adipose factor (FIAF/PGAR/ANGPTL4) is present in blood plasma as a truncated protein that is increased by fenofibrate treatment. J Biol Chem 2004, 279:34411-20. URL

    Liu, Y., Stasiak, A. Z., Masson, J. Y., McIlwraith, M. J., Stasiak, A., West, S. C.: Conformational changes modulate the activity of human RAD51 protein. J Mol Biol 2004, 337:817-27. URL

    Larkin, J. E., Yokogawa, T., Heller, H. C., Franken, P., Ruby, N. F.: Homeostatic regulation of sleep in arrhythmic Siberian hamsters. Am J Physiol Regul Integr Comp Physiol 2004, 287:R104-11. URL

    Lariguet, P., Fankhauser, C.: Hypocotyl growth orientation in blue light is determined by phytochrome A inhibition of gravitropism and phototropin promotion of phototropism. Plant J 2004, 40:826-34. URL

    Khatami, R., Maret, S., Werth, E., Retey, J., Schmid, D., Maly, F., Tafti, M., Bassetti, C. L.: Monozygotic twins concordant for narcolepsy-cataplexy without any detectable abnormality in the hypocretin (orexin) pathway. Lancet 2004, 363:1199-200. URL

    Kersten, S., Escher, P., Tafuri, S., Wahli, W.: Understanding the coordinated effects of PPARs on lipid metabolism using microarrays In Unraveling Lipid Metabolism with Microarrays Taylor and Francis Books, CRC Press; 2004: 249-263.

    Julien, E., Herr, W.: A switch in mitotic histone H4 lysine 20 methylation status is linked to M phase defects upon loss of HCF-1. Mol Cell 2004, 14:713-25. URL

    Jove, M., Salla, J., Planavila, A., Cabrero, A., Michalik, L., Wahli, W., Laguna, J. C., Vazquez-Carrera, M.: Impaired expression of NADH dehydrogenase subunit 1 and PPARgamma coactivator-1 in skeletal muscle of ZDF rats: restoration by troglitazone. J Lipid Res 2004, 45:113-23. URL

    International Chicken Genome Sequencing Consortium _CIG_Members: Kaessmann, H., Reymond, A.: Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution. Nature 2004, 432:695-716. URL

    Imai, T., Takakuwa, R., Marchand, S., Dentz, E., Bornert, J. M., Messaddeq, N., Wendling, O., Mark, M., Desvergne, B., Wahli, W., Chambon, P., Metzger, D.: Peroxisome proliferator-activated receptor gamma is required in mature white and brown adipocytes for their survival in the mouse. Proc Natl Acad Sci U S A 2004, 101:4543-7. URL

    Ijpenberg, A., Tan, N. S., Gelman, L., Kersten, S., Seydoux, J., Xu, J., Metzger, D., Canaple, L., Chambon, P., Wahli, W., Desvergne, B.: In vivo activation of PPAR target genes by RXR homodimers. Embo J 2004, 23:2083-91. URL

    Hu, P., Wu, S., Hernandez, N.: A role for beta-actin in RNA polymerase III transcription. Genes Dev 2004, 18:3010-5. URL

    Hu, P., Samudre, K., Wu, S., Sun, Y., Hernandez, N.: CK2 phosphorylation of Bdp1 executes cell cycle-specific RNA polymerase III transcription repression. Mol Cell 2004, 16:81-92. URL

    Genolet, R., Wahli, W., Michalik, L.: PPARs as drug targets to modulate inflammatory responses?. Curr Drug Targets Inflamm Allergy 2004, 3:361-75. URL

    Gatfield, D., Izaurralde, E.: Nonsense-mediated messenger RNA decay is initiated by endonucleolytic cleavage in Drosophila. Nature 2004, 429:575-8. URL

    Gachon, F., Fonjallaz, P., Damiola, F., Gos, P., Kodama, T., Zakany, J., Duboule, D., Petit, B., Tafti, M., Schibler, U.: The loss of circadian PAR bZip transcription factors results in epilepsy. Genes Dev 2004, 18:1397-412. URL

    Frauscher, B., Hogl, B., Maret, S., Wolf, E., Brandauer, E., Wenning, G. K., Kronenberg, M. F., Kronenberg, F., Tafti, M., Poewe, W.: Association of daytime sleepiness with COMT polymorphism in patients with parkinson disease: a pilot study. Sleep 2004, 27:733-6. URL

    Foretz, M., Thorens, B.: The facilitative glucose transporter 2: pathophysiological role in mouse and human In Membrane Transporter Diseases Edited by Broer, S., Wagner, CA.; Kluwer Academic/Plenum Publishers; 2004: 175-90.

    Flammini, A., Maritan, A., Stasiak, A.: Simulations of action of DNA topoisomerases to investigate boundaries and shapes of spaces of knots. Biophys J 2004, 87:2968-75. URL

    Fankhauser, C., Casal, J. J.: Phenotypic characterization of a photomorphogenic mutant. Plant J 2004, 39:747-60. URL

    ENCODE_Consortium, author_from_the_CIG:, Reymond, A.: The ENCODE (ENCyclopedia Of DNA Elements) Project. Science 2004, 306:636-40. URL

    Emerson*, J. J., Kaessmann*, H., Betran, E., Long, M.: Extensive gene traffic on the mammalian X chromosome. Science 2004, 303:537-40. URL

    Duek, P. D., Elmer, M. V., van Oosten, V. R., Fankhauser, C.: The degradation of HFR1, a putative bHLH class transcription factor involved in light signaling, is regulated by phosphorylation and requires COP1. Curr Biol 2004, 14:2296-301. URL

    Di-Poi, N., Michalik, L., Desvergne, B., Wahli, W.: Functions of peroxisome proliferator-activated receptors (PPAR) in skin homeostasis. Lipids 2004, 39:1093-9. URL

    Desvergne, B., Michalik, L., Wahli, W.: Be fit or be sick: peroxisome proliferator-activated receptors are down the road. Mol Endocrinol 2004, 18:1321-32. URL

    Dermitzakis, E. T., Reymond, A.: DNA sequence evolution and phylogenetic footprinting In Mammalian genomics Edited by Ruvinsky, A., Marshall Graves, J. A.; CABI Publishing; 2004: 301-16.

    Dermitzakis, E. T., Kirkness, E., Schwarz, S., Birney, E., Reymond, A., Antonarakis, S. E.: Comparison of human chromosome 21 conserved nongenic sequences (CNGs) with the mouse and dog genomes shows that their selective constraint is independent of their genic environment. Genome Res 2004, 14:852-9. URL

    de Fourmestraux, V., Neubauer, H., Poussin, C., Farmer, P., Falquet, L., Burcelin, R., Delorenzi, M., Thorens, B.: Transcript profiling suggests that differential metabolic adaptation of mice to a high fat diet is associated with changes in liver to muscle lipid fluxes. J Biol Chem 2004, 279:50743-53. URL

    Dauvilliers, Y., Maret, S., Bassetti, C., Carlander, B., Billiard, M., Touchon, J., Tafti, M.: A monozygotic twin pair discordant for narcolepsy and CSF hypocretin-1. Neurology 2004, 62:2137-8. URL

    Dauvilliers, Y., Franken, P., Tafti, M.: Genetic regulation of sleep In Sleep: Circuits and Function Edited by Luppi CRC Press; 2004: 123-44.

    Dauvilliers, Y., Carlander, B., Rivier, F., Touchon, J., Tafti, M.: Successful management of cataplexy with intravenous immunoglobulins at narcolepsy onset. Ann Neurol 2004, 56:905-8. URL

    Dauvilliers, Y., Blouin, J. L., Neidhart, E., Carlander, B., Eliaou, J. F., Antonarakis, S. E., Billiard, M., Tafti, M.: A narcolepsy susceptibility locus maps to a 5 Mb region of chromosome 21q. Ann Neurol 2004, 56:382-8. URL

    Cook, S., Hugli, O., Egli, M., Menard, B., Thalmann, S., Sartori, C., Perrin, C., Nicod, P., Thorens, B., Vollenweider, P., Scherrer, U., Burcelin, R.: Partial gene deletion of endothelial nitric oxide synthase predisposes to exaggerated high-fat diet-induced insulin resistance and arterial hypertension. Diabetes 2004, 53:2067-72. URL

    Chen, M., Chory, J., Fankhauser, C.: Light signal transduction in higher plants. Annu Rev Genet 2004, 38:87-117. URL

    Casal, J. J., Fankhauser, C., Coupland, G., Blazquez, M. A.: Signalling for developmental plasticity. Trends Plant Sci 2004, 9:309-14. URL

    Burki, F., Kaessmann, H.: Birth and adaptive evolution of a hominoid gene that supports high neurotransmitter flux. Nat Genet 2004, 36:1061-3. URL

    Burcelin, R., Uldry, M., Foretz, M., Perrin, C., Dacosta, A., Nenniger-Tosato, M., Seydoux, J., Cotecchia, S., Thorens, B.: Impaired glucose homeostasis in mice lacking the alpha1b-adrenergic receptor subtype. J Biol Chem 2004, 279:1108-15. URL

    Betran, E., Emerson, J. J., Kaessmann, H., Long, M.: Sex chromosomes and male functions: where do new genes go?. Cell Cycle 2004, 3:873-5. URL

    Bariola, P. A., Retelska, D., Stasiak, A., Kammerer, R. A., Fleming, A., Hijri, M., Frank, S., Farmer, E. E.: Remorins form a novel family of coiled coil-forming oligomeric and filamentous proteins associated with apical, vascular and embryonic tissues in plants. Plant Mol Biol 2004, 55:579-94. URL

    Auwerx, J., Avner, P., Baldock, R., Ballabio, A., Balling, R., Barbacid, M., Berns, A., Bradley, A., Brown, S., Carmeliet, P., Chambon, P., Cox, R., Davidson, D., Davies, K., Duboule, D., Forejt, J., Granucci, F., Hastie, N., de Angelis, M. H., Jackson, I., Kioussis, D., Kollias, G., Lathrop, M., Lendahl, U., Malumbres, M., von Melchner, H., Muller, W., Partanen, J., Ricciardi-Castagnoli, P., Rigby, P., Rosen, B., Rosenthal, N., Skarnes, B., Stewart, A. F., Thornton, J., Tocchini-Valentini, G., Wagner, E., Wahli, W., Wurst, W.: The European dimension for the mouse genome mutagenesis program. Nat Genet 2004, 36:925-7. URL

    Arluison, M., Quignon, M., Thorens, B., Leloup, C., Penicaud, L.: Immunocytochemical localization of the glucose transporter 2 (GLUT2) in the adult rat brain. II. Electron microscopic study. J Chem Neuroanat 2004, 28:137-46. URL

    Arluison, M., Quignon, M., Nguyen, P., Thorens, B., Leloup, C., Penicaud, L.: Distribution and anatomical localization of the glucose transporter 2 (GLUT2) in the adult rat brain--an immunohistochemical study. J Chem Neuroanat 2004, 28:117-36. URL

    Antonarakis, S. E., Lyle, R., Dermitzakis, E. T., Reymond, A., Deutsch, S.: Chromosome 21 and down syndrome: from genomics to pathophysiology. Nat Rev Genet 2004, 5:725-38. URL


2003

 

 
    Zhao, X., Schramm, L., Hernandez, N., Herr, W.: A shared surface of TBP directs RNA polymerase II and III transcription via association with different TFIIB family members. Mol Cell 2003, 11:151-61. URL

    Zhao, X., Herr, W.: Role of the inhibitory DNA-binding surface of human TATA-binding protein in recruitment of human TFIIB family members. Mol Cell Biol 2003, 23:8152-60. URL

    Wysocka, J., Myers, M. P., Laherty, C. D., Eisenman, R. N., Herr, W.: Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1. Genes Dev 2003, 17:896-911. URL

    Wysocka, J., Herr, W.: The herpes simplex virus VP16-induced complex: the makings of a regulatory switch. Trends Biochem Sci 2003, 28:294-304. URL

    Thorens, B.: A gene knockout approach in mice to identify glucose sensors controlling glucose homeostasis. Pflugers Arch 2003, 445:482-90. URL

    Thorens, B.: [Gluco-incretin hormones in insulin secretion and diabetes]. Med Sci (Paris) 2003, 19:860-3. URL

    Tapparel, C., Reymond, A., Girardet, C., Guillou, L., Lyle, R., Lamon, C., Hutter, P., Antonarakis, S. E.: The TPTE gene family: cellular expression, subcellular localization and alternative splicing. Gene 2003, 323:189-99. URL

    Tan, N. S., Michalik, L., Desvergne, B., Wahli, W.: Peroxisome proliferator-activated receptor (PPAR)-beta as a target for wound healing drugs: what is possible?. Am J Clin Dermatol 2003, 4:523-30. URL

    Tafti, M., Petit, B., Chollet, D., Neidhart, E., de Bilbao, F., Kiss, J. Z., Wood, P. A., Franken, P.: Deficiency in short-chain fatty acid beta-oxidation affects theta oscillations during sleep. Nat Genet 2003, 34:320-5. URL

    Tafti, M., Dauvilliers, Y.: Pharmacogenomics in the treatment of narcolepsy. Pharmacogenomics 2003, 4:23-33. URL

    Tafti, M.: Immunogenetics and sleep disorders. Pharmacogenomics 2003, 4:365-7. URL

    Stasiak, A.: Topoisomerases In Encyclopedia of the Human Genome Edited by Cooper, David N. ; Nature Publishing Group; 2003:

    Stasiak, A.: DNA's golden jubilee. (Review of the book : "50 years of DNA", Palgrave Macmillan, UK). EMBO reports 2003, 4:1025-1026.

    Stasiak, A.: Life cycle of a biologist. (Review of the book : "Lives of a biologist: Adventures in a century of extraordinary science", by J.T. Bonner, Harvard University Press, Cambridge, USA). EMBO reports 2003, 4:457.

    Stasiak, A.: A knotty story. (Review of the book : Knots: Mathematics with a twist, by A. Sossinsky, Harvard University Press). Nature 2003, 421:479.

    Stasiak, A.: The first DNA. (Review of the book : "Rosalind Franklin: The dark lady of DNA", by B. Maddox, HarperCollins, New-York, USA). EMBO reports 2003, 4:14.

    Staiger, D., Allenbach, L., Salathia, N., Fiechter, V., Davis, S. J., Millar, A. J., Chory, J., Fankhauser, C.: The Arabidopsis SRR1 gene mediates phyB signaling and is required for normal circadian clock function. Genes Dev 2003, 17:256-68. URL

    Shaw, P. J., Franken, P.: Perchance to dream: solving the mystery of sleep through genetic analysis. J Neurobiol 2003, 54:179-202. URL

    Pessler, F., Hernandez, N.: Flexible DNA binding of the BTB/POZ-domain protein FBI-1. J Biol Chem 2003, 278:29327-35. URL

    Nikulina, M. A., Sandhu, N., Shamim, Z., Andersen, N. A., Oberson, A., Dupraz, P., Thorens, B., Karlsen, A. E., Bonny, C., Mandrup-Poulsen, T.: The JNK binding domain of islet-brain 1 inhibits IL-1 induced JNK activity and apoptosis but not the transcription of key proapoptotic or protective genes in insulin-secreting cell lines. Cytokine 2003, 24:13-24. URL

    Michalik, L., Tan, N. S., Wahli, W., Desvergne, B.: PPARs: nuclear receptors involved in the control of inflammation In Cellular proteins and their fatty acids in health and disease Volume Chapter 24. Edited by Duttaroy, AK , Spener, F; Weinheim: Wiley VCH; 2003: 419-435.

    Michalik, L., Desvergne, B., Wahli, W.: Peroxisome proliferator-activated receptors beta/delta: emerging roles for a previously neglected third family member. Curr Opin Lipidol 2003, 14:129-35. URL

    Mayo, K. E., Miller, L. J., Bataille, D., Dalle, S., Goke, B., Thorens, B., Drucker, D. J.: International Union of Pharmacology. XXXV. The glucagon receptor family. Pharmacol Rev 2003, 55:167-94. URL

    Lecendreux, M., Maret, S., Bassetti, C., Mouren, M. C., Tafti, M.: Clinical efficacy of high-dose intravenous immunoglobulins near the onset of narcolepsy in a 10-year-old boy. J Sleep Res 2003, 12:347-8. URL

    Lecendreux, M., Bassetti, C., Dauvilliers, Y., Mayer, G., Neidhart, E., Tafti, M.: HLA and genetic susceptibility to sleepwalking. Mol Psychiatry 2003, 8:114-7. URL

    Lariguet, P., Boccalandro, H. E., Alonso, J. M., Ecker, J. R., Chory, J., Casal, J. J., Fankhauser, C.: A growth regulatory loop that provides homeostasis to phytochrome a signaling. Plant Cell 2003, 15:2966-78. URL

    Kaessmann, H.: Human and chimpanzee nucleotide diversity. In Encyclopedia of the human genome. Edited by Cooper, David N. ; Nature Publishing Group; 2003:

    Julien, E., Herr, W.: Proteolytic processing is necessary to separate and ensure proper cell growth and cytokinesis functions of HCF-1. Embo J 2003, 22:2360-9. URL

    Jalouli, M., Carlsson, L., Ameen, C., Linden, D., Ljungberg, A., Michalik, L., Eden, S., Wahli, W., Oscarsson, J.: Sex difference in hepatic peroxisome proliferator-activated receptor alpha expression: influence of pituitary and gonadal hormones. Endocrinology 2003, 144:101-9. URL

    Jackson, L., Wahli, W., Michalik, L., Watson, S. A., Morris, T., Anderton, K., Bell, D. R., Smith, J. A., Hawkey, C. J., Bennett, A. J.: Potential role for peroxisome proliferator activated receptor (PPAR) in preventing colon cancer. Gut 2003, 52:1317-22. URL

    Hu, P., Wu, S., Hernandez, N.: A minimal RNA polymerase III transcription system from human cells reveals positive and negative regulatory roles for CK2. Mol Cell 2003, 12:699-709. URL

    Hellemans, K., Rombouts, K., Quartier, E., Dittie, A. S., Knorr, A., Michalik, L., Rogiers, V., Schuit, F., Wahli, W., Geerts, A.: PPARbeta regulates vitamin A metabolism-related gene expression in hepatic stellate cells undergoing activation. J Lipid Res 2003, 44:280-95. URL

    Hellemans, K., Michalik, L., Dittie, A., Knorr, A., Rombouts, K., De Jong, J., Heirman, C., Quartier, E., Schuit, F., Wahli, W., Geerts, A.: Peroxisome proliferator-activated receptor-beta signaling contributes to enhanced proliferation of hepatic stellate cells. Gastroenterology 2003, 124:184-201. URL

    Halliday, K.J., Fankhauser, C. : Phytochrome-hormonal signalling networks. New Phytologist 2003, 157:449-463. URL

    Haefliger, J. A., Tawadros, T., Meylan, L., Gurun, S. L., Roehrich, M. E., Martin, D., Thorens, B., Waeber, G.: The scaffold protein IB1/JIP-1 is a critical mediator of cytokine-induced apoptosis in pancreatic beta cells. J Cell Sci 2003, 116:1463-9. URL

    Guigo, R., Dermitzakis, E. T., Agarwal, P., Ponting, C. P., Parra, G., Reymond, A., Abril, J. F., Keibler, E., Lyle, R., Ucla, C., Antonarakis, S. E., Brent, M. R.: Comparison of mouse and human genomes followed by experimental verification yields an estimated 1,019 additional genes. Proc Natl Acad Sci U S A 2003, 100:1140-5. URL

    Gouyon, F., Caillaud, L., Carriere, V., Klein, C., Dalet, V., Citadelle, D., Kellett, G. L., Thorens, B., Leturque, A., Brot-Laroche, E.: Simple-sugar meals target GLUT2 at enterocyte apical membranes to improve sugar absorption: a study in GLUT2-null mice. J Physiol 2003, 552:823-32. URL

    Gatfield, D., Unterholzner, L., Ciccarelli, F. D., Bork, P., Izaurralde, E.: Nonsense-mediated mRNA decay in Drosophila: at the intersection of the yeast and mammalian pathways. EMBO J 2003, 22:3960-70. URL

    Galbiati, F., Polastri, L., Thorens, B., Dupraz, P., Fiorina, P., Cavallaro, U., Christofori, G., Davalli, A. M.: Molecular pathways involved in the antineoplastic effects of calcitriol on insulinoma cells. Endocrinology 2003, 144:1832-41. URL

    Friedli, M., Guipponi, M., Bertrand, S., Bertrand, D., Neerman-Arbez, M., Scott, H. S., Antonarakis, S. E., Reymond, A.: Identification of a novel member of the CLIC family, CLIC6, mapping to 21q22.12. Gene 2003, 320:31-40. URL

    Fribourg, S., Gatfield, D., Izaurralde, E., Conti, E.: A novel mode of RBD-protein recognition in the Y14-Mago complex. Nat Struct Biol 2003, 10:433-9. URL

    Franken, P., Tafti, M.: Genetics of sleep and sleep disorders. Front Biosci 2003, 8:e381-97. URL

    Duek, P. D., Fankhauser, C.: HFR1, a putative bHLH transcription factor, mediates both phytochrome A and cryptochrome signalling. Plant J 2003, 34:827-36. URL

    Doerflinger, H., Benton, R., Shulman, J. M., St Johnston, D.: The role of PAR-1 in regulating the polarised microtubule cytoskeleton in the Drosophila follicular epithelium. Development 2003, 130:3965-75. URL

    Dobay, A., Dubochet, J., Millett, K., Sottas, P. E., Stasiak, A.: Scaling behavior of random knots. Proc Natl Acad Sci U S A 2003, 100:5611-5615. URL

    Diao, Y., Dobay, A., Kusner, R.B., Millet, K., Stasiak, A.: The average crossing number of equilateral random polygons. Journal Physics A: Mathematical and General 2003, 36:11561-11574.

