You are here: UNIL > Center for Integrative Genomics > Research > Research groups > Bernard Thorens > Publications


    Winnik, S., Gaul, D. S., Preitner, F., Lohmann, C., Weber, J., Miranda, M. X., Liu, Y., van Tits, L. J., Mateos, J. M., Brokopp, C. E., Auwerx, J., Thorens, B., Luscher, T. F., Matter, C. M.: Deletion of Sirt3 does not affect atherosclerosis but accelerates weight gain and impairs rapid metabolic adaptation in LDL receptor knockout mice: implications for cardiovascular risk factor development. Basic Res Cardiol 2014, 109:399. URL

    Vasu, S., Moffett, R. C., Thorens, B., Flatt, P. R.: Role of Endogenous GLP-1 and GIP in Beta Cell Compensatory Responses to Insulin Resistance and Cellular Stress. PLoS One 2014, 9:e101005. URL

    Tarussio, D., Metref, S., Seyer, P., Mounien, L., Vallois, D., Magnan, C., Foretz, M., Thorens, B.: Nervous glucose sensing regulates postnatal beta cell proliferation and glucose homeostasis. J Clin Invest 2014, 124:413-24. URL

    Roder, P. V., Geillinger, K. E., Zietek, T. S., Thorens, B., Koepsell, H., Daniel, H.: The Role of SGLT1 and GLUT2 in Intestinal Glucose Transport and Sensing. PLoS One 2014, 9:e89977. URL

    Moffett, R. C., Vasu, S., Thorens, B., Drucker, D. J., Flatt, P. R.: Incretin Receptor Null Mice Reveal Key Role of GLP-1 but Not GIP in Pancreatic Beta Cell Adaptation to Pregnancy. PLoS One 2014, 9:e96863. URL

    Lamy, C. M., Sanno, H., Labouebe, G., Picard, A., Magnan, C., Chatton, J. Y., Thorens, B.: Hypoglycemia-Activated GLUT2 Neurons of the Nucleus Tractus Solitarius Stimulate Vagal Activity and Glucagon Secretion. Cell Metab 2014, 19:527-38. URL

    Thorens, B.: The required beta cell research for improving treatment of type 2 diabetes. J Intern Med 2013, 274:203-14. URL

    Seyer, P., Vallois, D., Poitry-Yamate, C., Schutz, F., Metref, S., Tarussio, D., Maechler, P., Staels, B., Lanz, B., Grueter, R., Decaris, J., Turner, S., da Costa, A., Preitner, F., Minehira, K., Foretz, M., Thorens, B.: Hepatic glucose sensing is required to preserve beta cell glucose competence. J Clin Invest 2013, 123:1662-76. URL

    Preitner, F., Laverriere-Loss, A., Metref, S., Da Costa, A., Moret, C., Rotman, S., Bazin, D., Daudon, M., Sandt, C., Dessombz, A., Thorens, B.: Urate-induced acute renal failure and chronic inflammation in liver-specific Glut9 knockout mice. Am J Physiol Renal Physiol 2013, 305:F786-95. URL

    Mueckler, M., Thorens, B.: The SLC2 (GLUT) family of membrane transporters. Mol Aspects Med 2013, 34:121-38. URL

    Lengacher, S., Nehiri-Sitayeb, T., Steiner, N., Carneiro, L., Favrod, C., Preitner, F., Thorens, B., Stehle, J. C., Dix, L., Pralong, F., Magistretti, P. J., Pellerin, L.: Resistance to diet-induced obesity and associated metabolic perturbations in haploinsufficient monocarboxylate transporter 1 mice. PLoS One 2013, 8:e82505. URL

    Gaudin-Audrain, C., Irwin, N., Mansur, S., Flatt, P. R., Thorens, B., Basle, M., Chappard, D., Mabilleau, G.: Glucose-dependent insulinotropic polypeptide receptor deficiency leads to modifications of trabecular bone volume and quality in mice. Bone 2013, 53:221-30. URL

    Ding, J., Loizides-Mangold, U., Rando, G., Zoete, V., Michielin, O., Reddy, J. K., Wahli, W., Riezman, H., Thorens, B.: The Peroxisomal Enzyme L-PBE Is Required to Prevent the Dietary Toxicity of Medium-Chain Fatty Acids. Cell Rep 2013, 5:248-58. URL

    Deisl, C., Simonin, A., Anderegg, M., Albano, G., Kovacs, G., Ackermann, D., Moch, H., Dolci, W., Thorens, B., A. Hediger M, Fuster, D. G.: Sodium/hydrogen exchanger NHA2 is critical for insulin secretion in beta-cells. Proc Natl Acad Sci U S A 2013, 110:10004-9. URL

    Thorens, B.: Sensing of glucose in the brain. Handb Exp Pharmacol 2012, 209:277-94. URL

    Jimenez-Preitner, M., Berney, X., Thorens, B.: Plac8 is required for white adipocyte differentiation in vitro and cell number control in vivo. PLoS One 2012, 7:e48767. URL

    Jacovetti, C., Abderrahmani, A., Parnaud, G., Jonas, J. C., Peyot, M. L., Cornu, M., Laybutt, R., Meugnier, E., Rome, S., Thorens, B., Prentki, M., Bosco, D., Regazzi, R.: MicroRNAs contribute to compensatory beta cell expansion during pregnancy and obesity. J Clin Invest 2012, 122:3541-51. URL

    Iglesias, J., Barg, S., Vallois, D., Lahiri, S., Roger, C., Yessoufou, A., Pradevand, S., McDonald, A., Bonal, C., Reimann, F., Gribble, F., Debril, M. B., Metzger, D., Chambon, P., Herrera, P., Rutter, G. A., Prentki, M., Thorens, B., Wahli, W.: PPARbeta/delta affects pancreatic beta cell mass and insulin secretion in mice. The Journal of clinical investigation 2012, 122:4105-17. URL

    Boitard, C., Accili, D., Ahren, B., Cerasi, E., Seino, S., Thorens, B.: The hyperstimulated beta-cell: prelude to diabetes?. Diabetes Obes Metab 2012, 14 Suppl 3:iv-viii. URL

    Thorens, B.: Of fat, beta cells, and diabetes. Cell Metab 2011, 14:439-40. URL

    Thorens, B.: Brain glucose sensing and neural regulation of insulin and glucagon secretion. Diabetes Obes Metab 2011, 13 Suppl 1:82-8. URL

    Thorel, F., Damond, N., Chera, S., Wiederkehr, A., Thorens, B., Meda, P., Wollheim, C. B., Herrera, P. L.: Normal Glucagon Signaling and {beta}-Cell Function After Near-Total {alpha}-Cell Ablation in Adult Mice. Diabetes 2011, 60:2872-82. URL

    Poussin, C., Ibberson, M., Hall, D., Ding, J., Soto, J., Abel, E. D., Thorens, B.: Oxidative phosphorylation flexibility in the liver of mice resistant to high-fat diet-induced hepatic steatosis. Diabetes 2011, 60:2216-24. URL

    Jimenez-Preitner, M., Berney, X., Uldry, M., Vitali, A., Cinti, S., Ledford, J. G., Thorens, B.: Plac8 Is an Inducer of C/EBPbeta Required for Brown Fat Differentiation, Thermoregulation, and Control of Body Weight. Cell Metab 2011, 14:658-70. URL

    Hu He, K. H., Lorenzo, P. I., Brun, T., Jimenez Moreno, C. M., Aeberhard, D., Vallejo Ortega, J., Cornu, M., Thorel, F., Gjinovci, A., Thorens, B., Herrera, P. L., Meda, P., Wollheim, C. B., Gauthier, B. R.: In vivo conditional Pax4 overexpression in mature islet beta-cells prevents stress-induced hyperglycemia in mice. Diabetes 2011, 60:1705-15. URL

    Faivre, E., Gault, V. A., Thorens, B., Holscher, C.: Glucose-dependent insulinotropic polypeptide receptor knockout mice are impaired in learning, synaptic plasticity, and neurogenesis. J Neurophysiol 2011, 105:1574-80. URL

    Becattini, B., Marone, R., Zani, F., Arsenijevic, D., Seydoux, J., Montani, J. P., Dulloo, A. G., Thorens, B., Preitner, F., Wymann, M. P., Solinas, G.: PI3Kgamma within a nonhematopoietic cell type negatively regulates diet-induced thermogenesis and promotes obesity and insulin resistance. Proc Natl Acad Sci U S A 2011, 108:E854-63. URL

    Banasik, K., Justesen, J. M., Hornbak, M., Krarup, N. T., Gjesing, A. P., Sandholt, C. H., Jensen, T. S., Grarup, N., Andersson, A., Jorgensen, T., Witte, D. R., Sandbaek, A., Lauritzen, T., Thorens, B., Brunak, S., Sorensen, T. I., Pedersen, O., Hansen, T.: Bioinformatics-driven identification and examination of candidate genes for non-alcoholic fatty liver disease. PLoS One 2011, 6:e16542. URL