    Di-Poi, N., Michalik, L., Tan, N. S., Desvergne, B., Wahli, W.: The anti-apoptotic role of PPARbeta contributes to efficient skin wound healing. J Steroid Biochem Mol Biol 2003, 85:257-65. URL

    Dermitzakis, E. T., Reymond, A., Scamuffa, N., Ucla, C., Kirkness, E., Rossier, C., Antonarakis, S. E.: Evolutionary discrimination of mammalian conserved non-genic sequences (CNGs). Science 2003, 302:1033-5. URL

    Dauvilliers, Y., Carlander, B., Molinari, N., Desautels, A., Okun, M., Tafti, M., Montplaisir, J., Mignot, E., Billiard, M.: Month of birth as a risk factor for narcolepsy. Sleep 2003, 26:663-5. URL

    Dauvilliers, Y., Baumann, C. R., Carlander, B., Bischof, M., Blatter, T., Lecendreux, M., Maly, F., Besset, A., Touchon, J., Billiard, M., Tafti, M., Bassetti, C. L.: CSF hypocretin-1 levels in narcolepsy, Kleine-Levin syndrome, and other hypersomnias and neurological conditions. J Neurol Neurosurg Psychiatry 2003, 74:1667-73. URL

    Cook, S., Hugli, O., Egli, M., Vollenweider, P., Burcelin, R., Nicod, P., Thorens, B., Scherrer, U.: Clustering of cardiovascular risk factors mimicking the human metabolic syndrome X in eNOS null mice. Swiss Med Wkly 2003, 133:360-3. URL

    Cerf, C., Stasiak, A.: Quantized linear behavior of the writhe versus the number crossings in rational knots and links. New Journal of Physics 2003, 5:

    Cattan, P., Rottembourg, D., Cottet, S., Tardivel, I., Dupraz, P., Thorens, B., Boitard, C., Carel, J. C.: Destruction of conditional insulinoma cell lines in NOD mice: a role for autoimmunity. Diabetologia 2003, 46:504-10. URL

    Burcelin, R., Thorens, B., Glauser, M., Gaillard, R. C., Pralong, F. P.: Gonadotropin-releasing hormone secretion from hypothalamic neurons: stimulation by insulin and potentiation by leptin. Endocrinology 2003, 144:4484-91. URL

    Burcelin, R., Crivelli, V., Perrin, C., Da Costa, A., Mu, J., Kahn, B. B., Birnbaum, M. J., Kahn, C. R., Vollenweider, P., Thorens, B.: GLUT4, AMP kinase, but not the insulin receptor, are required for hepatoportal glucose sensor-stimulated muscle glucose utilization. J Clin Invest 2003, 111:1555-62. URL

    Benton, R., St Johnston, D.: Drosophila PAR-1 and 14-3-3 inhibit Bazooka/PAR-3 to establish complementary cortical domains in polarized cells. Cell 2003, 115:691-704. URL

    Benton, R., St Johnston, D.: A conserved oligomerization domain in drosophila Bazooka/PAR-3 is important for apical localization and epithelial polarity. Curr Biol 2003, 13:1330-4. URL

    Antonarakis, S. E., Reymond, A., Lyle, R., Deutsch, S., Dermitzakis, E. T.: Chromosome 21 and Down syndrome: the post-sequence era. Cold Spring Harb Symp Quant Biol 2003, 68:425-30. URL


2002

 

 
    Zhao, X., Herr, W.: A regulated two-step mechanism of TBP binding to DNA: a solvent-exposed surface of TBP inhibits TATA box recognition. Cell 2002, 108:615-27. URL

    Wahli, W.: Peroxisome proliferator-activated receptors (PPARs): from metabolic control to epidermal wound healing. Swiss Med Wkly 2002, 132:83-91. URL

    Uldry, M., Ibberson, M., Hosokawa, M., Thorens, B.: GLUT2 is a high affinity glucosamine transporter. FEBS Lett 2002, 524:199-203. URL

    Tan, N. S., Shaw, N. S., Vinckenbosch, N., Liu, P., Yasmin, R., Desvergne, B., Wahli, W., Noy, N.: Selective cooperation between fatty acid binding proteins and peroxisome proliferator-activated receptors in regulating transcription. Mol Cell Biol 2002, 22:5114-27. URL

    Tafti, M., Franken, P.: Invited review: genetic dissection of sleep. J Appl Physiol 2002, 92:1339-47. URL

    Stasiak, A., Dubochet, J.: Mathematics and physics of DNA knots In Où en sont les mathématiques Edited by Kantor, J-M.; Paris: Société Mathématique de France: 342-347; 2002:

    Stasiak, A.: Summary and review of the paper : A new algorithm for computing similarity between RNA structures . Mathematical Reviews 2002, 2002:92012.

    Stasiak, A.: Lucky experiment. (Review of the book : "Meselson, Stahl and the replication of DNA", by F. Lawrence Holmes, Yale University Press, New Haven, CT, USA). EMBO reports 2002, 3:925-926.

    Stasiak, A.: Nature's shapes (Review of the book : "What shape is a snowflake?", by I.S. Weidenfeld & Nicholson, London, UK). EMBO reports 2002, 3:822.

    Stasiak, A.: Lucky Jim. (Review of the book : "Genes, Girls and Gamow", by James D. Watson, Oxford University Press, Oxford, UK). EMBO reports 2002, 3:305.

    Schrenk, F., Brommage, G., Kaessmann, H.: Die Frühzeit des Menschen: Zurück zu den Wurzeln. Biologie in unserer Zeit 2002, 32:352-359. URL

    Schramm, L., Hernandez, N.: Recruitment of RNA polymerase III to its target promoters. Genes Dev 2002, 16:2593-620. URL

    Rodondi, N., Darioli, R., Ramelet, A. A., Hohl, D., Lenain, V., Perdrix, J., Wietlisbach, V., Riesen, W. F., Walther, T., Medinger, L., Nicod, P., Desvergne, B., Mooser, V.: High risk for hyperlipidemia and the metabolic syndrome after an episode of hypertriglyceridemia during 13-cis retinoic acid therapy for acne: a pharmacogenetic study. Ann Intern Med 2002, 136:582-9. URL

    Rieusset, J., Touri, F., Michalik, L., Escher, P., Desvergne, B., Niesor, E., Wahli, W.: A new selective peroxisome proliferator-activated receptor gamma antagonist with antiobesity and antidiabetic activity. Mol Endocrinol 2002, 16:2628-44. URL

    Reymond, A., Marigo, V., Yaylaoglu, M. B., Leoni, A., Ucla, C., Scamuffa, N., Caccioppoli, C., Dermitzakis, E. T., Lyle, R., Banfi, S., Eichele, G., Antonarakis, S. E., Ballabio, A.: Human chromosome 21 gene expression atlas in the mouse. Nature 2002, 420:582-6. URL

    Reymond, A., Camargo, A. A., Deutsch, S., Stevenson, B. J., Parmigiani, R. B., Ucla, C., Bettoni, F., Rossier, C., Lyle, R., Guipponi, M., de Souza, S., Iseli, C., Jongeneel, C. V., Bucher, P., Simpson, A. J., Antonarakis, S. E.: Nineteen additional unpredicted transcripts from human chromosome 21. Genomics 2002, 79:824-32. URL

    Reilly, P. T., Wysocka, J., Herr, W.: Inactivation of the retinoblastoma protein family can bypass the HCF-1 defect in tsBN67 cell proliferation and cytokinesis. Mol Cell Biol 2002, 22:6767-78. URL

    Reilly, P. T., Herr, W.: Spontaneous reversion of tsBN67 cell proliferation and cytokinesis defects in the absence of HCF-1 function. Exp Cell Res 2002, 277:119-30. URL

    Pericin, M., Althage, A., Freigang, S., Hengartner, H., Rolland, E., Dupraz, P., Thorens, B., Aebischer, P., Zinkernagel, R. M.: Allogeneic beta-islet cells correct diabetes and resist immune rejection. Proc Natl Acad Sci U S A 2002, 99:8203-6. URL

    Pendergrast, P. S., Wang, C., Hernandez, N., Huang, S.: FBI-1 can stimulate HIV-1 Tat activity and is targeted to a novel subnuclear domain that includes the Tat-P-TEFb-containing nuclear speckles. Mol Biol Cell 2002, 13:915-29. URL

    Olavarrieta, L., Martinez-Robles, M. L., Sogo, J. M., Stasiak, A., Hernandez, P., Krimer, D. B., Schvartzman, J. B.: Supercoiling, knotting and replication fork reversal in partially replicated plasmids. Nucleic Acids Res 2002, 30:656-66. URL

    Mouse_Genome_Sequencing_Consortium, with: , Reymond, A.: Initial sequencing and comparative analysis of the mouse genome. Nature 2002, 420:520-62. URL

    Michalik, L., Desvergne, B., Dreyer, C., Gavillet, M., Laurini, R. N., Wahli, W.: PPAR expression and function during vertebrate development. Int J Dev Biol 2002, 46:105-14. URL

    Merla, G., Ucla, C., Guipponi, M., Reymond, A.: Identification of additional transcripts in the Williams-Beuren syndrome critical region. Hum Genet 2002, 110:429-38. URL

    Ma, B., Hernandez, N.: Redundant cooperative interactions for assembly of a human U6 transcription initiation complex. Mol Cell Biol 2002, 22:8067-78. URL

    Kersten, S., Desvergne, B., Wahli, W.: Peroxisome Proliferator Activated Receptor alpha coordinates intermediary metabolism during fasting In PPARs : fom basic science to clinical applications Volume 18. Edited by J-C Fruchart, A-M Gotto , R Paoletti, B Staels; Dordrecht, Boston, London: Kluwers Academic Publishers; 2002: 1-4.

    Kaessmann*, H., Zollner*, S., Gustafsson, A. C., Wiebe, V., Laan, M., Lundeberg, J., Uhlen, M., Paabo, S.: Extensive linkage disequilibrium in small human populations in Eurasia. Am J Hum Genet 2002, 70:673-85. URL

    Kaessmann, H., Zollner, S., Nekrutenko, A., Li, W. H.: Signatures of domain shuffling in the human genome. Genome Res 2002, 12:1642-50. URL

    Kaessmann, H., Paabo, S.: The genetical history of humans and the great apes. J Intern Med 2002, 251:1-18. URL

    Joost, H. G., Bell, G. I., Best, J. D., Birnbaum, M. J., Charron, M. J., Chen, Y. T., Doege, H., James, D. E., Lodish, H. F., Moley, K. H., Moley, J. F., Mueckler, M., Rogers, S., Schurmann, A., Seino, S., Thorens, B.: Nomenclature of the GLUT/SLC2A family of sugar/polyol transport facilitators. Am J Physiol Endocrinol Metab 2002, 282:E974-6. URL

    Ibberson, M., Riederer, B. M., Uldry, M., Guhl, B., Roth, J., Thorens, B.: Immunolocalization of GLUTX1 in the testis and to specific brain areas and vasopressin-containing neurons. Endocrinology 2002, 143:276-84. URL

    Hu, P., Wu, S., Sun, Y., Yuan, C. C., Kobayashi, R., Myers, M. P., Hernandez, N.: Characterization of human RNA polymerase III identifies orthologues for Saccharomyces cerevisiae RNA polymerase III subunits. Mol Cell Biol 2002, 22:8044-55. URL

    Hosokawa, M., Thorens, B.: Glucose release from GLUT2-null hepatocytes: characterization of a major and a minor pathway. Am J Physiol Endocrinol Metab 2002, 282:E794-801. URL

    Hoidn, P., Kusner, R.B., Stasiak, A.: Quantization of energy and writhe in self-repelling knots. New Journal of Physics 2002, 4:20.1-20.11.

    Hihi, A. K., Michalik, L., Wahli, W.: PPARs: transcriptional effectors of fatty acids and their derivatives. Cell Mol Life Sci 2002, 59:790-8. URL

    Guissouma, H., Dupre, S. M., Becker, N., Jeannin, E., Seugnet, I., Desvergne, B., Demeneix, B. A.: Feedback on hypothalamic TRH transcription is dependent on thyroid hormone receptor N terminus. Mol Endocrinol 2002, 16:1652-66. URL

    Guipponi, M., Vuagniaux, G., Wattenhofer, M., Shibuya, K., Vazquez, M., Dougherty, L., Scamuffa, N., Guida, E., Okui, M., Rossier, C., Hancock, M., Buchet, K., Reymond, A., Hummler, E., Marzella, P. L., Kudoh, J., Shimizu, N., Scott, H. S., Antonarakis, S. E., Rossier, B. C.: The transmembrane serine protease (TMPRSS3) mutated in deafness DFNB8/10 activates the epithelial sodium channel (ENaC) in vitro. Hum Mol Genet 2002, 11:2829-36. URL

    Gatfield, D., Izaurralde, E.: REF1/Aly and the additional exon junction complex proteins are dispensable for nuclear mRNA export. J Cell Biol 2002, 159:579-88. URL

    Fauconnet, S., Lascombe, I., Chabannes, E., Adessi, G. L., Desvergne, B., Wahli, W., Bittard, H.: Differential regulation of vascular endothelial growth factor expression by peroxisome proliferator-activated receptors in bladder cancer cells. J Biol Chem 2002, 277:23534-43. URL

    Fankhauser, C., Staiger, D.: Photoreceptors in Arabidopsis thaliana: light perception, signal transduction and entrainment of the endogenous clock. Planta 2002, 216:1-16. URL

    Fankhauser, C.: Light perception in plants: cytokinins and red light join forces to keep phytochrome B active. Trends Plant Sci 2002, 7:143-5. URL

    Dobay, A., Sottas, P-E., Dubochet, J., Stasiak, A.: Putting random knots in order In Physical knots: knotting, linking and folding geometic objects in R3 Edited by Calvo, J.A., Millet, K., Rawdon, E.; Providence, Rhode Island: American Mathematical Society; 2002: 115-124.

    Dietler, G., Pieranski, P., Kasas, S., Stasiak, A.: The rupture of knotted strings under tension In Physical knots: knotting, linking and folding geometic objects in R3 Edited by Calvo, J.A., Millet, K., Rawdon, E.; Providence, Rhode Island: American Mathematical Society; 2002:

    Di-Poi, N., Tan, N. S., Michalik, L., Wahli, W., Desvergne, B.: Antiapoptotic role of PPARbeta in keratinocytes via transcriptional control of the Akt1 signaling pathway. Mol Cell 2002, 10:721-33. URL

    Desvergne, B., Michalik, L., Wahli, W.: Sensors for metabolic control : A regulatory network of nuclear receptors In Hormone signaling Edited by Goffin, V. , Kelly, P. A. ; Norwell: Kluwer Academic Publishers; 2002: 283-304.

    Dermitzakis, E. T., Reymond, A., Lyle, R., Scamuffa, N., Ucla, C., Deutsch, S., Stevenson, B. J., Flegel, V., Bucher, P., Jongeneel, C. V., Antonarakis, S. E.: Numerous potentially functional but non-genic conserved sequences on human chromosome 21. Nature 2002, 420:578-82. URL

    Dauvilliers, Y., Neidhart, E., Billiard, M., Tafti, M.: Sexual dimorphism of the catechol-O-methyltransferase gene in narcolepsy is associated with response to modafinil. Pharmacogenomics J 2002, 2:65-8. URL

    Dauvilliers, Y., Mayer, G., Lecendreux, M., Neidhart, E., Peraita-Adrados, R., Sonka, K., Billiard, M., Tafti, M.: Kleine-Levin syndrome: an autoimmune hypothesis based on clinical and genetic analyses. Neurology 2002, 59:1739-45. URL

    Cottet, S., Dupraz, P., Hamburger, F., Dolci, W., Jaquet, M., Thorens, B.: cFLIP protein prevents tumor necrosis factor-alpha-mediated induction of caspase-8-dependent apoptosis in insulin-secreting betaTc-Tet cells. Diabetes 2002, 51:1805-14. URL

    Ciana, P., Vegeto, E., Beato, M., Chambon, P., Gustafsson, J. A., Parker, M., Wahli, W., Maggi, A.: Looking at nuclear receptors from the heights of Erice. Workshop on nuclear receptor structure and function. EMBO Rep 2002, 3:125-9. URL

    Burcelin, R., Crivelli, V., Dacosta, A., Roy-Tirelli, A., Thorens, B.: Heterogeneous metabolic adaptation of C57BL/6J mice to high-fat diet. Am J Physiol Endocrinol Metab 2002, 282:E834-42. URL

    Bucka, A., Stasiak, A.: Construction and electrophoretic migration of single-stranded DNA knots and catenanes. Nucleic Acids Res 2002, 30:e24. URL

    Berti, C., Messali, S., Ballabio, A., Reymond, A., Meroni, G.: TRIM9 is specifically expressed in the embryonic and adult nervous system. Mech Dev 2002, 113:159-62. URL

    Benton, R., St Johnston, D.: Cell polarity: posterior Par-1 prevents proteolysis. Curr Biol 2002, 12:R479-81. URL

    Benton, R., Palacios, I. M., St Johnston, D.: Drosophila 14-3-3/PAR-5 is an essential mediator of PAR-1 function in axis formation. Dev Cell 2002, 3:659-71. URL

    Ayora, S., Weise, F., Mesa, P., Stasiak, A., Alonso, J. C.: Bacillus subtilis bacteriophage SPP1 hexameric DNA helicase, G40P, interacts with forked DNA. Nucleic Acids Res 2002, 30:2280-9. URL

    Aussel, L., Barre, F. X., Aroyo, M., Stasiak, A., Stasiak, A. Z., Sherratt, D.: FtsK Is a DNA motor protein that activates chromosome dimer resolution by switching the catalytic state of the XerC and XerD recombinases. Cell 2002, 108:195-205. URL

    Antonarakis, S. E., Lyle, R., Deutsch, S., Reymond, A.: Chromosome 21: a small land of fascinating disorders with unknown pathophysiology. Int J Dev Biol 2002, 46:89-96. URL


2001

 

 
    Zhao, Y., Christensen, S. K., Fankhauser, C., Cashman, J. R., Cohen, J. D., Weigel, D., Chory, J.: A role for flavin monooxygenase-like enzymes in auxin biosynthesis. Science 2001, 291:306-9. URL

    Zhao, X., Pendergrast, P. S., Hernandez, N.: A positioned nucleosome on the human U6 promoter allows recruitment of SNAPc by the Oct-1 POU domain. Mol Cell 2001, 7:539-49. URL

    Wysocka, J., Reilly, P. T., Herr, W.: Loss of HCF-1-chromatin association precedes temperature-induced growth arrest of tsBN67 cells. Mol Cell Biol 2001, 21:3820-9. URL

    Wysocka, J., Liu, Y., Kobayashi, R., Herr, W.: Developmental and cell-cycle regulation of Caenorhabditis elegans HCF phosphorylation. Biochemistry 2001, 40:5786-94. URL

    Van Dyck, E., Stasiak, A. Z., Stasiak, A., West, S. C.: Visualization of recombination intermediates produced by RAD52-mediated single-strand annealing. EMBO Rep 2001, 2:905-9. URL

    Uldry, M., Ibberson, M., Horisberger, J. D., Chatton, J. Y., Riederer, B. M., Thorens, B.: Identification of a mammalian H(+)-myo-inositol symporter expressed predominantly in the brain. Embo J 2001, 20:4467-77. URL

    Thorens, B., Dupraz, P., Cottet, S.: Engineering tolerance into transplanted beta cell lines. Ann N Y Acad Sci 2001, 944:267-70. URL

    Thorens, B.: GLUT2 in pancreatic and extra-pancreatic gluco-detection (review). Mol Membr Biol 2001, 18:265-73. URL

    Tan, N. S., Michalik, L., Noy, N., Yasmin, R., Pacot, C., Heim, M., Fluhmann, B., Desvergne, B., Wahli, W.: Critical roles of PPAR beta/delta in keratinocyte response to inflammation. Genes Dev 2001, 15:3263-77. URL

    Stumpel, F., Burcelin, R., Jungermann, K., Thorens, B.: Normal kinetics of intestinal glucose absorption in the absence of GLUT2: evidence for a transport pathway requiring glucose phosphorylation and transfer into the endoplasmic reticulum. Proc Natl Acad Sci U S A 2001, 98:11330-5. URL

    Stasiak, A.: Questioning the utility of RNA-DNA chimera in gene repair. Science STKE 2001,
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    Stasiak, A.: Crazy ideas ? (Review of the book : "Nine crazy ideas in Science: a few might even be true", by R. Ehrlich, Princeton University Press, New-Jersey). EMBO reports 2001, 2:978.

    Stasiak, A.: Pathological science. (Review of the book : The undergrowth of science: delusion, self-deception and human frailty, by W. Gratzer, Oxford University Press, Oxford, UK). EMBO Reports 2001, 2:762.

    Stasiak, A.: Broken symmetry. (Review of the book : Lucifer's legacy, the meaning of asymmetry, by F. Close, Oxford University Press, Oxford, UK). EMBO reports 2001, 2:562.

    Stasiak, A.: Rosalind Franklin. (Review of the book "Rosalind Franklin and DNA" by A. Sayre, W.W. Norton & Co, New-York). EMBO reports 2001, 2:181.

    Stasiak, A: Gene therapy. (Review of the book "The new healers", by William R. Clarck, Oxford University Press, Oxford, UK). EMBO reports 2001, 2:180.

    Roh, C., Roduit, R., Thorens, B., Fried, S., Kandror, K. V.: Lipoprotein lipase and leptin are accumulated in different secretory compartments in rat adipocytes. J Biol Chem 2001, 276:35990-4. URL

    Rodrigues, J. P., Rode, M., Gatfield, D., Blencowe, B. J., Carmo-Fonseca, M., Izaurralde, E.: REF proteins mediate the export of spliced and unspliced mRNAs from the nucleus. Proc Natl Acad Sci U S A 2001, 98:1030-5. URL

    Rieusset, J., Wahli, W., Desvergne, B.: Les récepteurs nucéaires PPARs (Peroxisome Proliferator Activated Receptors) : Trois isotypes pour de multiples fonctions. Médecine Thérapeutique Endocrinologie 2001, 3:4-12.

    Reymond, A., Meroni, G., Fantozzi, A., Merla, G., Cairo, S., Luzi, L., Riganelli, D., Zanaria, E., Messali, S., Cainarca, S., Guffanti, A., Minucci, S., Pelicci, P. G., Ballabio, A.: The tripartite motif family identifies cell compartments. Embo J 2001, 20:2140-51. URL

    Reymond, A., Friedli, M., Henrichsen, C. N., Chapot, F., Deutsch, S., Ucla, C., Rossier, C., Lyle, R., Guipponi, M., Antonarakis, S. E.: From PREDs and open reading frames to cDNA isolation: revisiting the human chromosome 21 transcription map. Genomics 2001, 78:46-54. URL

    Reuven, N. B., Arad, G., Stasiak, A. Z., Stasiak, A., Livneh, Z.: Lesion bypass by the Escherichia coli DNA polymerase V requires assembly of a RecA nucleoprotein filament. J Biol Chem 2001, 276:5511-7. URL

    Poirier, H., Niot, I., Monnot, M. C., Braissant, O., Meunier-Durmort, C., Costet, P., Pineau, T., Wahli, W., Willson, T. M., Besnard, P.: Differential involvement of peroxisome-proliferator-activated receptors alpha and delta in fibrate and fatty-acid-mediated inductions of the gene encoding liver fatty-acid-binding protein in the liver and the small intestine. Biochem J 2001, 355:481-8. URL

    Pieranski, P., Stasiak, A.: Gordian unknots. World of Science 2001, 114:6-9.

    Pieranski, P., Przybyl, S., Stasiak, A.: Tight open knots. European Physical Journal 2001, 6:123-128.

    Pieranski, P., Kasas, S., Dietler, G., Dubochet, J., Stasiak, A.: Localisation of breaking points in knotted strings. New Journal of Physics 2001, 3:10.1-10.3.

    Michalik, L., Desvergne, B., Tan, N. S., Basu-Modak, S., Escher, P., Rieusset, J., Peters, J. M., Kaya, G., Gonzalez, F. J., Zakany, J., Metzger, D., Chambon, P., Duboule, D., Wahli, W.: Impaired skin wound healing in peroxisome proliferator-activated receptor (PPAR)alpha and PPARbeta mutant mice. J Cell Biol 2001, 154:799-814. URL

    McIlwraith, M. J., Hall, D. R., Stasiak, A. Z., Stasiak, A., Wigley, D. B., West, S. C.: RadA protein from Archaeoglobus fulgidus forms rings, nucleoprotein filaments and catalyses homologous recombination. Nucleic Acids Res 2001, 29:4509-17. URL

    Masson, J. Y., Tarsounas, M. C., Stasiak, A. Z., Stasiak, A., Shah, R., McIlwraith, M. J., Benson, F. E., West, S. C.: Identification and purification of two distinct complexes containing the five RAD51 paralogs. Genes Dev 2001, 15:3296-307. URL

    Masson, J. Y., Stasiak, A. Z., Stasiak, A., Benson, F. E., West, S. C.: Complex formation by the human RAD51C and XRCC3 recombination repair proteins. Proc Natl Acad Sci U S A 2001, 98:8440-6. URL

    Ma, B., Hernandez, N.: A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc. J Biol Chem 2001, 276:5027-35. URL

    Liu, X. L., Covington, M. F., Fankhauser, C., Chory, J., Wagner, D. R.: ELF3 encodes a circadian clock-regulated nuclear protein that functions in an Arabidopsis PHYB signal transduction pathway. Plant Cell 2001, 13:1293-304. URL

    Lee, S., Herr, W.: Stabilization but not the transcriptional activity of herpes simplex virus VP16-induced complexes is evolutionarily conserved among HCF family members. J Virol 2001, 75:12402-11. URL

    Le Hir, H., Gatfield, D., Izaurralde, E., Moore, M. J.: The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay. EMBO J 2001, 20:4987-97. URL

    Le Hir, H., Gatfield, D., Braun, I. C., Forler, D., Izaurralde, E.: The protein Mago provides a link between splicing and mRNA localization. EMBO Rep 2001, 2:1119-24. URL

    Komar, C. M., Braissant, O., Wahli, W., Curry, T. E., Jr.: Expression and localization of PPARs in the rat ovary during follicular development and the periovulatory period. Endocrinology 2001, 142:4831-8. URL

    Kersten, S., Mandard, S., Escher, P., Gonzalez, F. J., Tafuri, S., Desvergne, B., Wahli, W.: The peroxisome proliferator-activated receptor alpha regulates amino acid metabolism. Faseb J 2001, 15:1971-8. URL

    Kaessmann, H., Wiebe, V., Weiss, G., Paabo, S.: Great ape DNA sequences reveal a reduced diversity and an expansion in humans. Nat Genet 2001, 27:155-6. URL

    Joost, H. G., Thorens, B.: The extended GLUT-family of sugar/polyol transport facilitators: nomenclature, sequence characteristics, and potential function of its novel members (review). Mol Membr Biol 2001, 18:247-56. URL

    Huynh, J. R., Shulman, J. M., Benton, R., St Johnston, D.: PAR-1 is required for the maintenance of oocyte fate in Drosophila. Development 2001, 128:1201-9. URL

    Hosokawa, M., Dolci, W., Thorens, B.: Differential sensitivity of GLUT1- and GLUT2-expressing beta cells to streptozotocin. Biochem Biophys Res Commun 2001, 289:1114-7. URL

    Holtz, J., Uldry, C., Thorens, B.: [Isocyanate-induced alveolitis in a furniture manufacture worker]. Rev Mal Respir 2001, 18:429-31. URL

    Hernandez, N.: Small nuclear RNA genes: a model system to study fundamental mechanisms of transcription. J Biol Chem 2001, 276:26733-6. URL

    Guipponi, M., Tapparel, C., Jousson, O., Scamuffa, N., Mas, C., Rossier, C., Hutter, P., Meda, P., Lyle, R., Reymond, A., Antonarakis, S. E.: The murine orthologue of the Golgi-localized TPTE protein provides clues to the evolutionary history of the human TPTE gene family. Hum Genet 2001, 109:569-75. URL

    Gatfield, D., Le Hir, H., Schmitt, C., Braun, I. C., Kocher, T., Wilm, M., Izaurralde, E.: The DExH/D box protein HEL/UAP56 is essential for mRNA nuclear export in Drosophila. Curr Biol 2001, 11:1716-21. URL

    Franken, P., Chollet, D., Tafti, M.: The homeostatic regulation of sleep need is under genetic control. J Neurosci 2001, 21:2610-21. URL

    Forus, A., D'Angelo, A., Henriksen, J., Merla, G., Maelandsmo, G. M., Florenes, V. A., Olivieri, S., Bjerkehagen, B., Meza-Zepeda, L. A., del Vecchio Blanco, F., Muller, C., Sanvito, F., Kononen, J., Nesland, J. M., Fodstad, O., Reymond, A., Kallioniemi, O. P., Arrigoni, G., Ballabio, A., Myklebost, O., Zollo, M.: Amplification and overexpression of PRUNE in human sarcomas and breast carcinomas-a possible mechanism for altering the nm23-H1 activity. Oncogene 2001, 20:6881-90. URL

    Fankhauser, C. : The Genetics of Photomorphogenesis in Plants In The Encyclopaedia of Genetics Edited by S. Brenner (Academic Press); 2001: 1454-1458.

    Fankhauser, C.: The phytochromes, a family of red/far-red absorbing photoreceptors. J Biol Chem 2001, 276:11453-6. URL

    Escher, P., Braissant, O., Basu-Modak, S., Michalik, L., Wahli, W., Desvergne, B.: Rat PPARs: quantitative analysis in adult rat tissues and regulation in fasting and refeeding. Endocrinology 2001, 142:4195-202. URL

    Duplain, H., Burcelin, R., Sartori, C., Cook, S., Egli, M., Lepori, M., Vollenweider, P., Pedrazzini, T., Nicod, P., Thorens, B., Scherrer, U.: Insulin resistance, hyperlipidemia, and hypertension in mice lacking endothelial nitric oxide synthase. Circulation 2001, 104:342-5. URL

    Dobay, A., Sottas, P-E., Dubochet, J., Stasiak, A.: Predicting optimal length of random knots. Letters in Mathematical Physics 2001, 55:239-247.

    Desreumaux, P., Dubuquoy, L., Nutten, S., Peuchmaur, M., Englaro, W., Schoonjans, K., Derijard, B., Desvergne, B., Wahli, W., Chambon, P., Leibowitz, M. D., Colombel, J. F., Auwerx, J.: Attenuation of colon inflammation through activators of the retinoid X receptor (RXR)/peroxisome proliferator-activated receptor gamma (PPARgamma) heterodimer. A basis for new therapeutic strategies. J Exp Med 2001, 193:827-38. URL

    Davies, A. A., Masson, J. Y., McIlwraith, M. J., Stasiak, A. Z., Stasiak, A., Venkitaraman, A. R., West, S. C.: Role of BRCA2 in control of the RAD51 recombination and DNA repair protein. Mol Cell 2001, 7:273-82. URL

    Dauvilliers, Y., Tafti, M., Billiard, M.: [Genetics of human narcolepsy]. Rev Neurol (Paris) 2001, 157:S92-6. URL

    Dauvilliers, Y., Neidhart, E., Lecendreux, M., Billiard, M., Tafti, M.: MAO-A and COMT polymorphisms and gene effects in narcolepsy. Mol Psychiatry 2001, 6:367-72. URL

    Cottet, S., Dupraz, P., Hamburger, F., Dolci, W., Jaquet, M., Thorens, B.: SOCS-1 protein prevents Janus Kinase/STAT-dependent inhibition of beta cell insulin gene transcription and secretion in response to interferon-gamma. J Biol Chem 2001, 276:25862-70. URL

    Chong, S. S., Hu, P., Hernandez, N.: Reconstitution of transcription from the human U6 small nuclear RNA promoter with eight recombinant polypeptides and a partially purified RNA polymerase III complex. J Biol Chem 2001, 276:20727-34. URL

    Chollet, D., Franken, P., Raffin, Y., Henrotte, J. G., Widmer, J., Malafosse, A., Tafti, M.: Magnesium involvement in sleep: genetic and nutritional models. Behav Genet 2001, 31:413-25. URL

    Canaple, L., Nurdin, N., Angelova, N., Saugy, D., Hunkeler, D., Desvergne, B.: Maintenance of primary murine hepatocyte functions in multicomponent polymer capsules--in vitro cryopreservation studies. J Hepatol 2001, 34:11-8. URL

    Canaple, L., Nurdin, N., Angelova, N., Hunkeler, D., Desvergne, B.: Development of a coculture model of encapsulated cells. Ann N Y Acad Sci 2001, 944:350-61. URL

    Cairo, S., Merla, G., Urbinati, F., Ballabio, A., Reymond, A.: WBSCR14, a gene mapping to the Williams--Beuren syndrome deleted region, is a new member of the Mlx transcription factor network. Hum Mol Genet 2001, 10:617-27. URL

    Burcelin, R., Thorens, B.: Evidence that extrapancreatic GLUT2-dependent glucose sensors control glucagon secretion. Diabetes 2001, 50:1282-9. URL

    Burcelin, R., Da Costa, A., Drucker, D., Thorens, B.: Glucose competence of the hepatoportal vein sensor requires the presence of an activated glucagon-like peptide-1 receptor. Diabetes 2001, 50:1720-8. URL

    Bucka, A., Stasiak, A.: Commentary about the paper : Positive torsional strain causes the formation of a four-way junction at replication forks. CHEMTRACTS-Biochemistry and Molecular Biology 2001, 14:166-173.

    Bucka, A., Stasiak, A.: RecA-mediated strand exchange traverses substitutional heterologies more easily than deletions or insertions. Nucleic Acids Res 2001, 29:2464-70. URL

    Babb, R., Huang, C. C., Aufiero, D. J., Herr, W.: DNA recognition by the herpes simplex virus transactivator VP16: a novel DNA-binding structure. Mol Cell Biol 2001, 21:4700-12. URL


2000

 

 
    Wilson, A. C., Boutros, M., Johnson, K. M., Herr, W.: HCF-1 amino- and carboxy-terminal subunit association through two separate sets of interaction modules: involvement of fibronectin type 3 repeats. Mol Cell Biol 2000, 20:6721-30. URL

    Weigel, D., Ahn, J. H., Blazquez, M. A., Borevitz, J. O., Christensen, S. K., Fankhauser, C., Ferrandiz, C., Kardailsky, I., Malancharuvil, E. J., Neff, M. M., Nguyen, J. T., Sato, S., Wang, Z. Y., Xia, Y., Dixon, R. A., Harrison, M. J., Lamb, C. J., Yanofsky, M. F., Chory, J.: Activation tagging in Arabidopsis. Plant Physiol 2000, 122:1003-13. URL

    Utzig, S., Fankhauser, C., Simanis, V.: Periodic accumulation of cdc15 mRNA is not necessary for septation in Schizosaccharomyces pombe. J Mol Biol 2000, 302:751-9. URL

    Thorens, B., Guillam, M. T., Beermann, F., Burcelin, R., Jaquet, M.: Transgenic reexpression of GLUT1 or GLUT2 in pancreatic beta cells rescues GLUT2-null mice from early death and restores normal glucose-stimulated insulin secretion. J Biol Chem 2000, 275:23751-8. URL

    ten Heggeler-Bordier, B., Muller, S., Monestier, M., Wahli, W.: An immuno-electron microscopical analysis of transcribing multinucleosomal templates: what happens to the histones?. J Mol Biol 2000, 299:853-8. URL

    Stasiak, A. Z., Larquet, E., Stasiak, A., Muller, S., Engel, A., Van Dyck, E., West, S. C., Egelman, E. H.: The human Rad52 protein exists as a heptameric ring. Curr Biol 2000, 10:337-40. URL

    Stasiak, A., Maddocks, J. H.: Mathematics. Best packing in proteins and DNA. Nature 2000, 406:251-3. URL

    Stasiak, A.: Quantum-like properties of knots and links In Knots in Hellas Edited by Gordon, C. McA., Jones, V.F.R., Kauffman, L.H., Lambropolou, S. , Przytycki, J.H.; Singapore: World Scientific Publishing; 2000: 477-500.

    Stasiak, A.: DNA topology: feeling the pulse of a topoisomerase. Curr Biol 2000, 10:R526-8. URL

    Spiegelman, J. I., Mindrinos, M. N., Fankhauser, C., Richards, D., Lutes, J., Chory, J., Oefner, P. J.: Cloning of the Arabidopsis RSF1 gene by using a mapping strategy based on high-density DNA arrays and denaturing high-performance liquid chromatography. Plant Cell 2000, 12:2485-2498. URL

    Shulman, J. M., Benton, R., St Johnston, D.: The Drosophila homolog of C. elegans PAR-1 organizes the oocyte cytoskeleton and directs oskar mRNA localization to the posterior pole. Cell 2000, 101:377-88. URL

    Schramm, L., Pendergrast, P. S., Sun, Y., Hernandez, N.: Different human TFIIIB activities direct RNA polymerase III transcription from TATA-containing and TATA-less promoters. Genes Dev 2000, 14:2650-63. URL

    Robyr, D., Wolffe, A. P., Wahli, W.: Nuclear hormone receptor coregulators in action: diversity for shared tasks. Mol Endocrinol 2000, 14:329-47. URL

    Robyr, D., Gegonne, A., Wolffe, A. P., Wahli, W.: Determinants of vitellogenin B1 promoter architecture. HNF3 and estrogen responsive transcription within chromatin. J Biol Chem 2000, 275:28291-300. URL

    Pieranski, P., Stasiak, A.: Un noeud...peu gordien. Pour la Science 2000, 278:12.

    Pende, M., Kozma, S. C., Jaquet, M., Oorschot, V., Burcelin, R., Le Marchand-Brustel, Y., Klumperman, J., Thorens, B., Thomas, G.: Hypoinsulinaemia, glucose intolerance and diminished beta-cell size in S6K1-deficient mice. Nature 2000, 408:994-7. URL

    Nurdin, N., Canaple, L., Bartkowiak, A., Desvergne, B., Hunkeler, D.: Capsule permeability via polymer and protein ingress/egress. J. App. Polym. Sci. 2000, 75:1165-1175.

    Neff, M. M., Fankhauser, C., Chory, J.: Light: an indicator of time and place. Genes Dev 2000, 14:257-71. URL

    Michalik, L., Desvergne, B., Wahli, W.: Les bases moléculaires de l'obésité : vers de nouvelles thérapeutiques ?. Médecines Sciences 2000, 16:1030-1039.

    Michalik, L., Desvergne, B., Basu-Modak, S., Tan, N. S., Wahli, W.: Nuclear hormone receptors and mouse skin homeostasis: implication of PPARbeta. Horm Res 2000, 54:263-8. URL

    Meroni, G., Cairo, S., Merla, G., Messali, S., Brent, R., Ballabio, A., Reymond, A.: Mlx, a new Max-like bHLHZip family member: the center stage of a novel transcription factors regulatory pathway?. Oncogene 2000, 19:3266-77. URL

    McIlwraith, M. J., Van Dyck, E., Masson, J. Y., Stasiak, A. Z., Stasiak, A., West, S. C.: Reconstitution of the strand invasion step of double-strand break repair using human Rad51 Rad52 and RPA proteins. J Mol Biol 2000, 304:151-64. URL

    Lazennec, G., Canaple, L., Saugy, D., Wahli, W.: Activation of peroxisome proliferator-activated receptors (PPARs) by their ligands and protein kinase A activators. Mol Endocrinol 2000, 14:1962-75. URL

    Lascombe, I., Beffa, D., Ruegg, U., Tarradellas, J., Wahli, W.: Estrogenic activity assessment of environmental chemicals using in vitro assays: identification of two new estrogenic compounds. Environ Health Perspect 2000, 108:621-9. URL

    Kersten, S., Wahli, W.: Peroxisome proliferator activated receptor agonists In New approches to drug development Volume 89. Basel: Birkhaüser Publishers; 2000: 141-51.

    Kersten, S., Mandard, S., Tan, N. S., Escher, P., Metzger, D., Chambon, P., Gonzalez, F. J., Desvergne, B., Wahli, W.: Characterization of the fasting-induced adipose factor FIAF, a novel peroxisome proliferator-activated receptor target gene. J Biol Chem 2000, 275:28488-93. URL

    Kersten, S., Desvergne, B., Wahli, W.: Roles of PPARs in health and disease. Nature 2000, 405:421-4. URL

    Katritch, V., Olson, W. K., Vologodskii, A., Dubochet, J., Stasiak, A.: Tightness of random knotting. Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics 2000, 61:5545-9. URL

    Ingman, M., Kaessmann, H., Paabo, S., Gyllensten, U.: Mitochondrial genome variation and the origin of modern humans. Nature 2000, 408:708-13. URL

    Ibberson, M., Uldry, M., Thorens, B.: GLUTX1, a novel mammalian glucose transporter expressed in the central nervous system and insulin-sensitive tissues. J Biol Chem 2000, 275:4607-12. URL

    Guillam, M. T., Dupraz, P., Thorens, B.: Glucose uptake, utilization, and signaling in GLUT2-null islets. Diabetes 2000, 49:1485-91. URL

    Franken, P., Lopez-Molina, L., Marcacci, L., Schibler, U., Tafti, M.: The transcription factor DBP affects circadian sleep consolidation and rhythmic EEG activity. J Neurosci 2000, 20:617-25. URL

    Fankhauser, C., Chory, J.: RSF1, an Arabidopsis locus implicated in phytochrome A signaling. Plant Physiol 2000, 124:39-45. URL

    Fankhauser, C.: Phytochromes as light-modulated protein kinases. Semin Cell Dev Biol 2000, 11:467-73. URL

    Escher, P., Wahli, W.: Peroxisome proliferator-activated receptors: insight into multiple cellular functions. Mutat Res 2000, 448:121-38. URL

    Dupraz, P., Cottet, S., Hamburger, F., Dolci, W., Felley-Bosco, E., Thorens, B.: Dominant negative MyD88 proteins inhibit interleukin-1beta /interferon-gamma -mediated induction of nuclear factor kappa B-dependent nitrite production and apoptosis in beta cells. J Biol Chem 2000, 275:37672-8. URL

    Chollet, D., Franken, P., Raffin, Y., Malafosse, A., Widmer, J., Tafti, M.: Blood and brain magnesium in inbred mice and their correlation with sleep quality. Am J Physiol Regul Integr Comp Physiol 2000, 279:R2173-8. URL

    Cerf, C., Stasiak, A.: A topological invariant to predict the three-dimensional writhe of ideal configurations of knots and links. Proc Natl Acad Sci U S A 2000, 97:3795-8. URL

    Burcelin, R., Dolci, W., Thorens, B.: Portal glucose infusion in the mouse induces hypoglycemia: evidence that the hepatoportal glucose sensor stimulates glucose utilization. Diabetes 2000, 49:1635-42. URL

    Burcelin, R., Dolci, W., Thorens, B.: Glucose sensing by the hepatoportal sensor is GLUT2-dependent: in vivo analysis in GLUT2-null mice. Diabetes 2000, 49:1643-8. URL

    Burcelin, R., del Carmen Munoz, M., Guillam, M. T., Thorens, B.: Liver hyperplasia and paradoxical regulation of glycogen metabolism and glucose-sensitive gene expression in GLUT2-null hepatocytes. Further evidence for the existence of a membrane-based glucose release pathway. J Biol Chem 2000, 275:10930-6. URL

    Bucka, A., Stasiak, A.: Commentary about the paper : Tailed duplex DNA is the preferred substrate for Rad51 protein-mediated homologous pairing. CHEMTRACTS-Biochemistry and Molecular Biology 2000, 13:415-423.


1999

 

 
    Walker, K., Ketchum, R. E., Hezari, M., Gatfield, D., Goleniowski, M., Barthol, A., Croteau, R.: Partial purification and characterization of acetyl coenzyme A: taxa-4(20),11(12)-dien-5alpha-ol O-acetyl transferase that catalyzes the first acylation step of taxol biosynthesis. Arch Biochem Biophys 1999, 364:273-9. URL

    Wahli, W., Kersten, S., Devchand, P., Desvergne, B.: PPARα : cross-talk with membrane receptors and control of energy homeostasis In Common Diseases - Genetic and Pathogenic Aspects of Multifactorial Diseases Volume 1181. Edited by H. Imura, M Kasuga , K. Nakao; 1999: 159-167.

    Wahli, W., Devchand, P. R., IJpenberg, A., Desvergne, B.: Fatty acids, eicosanoids, and hypolipidemic agents regulate gene expression through direct binding to peroxisome proliferator-activated receptors. Adv Exp Med Biol 1999, 447:199-209. URL

    van Gool, A. J., Hajibagheri, N. M., Stasiak, A., West, S. C.: Assembly of the Escherichia coli RuvABC resolvasome directs the orientation of holliday junction resolution. Genes Dev 1999, 13:1861-70. URL

    Van Dyck, E., Stasiak, A. Z., Stasiak, A., West, S. C.: Binding of double-strand breaks in DNA by human Rad52 protein. Nature 1999, 398:728-31. URL

    Thorens, B., Ruegger, M.: [Work capacity in the cae of pulmonary diseases]. Schweiz Med Wochenschr 1999, 129:459-64. URL

    Tafti, M., Chollet, D., Valatx, J. L., Franken, P.: Quantitative trait loci approach to the genetics of sleep in recombinant inbred mice. J Sleep Res 1999, 8 Suppl 1:37-43. URL

    Stasiak, A., Dubochet, J., Furrer, P., Gonzalez, O., Maddocks, J.: DNA: uncooked, al dente, or scotti?. Science 1999, 283:1641. URL

    Stasiak, A., Dobay, A, Dubochet, J, Dietler, G. : Knotted fishing line, covalent bonds and breaking points. Technical comment. Science 1999, 286:11.

    Sottas, P. E., Larquet, E., Stasiak, A., Dubochet, J.: Brownian dynamics simulation of DNA condensation. Biophys J 1999, 77:1858-70. URL

    Sogo, J. M., Stasiak, A., Martinez-Robles, M. L., Krimer, D. B., Hernandez, P., Schvartzman, J. B.: Formation of knots in partially replicated DNA molecules. J Mol Biol 1999, 286:637-43. URL

    Schvartzam, J., Sogo, J., Stasiak, A.: Noeuds et ADN; les noeuds de l'ADN éclairent la réplication. Pour la Science 1999, 259:25-26.