    Zhou, R., Tardivel, A., Thorens, B., Choi, I., Tschopp, J.: Thioredoxin-interacting protein links oxidative stress to inflammasome activation. Nat Immunol 2010, 11:136-40. URL

    Thorens, B., Mueckler, M.: Glucose transporters in the 21st Century. Am J Physiol Endocrinol Metab 2010, 298:E141-5. URL

    Thorens, B.: Central glucose sensing and the control of energy homeostasis. Endocrine Journal 2010, 57:S222-S222. URL

    Thorens, B.: Central control of glucose homeostasis: the brain--endocrine pancreas axis. Diabetes Metab 2010, 36 Suppl 3:S45-9. URL

    So, A., Thorens, B.: Uric acid transport and disease. J Clin Invest 2010, 120:1791-9. URL

    Mounien, L., Marty, N., Tarussio, D., Metref, S., Genoux, D., Preitner, F., Foretz, M., Thorens, B.: Glut2-dependent glucose-sensing controls thermoregulation by enhancing the leptin sensitivity of NPY and POMC neurons. Faseb J 2010, 24:1747-58. URL

    Liechti, R., Csardi, G., Bergmann, S., Schutz, F., Sengstag, T., Boj, S. F., Servitja, J. M., Ferrer, J., Van Lommel, L., Schuit, F., Klinger, S., Thorens, B., Naamane, N., Eizirik, D. L., Marselli, L., Bugliani, M., Marchetti, P., Lucas, S., Holm, C., Jongeneel, C. V., Xenarios, I.: EuroDia: a beta-cell gene expression resource. Database (Oxford) 2010, 2010:baq024. URL

    Lei, H., Poitry-Yamate, C., Preitner, F., Thorens, B., Gruetter, R.: Neurochemical profile of the mouse hypothalamus using in vivo 1H MRS at 14.1T. NMR Biomed 2010, 23:578-83. URL

    Hall, D., Poussin, C., Velagapudi, V. R., Empsen, C., Joffraud, M., Beckmann, J. S., Geerts, A. E., Ravussin, Y., Ibberson, M., Oresic, M., Thorens, B.: Peroxisomal and microsomal lipid pathways associated with resistance to hepatic steatosis and reduced pro-inflammatory state. J Biol Chem 2010, 285:31011-23. URL

    Cornu, M., Modi, H., Kawamori, D., Kulkarni, R. N., Joffraud, M., Thorens, B.: Glucagon-like peptide-1 increases beta-cell glucose competence and proliferation by translational induction of insulin-like growth factor-1 receptor expression. J Biol Chem 2010, 285:10538-45. URL

    Yang, J. Y., Walicki, J., Jaccard, E., Dubuis, G., Bulat, N., Hornung, J. P., Thorens, B., Widmann, C.: Expression of the N-terminal fragment of RasGAP in pancreatic beta cells increases their resistance to stresses and protects mice from diabetes. Diabetes 2009, 58:2596-606. URL

    Thorens, B., Mueckler, M. M.: Glucose transporters in the 21st Century. Am J Physiol Endocrinol Metab 2009,

    Silva, J. P., von Meyenn, F., Howell, J., Thorens, B., Wolfrum, C., Stoffel, M.: Regulation of adaptive behaviour during fasting by hypothalamic Foxa2. Nature 2009, 462:646-50. URL

    Preitner, F., Bonny, O., Laverriere, A., Rotman, S., Firsov, D., Da Costa, A., Metref, S., Thorens, B.: Glut9 is a major regulator of urate homeostasis and its genetic inactivation induces hyperuricosuria and urate nephropathy. Proc Natl Acad Sci U S A 2009, 8:36. URL

    Petremand, J., Bulat, N., Butty, A. C., Poussin, C., Rutti, S., Au, K., Ghosh, S., Mooser, V., Thorens, B., Yang, J. Y., Widmann, C., Waeber, G.: Involvement of 4E-BP1 in the protection induced by HDLs on pancreatic beta cells. Mol Endocrinol 2009, 23:1572-86. URL

    Isken, F., Weickert, M. O., Tschop, M. H., Nogueiras, R., Mohlig, M., Abdelrahman, A., Klaus, S., Thorens, B., Pfeiffer, A. F.: Metabolic effects of diets differing in glycaemic index depend on age and endogenous glucose-dependent insulinotrophic polypeptide in mice. Diabetologia 2009, 52:2159-68. URL

    Cornu, M., Yang, J. Y., Jaccard, E., Poussin, C., Widmann, C., Thorens, B.: Glucagon-like peptide-1 protects beta-cells against apoptosis by increasing the activity of an IGF-2/IGF-1 receptor autocrine loop. Diabetes 2009, 58:1816-25. URL

    Cornu, M., Thorens, B.: GLP-1 protects beta-cells against apoptosis by enhancing the activity of an IGF-2/IGF-1 receptor autocrine loop. Islets 2009, 1:280-282.