    Schibler, U., Tafti, M.: Molecular approaches towards the isolation of sleep-related genes. J Sleep Res 1999, 8 Suppl 1:1-10. URL

    Reymond, A., Volorio, S., Merla, G., Al-Maghtheh, M., Zuffardi, O., Bulfone, A., Ballabio, A., Zollo, M.: Evidence for interaction between human PRUNE and nm23-H1 NDPKinase. Oncogene 1999, 18:7244-52. URL

    Morrison, D. J., Pendergrast, P. S., Stavropoulos, P., Colmenares, S. U., Kobayashi, R., Hernandez, N.: FBI-1, a factor that binds to the HIV-1 inducer of short transcripts (IST), is a POZ domain protein. Nucleic Acids Res 1999, 27:1251-62. URL

    Mittal, V., Ma, B., Hernandez, N.: SNAP(c): a core promoter factor with a built-in DNA-binding damper that is deactivated by the Oct-1 POU domain. Genes Dev 1999, 13:1807-21. URL

    Michalik, L., Wahli, W.: Peroxisome proliferator-activated receptors: three isotypes for a multitude of functions. Curr Opin Biotechnol 1999, 10:564-70. URL

    Mezard, C., George, H., Davies, A. A., van Gool, A. J., Zerbib, D., Stasiak, A., West, S. C.: Escherichia coli RuvBL268S: a mutant RuvB protein that exhibits wild-type activities in vitro but confers a UV-sensitive ruv phenotype in vivo. Nucleic Acids Res 1999, 27:1275-82. URL

    Masson, J. Y., Davies, A. A., Hajibagheri, N., Van Dyck, E., Benson, F. E., Stasiak, A. Z., Stasiak, A., West, S. C.: The meiosis-specific recombinase hDmc1 forms ring structures and interacts with hRad51. Embo J 1999, 18:6552-60. URL

    Liu, Y., Hengartner, M. O., Herr, W.: Selected elements of herpes simplex virus accessory factor HCF are highly conserved in Caenorhabditis elegans. Mol Cell Biol 1999, 19:909-15. URL

    Liu, Y., Gong, W., Huang, C. C., Herr, W., Cheng, X.: Crystal structure of the conserved core of the herpes simplex virus transcriptional regulatory protein VP16. Genes Dev 1999, 13:1692-703. URL

    Le Hellard, S., Neidhart, E., Thomas, P., Feingold, J., Malafosse, A., Tafti, M.: Lack of association between juvenile myoclonic epilepsy and HLA-DR13. Epilepsia 1999, 40:117-9. URL

    Kuhlman, T. C., Cho, H., Reinberg, D., Hernandez, N.: The general transcription factors IIA, IIB, IIF, and IIE are required for RNA polymerase II transcription from the human U1 small nuclear RNA promoter. Mol Cell Biol 1999, 19:2130-41. URL

    Kersten, S., Wahli, W.: Adopting orphans : finding ligands In Nuclear Receptors : A Practical Approach Edited by D. Picard; Oxford: Oxford University Press; 1999: 71-93.

    Kersten, S., Seydoux, J., Peters, J. M., Gonzalez, F. J., Desvergne, B., Wahli, W.: Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting. J Clin Invest 1999, 103:1489-98. URL

    Kaessmann, H., Wiebe, V., Paabo, S.: Extensive nuclear DNA sequence diversity among chimpanzees. Science 1999, 286:1159-62. URL

    Kaessmann, H., Heissig, F., von Haeseler, A., Paabo, S.: DNA sequence variation in a non-coding region of low recombination on the human X chromosome. Nat Genet 1999, 22:78-81. URL

    Hihi, A. K., Wahli, W.: Structure and function of the estrogen receptor In Estrogens and antiestrogens I. Handbook of Experimental Pharmacolog Volume 135/I. Edited by Springer Verlag; Heilderberg: 1999: 111-126.

    George, H., Mezard, C., Stasiak, A., West, S. C.: Helicase-defective RuvB(D113E) promotes RuvAB-mediated branch migration in vitro. J Mol Biol 1999, 293:505-19. URL

    Franken, P., Malafosse, A., Tafti, M.: Genetic determinants of sleep regulation in inbred mice. Sleep 1999, 22:155-69. URL

    Fankhauser, C., Yeh, K. C., Lagarias, J. C., Zhang, H., Elich, T. D., Chory, J.: PKS1, a substrate phosphorylated by phytochrome that modulates light signaling in Arabidopsis. Science 1999, 284:1539-41. URL

    Fankhauser, C., Chory, J.: Light receptor kinases in plants!. Curr Biol 1999, 9:R123-6. URL

    Dupraz, P., Rinsch, C., Pralong, W. F., Rolland, E., Zufferey, R., Trono, D., Thorens, B.: Lentivirus-mediated Bcl-2 expression in betaTC-tet cells improves resistance to hypoxia and cytokine-induced apoptosis while preserving in vitro and in vivo control of insulin secretion. Gene Ther 1999, 6:1160-9. URL

    Di Croce, L., Okret, S., Kersten, S., Gustafsson, J. A., Parker, M., Wahli, W., Beato, M.: Steroid and nuclear receptors. Villefranche-sur-Mer, France, May 25-27, 1999. Embo J 1999, 18:6201-10. URL

    Devchand, P. R., Ijpenberg, A., Devergne, B., Wahli, W.: PPARs: nuclear receptors for fatty acids, eicosanoids, and xenobiotics. Adv Exp Med Biol 1999, 469:231-6. URL

    Devchand, P. R., Hihi, A. K., Perroud, M., Schleuning, W. D., Spiegelman, B. M., Wahli, W.: Chemical probes that differentially modulate PPARalpha and BLTR, nuclear and cell surface receptors for leukotriene B(4). J Biol Chem 1999, 274:23341-8. URL

    Desvergne, B., Wahli, W.: Peroxisome proliferator-activated receptors: nuclear control of metabolism. Endocr Rev 1999, 20:649-88. URL

    Burcelin, R., Rolland, E., Dolci, W., Germain, S., Carrel, V., Thorens, B.: Encapsulated, genetically engineered cells, secreting glucagon-like peptide-1 for the treatment of non-insulin-dependent diabetes mellitus. Ann N Y Acad Sci 1999, 875:277-85. URL

    Burcelin, R., Dolci, W., Thorens, B.: Long-lasting antidiabetic effect of a dipeptidyl peptidase IV-resistant analog of glucagon-like peptide-1. Metabolism 1999, 48:252-8. URL

    Bernard, P., Goudonnet, H., Artur, Y., Desvergne, B., Wahli, W.: Activation of the mouse TATA-less and human TATA-containing UDP-glucuronosyltransferase 1A1 promoters by hepatocyte nuclear factor 1. Mol Pharmacol 1999, 56:526-36. URL

    Basu-Modak, S., Braissant, O., Escher, P., Desvergne, B., Honegger, P., Wahli, W.: Peroxisome proliferator-activated receptor beta regulates acyl-CoA synthetase 2 in reaggregated rat brain cell cultures. J Biol Chem 1999, 274:35881-8. URL

    Bartkowiak, A., Canaple, L., Ceausoglu, I., Nurdin, N., Renken, A., Rindisbacher, L., Wandrey, C., Desvergne, B., Hunkeler, D.: New multicomponent capsules for immunoisolation. Ann N Y Acad Sci 1999, 875:135-45. URL

    Ayora, S., Stasiak, A., Alonso, J. C.: The Bacillus subtilis bacteriophage SPP1 G39P delivers and activates the G40P DNA helicase upon interacting with the G38P-bound replication origin. J Mol Biol 1999, 288:71-85. URL


1998

 

 
    Wong, M. W., Henry, R. W., Ma, B., Kobayashi, R., Klages, N., Matthias, P., Strubin, M., Hernandez, N.: The large subunit of basal transcription factor SNAPc is a Myb domain protein that interacts with Oct-1. Mol Cell Biol 1998, 18:368-77. URL

    Wang, L., Voloshin, O. N., Stasiak, A., Camerini-Otero, R. D.: Homologous DNA pairing domain peptides of RecA protein: intrinsic propensity to form beta-structures and filaments. J Mol Biol 1998, 277:1-11. URL

    Vologodskii, A. V., Crisona, N. J., Laurie, B., Pieranski, P., Katritch, V., Dubochet, J., Stasiak, A.: Sedimentation and electrophoretic migration of DNA knots and catenanes. J Mol Biol 1998, 278:1-3. URL

    Vanier, M. T., Neuville, P., Michalik, L., Launay, J. F.: Expression of specific tau exons in normal and tumoral pancreatic acinar cells. J Cell Sci 1998, 111 ( Pt 10):1419-32. URL

    Van Dyck, E., Hajibagheri, N. M., Stasiak, A., West, S. C.: Visualisation of human rad52 protein and its complexes with hRad51 and DNA. J Mol Biol 1998, 284:1027-38. URL

    Tsai-Pflugfelder, M., Gasser, S. M., Wahli, W.: Functional interaction between the estrogen receptor and CTF1: analysis of the vitellogenin gene B1 promoter in yeast. Mol Endocrinol 1998, 12:1525-41. URL

    Stasiak, A., Katritch, V., Kauffman, L.H., Kaufman,L.H. : Ideal Knots. Knots and Everything 1998, 19:

    Stasiak, A., Dubochet, J., Katritch, V., Pieranski, P.: Ideal knots and their relation to the physics of real knots In Ideal knots Edited by A. Stasiak, V. Katritch, L.H. Haufman; Singapore: World Scientific Publishing; 1998: 1-19.

    Stasiak, A.: Commentary about the paper : The function of the secondary site of RecA protein during DNA strand exchange. CHEMTRACTS-Biochemistry and Molecular Biology 1998, 11:777-784.

    Serre, V., Dolci, W., Schaerer, E., Scrocchi, L., Drucker, D., Efrat, S., Thorens, B.: Exendin-(9-39) is an inverse agonist of the murine glucagon-like peptide-1 receptor: implications for basal intracellular cyclic adenosine 3',5'-monophosphate levels and beta-cell glucose competence. Endocrinology 1998, 139:4448-54. URL

    Reid, M. S., Nishino, S., Tafti, M., Siegel, J. M., Dement, W. C., Mignot, E.: Neuropharmacological characterization of basal forebrain cholinergic stimulated cataplexy in narcoleptic canines. Exp Neurol 1998, 151:89-104. URL

    Pralong, F. P., Roduit, R., Waeber, G., Castillo, E., Mosimann, F., Thorens, B., Gaillard, R. C.: Leptin inhibits directly glucocorticoid secretion by normal human and rat adrenal gland. Endocrinology 1998, 139:4264-8. URL

    Pessler, F., Hernandez, N.: The HIV-1 inducer of short transcripts activates the synthesis of 5,6-dichloro-1-beta-D-benzimidazole-resistant short transcripts in vitro. J Biol Chem 1998, 273:5375-84. URL

    Nigro, C. L., Venesio, T., Reymond, A., Meroni, G., Alberici, P., Cainarca, S., Enrico, F., Stack, M., Ledbetter, D. H., Liscia, D. S., Ballabio, A., Carrozzo, R.: The human ROX gene: genomic structure and mutation analysis in human breast tumors. Genomics 1998, 49:275-82. URL

    Marilley, D., Robyr, D., Schild-Poulter, C., Wahli, W.: Regulation of the vitellogenin gene B1 promoter after transfer into hepatocytes in primary cultures. Mol Cell Endocrinol 1998, 141:79-93. URL

    Laurie, B., Katritch, V., Sogo, J., Koller, T., Dubochet, J., Stasiak, A.: Geometry and physics of catenanes applied to the study of DNA replication. Biophys J 1998, 74:2815-22. URL

    Jeannin, E., Robyr, D., Desvergne, B.: Transcriptional regulatory patterns of the myelin basic protein and malic enzyme genes by the thyroid hormone receptors alpha1 and beta1. J Biol Chem 1998, 273:24239-48. URL

    Jarvis, P., Chen, L. J., Li, H., Peto, C. A., Fankhauser, C., Chory, J.: An Arabidopsis mutant defective in the plastid general protein import apparatus. Science 1998, 282:100-3. URL

    Hinkley, C. S., Blasco, M. A., Funk, W. D., Feng, J., Villeponteau, B., Greider, C. W., Herr, W.: The mouse telomerase RNA 5"-end lies just upstream of the telomerase template sequence. Nucleic Acids Res 1998, 26:532-6. URL

    Herr, W.: The herpes simplex virus VP16-induced complex: mechanisms of combinatorial transcriptional regulation. Cold Spring Harb Symp Quant Biol 1998, 63:599-607. URL

    Henry, R. W., Mittal, V., Ma, B., Kobayashi, R., Hernandez, N.: SNAP19 mediates the assembly of a functional core promoter complex (SNAPc) shared by RNA polymerases II and III. Genes Dev 1998, 12:2664-72. URL

    Henry, R. W., Ford, E., Mital, R., Mittal, V., Hernandez, N.: Crossing the line between RNA polymerases: transcription of human snRNA genes by RNA polymerases II and III. Cold Spring Harb Symp Quant Biol 1998, 63:111-20. URL

    Guillam, M. T., Burcelin, R., Thorens, B.: Normal hepatic glucose production in the absence of GLUT2 reveals an alternative pathway for glucose release from hepatocytes. Proc Natl Acad Sci U S A 1998, 95:12317-21. URL

    Fusco, C., Reymond, A., Zervos, A. S.: Molecular cloning and characterization of a novel retinoblastoma-binding protein. Genomics 1998, 51:351-8. URL

    Franken, P., Malafosse, A., Tafti, M.: Genetic variation in EEG activity during sleep in inbred mice. Am J Physiol 1998, 275:R1127-37. URL

    Ford, E., Strubin, M., Hernandez, N.: The Oct-1 POU domain activates snRNA gene transcription by contacting a region in the SNAPc largest subunit that bears sequence similarities to the Oct-1 coactivator OBF-1. Genes Dev 1998, 12:3528-40. URL

    Devchand, P., Wahli, W.: Leukotriene B4 : agonist for the fat regulator PPARα In Leukotrienes : New Concepts and Targets for Therapy Edited by Rodger, I. , Botting, J. , Dahlén, S.-E. ; London: William Harvey Press; 1998: 119-124.

    Desvergne, B., IJpenberg, A., Devchand, P. R., Wahli, W.: The peroxisome proliferator-activated receptors at the cross-road of diet and hormonal signalling. J Steroid Biochem Mol Biol 1998, 65:65-74. URL

    Cattley, R. C., DeLuca, J., Elcombe, C., Fenner-Crisp, P., Lake, B. G., Marsman, D. S., Pastoor, T. A., Popp, J. A., Robinson, D. E., Schwetz, B., Tugwood, J., Wahli, W.: Do peroxisome proliferating compounds pose a hepatocarcinogenic hazard to humans?. Regul Toxicol Pharmacol 1998, 27:47-60. URL

    Braissant, O., Wahli, W.: Differential expression of peroxisome proliferator-activated receptor-alpha, -beta, and -gamma during rat embryonic development. Endocrinology 1998, 139:2748-54. URL

    Braissant, O., Wahli, W.: A simplified in situ hybridization protocol using non-radioactively labelled probes to detect abundant and rare mRNAs on tissue sections. Biochemica 1998, 1:10-16.

    Besset, A., Villemin, E., Tafti, M., Billiard, M.: Homeostatic process and sleep spindles in patients with sleep-maintenance insomnia: effect of partial (21 h) sleep deprivation. Electroencephalogr Clin Neurophysiol 1998, 107:122-32. URL

    Almind, K., Ambye, L., Urhammer, S. A., Hansen, T., Echwald, S. M., Holst, J. J., Gromada, J., Thorens, B., Pedersen, O.: Discovery of amino acid variants in the human glucose-dependent insulinotropic polypeptide (GIP) receptor: the impact on the pancreatic beta cell responses and functional expression studies in Chinese hamster fibroblast cells. Diabetologia 1998, 41:1194-8. URL


1997

 

 
    Wilson, A. C., Freiman, R. N., Goto, H., Nishimoto, T., Herr, W.: VP16 targets an amino-terminal domain of HCF involved in cell cycle progression. Mol Cell Biol 1997, 17:6139-46. URL

    Willson, T. M., Wahli, W.: Peroxisome proliferator-activated receptor agonists. Curr Opin Chem Biol 1997, 1:235-41. URL

    Widmann, C., Dolci, W., Thorens, B.: Internalization and homologous desensitization of the GLP-1 receptor depend on phosphorylation of the receptor carboxyl tail at the same three sites. Mol Endocrinol 1997, 11:1094-102. URL

    Weber-Chappuis, K., Thorens, B.: [Histiocytosis X falsely diagnosed as silicosis]. Rev Med Suisse Romande 1997, 117:901-5. URL

    Waeber, G., Calandra, T., Roduit, R., Haefliger, J. A., Bonny, C., Thompson, N., Thorens, B., Temler, E., Meinhardt, A., Bacher, M., Metz, C. N., Nicod, P., Bucala, R.: Insulin secretion is regulated by the glucose-dependent production of islet beta cell macrophage migration inhibitory factor. Proc Natl Acad Sci U S A 1997, 94:4782-7. URL

    Tansey, W. P., Herr, W.: TAFs: guilt by association?. Cell 1997, 88:729-32. URL

    Tansey, W. P., Herr, W.: Selective use of TBP and TFIIB revealed by a TATA-TBP-TFIIB array with altered specificity. Science 1997, 275:829-31. URL

    Tafti, M., Nishino, S., Liao, W., Dement, W. C., Mignot, E.: Mesopontine organization of cholinergic and catecholaminergic cell groups in the normal and narcoleptic dog. J Comp Neurol 1997, 379:185-97. URL

    Tafti, M., Franken, P., Kitahama, K., Malafosse, A., Jouvet, M., Valatx, J. L.: Localization of candidate genomic regions influencing paradoxical sleep in mice. Neuroreport 1997, 8:3755-8. URL

    Stasiak, A., West, S. C., Egelman, E. H.: Sickle cell anemia research and a recombinant DNA technique. Science 1997, 277:460-2. URL

    Stasiak, A.: Noeuds idéaux et noeuds réels. Pour la Science 1997, La Science des Noeuds:106-111.

    Sepehri, S., Hernandez, N.: The largest subunit of human RNA polymerase III is closely related to the largest subunit of yeast and trypanosome RNA polymerase III. Genome Res 1997, 7:1006-19. URL

    Roduit, R., Thorens, B.: Inhibition of glucose-induced insulin secretion by long-term preexposure of pancreatic islets to leptin. FEBS Lett 1997, 415:179-82. URL

    Poirier, H., Braissant, O., Niot, I., Wahli, W., Besnard, P.: 9-cis-retinoic acid enhances fatty acid-induced expression of the liver fatty acid-binding protein gene. FEBS Lett 1997, 412:480-4. URL

    Pessler, F., Pendergrast, P. S., Hernandez, N.: Purification and characterization of FBI-1, a cellular factor that binds to the human immunodeficiency virus type 1 inducer of short transcripts. Mol Cell Biol 1997, 17:3786-98. URL

    Pendergrast, P. S., Hernandez, N.: RNA-targeted activators, but not DNA-targeted activators, repress the synthesis of short transcripts at the human immunodeficiency virus type 1 long terminal repeat. J Virol 1997, 71:910-7. URL

    Nunez, S. B., Medin, J. A., Braissant, O., Kemp, L., Wahli, W., Ozato, K., Segars, J. H.: Retinoid X receptor and peroxisome proliferator-activated receptor activate an estrogen responsive gene independent of the estrogen receptor. Mol Cell Endocrinol 1997, 127:27-40. URL

    Nishino, S., Tafti, M., Sampathkumaran, R., Dement, W. C., Mignot, E.: Circadian distribution of rest/activity in narcoleptic and control dogs: assessment with ambulatory activity monitoring. J Sleep Res 1997, 6:120-7. URL

    Mittal, V., Hernandez, N.: Role for the amino-terminal region of human TBP in U6 snRNA transcription. Science 1997, 275:1136-40. URL

    Mezard, C., Davies, A. A., Stasiak, A., West, S. C.: Biochemical properties of RuvBD113N: a mutation in helicase motif II of the RuvB hexamer affects DNA binding and ATPase activities. J Mol Biol 1997, 271:704-17. URL

    Meroni, G., Reymond, A., Alcalay, M., Borsani, G., Tanigami, A., Tonlorenzi, R., Nigro, C. L., Messali, S., Zollo, M., Ledbetter, D. H., Brent, R., Ballabio, A., Carrozzo, R.: Rox, a novel bHLHZip protein expressed in quiescent cells that heterodimerizes with Max, binds a non-canonical E box and acts as a transcriptional repressor. Embo J 1997, 16:2892-906. URL

    Masmoudi, T., Hihi, A. K., Vazquez, M., Artur, Y., Desvergne, B., Wahli, W., Goudonnet, H.: Transcriptional regulation by triiodothyronine of the UDP-glucuronosyltransferase family 1 gene complex in rat liver. Comparison with induction by 3-methylcholanthrene. J Biol Chem 1997, 272:17171-5. URL

    Lai, J. S., Herr, W.: Interdigitated residues within a small region of VP16 interact with Oct-1, HCF, and DNA. Mol Cell Biol 1997, 17:3937-46. URL

    Krey, G., Braissant, O., L'Horset, F., Kalkhoven, E., Perroud, M., Parker, M. G., Wahli, W.: Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay. Mol Endocrinol 1997, 11:779-91. URL

    Kliewer, S. A., Sundseth, S. S., Jones, S. A., Brown, P. J., Wisely, G. B., Koble, C. S., Devchand, P., Wahli, W., Willson, T. M., Lenhard, J. M., Lehmann, J. M.: Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma. Proc Natl Acad Sci U S A 1997, 94:4318-23. URL

    Kiianitsa, K., Stasiak, A.: Helical repeat of DNA in the region of homologous pairing. Proc Natl Acad Sci U S A 1997, 94:7837-40. URL

    Keller, H., Wahli, W.: Steroid hormone and related receptors In Principles of Medical Biology, Molecular and Cellular Endocrinology Volume 10A. Edited by Bittar, E.E. , Bittar, N. ; Greenwich, USA: JAI Press Inc.; 1997: 255-296.

    Keller, H., Devchand, P. R., Perroud, M., Wahli, W.: PPAR alpha structure-function relationships derived from species-specific differences in responsiveness to hypolipidemic agents. Biol Chem 1997, 378:651-5. URL

    Katritch, V., Olson, W. K., Pieranski, P., Dubochet, J., Stasiak, A.: Properties of ideal composite knots. Nature 1997, 388:148-51. URL

    Juge-Aubry, C., Pernin, A., Favez, T., Burger, A. G., Wahli, W., Meier, C. A., Desvergne, B.: DNA binding properties of peroxisome proliferator-activated receptor subtypes on various natural peroxisome proliferator response elements. Importance of the 5'-flanking region. J Biol Chem 1997, 272:25252-9. URL

    Ijpenberg, A., Jeannin, E., Wahli, W., Desvergne, B.: Polarity and specific sequence requirements of peroxisome proliferator-activated receptor (PPAR)/retinoid X receptor heterodimer binding to DNA. A functional analysis of the malic enzyme gene PPAR response element. J Biol Chem 1997, 272:20108-17. URL

    Guillam, M. T., Hummler, E., Schaerer, E., Yeh, J. I., Birnbaum, M. J., Beermann, F., Schmidt, A., Deriaz, N., Thorens, B.: Early diabetes and abnormal postnatal pancreatic islet development in mice lacking Glut-2. Nat Genet 1997, 17:327-30. URL

    Gremlich, S., Roduit, R., Thorens, B.: Dexamethasone induces posttranslational degradation of GLUT2 and inhibition of insulin secretion in isolated pancreatic beta cells. Comparison with the effects of fatty acids. J Biol Chem 1997, 272:3216-22. URL

    Gremlich, S., Bonny, C., Waeber, G., Thorens, B.: Fatty acids decrease IDX-1 expression in rat pancreatic islets and reduce GLUT2, glucokinase, insulin, and somatostatin levels. J Biol Chem 1997, 272:30261-9. URL

    Goto, H., Motomura, S., Wilson, A. C., Freiman, R. N., Nakabeppu, Y., Fukushima, K., Fujishima, M., Herr, W., Nishimoto, T.: A single-point mutation in HCF causes temperature-sensitive cell-cycle arrest and disrupts VP16 function. Genes Dev 1997, 11:726-37. URL

    Furrer, P., Bednar, J., Stasiak, A. Z., Katritch, V., Michoud, D., Stasiak, A., Dubochet, J.: Opposite effect of counterions on the persistence length of nicked and non-nicked DNA. J Mol Biol 1997, 266:711-21. URL

    Freiman, R. N., Herr, W.: Viral mimicry: common mode of association with HCF by VP16 and the cellular protein LZIP. Genes Dev 1997, 11:3122-7. URL

    Ford, E., Hernandez, N.: Characterization of a trimeric complex containing Oct-1, SNAPc, and DNA. J Biol Chem 1997, 272:16048-55. URL

    Fankhauser, C., Chory, J.: Light control of plant development. Annu Rev Cell Dev Biol 1997, 13:203-29. URL

    Devchand, P., Wahli, W.: Tempting fate with fat In Hormones and Signalling Volume 1. Edited by Academic Press; 1997: 235-256.

    Desvergne, B., Favez, T.: The major transcription initiation site of the SV40 late promoter is a potent thyroid hormone response element. Nucleic Acids Res 1997, 25:1774-81. URL

    Cleary, M. A., Pendergrast, P. S., Herr, W.: Structural flexibility in transcription complex formation revealed by protein-DNA photocrosslinking. Proc Natl Acad Sci U S A 1997, 94:8450-5. URL

    Bonny, C., Roduit, R., Gremlich, S., Nicod, P., Thorens, B., Waeber, G.: The loss of GLUT2 expression in the pancreatic beta-cells of diabetic db/db mice is associated with an impaired DNA-binding activity of islet-specific trans-acting factors. Mol Cell Endocrinol 1997, 135:59-65. URL

    Batistuzzo de Medeiros, S. R., Krey, G., Hihi, A. K., Wahli, W.: Functional interactions between the estrogen receptor and the transcription activator Sp1 regulate the estrogen-dependent transcriptional activity of the vitellogenin A1 io promoter. J Biol Chem 1997, 272:18250-60. URL

    Babb, R., Cleary, M. A., Herr, W.: OCA-B is a functional analog of VP16 but targets a separate surface of the Oct-1 POU domain. Mol Cell Biol 1997, 17:7295-305. URL

    Atanasoski, S., Schreiber, E., Fontana, A., Herr, W.: N-Oct 5 is generated by in vitro proteolysis of the neural POU-domain protein N-Oct 3. Oncogene 1997, 14:1287-94. URL


1996

 

 
    Widmann, C., Dolci, W., Thorens, B.: Desensitization and phosphorylation of the glucagon-like peptide-1 (GLP-1) receptor by GLP-1 and 4-phorbol 12-myristate 13-acetate. Mol Endocrinol 1996, 10:62-75. URL

    Widmann, C., Dolci, W., Thorens, B.: Heterologous desensitization of the glucagon-like peptide-1 receptor by phorbol esters requires phosphorylation of the cytoplasmic tail at four different sites. J Biol Chem 1996, 271:19957-63. URL

    Thorens, B., Widmann, C.: Signal transduction and desensitization of the glucagon-like peptide-1 receptor. Acta Physiol Scand 1996, 157:317-9. URL

    Thorens, B., Roth, J.: Intracellular targeting of GLUT4 in transfected insulinoma cells: evidence for association with constitutively recycling vesicles distinct from synaptophysin and insulin vesicles. J Cell Sci 1996, 109 ( Pt 6):1311-23. URL

    Thorens, B., Gremlich, S., Roduit, R., Widmann, C.: [1996 Apollinaire Bouchardat Prize. Molecular aspects of control of insulin secretion]. Journ Annu Diabetol Hotel Dieu 1996,
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    Thorens, B., Deriaz, N., Bosco, D., DeVos, A., Pipeleers, D., Schuit, F., Meda, P., Porret, A.: Protein kinase A-dependent phosphorylation of GLUT2 in pancreatic beta cells. J Biol Chem 1996, 271:8075-81. URL

    Thorens, B.: Glucose transporters in the regulation of intestinal, renal, and liver glucose fluxes. Am J Physiol 1996, 270:G541-53. URL

    Tafti, M., Nishino, S., Aldrich, M. S., Liao, W., Dement, W. C., Mignot, E.: Major histocompatibility class II molecules in the CNS: increased microglial expression at the onset of narcolepsy in canine model. J Neurosci 1996, 16:4588-95. URL

    Stasiak, A., Katritch, V., Bednar, J., Michoud, D., Dubochet, J.: Electrophoretic mobility of DNA knots. Nature 1996, 384:122. URL

    Stasiak, A, Bednar, J., Furrer, P., Katritch, V., Stasiak, A.Z., Dubochet, J.: Elasticity of DNA as directly measured by cryo-electron microscopy In Biological structure and dynamics Volume II. Edited by R.H. Sarma, M.H. Sarma; Adenine Press; 1996: 259-266.

    Stasiak, A., Bednar, J., Furrer, P., Katritch, V., Dubochet, J.: Determination of the DNA helical repeat and of the structure of supercoiled DNA by cryo-electron microscopy In IMA volumes in mathematics ands its applications Volume 82, Mathematical approaches to biomolecular structure and dynamics. Edited by J.P. Mesirov, K. Schulten, D.W. Sumners; New-York: Springer-Verlag; 1996: 117-138.

    Stasiak, A.: Circular DNA In Large ring molecules Edited by J.A. Semlyen; John Wiley & Sons Ltd.; 1996: 43-97.

    Stasiak, A.: Getting down to the core of homologous recombination. Science 1996, 272:828-9. URL

    Sohrmann, M., Fankhauser, C., Brodbeck, C., Simanis, V.: The dmf1/mid1 gene is essential for correct positioning of the division septum in fission yeast. Genes Dev 1996, 10:2707-19. URL

    Shalev, A., Siegrist-Kaiser, C. A., Yen, P. M., Wahli, W., Burger, A. G., Chin, W. W., Meier, C. A.: The peroxisome proliferator-activated receptor alpha is a phosphoprotein: regulation by insulin. Endocrinology 1996, 137:4499-502. URL

    Sadowski, C. L., Henry, R. W., Kobayashi, R., Hernandez, N.: The SNAP45 subunit of the small nuclear RNA (snRNA) activating protein complex is required for RNA polymerase II and III snRNA gene transcription and interacts with the TATA box binding protein. Proc Natl Acad Sci U S A 1996, 93:4289-93. URL

    Ruppert, S. M., McCulloch, V., Meyer, M., Bautista, C., Falkowski, M., Stunnenberg, H. G., Hernandez, N.: Monoclonal antibodies directed against the amino-terminal domain of human TBP cross-react with TBP from other species. Hybridoma 1996, 15:55-68. URL

    Reid, M. S., Tafti, M., Nishino, S., Sampathkumaran, R., Siegel, J. M., Mignot, E.: Local administration of dopaminergic drugs into the ventral tegmental area modulates cataplexy in the narcoleptic canine. Brain Res 1996, 733:83-100. URL

    Pendergrast, P. S., Morrison, D., Tansey, W. P., Hernandez, N.: Mutations in the carboxy-terminal domain of TBP affect the synthesis of human immunodeficiency virus type 1 full-length and short transcripts similarly. J Virol 1996, 70:5025-34. URL

    Moens, K., Heimberg, H., Flamez, D., Huypens, P., Quartier, E., Ling, Z., Pipeleers, D., Gremlich, S., Thorens, B., Schuit, F.: Expression and functional activity of glucagon, glucagon-like peptide I, and glucose-dependent insulinotropic peptide receptors in rat pancreatic islet cells. Diabetes 1996, 45:257-61. URL

    Mittal, V., Cleary, M. A., Herr, W., Hernandez, N.: The Oct-1 POU-specific domain can stimulate small nuclear RNA gene transcription by stabilizing the basal transcription complex SNAPc. Mol Cell Biol 1996, 16:1955-65. URL

    Mital, R., Kobayashi, R., Hernandez, N.: RNA polymerase III transcription from the human U6 and adenovirus type 2 VAI promoters has different requirements for human BRF, a subunit of human TFIIIB. Mol Cell Biol 1996, 16:7031-42. URL

    Lemberger, T., Saladin, R., Vazquez, M., Assimacopoulos, F., Staels, B., Desvergne, B., Wahli, W., Auwerx, J.: Expression of the peroxisome proliferator-activated receptor alpha gene is stimulated by stress and follows a diurnal rhythm. J Biol Chem 1996, 271:1764-9. URL

    Lemberger, T., Desvergne, B., Wahli, W.: Peroxisome proliferator-activated receptors: a nuclear receptor signaling pathway in lipid physiology. Annu Rev Cell Dev Biol 1996, 12:335-63. URL

    Lemberger, T., Braissant, O., Juge-Aubry, C., Keller, H., Saladin, R., Staels, B., Auwerx, J., Burger, A. G., Meier, C. A., Wahli, W.: PPAR tissue distribution and interactions with other hormone-signaling pathways. Ann N Y Acad Sci 1996, 804:231-51. URL

    LaMarco, K., Wilson, A.C., and Herr, W.: Herpes simplex virus drug screen. 1996,


    Katritch, V., Bednar, J., Michoud, D., Scharein, R.G., Dubochet, J., Stasiak, A.: Geometry and physics of knots. Nature 1996, 384:142-196.

    Kanbayashi, T., Nishino, S., Tafti, M., Hishikawa, Y., Dement, W. C., Mignot, E.: Thalidomide, immune modulation and narcolepsy. Sleep 1996, 19:116. URL

    Kanbayashi, T., Nishino, S., Tafti, M., Hishikawa, Y., Dement, W. C., Mignot, E.: Thalidomide, a hypnotic with immune modulating properties, increases cataplexy in canine narcolepsy. Neuroreport 1996, 7:1881-6. URL

    Huang, C. C., Herr, W.: Differential control of transcription by homologous homeodomain coregulators. Mol Cell Biol 1996, 16:2967-76. URL

    Henry, R. W., Ma, B., Sadowski, C. L., Kobayashi, R., Hernandez, N.: Cloning and characterization of SNAP50, a subunit of the snRNA-activating protein complex SNAPc. Embo J 1996, 15:7129-36. URL

    Devchand, P. R., Keller, H., Peters, J. M., Vazquez, M., Gonzalez, F. J., Wahli, W.: The PPARalpha-leukotriene B4 pathway to inflammation control. Nature 1996, 384:39-43. URL

    Desvergne, B.: Book review of Peroxisome proliferation and its role in carcinogenesis. ISSX Newsletter 1996, 16:

    Chory, J., Chatterjee, M., Cook, R. K., Elich, T., Fankhauser, C., Li, J., Nagpal, P., Neff, M., Pepper, A., Poole, D., Reed, J., Vitart, V.: From seed germination to flowering, light controls plant development via the pigment phytochrome. Proc Natl Acad Sci U S A 1996, 93:12066-71. URL

    Braissant, O., Foufelle, F., Scotto, C., Dauca, M., Wahli, W.: Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat. Endocrinology 1996, 137:354-66. URL

    Alvarez, E., Roncero, I., Chowen, J. A., Thorens, B., Blazquez, E.: Expression of the glucagon-like peptide-1 receptor gene in rat brain. J Neurochem 1996, 66:920-7. URL


1995

 

 
    Wilson, A. C., Peterson, M. G., Herr, W.: The HCF repeat is an unusual proteolytic cleavage signal. Genes Dev 1995, 9:2445-58. URL

    Wilson, A. C., Parrish, J. E., Massa, H. F., Nelson, D. L., Trask, B. J., Herr, W.: The gene encoding the VP16-accessory protein HCF (HCFC1) resides in human Xq28 and is highly expressed in fetal tissues and the adult kidney. Genomics 1995, 25:462-8. URL

    Widmann, C., Dolci, W., Thorens, B.: Agonist-induced internalization and recycling of the glucagon-like peptide-1 receptor in transfected fibroblasts and in insulinomas. Biochem J 1995, 310 ( Pt 1):203-14. URL

    Wahli, W., Braissant, O., Desvergne, B.: Peroxisome proliferator activated receptors: transcriptional regulators of adipogenesis, lipid metabolism and more. Chem Biol 1995, 2:261-6. URL

    Thorens, B.: Glucagon-like peptide-1 and control of insulin secretion. Diabete Metab 1995, 21:311-8. URL

    ten Heggeler-Bordier, B., Schild-Poulter, C., Chapel, S., Wahli, W.: Fate of linear and supercoiled multinucleosomic templates during transcription. Embo J 1995, 14:2561-9. URL

    Tansey, W. P., Herr, W.: The ability to associate with activation domains in vitro is not required for the TATA box-binding protein to support activated transcription in vivo. Proc Natl Acad Sci U S A 1995, 92:10550-4. URL

    Schoonjans, K., Watanabe, M., Suzuki, H., Mahfoudi, A., Krey, G., Wahli, W., Grimaldi, P., Staels, B., Yamamoto, T., Auwerx, J.: Induction of the acyl-coenzyme A synthetase gene by fibrates and fatty acids is mediated by a peroxisome proliferator response element in the C promoter. J Biol Chem 1995, 270:19269-76. URL

    Roulet, E., Armentero, M. T., Krey, G., Corthesy, B., Dreyer, C., Mermod, N., Wahli, W.: Regulation of the DNA-binding and transcriptional activities of Xenopus laevis NFI-X by a novel C-terminal domain. Mol Cell Biol 1995, 15:5552-62. URL

    Reymond, A., Brent, R.: p16 proteins from melanoma-prone families are deficient in binding to Cdk4. Oncogene 1995, 11:1173-8. URL

    Regazzi, R., Wollheim, C. B., Lang, J., Theler, J. M., Rossetto, O., Montecucco, C., Sadoul, K., Weller, U., Palmer, M., Thorens, B.: VAMP-2 and cellubrevin are expressed in pancreatic beta-cells and are essential for Ca(2+)-but not for GTP gamma S-induced insulin secretion. Embo J 1995, 14:2723-30. URL

    Parsons, C. A., Stasiak, A., West, S. C.: The E.coli RuvAB proteins branch migrate Holliday junctions through heterologous DNA sequences in a reaction facilitated by SSB. Embo J 1995, 14:5736-44. URL

    Parsons, C. A., Stasiak, A., Bennett, R. J., West, S. C.: Structure of a multisubunit complex that promotes DNA branch migration. Nature 1995, 374:375-8. URL

    Ogawa, Y., Noma, Y., Davalli, A. M., Wu, Y. J., Thorens, B., Bonner-Weir, S., Weir, G. C.: Loss of glucose-induced insulin secretion and GLUT2 expression in transplanted beta-cells. Diabetes 1995, 44:75-9. URL

    Nunez, S. B., Medin, J. A., Keller, H., Wang, K., Ozato, K., Wahli, W., Segars, J.: Retinoid X receptor beta and peroxisome proliferator-activated receptor activate an estrogen response element. Recent Prog Horm Res 1995, 50:409-16. URL

    Nishino, S., Tafti, M., Reid, M. S., Shelton, J., Siegel, J. M., Dement, W. C., Mignot, E.: Muscle atonia is triggered by cholinergic stimulation of the basal forebrain: implication for the pathophysiology of canine narcolepsy. J Neurosci 1995, 15:4806-14. URL

    Neuville, P., Vanier, M. T., Michalik, L., Launay, J. F.: In situ localization with digoxigenin-labelled probes of tau-related mRNAs in the rat pancreas. Histochem J 1995, 27:565-74. URL

    Mignot, E., Tafti, M., Dement, W. C., Grumet, F. C.: Narcolepsy and immunity. Adv Neuroimmunol 1995, 5:23-37. URL

    Michalik, L., Neuville, P., Vanier, M. T., Launay, J. F.: Pancreatic tau related maps: biochemical and immunofluorescence analysis in a tumoral cell line. Mol Cell Biochem 1995, 143:107-12. URL

    Mahfoudi, A., Roulet, E., Dauvois, S., Parker, M. G., Wahli, W.: Specific mutations in the estrogen receptor change the properties of antiestrogens to full agonists. Proc Natl Acad Sci U S A 1995, 92:4206-10. URL

    Lyubchenko, Y. L., Jacobs, B. L., Lindsay, S. M., Stasiak, A.: Atomic force microscopy of nucleoprotein complexes. Scanning Microsc 1995, 9:705-24; discussion 724-7. URL

    LaMarco, K., Wilson, A.C., and Herr, W.: Eukaryotic transcription protein; host cell factor. 1995,


    Krey, G., Mahfoudi, A., Wahli, W.: Functional interactions of peroxisome proliferator-activated receptor, retinoid-X receptor, and Sp1 in the transcriptional regulation of the acyl-coenzyme-A oxidase promoter. Mol Endocrinol 1995, 9:219-31. URL

    Krey, G., Keller, H., Mahfoudi, A., Wahli, W.: PPARs : Nuclear hormone receptors controlling peroxisomal fatty acid β-oxidation In Functions and Biogenesis of Peroxisomes in Relation to Human Disease Edited by R.J.A. Wanders, R.B.H. Schutgens , H.F. Tabak; North-Holland, Amsterdam, Oxford, New York, Tokyo: 1995: 167-200.

    Keller, H., Givel, F., Perroud, M., Wahli, W.: Signaling cross-talk between peroxisome proliferator-activated receptor/retinoid X receptor and estrogen receptor through estrogen response elements. Mol Endocrinol 1995, 9:794-804. URL

    Katritch, V., Bednar, J., Furrer, P., Pinol-I-Margalef, F., Kunt, M., Vologodskii, A., Stasiak, A., Dubochet, J.: Persistence length of DNA molecules confined to the thin liquid layer. II. From stereomicrographs of DNA molecules to their reconstructed trajectories. Automatic procedure of filament recognition and its adaptation for the measurement of DNA persistence length.. Journal of Molecular Biology 1995, 254:591-594.

    Juge-Aubry, C. E., Gorla-Bajszczak, A., Pernin, A., Lemberger, T., Wahli, W., Burger, A. G., Meier, C. A.: Peroxisome proliferator-activated receptor mediates cross-talk with thyroid hormone receptor by competition for retinoid X receptor. Possible role of a leucine zipper-like heptad repeat. J Biol Chem 1995, 270:18117-22. URL

    Jansen, J. H., Mahfoudi, A., Rambaud, S., Lavau, C., Wahli, W., Dejean, A.: Multimeric complexes of the PML-retinoic acid receptor alpha fusion protein in acute promyelocytic leukemia cells and interference with retinoid and peroxisome-proliferator signaling pathways. Proc Natl Acad Sci U S A 1995, 92:7401-5. URL

    Herr, W. and Kingston, R. : Chromosomes and expression mechanisms: Editorial overview.. Curr. Opin. Genet. Dev. 1995,


    Herr, W., Kingston, R. : Chromosomes and expression mechanisms: Editorial overview. Curr. Opin. Genet. Dev. 1995, 5:151-152. URL

    Herr, W., Cleary, M. A.: The POU domain: versatility in transcriptional regulation by a flexible two-in-one DNA-binding domain. Genes Dev 1995, 9:1679-93. URL

    Henry, R. W., Sadowski, C. L., Kobayashi, R., Hernandez, N.: A TBP-TAF complex required for transcription of human snRNA genes by RNA polymerase II and III. Nature 1995, 374:653-6. URL

    Heimberg, H., De Vos, A., Pipeleers, D., Thorens, B., Schuit, F.: Differences in glucose transporter gene expression between rat pancreatic alpha- and beta-cells are correlated to differences in glucose transport but not in glucose utilization. J Biol Chem 1995, 270:8971-5. URL

    Gros, L., Hollande, F., Thorens, B., Kervran, A., Bataille, D.: Comparative effects of GLP-1-(7-36) amide, oxyntomodulin and glucagon on rabbit gastric parietal cell function. Eur J Pharmacol 1995, 288:319-27. URL

    Gremlich, S., Porret, A., Hani, E. H., Cherif, D., Vionnet, N., Froguel, P., Thorens, B.: Cloning, functional expression, and chromosomal localization of the human pancreatic islet glucose-dependent insulinotropic polypeptide receptor. Diabetes 1995, 44:1202-8. URL

    Fankhauser, C., Reymond, A., Cerutti, L., Utzig, S., Hofmann, K., Simanis, V.: The S. pombe cdc15 gene is a key element in the reorganization of F-actin at mitosis. Cell 1995, 82:435-44. URL

    Desvergne, B., Wahli, W.: PPAR : A key factor in nutrient/gene interactions In Inducible Transcription Volume 1. Edited by Baeuerle, P. ; Boston, Basel, Berlin: Birkhäuser; 1995: 142-176.

    Desvergne, B., Wahli, W.: PPAR: a key nuclear factor in nutrient/gene interactions ? In Inducible transcription Volume 1. Edited by Baeuerle, P. ; Boston: Birkhäuser; 1995: 142-176.