    Buhren, B. A., Gasis, M., Thorens, B., Muller, H. W., Bosse, F.: Glucose-dependent insulinotropic polypeptide (GIP) and its receptor (GIPR): cellular localization, lesion-affected expression, and impaired regenerative axonal growth. J Neurosci Res 2009, 87:1858-70. URL

    Bibert, S., Kharoubi Hess, S., Firsov, D., Thorens, B., Geering, K., Horisberger, J. D., Bonny, O.: Mouse GLUT9: evidences for a urate uniporter. Am J Physiol Renal Physiol 2009,

    Zehetner, J., Danzer*, C., Collins*, S., Eckhardt, K., Gerber, P. A., Ballschmieter, P., Galvanovskis, J., Shimomura, K., Ashcroft, F. M., Thorens, B., Rorsman, P., Krek, W.: pVHL is a regulator of glucose metabolism and insulin secretion in pancreatic {beta} cells. Genes Dev 2008, 22:3135-46. URL

    Troy*, S., Soty*, M., Ribeiro*, L., Laval, L., Migrenne, S., Fioramonti, X., Pillot, B., Fauveau, V., Aubert, R., Viollet, B., Foretz, M., Leclerc, J., Duchampt, A., Zitoun, C., Thorens, B., Magnan, C., Mithieux*, G., Andreelli*, F.: Intestinal gluconeogenesis is a key factor for early metabolic changes after gastric bypass but not after gastric lap-band in mice. Cell Metab 2008, 8:201-11. URL

    Thorens, B.: Glucose sensing and the pathogenesis of obesity and type 2 diabetes. Int J Obes (Lond) 2008, 32 Suppl 6:S62-71. URL

    Poussin, C., Hall, D., Minehira, K., Galzin, A. M., Tarussio, D., Thorens, B.: Different transcriptional control of metabolism and extracellular matrix in visceral and subcutaneous fat of obese and rimonabant treated mice. PLoS ONE 2008, 3:e3385. URL

    Minehira, K., Young, S. G., Villanueva, C. J., Yetukuri, L., Oresic, M., Hellerstein, M. K., Farese, R. V., Jr., Horton, J. D., Preitner, F., Thorens, Tappy, L.: Blocking VLDL secretion causes hepatic steatosis but does not affect peripheral lipid stores or insulin sensitivity in mice. J Lipid Res 2008, 49:2038-44. URL

    Klinger, S., Thorens, B.: Molecular biology of gluco-incretin function In Pancreatic Beta Cell in Health and Disease Edited by Seino, S., Bell, G.I.; Springer; 2008: 315-334.

    Klinger, S., Poussin, C., Debril, M. B., Dolci, W., Halban, P. A., Thorens, B.: Increasing GLP-1-induced beta-cell proliferation by silencing the negative regulators of signaling cAMP response element modulator-alpha and DUSP14. Diabetes 2008, 57:584-93. URL

    Isken, F., Pfeiffer, A. F., Nogueiras, R., Osterhoff, M. A., Ristow, M., Thorens, Tschop, M. H., Weickert, M. O.: Deficiency of Glucose-Dependent Insulinotropic Polypeptide (GIP) Receptor Prevents Ovariectomy-Induced Obesity in Mice. Am J Physiol Endocrinol Metab 2008, 295:E350-5. URL

    Ferdaoussi, M., Abdelli, S., Yang, J. Y., Cornu, M., Niederhauser, G., Favre, D., Widmann, C., Regazzi, R., Thorens, B., Waeber, G., Abderrahmani, A.: Exendin-4 protects {beta}-cells from interleukin 1{beta}-induced apoptosis by interfering with the c-Jun N-terminal kinases pathway. Diabetes 2008, 57:1205-15. URL

    Thorens, B.: Development and preclinical assessment of a bioartificial pancreas. Swiss Med Wkly 2007, 137 Suppl 155:68S-71S. URL

    Marty, N., Dallaporta, M., Thorens, B.: Brain glucose sensing, counterregulation, and energy homeostasis. Physiology (Bethesda) 2007, 22:241-51. URL

    Li, R., Thorens, B., Loeken, M. R.: Expression of the gene encoding the high-Km glucose transporter 2 by the early postimplantation mouse embryo is essential for neural tube defects associated with diabetic embryopathy. Diabetologia 2007, 50:682-9. URL

    Cani, P. D., Holst, J. J., Drucker, D. J., Delzenne, N. M., Thorens, B., Burcelin, R., Knauf, C.: GLUT2 and the incretin receptors are involved in glucose-induced incretin secretion. Mol Cell Endocrinol 2007, 276:18-23. URL

    Tweedie, E., Artner, I., Crawford, L., Poffenberger, G., Thorens, B., Stein, R., Powers, A. C., Gannon, M.: Maintenance of hepatic nuclear factor 6 in postnatal islets impairs terminal differentiation and function of beta-cells. Diabetes 2006, 55:3264-70. URL

    Thorens, B.: [The entero-islet axis: role of the intestine and glycemic regulation]. Journ Annu Diabetol Hotel Dieu 2006, _:67-73. URL

    Thorens, B.: A toggle for type 2 diabetes?. N Engl J Med 2006, 354:1636-8. URL

    Thorens, B.: A missing sugar prevents glucose entry: a new twist on insulin secretion. Cell Metab 2006, 3:3-5. URL

    Membrez, M., Hummler, E., Beermann, F., Haefliger, J. A., Savioz, R., Pedrazzini, T., Thorens, B.: GLUT8 is dispensable for embryonic development but influences hippocampal neurogenesis and heart function. Mol Cell Biol 2006, 26:4268-76. URL

    Mathe, Z., Dupraz, P., Rinsch, C., Thorens, B., Bosco, D., Zbinden, M., Morel, P., Berney, T., Pepper, M. S.: Tetracycline-regulated expression of VEGF-A in beta cells induces angiogenesis: improvement of engraftment following transplantation. Cell Transplant 2006, 15:621-36. URL

    Knauf, C., Rieusset, J., Foretz, M., Cani, P. D., Uldry, M., Hosokawa, M., Martinez, E., Bringart, M., Waget, A., Kersten, S., Desvergne, B., Gremlich, S., Wahli, W., Seydoux, J., Delzenne, N. M., Thorens, B., Burcelin, R.: Peroxisome proliferator-activated receptor-alpha-null mice have increased white adipose tissue glucose utilization, GLUT4, and fat mass: Role in liver and brain. Endocrinology 2006, 147:4067-78. URL

    Bady, I., Marty, N., Dallaporta, M., Emery, M., Gyger, J., Tarussio, D., Foretz, M., Thorens, B.: Evidence from glut2-null mice that glucose is a critical physiological regulator of feeding. Diabetes 2006, 55:988-95. URL

    Yang, J. Y., Walicki, J., Abderrahmani, A., Cornu, M., Waeber, G., Thorens, B., Widmann, C.: Expression of an uncleavable N-terminal RasGAP fragment in insulin-secreting cells increases their resistance toward apoptotic stimuli without affecting their glucose-induced insulin secretion. J Biol Chem 2005, 280:32835-42. URL

    Widmer, M., Uldry, M., Thorens, B.: GLUT8 subcellular localization and absence of translocation to the plasma membrane in PC12 cells and hippocampal neurons. Endocrinology 2005, 146:4727-36. URL

    Thorens, B.: [Gluco-incretin hormones in insulin secretion]. Med Sci (Paris) 2005, 21 Spec No:40-3. URL

    Marty, N., Dallaporta, M., Foretz, M., Emery, M., Tarussio, D., Bady, I., Binnert, C., Beermann, F., Thorens, B.: Regulation of glucagon secretion by glucose transporter type 2 (glut2) and astrocyte-dependent glucose sensors. J Clin Invest 2005, 115:3545-53. URL

    Foretz, M., Ancellin, N., Andreelli, F., Saintillan, Y., Grondin, P., Kahn, A., Thorens, B., Vaulont, S., Viollet, B.: Short-term overexpression of a constitutively active form of AMP-activated protein kinase in the liver leads to mild hypoglycemia and fatty liver. Diabetes 2005, 54:1331-9. URL

    Uldry, M., Thorens, B.: The SLC2 family of facilitated hexose and polyol transporters. Pflugers Arch 2004, 447:480-9. URL