    Das, G., Hinkley, C. S., Herr, W.: Basal promoter elements as a selective determinant of transcriptional activator function. Nature 1995, 374:657-60. URL

    Cleary, M. A., Herr, W.: Mechanisms for flexibility in DNA sequence recognition and VP16-induced complex formation by the Oct-1 POU domain. Mol Cell Biol 1995, 15:2090-100. URL

    Bosco, D., Meda, P., Thorens, B., Malaisse, W. J.: Heterogeneous secretion of individual B cells in response to D-glucose and to nonglucidic nutrient secretagogues. Am J Physiol 1995, 268:C611-8. URL

    Besset, A., Tafti, M., Villemin, E., Borderies, P., Billiard, M.: Effects of zolpidem on the architecture and cyclical structure of sleep in poor sleepers. Drugs Exp Clin Res 1995, 21:161-9. URL

    Bednar, J., Furrer, P., Katritch, V., Stasiak, A. Z., Dubochet, J., Stasiak, A.: Determination of DNA persistence length by cryo-electron microscopy. Separation of the static and dynamic contributions to the apparent persistence length of DNA. J Mol Biol 1995, 254:579-94. URL

    Alevizopoulos, A., Dusserre, Y., Tsai-Pflugfelder, M., von der Weid, T., Wahli, W., Mermod, N.: A proline-rich TGF-beta-responsive transcriptional activator interacts with histone H3. Genes Dev 1995, 9:3051-66. URL


1994

 

 
    Widmann, C., Burki, E., Dolci, W., Thorens, B.: Signal transduction by the cloned glucagon-like peptide-1 receptor: comparison with signaling by the endogenous receptors of beta cell lines. Mol Pharmacol 1994, 45:1029-35. URL

    Thorens, B., Roduit, R.: Regulated expression of GLUT2 in diabetes studied in transplanted pancreatic beta cells. Biochem Soc Trans 1994, 22:684-7. URL

    Thorens, B.: [GLP-1 and the control of insulin secretion]. Journ Annu Diabetol Hotel Dieu 1994,
    33-46. URL

    Tansey, W. P., Ruppert, S., Tjian, R., Herr, W.: Multiple regions of TBP participate in the response to transcriptional activators in vivo. Genes Dev 1994, 8:2756-69. URL

    Tanaka, M., Herr, W.: Reconstitution of transcriptional activation domains by reiteration of short peptide segments reveals the modular organization of a glutamine-rich activation domain. Mol Cell Biol 1994, 14:6056-67. URL

    Tanaka, M., Clouston, W. M., Herr, W.: The Oct-2 glutamine-rich and proline-rich activation domains can synergize with each other or duplicates of themselves to activate transcription. Mol Cell Biol 1994, 14:6046-55. URL

    Stasiak, A., Tsaneva, I. R., West, S. C., Benson, C. J., Yu, X., Egelman, E. H.: The Escherichia coli RuvB branch migration protein forms double hexameric rings around DNA. Proc Natl Acad Sci U S A 1994, 91:7618-22. URL

    Stasiak, A., Egelman, E. H.: Structure and function of RecA-DNA complexes. Experientia 1994, 50:192-203. URL

    Reid, M. S., Tafti, M., Nishino, S., Siegel, J. M., Dement, W. C., Mignot, E.: Cholinergic regulation of cataplexy in canine narcolepsy in the pontine reticular formation is mediated by M2 muscarinic receptors. Sleep 1994, 17:424-35. URL

    Reid, M. S., Tafti, M., Geary, J. N., Nishino, S., Siegel, J. M., Dement, W. C., Mignot, E.: Cholinergic mechanisms in canine narcolepsy--I. Modulation of cataplexy via local drug administration into the pontine reticular formation. Neuroscience 1994, 59:511-22. URL

    Orellana, C., Villemin, E., Tafti, M., Carlander, B., Besset, A., Billiard, M.: Life events in the year preceding the onset of narcolepsy. Sleep 1994, 17:S50-3. URL

    Morel, P., Stasiak, A., Ehrlich, S. D., Cassuto, E.: Effect of length and location of heterologous sequences on RecA-mediated strand exchange. J Biol Chem 1994, 269:19830-5. URL

    Marilley, D., Mahfoudi, A., Wahli, W.: Gene transfer into Xenopus hepatocytes: transcriptional regulation by members of the nuclear receptor superfamily. Mol Cell Endocrinol 1994, 101:227-36. URL

    Lobo, S., Hernandez, N. : Transcription of snRNA genes by RNA polymerases II and III. In Transcription, Mechanisms and Regulation, Raven Press Series on Molecular and Cellular Biology Edited by Conaway, R.C., Conaway, J.W.,; Raven Press ; 1994: 127-159.

    Lemberger, T., Staels, B., Saladin, R., Desvergne, B., Auwerx, J., Wahli, W.: Regulation of the peroxisome proliferator-activated receptor alpha gene by glucocorticoids. J Biol Chem 1994, 269:24527-30. URL

    Lazar, J., Desvergne, B., Zimmerman, E. C., Zimmer, D. B., Magnuson, M. A., Nikodem, V. M.: A role for intronic sequences on expression of thyroid hormone receptor alpha gene. J Biol Chem 1994, 269:20352-9. URL

    Klemm, J. D., Rould, M. A., Aurora, R., Herr, W., Pabo, C. O.: Crystal structure of the Oct-1 POU domain bound to an octamer site: DNA recognition with tethered DNA-binding modules. Cell 1994, 77:21-32. URL

    Hirsch, M., Carlander, B., Verge, M., Tafti, M., Anaya, J. M., Billiard, M., Sany, J.: Objective and subjective sleep disturbances in patients with rheumatoid arthritis. A reappraisal. Arthritis Rheum 1994, 37:41-9. URL

    Green, S., Wahli, W.: Peroxisome proliferator-activated receptors: finding the orphan a home. Mol Cell Endocrinol 1994, 100:149-53. URL

    Fankhauser, C., Simanis, V.: The cdc7 protein kinase is a dosage dependent regulator of septum formation in fission yeast. Embo J 1994, 13:3011-9. URL

    Fankhauser, C., Simanis, V.: Cold fission: splitting the pombe cell at room temperature. Trends Cell Biol 1994, 4:96-101. URL

    Ellinger-Ziegelbauer, H., Hihi, A. K., Laudet, V., Keller, H., Wahli, W., Dreyer, C.: FTZ-F1-related orphan receptors in Xenopus laevis: transcriptional regulators differentially expressed during early embryogenesis. Mol Cell Biol 1994, 14:2786-97. URL

    Dubochet, J., Bednar, J., Furrer, P., Stasiak, A. Z., Stasiak, A., Bolshoy, A. A.: Determination of the DNA helical repeat by cryo-electron microscopy. Nat Struct Biol 1994, 1:361-3. URL

    Dubochet, J., Bednar, J., Furrer, P., Stasiak, A.: Cryo-electron microscopy of DNA In Nucleic Acids and Molecular Biology Volume 8. Edited by Eckstein, F. , Lilley, D.M.J. ; Springer-Verlag; 1994: 41-55.

    Dubochet, J., Bednar, J., Furrer, P., Stasiak, A., Sarma, M.H. , Sarma, R.H. : Structure of supercoiled DNA changes with increasing counterions' concentrations; cryo-electron microscopy studies and Monte Carlo simulations. Structural Biology: the state of the art. Proceedings of the Eight Conversation in Biomolecular Stereodynamics 1994, 1:149-156.

    Desvergne, B.: How do thyroid hormone receptors bind to structurally diverse response elements?. Mol Cell Endocrinol 1994, 100:125-31. URL

    Claret, F. X., Chapel, S., Garces, J., Tsai-Pflugfelder, M., Bertholet, C., Shapiro, D. J., Wittek, R., Wahli, W.: Two functional forms of the Xenopus laevis estrogen receptor translated from a single mRNA species. J Biol Chem 1994, 269:14047-55. URL

    Cardinaux, J. R., Chapel, S., Wahli, W.: Complex organization of CTF/NF-I, C/EBP, and HNF3 binding sites within the promoter of the liver-specific vitellogenin gene. J Biol Chem 1994, 269:32947-56. URL

    Canessa, C. M., Schild, L., Buell, G., Thorens, B., Gautschi, I., Horisberger, J. D., Rossier, B. C.: Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits. Nature 1994, 367:463-7. URL

    Besset, A., Tafti, M., Nobile, L., Billiard, M.: Homeostasis and narcolepsy. Sleep 1994, 17:S29-34. URL

    Benson, F. E., Stasiak, A., West, S. C.: Purification and characterization of the human Rad51 protein, an analogue of E. coli RecA. Embo J 1994, 13:5764-71. URL

    Bednar, J., Furrer, P., Stasiak, A., Dubochet, J., Egelman, E. H., Bates, A. D.: The twist, writhe and overall shape of supercoiled DNA change during counterion-induced transition from a loosely to a tightly interwound superhelix. Possible implications for DNA structure in vivo. J Mol Biol 1994, 235:825-47. URL


1993

 

 
    Wilson, A. C., LaMarco, K., Peterson, M. G., Herr, W.: The VP16 accessory protein HCF is a family of polypeptides processed from a large precursor protein. Cell 1993, 74:115-25. URL

    Wilson, A. C., Cleary, M. A., Lai, J. S., LaMarco, K., Peterson, M. G., Herr, W.: Combinatorial control of transcription: the herpes simplex virus VP16-induced complex. Cold Spring Harb Symp Quant Biol 1993, 58:167-78. URL

    Wahli, W.: Fatty acids control gene expression through members of the nuclear receptor superfamily In Schering Lecturer's Publication Volume 18. Schering Lecturer's Publication; 1993: 1-24.

    Thorens, B., Waeber, G.: Glucagon-like peptide-I and the control of insulin secretion in the normal state and in NIDDM. Diabetes 1993, 42:1219-25. URL

    Thorens, B., Porret, A., Buhler, L., Deng, S. P., Morel, P., Widmann, C.: Cloning and functional expression of the human islet GLP-1 receptor. Demonstration that exendin-4 is an agonist and exendin-(9-39) an antagonist of the receptor. Diabetes 1993, 42:1678-82. URL

    Thorens, B., Gerard, N., Deriaz, N.: GLUT2 surface expression and intracellular transport via the constitutive pathway in pancreatic beta cells and insulinoma: evidence for a block in trans-Golgi network exit by brefeldin A. J Cell Biol 1993, 123:1687-94. URL

    Thorens, B.: Facilitated glucose transporters in epithelial cells. Annu Rev Physiol 1993, 55:591-608. URL

    Sonka, K., Tafti, M., Billiard, M.: [Polysomnography findings in middle-aged and elderly narcoleptics]. Sb Lek 1993, 94:333-44. URL

    Sheldon, M., Ratnasabapathy, R., Hernandez, N.: Characterization of the inducer of short transcripts, a human immunodeficiency virus type 1 transcriptional element that activates the synthesis of short RNAs. Mol Cell Biol 1993, 13:1251-63. URL

    Segars, J. H., Marks, M. S., Hirschfeld, S., Driggers, P. H., Martinez, E., Grippo, J. F., Brown, M., Wahli, W., Ozato, K.: Inhibition of estrogen-responsive gene activation by the retinoid X receptor beta: evidence for multiple inhibitory pathways. Mol Cell Biol 1993, 13:2258-68. URL

    Schild, C., Claret, F. X., Wahli, W., Wolffe, A. P.: A nucleosome-dependent static loop potentiates estrogen-regulated transcription from the Xenopus vitellogenin B1 promoter in vitro. Embo J 1993, 12:423-33. URL

    Sadowski, C. L., Henry, R. W., Lobo, S. M., Hernandez, N.: Targeting TBP to a non-TATA box cis-regulatory element: a TBP-containing complex activates transcription from snRNA promoters through the PSE. Genes Dev 1993, 7:1535-48. URL

    Reymond, A., Simanis, V.: Domains of p85cdc10 required for function of the fission yeast DSC-1 factor. Nucleic Acids Res 1993, 21:3615-21. URL

    Reymond, A., Marks, J., Simanis, V.: The activity of S.pombe DSC-1-like factor is cell cycle regulated and dependent on the activity of p34cdc2. Embo J 1993, 12:4325-34. URL

    Polo, O., Tafti, M., Fraga, J., Billiard, M.: Pharyngeal CT studies in patients with mild or severe upper airway obstruction during sleep. Sleep 1993, 16:S152-5. URL

    Neuville, P., Michalik, L., Launay, J. F.: Identification of a microtubule-binding domain sequence in pancreatic messenger RNAs. Biochim Biophys Acta 1993, 1181:317-20. URL

    Michalik, L., Neuville, P., Vanier, M. T., Launay, J. F.: Biochemical and immunochemical identification of a microtubule-binding protein from bovine pancreas. Cell Motil Cytoskeleton 1993, 25:381-90. URL

    Mayeux, V., Tafti, M., Baldy-Moulinier, M., Valmier, J.: Developmental regulation of carbonic anhydrase expression in mouse dorsal root ganglia. Brain Res Dev Brain Res 1993, 71:201-8. URL

    Krey, G., Keller, H., Mahfoudi, A., Medin, J., Ozato, K., Dreyer, C., Wahli, W.: Xenopus peroxisome proliferator activated receptors: genomic organization, response element recognition, heterodimer formation with retinoid X receptor and activation by fatty acids. J Steroid Biochem Mol Biol 1993, 47:65-73. URL

    Keller, H., Wahli, W.: Peroxisome Proliferator-Activated Receptors. A link between endocrinology and nutrition ?. Trends in Endocrinology and Metabolism 1993, 4:291-296.

    Keller, H., Mahfoudi, A., Dreyer, C., Hihi, A. K., Medin, J., Ozato, K., Wahli, W.: Peroxisome proliferator-activated receptors and lipid metabolism. Ann N Y Acad Sci 1993, 684:157-73. URL

    Keller, H., Dreyer, C., Medin, J., Mahfoudi, A., Ozato, K., Wahli, W.: Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers. Proc Natl Acad Sci U S A 1993, 90:2160-4. URL

    Herr, W. , Seminars in Virology : The SV40 enhancer: Transcriptional regulation through a hierarchy of combinatorial interactions.. 1993,


    Herr, W. : The SV40 enhancer: Transcriptional regulation through a hierarchy of combinatorial interactions. In Seminars in Virology 1993: 3-13.

    Hernandez, N.: TBP, a universal eukaryotic transcription factor?. Genes Dev 1993, 7:1291-308. URL

    Gros, L., Thorens, B., Bataille, D., Kervran, A.: Glucagon-like peptide-1-(7-36) amide, oxyntomodulin, and glucagon interact with a common receptor in a somatostatin-secreting cell line. Endocrinology 1993, 133:631-8. URL

    Grobholz, R., Hacker, H. J., Thorens, B., Bannasch, P.: Reduction in the expression of glucose transporter protein GLUT 2 in preneoplastic and neoplastic hepatic lesions and reexpression of GLUT 1 in late stages of hepatocarcinogenesis. Cancer Res 1993, 53:4204-11. URL

    Fankhauser, C., Simanis, V.: The Schizosaccharomyces pombe cdc14 gene is required for septum formation and can also inhibit nuclear division. Mol Biol Cell 1993, 4:531-9. URL

    Fankhauser, C., Marks, J., Reymond, A., Simanis, V.: The S. pombe cdc16 gene is required both for maintenance of p34cdc2 kinase activity and regulation of septum formation: a link between mitosis and cytokinesis?. Embo J 1993, 12:2697-704. URL

    Egelman, E.H., Stasiak, A.: Electron Microscopy of RecA-DNA complexes: Two different states, their functional significance and relation to the solved crystal structure. Micron 1993, 24:309-324 (invited review).

    Dreyer, C., Keller, H., Mahfoudi, A., Laudet, V., Krey, G., Wahli, W.: Positive regulation of the peroxisomal beta-oxidation pathway by fatty acids through activation of peroxisome proliferator-activated receptors (PPAR). Biol Cell 1993, 77:67-76. URL

    Das, G., Herr, W.: Enhanced activation of the human histone H2B promoter by an Oct-1 variant generated by alternative splicing. J Biol Chem 1993, 268:25026-32. URL

    Cleary, M. A., Stern, S., Tanaka, M., Herr, W.: Differential positive control by Oct-1 and Oct-2: activation of a transcriptionally silent motif through Oct-1 and VP16 corecruitment. Genes Dev 1993, 7:72-83. URL

    Besset, A., Tafti, M., Villemin, E., Billiard, M.: [The effects of modafinil (300mg) on sleep, sleepiness and arousal in narcoleptic patients]. Neurophysiol Clin 1993, 23:47-60. URL

    Assa-Munt, N., Mortishire-Smith, R. J., Aurora, R., Herr, W., Wright, P. E.: The solution structure of the Oct-1 POU-specific domain reveals a striking similarity to the bacteriophage lambda repressor DNA-binding domain. Cell 1993, 73:193-205. URL


1992

 

 
    Thorens, B., Wu, Y. J., Leahy, J. L., Weir, G. C.: The loss of GLUT2 expression by glucose-unresponsive beta cells of db/db mice is reversible and is induced by the diabetic environment. J Clin Invest 1992, 90:77-85. URL

    Thorens, B.: Molecular and cellular physiology of GLUT-2, a high-Km facilitated diffusion glucose transporter. Int Rev Cytol 1992, 137:209-38. URL

    Thorens, B.: Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1. Proc Natl Acad Sci U S A 1992, 89:8641-5. URL

    ten Heggeler-Bordier, B., Wahli, W., Adrian, M., Stasiak, A., Dubochet, J.: The apical localization of transcribing RNA polymerases on supercoiled DNA prevents their rotation around the template. Embo J 1992, 11:667-72. URL

    Tanaka, M., Lai, J. S., Herr, W.: Promoter-selective activation domains in Oct-1 and Oct-2 direct differential activation of an snRNA and mRNA promoter. Cell 1992, 68:755-67. URL

    Tal, M., Thorens, B., Surana, M., Fleischer, N., Lodish, H. F., Hanahan, D., Efrat, S.: Glucose transporter isotypes switch in T-antigen-transformed pancreatic beta cells growing in culture and in mice. Mol Cell Biol 1992, 12:422-32. URL

    Tafti, M., Villemin, E., Carlander, B., Besset, A., Billiard, M.: Sleep in human narcolepsy revisited with special reference to prior wakefulness duration. Sleep 1992, 15:344-51. URL

    Tafti, M., Villemin, E., Carlander, B., Besset, A., Billiard, M.: Sleep onset rapid-eye-movement episodes in narcolepsy: REM sleep pressure or nonREM-REM sleep dysregulation?. J Sleep Res 1992, 1:245-250. URL

    Tafti, M., Rondouin, G., Besset, A., Billiard, M.: Sleep deprivation in narcoleptic subjects: effect on sleep stages and EEG power density. Electroencephalogr Clin Neurophysiol 1992, 83:339-49. URL

    Tafti, M., Besset, A., Billiard, M.: Effects of zopiclone on subjective evaluation of sleep and daytime alertness and on psychomotor and physical performance tests in athletes. Prog Neuropsychopharmacol Biol Psychiatry 1992, 16:55-63. URL

    Stasiak, A.: Three-stranded DNA structure; is this the secret of DNA homologous recognition?. Mol Microbiol 1992, 6:3267-76. URL

    Reymond, A., Schmidt, S., Simanis, V.: Mutations in the cdc10 start gene of Schizosaccharomyces pombe implicate the region of homology between cdc10 and SWI6 as important for p85cdc10 function. Mol Gen Genet 1992, 234:449-56. URL

    Polo, O., Tafti, M., Hamalainen, M., Vaahtoranta, K., Alihanka, J.: Respiratory variation of the ballistocardiogram during increased respiratory load and voluntary central apnoea. Eur Respir J 1992, 5:257-62. URL

    Phares, W., Franza, B. R., Jr., Herr, W.: The kappa B enhancer motifs in human immunodeficiency virus type 1 and simian virus 40 recognize different binding activities in human Jurkat and H9 T cells: evidence for NF-kappa B-independent activation of the kappa B motif. J Virol 1992, 66:7490-8. URL

    Ourednik, W, Wahli, W., Van der Loos, H: The developing mouse whiskerpad : pattern formation at the periphery of a highly organized somatosensory pathway In Development of the Central Nervous System in Vertebrates Volume 234. Edited by S.C. Sharma and A.M. Goffinet, NATO ASI SERIES; Plenum Press; 1992: 145-165.

    Michalik, L., Vanier, M. T., Launay, J. F.: Characterization of a 67 kDa microtubule-binding protein in the pancreas from different species. Biochim Biophys Acta 1992, 1116:269-73. URL

    Marks, J., Fankhauser, C., Simanis, V.: Genetic interactions in the control of septation in Schizosaccharomyces pombe. J Cell Sci 1992, 101 ( Pt 4):801-8. URL

    Marks, J., Fankhauser, C., Reymond, A., Simanis, V.: Cytoskeletal and DNA structure abnormalities result from bypass of requirement for the cdc10 start gene in the fission yeast Schizosaccharomyces pombe. J Cell Sci 1992, 101 ( Pt 3):517-28. URL

    Lobo, S. M., Tanaka, M., Sullivan, M. L., Hernandez, N.: A TBP complex essential for transcription from TATA-less but not TATA-containing RNA polymerase III promoters is part of the TFIIIB fraction. Cell 1992, 71:1029-40. URL

    Lai, J. S., Herr, W.: Ethidium bromide provides a simple tool for identifying genuine DNA-independent protein associations. Proc Natl Acad Sci U S A 1992, 89:6958-62. URL

    Lai, J. S., Cleary, M. A., Herr, W.: A single amino acid exchange transfers VP16-induced positive control from the Oct-1 to the Oct-2 homeo domain. Genes Dev 1992, 6:2058-65. URL

    Herr, W.: Oct-1 and Oct-2: Differential transcriptional regulation by proteins that bind to the same DNA sequence In Transcriptional Regulation Edited by McKnight, SL,, Yamamoto, KR; Cold Spring Harbor Laboratory Press; 1992:

    Hernandez, N. : Transcription of snRNA genes and related genes In Transcriptional regulation Edited by Yamamoto, K.R., McKnight, S.L. ; Cold Spring Harbor; 1992: 281-283.

    Furrer, P., Bednar, S., Adrian, M., Stasiak, A., Dubochet, J., Révet, B., Brahms, S., Brahms, G.J.: Towards the direct determination of the shape of DNA molecules in solution. In Structure and Function : Nucleic Acids Volume Vol.1. Edited by Sarma, R.H. , Sarma, M.H. ; Adenine Press, Inc.; 1992: 229-236.

    Farsetti, A., Desvergne, B., Hallenbeck, P., Robbins, J., Nikodem, V. M.: Characterization of myelin basic protein thyroid hormone response element and its function in the context of native and heterologous promoter. J Biol Chem 1992, 267:15784-8. URL

    Dubochet, J., Adrian, M., Dustin, I., Furrer, P., Stasiak, A.: Cryoelectron microscopy of DNA molecules in solution. Methods Enzymol 1992, 211:507-18. URL

    Dubochet, J., Adrian, M., Bednar, J., Stasiak, A.: Seeing DNA in action In Electron Microscopy : Biological Sciences Volume 3. Edited by Megias, L. , Rodrigez-Garcia, M.I. , Rios, A. , Arias, J.M. ; Granada: University of Granada; 1992: 5-8.

    Dreyer, C., Krey, G., Keller, H., Givel, F., Helftenbein, G., Wahli, W.: Control of the peroxisomal beta-oxidation pathway by a novel family of nuclear hormone receptors. Cell 1992, 68:879-87. URL

    Courtot, C., Fankhauser, C., Simanis, V., Lehner, C. F.: The Drosophila cdc25 homolog twine is required for meiosis. Development 1992, 116:405-16. URL

    Chen, C., Thorens, B., Bonner-Weir, S., Weir, G. C., Leahy, J. L.: Recovery of glucose-induced insulin secretion in a rat model of NIDDM is not accompanied by return of the B-cell GLUT2 glucose transporter. Diabetes 1992, 41:1320-7. URL

    Boillat, M. A., Thorens, B.: [Acro-syndromes and occupational diseases: epidemiology and prevention of disease due to vibrating equipment]. Rev Med Suisse Romande 1992, 112:405-7. URL

    Aurora, R., Herr, W.: Segments of the POU domain influence one another's DNA-binding specificity. Mol Cell Biol 1992, 12:455-67. URL

    Aghayan, M., Rao, L. V., Smith, R. M., Jarett, L., Charron, M. J., Thorens, B., Heyner, S.: Developmental expression and cellular localization of glucose transporter molecules during mouse preimplantation development. Development 1992, 115:305-12. URL


1991

 

 
    Zhang, R., Alper, S. L., Thorens, B., Verkman, A. S.: Evidence from oocyte expression that the erythrocyte water channel is distinct from band 3 and the glucose transporter. J Clin Invest 1991, 88:1553-8. URL

    Wahli, W., Martinez, E.: Superfamily of steroid nuclear receptors: positive and negative regulators of gene expression. Faseb J 1991, 5:2243-9. URL

    Thorens, B.: [Accident insurance, CNA and medical corps]. Rev Med Suisse Romande 1991, 111:933-6. URL

    ten Heggeler-Bordier, B., Wahli, W.: Electron microscopy visualization of protein-DNA complexes In A Laboratory Guide to In Vitro Studies of Protein-DNA Interactions Volume 5. Edited by Birkhäuser, BioMethods ; Basel, Boston, Berlin: 1991: 153-161.

    Stern, S., Herr, W.: The herpes simplex virus trans-activator VP16 recognizes the Oct-1 homeo domain: evidence for a homeo domain recognition subdomain. Genes Dev 1991, 5:2555-66. URL

    Stasiak, A. Z., Rosselli, W., Stasiak, A.: RecA-DNA helical filaments in genetic recombination. Biochimie 1991, 73:199-208. URL

    Rosselli, W., Stasiak, A.: The ATPase activity of RecA is needed to push the DNA strand exchange through heterologous regions. Embo J 1991, 10:4391-6. URL

    Polo, O. J., Tafti, M., Fraga, J., Porkka, K. V., Dejean, Y., Billiard, M.: Why don't all heavy snorers have obstructive sleep apnea?. Am Rev Respir Dis 1991, 143:1288-93. URL

    Phares, W., Herr, W.: Functional similarities between human immunodeficiency virus type 1 and simian virus 40 kappa B proto-enhancers. J Virol 1991, 65:2200-10. URL

    Ondek, B., Herr, W.: Stable growth of simian virus 40 recombinants containing multimerized enhancers. J Virol 1991, 65:1596-9. URL

    Muller, B., Stasiak, A.: RecA-mediated annealing of single-stranded DNA and its relation to the mechanism of homologous recombination. J Mol Biol 1991, 221:131-45. URL

    Michalik, L., Vanier, M. T., Launay, J. F.: Microtubule affinity chromatography: a new technique for isolating microtubule-binding proteins from rat pancreas. Cell Mol Biol 1991, 37:805-11. URL

    Martinez, E., Wahli, W.: Characterization of hormone response elements In Nuclear Hormone Receptors Edited by M.G. Parker ; London: Academic Press; 1991: 125-153.

    Martinez, E., Givel, F., Wahli, W.: A common ancestor DNA motif for invertebrate and vertebrate hormone response elements. Embo J 1991, 10:263-8. URL

    Martinez, E., Dusserre, Y., Wahli, W., Mermod, N.: Synergistic transcriptional activation by CTF/NF-I and the estrogen receptor involves stabilized interactions with a limiting target factor. Mol Cell Biol 1991, 11:2937-45. URL

    Lobo, S. M., Lister, J., Sullivan, M. L., Hernandez, N.: The cloned RNA polymerase II transcription factor IID selects RNA polymerase III to transcribe the human U6 gene in vitro. Genes Dev 1991, 5:1477-89. URL

    Lebeau, M. C., Alvarez-Bolado, G., Wahli, W., Catsicas, S.: PCR driven DNA-DNA competitive hybridization: a new method for sensitive differential cloning. Nucleic Acids Res 1991, 19:4778. URL

    Lebeau, M. C., Alvarez-Bolado, G., Braissant, O., Wahli, W., Catsicas, S.: Ribosomal protein L27 is identical in chick and rat. Nucleic Acids Res 1991, 19:1337. URL

    Hogan, A., Heyner, S., Charron, M. J., Copeland, N. G., Gilbert, D. J., Jenkins, N. A., Thorens, B., Schultz, G. A.: Glucose transporter gene expression in early mouse embryos. Development 1991, 113:363-72. URL

    Herr, W.: Gene activation. An agent of suppression. Nature 1991, 350:554-5. URL

    Herr, W.: Regulation of eukaryotic RNA polymerase II transcription by sequence-specific DNA-binding proteins In The Hormonal Control of Gene Expression Edited by Cohen, P, and Foulkes, J.G.; 1991: 25-56.

    Hacker, H. J., Thorens, B., Grobholz, R.: Expression of facilitative glucose transporter in rat liver and choroid plexus. A histochemical study in native cryostat sections. Histochemistry 1991, 96:435-9. URL

    Farsetti, A., Mitsuhashi, T., Desvergne, B., Robbins, J., Nikodem, V. M.: Molecular basis of thyroid hormone regulation of myelin basic protein gene expression in rodent brain. J Biol Chem 1991, 266:23226-32. URL

    Fankhauser, C., Izaurralde, E., Adachi, Y., Wingfield, P., Laemmli, U. K.: Specific complex of human immunodeficiency virus type 1 rev and nucleolar B23 proteins: dissociation by the Rev response element. Mol Cell Biol 1991, 11:2567-75. URL

    Dustin, I., Furrer, P., Stasiak, A., Dubochet, J., Langowski, J., Egelman, E.: Spatial visualization of DNA in solution. J Struct Biol 1991, 107:15-21. URL

    Desvergne, B., Petty, K. J., Nikodem, V. M.: Functional characterization and receptor binding studies of the malic enzyme thyroid hormone response element. J Biol Chem 1991, 266:1008-13. URL

    Corthesy, B., Corthesy-Theulaz, I., Cardinaux, J. R., Wahli, W.: A liver protein fraction regulating hormone-dependent in vitro transcription from the vitellogenin genes induces their expression in Xenopus oocytes. Mol Endocrinol 1991, 5:159-69. URL


1990

 

 
    Valmier, J., Tafti, M., Baldy-Moulinier, M.: Skeletal muscle extracts promote the survival of neurofilament-positive mammalian sensory neurons. Neurosci Lett 1990, 114:39-44. URL

    Thorens, B., Weir, G. C., Leahy, J. L., Lodish, H. F., Bonner-Weir, S.: Reduced expression of the liver/beta-cell glucose transporter isoform in glucose-insensitive pancreatic beta cells of diabetic rats. Proc Natl Acad Sci U S A 1990, 87:6492-6. URL

    Thorens, B., Lodish, H. F., Brown, D.: Differential localization of two glucose transporter isoforms in rat kidney. Am J Physiol 1990, 259:C286-94. URL

    Thorens, B., Flier, J. S., Lodish, H. F., Kahn, B. B.: Differential regulation of two glucose transporters in rat liver by fasting and refeeding and by diabetes and insulin treatment. Diabetes 1990, 39:712-9. URL

    Thorens, B., Cheng, Z. Q., Brown, D., Lodish, H. F.: Liver glucose transporter: a basolateral protein in hepatocytes and intestine and kidney cells. Am J Physiol 1990, 259:C279-85. URL

    Thorens, B., Charron, M. J., Lodish, H. F.: Molecular physiology of glucose transporters. Diabetes Care 1990, 13:209-18. URL

    Theulaz, I., Wahli, W.: Preparation of nuclear extract from Xenopus oocytes injected with an expression vector encoding a transcription factor and functional analysis of the newly synthesized protein. DNA and Protein Engineering Techniques 1990, 2:65-68.

    Tanaka, M., Herr, W.: Differential transcriptional activation by Oct-1 and Oct-2: interdependent activation domains induce Oct-2 phosphorylation. Cell 1990, 60:375-86. URL

    Tal, M., Schneider, D. L., Thorens, B., Lodish, H. F.: Restricted expression of the erythroid/brain glucose transporter isoform to perivenous hepatocytes in rats. Modulation by glucose. J Clin Invest 1990, 86:986-92. URL

    Rosselli, W., Stasiak, A.: Energetics of RecA-mediated recombination reactions. Without ATP hydrolysis RecA can mediate polar strand exchange but is unable to recycle. J Mol Biol 1990, 216:335-52. URL

    Ratnasabapathy, R., Sheldon, M., Johal, L., Hernandez, N.: The HIV-1 long terminal repeat contains an unusual element that induces the synthesis of short RNAs from various mRNA and snRNA promoters. Genes Dev 1990, 4:2061-74. URL

    Petty, K. J., Desvergne, B., Mitsuhashi, T., Nikodem, V. M.: Identification of a thyroid hormone response element in the malic enzyme gene. J Biol Chem 1990, 265:7395-400. URL

    Orci, L., Unger, R. H., Ravazzola, M., Ogawa, A., Komiya, I., Baetens, D., Lodish, H. F., Thorens, B.: Reduced beta-cell glucose transporter in new onset diabetic BB rats. J Clin Invest 1990, 86:1615-22. URL

    Nikodem, V. M., Petty, K. J., Mitsuhashi, T., Desvergne, B.: Structure and mechanism of action of thyroid hormone receptors In The Thyroid Gland Edited by Greer MA; New-York: Raven Press; 1990: 307-321.

    Muller, B., Koller, T., Stasiak, A.: Characterization of the DNA binding activity of stable RecA-DNA complexes. Interaction between the two DNA binding sites within RecA helical filaments. J Mol Biol 1990, 212:97-112. URL

    Lobo, S. M., Ifill, S., Hernandez, N.: cis-acting elements required for RNA polymerase II and III transcription in the human U2 and U6 snRNA promoters. Nucleic Acids Res 1990, 18:2891-9. URL

    Johnson, J. H., Newgard, C. B., Milburn, J. L., Lodish, H. F., Thorens, B.: The high Km glucose transporter of islets of Langerhans is functionally similar to the low affinity transporter of liver and has an identical primary sequence. J Biol Chem 1990, 265:6548-51. URL

    Hsieh, C. L., Sturm, R., Herr, W., Francke, U.: The gene for the ubiquitous octamer-binding protein Oct-1 is on human chromosome 1, region cen-q32, and near Ly-22 and Ltw-4 on mouse chromosome 1. Genomics 1990, 6:666-72. URL

    Corthesy, B., Wahli, W.: A protocol for the preparation of nuclear extracts capable of estrogen-dependent in vitro transcription.. DNA and Protein Engineering Techniques 1990, 2:68-71.

    Corthesy, B., Leonnard, P., Wahli, W.: Transcriptional potentiation of the vitellogenin B1 promoter by a combination of both nucleosome assembly and transcription factors: an in vitro dissection. Mol Cell Biol 1990, 10:3926-33. URL

    Corthesy, B., Claret, F. X., Wahli, W.: Estrogen receptor level determines sex-specific in vitro transcription from the Xenopus vitellogenin promoter. Proc Natl Acad Sci U S A 1990, 87:7878-82. URL

    Adrian, M., ten Heggeler-Bordier, B., Wahli, W., Stasiak, A. Z., Stasiak, A., Dubochet, J.: Direct visualization of supercoiled DNA molecules in solution. Embo J 1990, 9:4551-4. URL


1989

 

 
    Wahli, W., Martinez, E., Corthesy, B., Cardinaux, J. R.: cis- and trans-acting elements of the estrogen-regulated vitellogenin gene B1 of Xenopus laevis. J Steroid Biochem 1989, 34:17-32. URL

    Tremea, F., Batistuzzo de Medeiros, S. R., ten Heggeler-Bordier, B., Germond, J. E., Seiler-Tuyns, A., Wahli, W.: Identification of two steroid-responsive promoters of different strength controlled by the same estrogen-responsive element in the 5'-end region of the Xenopus laevis vitellogenin gene A1. Mol Endocrinol 1989, 3:1596-609. URL

    Tafti, M., Verge, M., Besset, A., Billiard, M.: [A world record in marathon tennis: sleep deprivation and performance]. C R Seances Soc Biol Fil 1989, 183:474-81. URL

    Suzue, K., Lodish, H. F., Thorens, B.: Sequence of the mouse liver glucose transporter. Nucleic Acids Res 1989, 17:10099. URL

    Stern, S., Tanaka, M., Herr, W.: The Oct-1 homoeodomain directs formation of a multiprotein-DNA complex with the HSV transactivator VP16. Nature 1989, 341:624-30. URL

    Stasiak, A., Weber, C., Dubochet, J.: DNA helical repeats. Nature 1989, 338:24. URL

    Orci, L., Thorens, B., Ravazzola, M., Lodish, H. F.: Localization of the pancreatic beta cell glucose transporter to specific plasma membrane domains. Science 1989, 245:295-7. URL

    Martinez, E., Wahli, W.: Cooperative binding of estrogen receptor to imperfect estrogen-responsive DNA elements correlates with their synergistic hormone-dependent enhancer activity. Embo J 1989, 8:3781-91. URL

    Lobo, S. M., Hernandez, N.: A 7 bp mutation converts a human RNA polymerase II snRNA promoter into an RNA polymerase III promoter. Cell 1989, 58:55-67. URL

    Lescoat, G., Jouanolle, H., Desvergne, B., Pasdeloup, N., Kneip, B., Deugnier, Y., Guillouzo, A., Brissot, P.: Effects of iron overload on transferrin secretion by cultured fetal rat hepatocytes. Biol Cell 1989, 65:221-9. URL

    Lescoat, G., Desvergne, B., Loreal, O., Pasdeloup, N., Deugnier, Y., Bourel, M., Brissot, P.: Modulation of albumin secretion by ornithine alpha-ketoglutarate in adult rat hepatocyte cultures and a human hepatoma cell line (HepG2). Ann Nutr Metab 1989, 33:252-60. URL

    Haefliger, D. N., Moskaitis, J. E., Schoenberg, D. R., Wahli, W.: Amphibian albumins as members of the albumin, alpha-fetoprotein, vitamin D-binding protein multigene family. J Mol Evol 1989, 29:344-54. URL

    Desvergne, B., Baffet, G., Loyer, P., Rissel, M., Lescoat, G., Guguen-Guillouzo, C., Brissot, P.: Chronic iron overload inhibits protein secretion by adult rat hepatocytes maintained in long-term primary culture. Eur J Cell Biol 1989, 49:162-70. URL

    Corthesy, B., Cardinaux, J. R., Claret, F. X., Wahli, W.: A nuclear factor I-like activity and a liver-specific repressor govern estrogen-regulated in vitro transcription from the Xenopus laevis vitellogenin B1 promoter. Mol Cell Biol 1989, 9:5548-62. URL

    Collart, M. A., Belin, D., Briottet, C., Thorens, B., Vassalli, J. D., Vassalli, P.: Receptor-mediated phagocytosis by macrophages induces a calcium-dependent transient increase in c-fos transcription. Oncogene 1989, 4:237-41. URL

    Amrein, M., Durr, R., Stasiak, A., Gross, H., Travaglini, G.: Scanning tunneling microscopy of uncoated recA-DNA complexes. Science 1989, 243:1708-11. URL


1988

 

 
    Wahli, W., Seiler-Tuyns, A., Theulaz, I., Corthesy, B.: Mise en activité sélective d'un gène par une hormone. UNI Lausanne 1988, 54:22-25.

    Wahli, W.: Evolution and expression of vitellogenin genes. Trends Genet 1988, 4:227-32. URL

    Wahli, W.: Le génie génétique et les biotechnologies au service de l'homme. Semailles et moissons 1988, 100:8-12.

    Wahli, W.: La vie : objet de laboratoire ?. Actes 1988, 83:6-11.

    Travaglini, G., Stoll, G., Amrein, M., Stasiak, A., Gross, H.: Scanning and tunnelling microscopy of Rec-A-DNA complexes.. Journal de Microscopie et de Spectroscopie Electroniques 1988, 13:257-264.

    Travaglini, G., Roher, H., Stoll, E., Amrein, M., Stasiak, A., Sogo, J., Gross, H.: Scanning tunneling microscopy of RecA-DNA complexes and DNA. Physica Scripta 1988, 38:309-314.

    Thorens, B., Sarkar, H. K., Kaback, H. R., Lodish, H. F.: Cloning and functional expression in bacteria of a novel glucose transporter present in liver, intestine, kidney, and beta-pancreatic islet cells. Cell 1988, 55:281-90. URL

    Theulaz, I., Hipskind, R., ten Heggeler-Bordier, B., Green, S., Kumar, V., Chambon, P., Wahli, W.: Expression of human estrogen receptor mutants in Xenopus oocytes: correlation between transcriptional activity and ability to form protein-DNA complexes. Embo J 1988, 7:1653-60. URL

    ten Heggler-Bordier, B., Claret, F. X., Wahli, W.: Immuno-electron microscopic identification of human estrogen receptor-DNA complexes at the estrogen-responsive element and in the first intron of a Xenopus vitellogenin gene. J Mol Biol 1988, 204:217-20. URL

    Tanaka, M., Grossniklaus, U., Herr, W., Hernandez, N.: Activation of the U2 snRNA promoter by the octamer motif defines a new class of RNA polymerase II enhancer elements. Genes Dev 1988, 2:1764-78. URL

    Sturm, R. A., Herr, W.: The POU domain is a bipartite DNA-binding structure. Nature 1988, 336:601-4. URL

    Sturm, R. A., Das, G., Herr, W.: The ubiquitous octamer-binding protein Oct-1 contains a POU domain with a homeo box subdomain. Genes Dev 1988, 2:1582-99. URL

    Stasiak, A., Koller, Th.: Analysis of DNA knots and catenanes allows to deduce the mechanism of action of enzymes which cut and join DNA strands. In New theoretical concepts in physical chemistry. NATO ASI Series, Fractals, Quasicristals, Chaos, Knots and Algebraic Quantum Mechanics Edited by Amann, A. , Cederbaum, L.S. , Gans, W. ; Dordrecht: Kluwer Academic Publishers; 1988: 207-219.

    Stasiak, A., Egelman, E. H., Howard-Flanders, P.: Structure of helical RecA-DNA complexes. III. The structural polarity of RecA filaments and functional polarity in the RecA-mediated strand exchange reaction. J Mol Biol 1988, 202:659-62. URL

    Stasiak, A., Egelman, E.H.: Visualization of recombination intermediates. In Genetic Recombination Edited by R. Kucherlapati, G.R. Smith; Washington DC: American Society for Microbiology; 1988: 265-307.

    Shepard, A., Clarke, J., Herr, W.: Simian virus 40 revertant enhancers exhibit restricted host ranges for enhancer function. J Virol 1988, 62:3364-70. URL

    Shapiro, D. J., Sharp, P. A., Wahli, W. W., Keller, M. J.: A high-efficiency HeLa cell nuclear transcription extract. DNA 1988, 7:47-55. URL

    Seiler-Tuyns, A., Merillat, A. M., Haefliger, D. N., Wahli, W.: The human estrogen receptor can regulate exogenous but not endogenous vitellogenin gene promoters in a Xenopus cell line. Nucleic Acids Res 1988, 16:8291-305. URL

    Sarkar, H. K., Thorens, B., Lodish, H. F., Kaback, H. R.: Expression of the human erythrocyte glucose transporter in Escherichia coli. Proc Natl Acad Sci U S A 1988, 85:5463-7. URL

    Ondek, B., Gloss, L., Herr, W.: The SV40 enhancer contains two distinct levels of organization. Nature 1988, 333:40-5. URL

    Lescoat, G., Loreal, O., Desvergne, B., Pasdeloup, N., Deugnier, Y., Brissot, P.: Effect of ornithine on transferrin secretion of rat and human hepatocyte cultures. Liver 1988, 8:360-5. URL

    Herr, W., Sturm, R. A., Clerc, R. G., Corcoran, L. M., Baltimore, D., Sharp, P. A., Ingraham, H. A., Rosenfeld, M. G., Finney, M., Ruvkun, G., et al.,: The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products. Genes Dev 1988, 2:1513-6. URL

    Hernandez, N., Lucito, R.: Elements required for transcription initiation of the human U2 snRNA gene coincide with elements required for snRNA 3' end formation. Embo J 1988, 7:3125-34. URL

    Green, S., Kumar, V., Theulaz, I., Wahli, W., Chambon, P.: The N-terminal DNA-binding 'zinc finger' of the oestrogen and glucocorticoid receptors determines target gene specificity. Embo J 1988, 7:3037-44. URL

    Etienne, P. L., Baffet, G., Desvergne, B., Boisnard-Rissel, M., Glaise, D., Guguen-Guillouzo, C.: Transient expression of c-fos and constant expression of c-myc in freshly isolated and cultured normal adult rat hepatocytes. Oncogene Res 1988, 3:255-62. URL

    Eliason, J. F., Thorens, B., Kindler, V., Vassalli, P.: The roles of granulocyte-macrophage colony-stimulating factor and interleukin 3 in stromal cell-mediated hemopoiesis in vivo. Exp Hematol 1988, 16:307-12. URL

    Egelman, E. H., Stasiak, A.: Structure of helical RecA-DNA complexes. II. Local conformational changes visualized in bundles of RecA-ATP gamma S filaments. J Mol Biol 1988, 200:329-49. URL

    Corthesy, B., Hipskind, R., Theulaz, I., Wahli, W.: Estrogen-dependent in vitro transcription from the vitellogenin promoter in liver nuclear extracts. Science 1988, 239:1137-9. URL

    Baumruker, T., Sturm, R., Herr, W.: OBP100 binds remarkably degenerate octamer motifs through specific interactions with flanking sequences. Genes Dev 1988, 2:1400-13. URL

    Amrein, M., Stasiak, A., Gross, H., Stoll, E., Travaglini, G.: Scanning tunneling microscopy of recA-DNA complexes coated with a conducting film. Science 1988, 240:514-6. URL


1987

 

 
    Thorens, B., Mermod, J. J., Vassalli, P.: Phagocytosis and inflammatory stimuli induce GM-CSF mRNA in macrophages through posttranscriptional regulation. Cell 1987, 48:671-9. URL

    ten Heggeler-Bordier, B., Hipskind, R., Seiler-Tuyns, A., Martinez, E., Corthesy, B., Wahli, W.: Electron microscopic visualization of protein-DNA interactions at the estrogen responsive element and in the first intron of the Xenopus laevis vitellogenin gene. Embo J 1987, 6:1715-20. URL

    Sturm, R., Baumruker, T., Franza, B. R., Jr., Herr, W.: A 100-kD HeLa cell octamer binding protein (OBP100) interacts differently with two separate octamer-related sequences within the SV40 enhancer. Genes Dev 1987, 1:1147-60. URL

    Stasiak, A., Egelman, E.H.: RecAprotein DNA interactions in recombination In Mechanisms of DNA replication and recombination. Edited by T. Kelly , R. McMacken; New-York: Alan R. Liss Inc.; 1987: 619-629.

    Sogo, J., Stasiak, A., DeBernardin, W., Losa, R., Koller, Th.: Binding of proteins to nucleic acids as studied by electron microscopy In Electron Microscopy in Molecular Biology Edited by J. Sommerville , U. Sheer; Oxford: IRL Press; 1987: 61-79.

    Ondek, B., Shepard, A., Herr, W.: Discrete elements within the SV40 enhancer region display different cell-specific enhancer activities. Embo J 1987, 6:1017-25. URL

    Nardelli, D., van het Schip, F. D., Gerber-Huber, S., Haefliger, J. A., Gruber, M., Ab, G., Wahli, W.: Comparison of the organization and fine structure of a chicken and a Xenopus laevis vitellogenin gene. J Biol Chem 1987, 262:15377-85. URL

    Nardelli, D., Gerber-Huber, S., van het Schip, F. D., Gruber, M., Ab, G., Wahli, W.: Vertebrate and nematode genes coding for yolk proteins are derived from a common ancestor. Biochemistry 1987, 26:6397-402. URL

    Martinez, E., Givel, F., Wahli, W.: The estrogen-responsive element as an inducible enhancer: DNA sequence requirements and conversion to a glucocorticoid-responsive element. Embo J 1987, 6:3719-27. URL

    Kindler, V., Thorens, B., Vassalli, P.: In vivo effect of murine recombinant interleukin 3 on early hemopoietic progenitors. Eur J Immunol 1987, 17:1511-4. URL

    Jouanolle, H., Lescoat, G., Desvergne, B., Deugnier, Y., Brissot, P., Bourel, M.: [Iron overload of the liver and protein synthesis. Progress made through experimental models]. Ann Gastroenterol Hepatol (Paris) 1987, 23:269-72. URL

    Howard-Flanders, P., West, S.C., Cassuto, E., Hahn, T., Egelman, E.H., Stasiak, A.: Structure of RecA spiral filaments and their role in homologous pairing and strand exchange in genetic recombination. In Mechanisms of DNA replication and recombination Edited by Kelly, T. , McMacken, R. ; New-York: Alan R. Liss Inc.; 1987: 609-617.

    Haefliger, J. A., Tschopp, J., Nardelli, D., Wahli, W., Kocher, H. P., Tosi, M., Stanley, K. K.: Complementary DNA cloning of complement C8 beta and its sequence homology to C9. Biochemistry 1987, 26:3551-6. URL

    Gerber-Huber, S., Nardelli, D., Haefliger, J. A., Cooper, D. N., Givel, F., Germond, J. E., Engel, J., Green, N. M., Wahli, W.: Precursor-product relationship between vitellogenin and the yolk proteins as derived from the complete sequence of a Xenopus vitellogenin gene. Nucleic Acids Res 1987, 15:4737-60. URL

    Cooper, D. N., Gerber-Huber, S., Nardelli, D., Schubiger, J. L., Wahli, W.: The distribution of the dinucleotide CpG and cytosine methylation in the vitellogenin gene family. J Mol Evol 1987, 25:107-15. URL

    Clarke, J., Herr, W.: Activation of mutated simian virus 40 enhancers by amplification of wild-type enhancer elements. J Virol 1987, 61:3536-42. URL

    Brissot, P., Farjanel, J., Bourel, D., Campion, J. P., Guillouzo, A., Rattner, A., Deugnier, Y., Desvergne, B., Ferrand, B., Simon, M., et al.,: Chronic liver iron overload in the baboon by ferric nitrilotriacetate. Morphologic and functional changes with special reference to collagen synthesis enzymes. Dig Dis Sci 1987, 32:620-7. URL


1986

 

 
    Thorens, B., Vassalli, P.: Chloroquine and ammonium chloride prevent terminal glycosylation of immunoglobulins in plasma cells without affecting secretion. Nature 1986, 321:618-20. URL

    Stasiak, A., Egelman, E.H.: Structure and dynamics of RecA protein-DNA complexes as determined by image analysis of electron micrographs. Biophysical Journal 1986, 49:5-7.

    Stasiak, A., Egelman, E. H.: RecA-DNA helical complexes in genetic recombination. Biochem Soc Trans 1986, 14:218-20. URL

    Seiler-Tuyns, A., Walker, P., Martinez, E., Merillat, A. M., Givel, F., Wahli, W.: Identification of estrogen-responsive DNA sequences by transient expression experiments in a human breast cancer cell line. Nucleic Acids Res 1986, 14:8755-70. URL

    Schubiger, J. L., Wahli, W.: Linkage arrangement in the vitellogenin gene family of Xenopus laevis as revealed by gene segregation analysis. Nucleic Acids Res 1986, 14:8723-34. URL

    Schubiger, J. L., Wahli, W.: Transposition of a bacterial IS3 element into a Xenopus Vi-element. Nucleic Acids Res 1986, 14:7814. URL

    Kindler, V., Thorens, B., de Kossodo, S., Allet, B., Eliason, J. F., Thatcher, D., Farber, N., Vassalli, P.: Stimulation of hematopoiesis in vivo by recombinant bacterial murine interleukin 3. Proc Natl Acad Sci U S A 1986, 83:1001-5. URL

    Herr, W., Clarke, J., Ondek, B., Shepard, A., Fox, H.: Duplications within mutated SV40 enhancers that restore enhancer function.. Cancer Cells 4/DNA Tumor Viruses 1986,
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    Herr, W.,, Clarke, J.,, Ondek, B.,, Shepard, A.,, Fox, H.: Duplications within mutated SV40 enhancers that restore enhancer function In Cancer Cells 4: DNA Tumor Viruses Edited by Botchan, M., , Grodzicker, T.,, Sharp, P. A.,; Cold Spring Harbor Laboratory Press; 1986: 95-101.

    Herr, W., Clarke, J.: The SV40 enhancer is composed of multiple functional elements that can compensate for one another. Cell 1986, 45:461-70. URL

    Hernandez, N., Weiner, A. M.: Formation of the 3' end of U1 snRNA requires compatible snRNA promoter elements. Cell 1986, 47:249-58. URL

    Egelman, E. H., Stasiak, A.: Structure of helical RecA-DNA complexes. Complexes formed in the presence of ATP-gamma-S or ATP. J Mol Biol 1986, 191:677-97. URL


1985

 

 
    Zoll, B., Arnemann, J., Krawczak, M., Cooper, D. N., Pescia, G., Wahli, W., Steinbach, P., Schmidtke, J.: Evidence against close linkage of the loci for fraXq of Martin-Bell syndrome and for factor IX. Hum Genet 1985, 71:122-6. URL

    Wahli, W., Ryffel, G. U.: Xenopus vitellogenin genes. Oxf Surv Eukaryot Genes 1985, 2:96-120. URL

    Thorens, B., Schulz, M. F., Vassalli, P.: Bone marrow pre-B lymphocytes synthesize immunoglobulin mu chains of membrane type with different properties and intracellular pathways. Embo J 1985, 4:361-8. URL

    ten Heggeler, B., Wahli, W.: Visualization of RNA polymerase II ternary transcription complexes formed in vitro on a Xenopus laevis vitellogenin gene. Embo J 1985, 4:2269-73. URL

    Spengler, S. J., Stasiak, A., Cozzarelli, N. R.: The stereostructure of knots and catenanes produced by phage lambda integrative recombination: implications for mechanism and DNA structure. Cell 1985, 42:325-34. URL

    Schubiger, J. L., Germond, J. E., ten Heggeler, B., Wahli, W.: The Vi element. A transposon-like repeated DNA sequence interspersed in the vitellogenin locus of Xenopus laevis. J Mol Biol 1985, 186:491-503. URL

    Herr, W., Gluzman, Y.: Duplications of a mutated simian virus 40 enhancer restore its activity. Nature 1985, 313:711-4. URL

    Herr, W.: Diethyl pyrocarbonate: a chemical probe for secondary structure in negatively supercoiled DNA. Proc Natl Acad Sci U S A 1985, 82:8009-13. URL

    Hernandez, N.: Formation of the 3' end of U1 snRNA is directed by a conserved sequence located downstream of the coding region. Embo J 1985, 4:1827-37. URL

    Dean, F. B., Stasiak, A., Koller, T., Cozzarelli, N. R.: Duplex DNA knots produced by Escherichia coli topoisomerase I. Structure and requirements for formation. J Biol Chem 1985, 260:4975-83. URL


1984

 

 
    Walker, P., Germond, J. E., Brown-Luedi, M., Givel, F., Wahli, W.: Sequence homologies in the region preceding the transcription initiation site of the liver estrogen-responsive vitellogenin and apo-VLDLII genes. Nucleic Acids Res 1984, 12:8611-26. URL

    Stasiak, A., Stasiak, A. Z., Koller, T.: Visualization of RecA-DNA complexes involved in consecutive stages of an in vitro strand exchange reaction. Cold Spring Harb Symp Quant Biol 1984, 49:561-70. URL

    Spengler, S. J., Stasiak, A., Stasiak, A. Z., Cozzarelli, N. R.: Quantitative analysis of the contributions of enzyme and DNA to the structure of lambda integrative recombinants. Cold Spring Harb Symp Quant Biol 1984, 49:745-9. URL

    Knowland, J., Theulaz, I., Wright, C. V., Wahli, W.: Injection of partially purified estrogen receptor protein from Xenopus liver nuclei into oocytes activates the silent vitellogenin locus. Proc Natl Acad Sci U S A 1984, 81:5777-81. URL

    Howard-Flanders, P., West, S. C., Stasiak, A.: Role of RecA protein spiral filaments in genetic recombination. Nature 1984, 309:215-9. URL

    Herr, W., Gilbert, W.: Free and integrated recombinant murine leukemia virus DNAs appear in preleukemic thymuses of AKR/J mice. J Virol 1984, 50:155-62. URL

    Herr, W.: Nucleotide sequence of AKV murine leukemia virus. J Virol 1984, 49:471-8. URL

    Germond, J. E., Walker, P., ten Heggeler, B., Brown-Luedi, M., de Bony, E., Wahli, W.: Evolution of vitellogenin genes: comparative analysis of the nucleotide sequences downstream of the transcription initiation site of four Xenopus laevis and one chicken gene. Nucleic Acids Res 1984, 12:8595-609. URL


1983

 

 
    Walker, P., Brown-Luedi, M., Germond, J. E., Wahli, W., Meijlink, F. C., van het Schip, A. D., Roelink, H., Gruber, M., Ab, G.: Sequence homologies within the 5' end region of the estrogen-controlled vitellogenin gene in Xenopus and chicken. Embo J 1983, 2:2271-9. URL

    Stasiak, A., DiCapua, E., Koller, T.: Unwinding of duplex DNA in complexes with recA protein. Cold Spring Harb Symp Quant Biol 1983, 47 Pt 2:811-20. URL

    Ryffel, G. U., Wahli, W.: Regulation and structure of the vitellogenin genes In Eucaryotic genes : Their structure, activity and regulation Edited by Butterworths; London: 1983: 329-341.

    Ryffel, G. U., Muellener, D. B., Gerber-Huber, S., Wyler, T., Wahli, W.: Scattering of repetitive DNA sequences in the albumin and vitellogenin gene loci of Xenopus laevis. Nucleic Acids Res 1983, 11:7701-16. URL

    Krasnow, M. A., Stasiak, A., Spengler, S. J., Dean, F., Koller, T., Cozzarelli, N. R.: Determination of the absolute handedness of knots and catenanes of DNA. Nature 1983, 304:559-60. URL

    Koller, Th, DiCapua, E, Stasiak, A: Complexes of RecA protein with single-stranded DNA. UCLA Symposia 10, Mechanism of DNA Replication and Recombination 1983, 10:723-729.

    Herr, W., Schwartz, D., Gilbert, W.: Isolation and mapping of cDNA hybridization probes specific for ecotropic and nonecotropic murine leukemia proviruses. Virology 1983, 125:139-54. URL

    Herr, W., Perlmutter, A. P., Gilbert, W.: Monoclonal AKR/J thymic leukemias contain multiple JH immunoglobulin gene rearrangements. Proc Natl Acad Sci U S A 1983, 80:7433-6. URL

    Herr, W., Gilbert, W.: Somatically acquired recombinant murine leukemia proviruses in thymic leukemias of AKR/J mice. J Virol 1983, 46:70-82. URL

    Hernandez, N., Keller, W.: Splicing of in vitro synthesized messenger RNA precursors in HeLa cell extracts. Cell 1983, 35:89-99. URL

    Germond, J. E., ten Heggeler, B., Schubiger, J. L., Walker, P., Westley, B., Wahli, W.: Vitellogenin B2 gene in Xenopus laevis: isolation, in vitro transcription and relation to other vitellogenin genes. Nucleic Acids Res 1983, 11:2979-97. URL

    Di Capua, E., Stasiak, A., Koller, T., Brahms, S., Thomae, R., Pohl, F. M.: Torsional stress induces left-handed helical stretches in DNA of natural base sequence: circular dichroism and antibody binding. Embo J 1983, 2:1531-5. URL

    Cattaneo, R., Will, H., Hernandez, N., Schaller, H.: Signals regulating hepatitis B surface antigen transcription. Nature 1983, 305:336-8. URL


1982

 

 
    Wahli, W., Germond, J. E., ten Heggeler, B., May, F. E.: Vitellogenin genes A1 and B1 are linked in the Xenopus laevis genome. Proc Natl Acad Sci U S A 1982, 79:6832-6. URL

    Wahli, W.: Analyses critiques de l'expression génétique. Dialectica 1982, 36:71-81.

    Thorens, B., Roth, J., Norman, A. W., Perrelet, A., Orci, L.: Immunocytochemical localization of the vitamin D-dependent calcium binding protein in chick duodenum. J Cell Biol 1982, 94:115-22. URL

    Stasiak, A., Di Capua, E.: The helicity of DNA in complexes with recA protein. Nature 1982, 299:185-6. URL

    Herr, W., Gilbert, W.: Germ-line MuLV reintegrations in AKR/J mice. Nature 1982, 296:865-8. URL

    Herr, W., Corbin, V., Gilbert, W.: Nucleotide sequence of the 3' half of AKV. Nucleic Acids Res 1982, 10:6931-44. URL

    Di Capua, E., Engel, A., Stasiak, A., Koller, T.: Characterization of complexes between recA protein and duplex DNA by electron microscopy. J Mol Biol 1982, 157:87-103. URL


1981

 

 
    Wahli, W., Dawid, I. B., Ryffel, G. U., Weber, R.: Vitellogenesis and the vitellogenin gene family. Science 1981, 212:298-304. URL

    Stasiak, A., Di Capua, E., Koller, T.: Elongation of duplex DNA by recA protein. J Mol Biol 1981, 151:557-64. URL

    Ryffel, G. U., Muellener, D. B., Wyler, T., Wahli, W., Weber, R.: Transcription of single-copy vitellogenin gene of Xenopus involves expression of middle repetitive DNA. Nature 1981, 291:429-31. URL

    Roth, J., Thorens, B., Hunziker, W., Norman, A. W., Orci, L.: Vitamin D--dependent calcium binding protein: immunocytochemical localization in chick kidney. Science 1981, 214:197-200. URL

    Peattie, D. A., Herr, W.: Chemical probing of the tRNA--ribosome complex. Proc Natl Acad Sci U S A 1981, 78:2273-7. URL

    Noller, H. F., Kop, J., Wheaton, V., Brosius, J., Gutell, R. R., Kopylov, A. M., Dohme, F., Herr, W., Stahl, D. A., Gupta, R., Waese, C. R.: Secondary structure model for 23S ribosomal RNA. Nucleic Acids Res 1981, 9:6167-89. URL


1980

 

 
    Wahli, W., Dawid, I. B., Wyler, T., Weber, R., Ryffel, G. U.: Comparative analysis of the structural organization of two closely related vitellogenin genes in X. laevis. Cell 1980, 20:107-17. URL

    Wahli, W., Dawid, I. B.: Isolation of two closely related vitellogenin genes, including their flanking regions, from a Xenopus laevis gene library. Proc Natl Acad Sci U S A 1980, 77:1437-41. URL

    Stasiak, A.: [Restriction enzymes. I. Mechanisms of action of type II restriction-modification systems (author's transl)]. Postepy Biochem 1980, 26:343-67. URL

    Stasiak, A.: [Restriction enzymes. II. Mechanisms of action of type I and III restriction-modyfication systems (author's transl)]. Postepy Biochem 1980, 26:369-87. URL

    Piekarowicz, A., Stasiak, A., Stanczak, J.: Specific restriction endonucleases from Haemophilus influenzae JC9. Acta Microbiol Pol 1980, 29:151-6. URL

    Felber, B. K., Maurhofer, S., Jaggi, R. B., Wyler, T., Wahli, W., Ryffel, G. U., Weber, R.: Isolation and translation in vitro of four related vitellogenin mRNAs of estrogen-stimulated Xenopus laevis. Eur J Biochem 1980, 105:17-24. URL

    Arcidiacono, A., Stasiak, A., Koller, Th., P. Brederoo, W. De Priester: Protein-free specimen preparation of nucleic acids and nucleic acid-protein complexes. Proceedings of the 7th European Congress on Electron Microscopy 1980, 2:516-525.


1979

 

 
    Wahli, W., Dawid, I. B., Wyler, T., Jaggi, R. B., Weber, R., Ryffel, G. U.: Vitellogenin in Xenopus laevis is encoded in a small family of genes. Cell 1979, 16:535-49. URL

    Stasiak, A., Klopotowski, T.: Four-stranded DNA structure and DNA base methylation in the mechanism of action of restriction endonucleases. J Theor Biol 1979, 80:65-82. URL

    Herr, W., Noller, H. F.: Protection of specific sites in 23 S and 5 S RNA from chemical modification by association of 30 S and 50 S ribosomes. J Mol Biol 1979, 130:421-32. URL

    Herr, W., Chapman, N. M., Noller, H. F.: Mechanism of ribosomal subunit association: discrimination of specific sites in 16 S RNA essential for association activity. J Mol Biol 1979, 130:433-49. URL

    Dawid, I. B., Wahli, W.: Application of recombinant DNA technology to questions of developmental biology: a review. Dev Biol 1979, 69:305-28. URL


1978

 

 
    Wahli, W., Wyler, T., Weber, R., Ryffel, G. U.: Electron-microscopic demonstration of terminal and internal initiation sites for cDNA synthesis on vitellogenin mRNA. Eur J Biochem 1978, 86:225-34. URL

    Wahli, W., Ryffel, G. U., Wyler, T., Jaggi, F. B., Weber, R., Dawid, I. B.: Cloning and characterization of synthetic sequences from the Xenopus iaevis vitellogenin structural gene. Dev Biol 1978, 67:371-83. URL

    Wahli, W., Abraham, I., Weber, R.: Retention of the differentiated state by larval Xenopus liver cells in primary culture. Wilhelm Roux's Archives 1978,
    235-248. URL

    Wahli, W.: The vitellogenin gene in Xenopus laevis In Carnegie Institution Year Book Volume 77. 1978: 95-103.

    Herr, W., Noller, H. F.: Nucleotide sequences of accessible regions of 23S RNA in 50S ribosomal subunits. Biochemistry 1978, 17:307-15. URL


1977

 

 
    Wahli, W. , Weber, R.: Factors promoting the establishment of primary cultures of liver cells from Xenopus larvae. Wilhelm Roux's Archives 1977,
    347-360. URL

    Wahli, W.: Untersuchungen über die Oestrogen-abhängige Synthese von Vitellogenin messenger RNA in der Leber von Xenopus laevis. 1977, Thesis:

    Ryffel, G. U., Wahli, W., Weber, R.: Quantitation of vitellogenin messenger RNA in the liver of male Xenopus toads during primary and secondary stimulation by estrogen. Cell 1977, 11:213-21. URL


1976

 

 
    Wahli, W., Wyler, T., Weber, R., Ryffel, G. U.: Size, complexity and abundance of a specific poly(A)-containing RNA of liver from male Xenopus induced to vitellogenin synthesis by estrogen. Eur J Biochem 1976, 66:457-65. URL


1975

 

 
    Herr, W., Noller, H. F.: A fragment of 23S RNA containing a nucleotide sequence complementary to a region of 5S RNA. FEBS Lett 1975, 53:248-52. URL


1974

 

 
    Noller, H. F., Herr, W.: Letters to the editor: Accessibility of 5 S RNA in 50 S ribosomal subunits. J Mol Biol 1974, 90:181-4. URL

    Noller, H. F., Herr, W.: Nucleotide sequence of the 3' terminus of E. coli 16S ribosomal RNA. Mol Biol Rep 1974, 1:437-9. URL

    Koller, F., Thorens, B., Riondel, A. M., Scholer, D.: [Proceedings: Cushing's syndrome in hypernephroid carcinoma; normalization of the cortisol value, hypokalemia and hypertension under metopirone]. Helv Med Acta 1974, 37:393-4. URL


1971

 

 
    Meyer, J. J., Rey, P., Thorens, B., Beaumanoir, A.: [Examination of subjects with craniocerebral trauma using a visual perception test: the de Lange curve]. Schweiz Arch Neurol Neurochir Psychiatr 1971, 108:213-21. URL
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