    Uldry, M., Steiner, P., Zurich, M. G., Beguin, P., Hirling, H., Dolci, W., Thorens, B.: Regulated exocytosis of an H+/myo-inositol symporter at synapses and growth cones. Embo J 2004, 23:531-40. URL

    Thorens, B., Larsen, P. J.: Gut-derived signaling molecules and vagal afferents in the control of glucose and energy homeostasis. Curr Opin Clin Nutr Metab Care 2004, 7:471-8. URL

    Thorens, B.: The hepatoportal glucose sensor. Mechanisms of glucose sensing and signal transduction. In Glucokinase and Glycemic Disease: From Basics to Novel Therapeutics. Front Diabetes Volume 16. Edited by Matschinsky, FM., Magnuson, MA.; Basel: Karger; 2004: 327-38.

    Thorens, B.: Physiology of GLP-1--lessons from glucoincretin receptor knockout mice. Horm Metab Res 2004, 36:766-70. URL

    Thorens, B.: [GIP and GLP-1: multiplicity of regulator mechanisms for insulin secretion]. Journ Annu Diabetol Hotel Dieu 2004, _:111-25. URL

    Thorens, B.: Mechanisms of glucose sensing and multiplicity of glucose sensors. Ann Endocrinol (Paris) 2004, 65:9-12. URL

    Preitner, F., Ibberson, M., Franklin, I., Binnert, C., Pende, M., Gjinovci, A., Hansotia, T., Drucker, D. J., Wollheim, C., Burcelin, R., Thorens, B.: Gluco-incretins control insulin secretion at multiple levels as revealed in mice lacking GLP-1 and GIP receptors. J Clin Invest 2004, 113:635-45. URL

    Foretz, M., Thorens, B.: The facilitative glucose transporter 2: pathophysiological role in mouse and human In Membrane Transporter Diseases Edited by Broer, S., Wagner, CA.; Kluwer Academic/Plenum Publishers; 2004: 175-90.

    de Fourmestraux, V., Neubauer, H., Poussin, C., Farmer, P., Falquet, L., Burcelin, R., Delorenzi, M., Thorens, B.: Transcript profiling suggests that differential metabolic adaptation of mice to a high fat diet is associated with changes in liver to muscle lipid fluxes. J Biol Chem 2004, 279:50743-53. URL

    Cook, S., Hugli, O., Egli, M., Menard, B., Thalmann, S., Sartori, C., Perrin, C., Nicod, P., Thorens, B., Vollenweider, P., Scherrer, U., Burcelin, R.: Partial gene deletion of endothelial nitric oxide synthase predisposes to exaggerated high-fat diet-induced insulin resistance and arterial hypertension. Diabetes 2004, 53:2067-72. URL

    Burcelin, R., Uldry, M., Foretz, M., Perrin, C., Dacosta, A., Nenniger-Tosato, M., Seydoux, J., Cotecchia, S., Thorens, B.: Impaired glucose homeostasis in mice lacking the alpha1b-adrenergic receptor subtype. J Biol Chem 2004, 279:1108-15. URL

    Arluison, M., Quignon, M., Thorens, B., Leloup, C., Penicaud, L.: Immunocytochemical localization of the glucose transporter 2 (GLUT2) in the adult rat brain. II. Electron microscopic study. J Chem Neuroanat 2004, 28:137-46. URL

    Arluison, M., Quignon, M., Nguyen, P., Thorens, B., Leloup, C., Penicaud, L.: Distribution and anatomical localization of the glucose transporter 2 (GLUT2) in the adult rat brain--an immunohistochemical study. J Chem Neuroanat 2004, 28:117-36. URL

    Thorens, B.: [Gluco-incretin hormones in insulin secretion and diabetes]. Med Sci (Paris) 2003, 19:860-3. URL

    Thorens, B.: A gene knockout approach in mice to identify glucose sensors controlling glucose homeostasis. Pflugers Arch 2003, 445:482-90. URL

    Nikulina, M. A., Sandhu, N., Shamim, Z., Andersen, N. A., Oberson, A., Dupraz, P., Thorens, B., Karlsen, A. E., Bonny, C., Mandrup-Poulsen, T.: The JNK binding domain of islet-brain 1 inhibits IL-1 induced JNK activity and apoptosis but not the transcription of key proapoptotic or protective genes in insulin-secreting cell lines. Cytokine 2003, 24:13-24. URL

    Mayo, K. E., Miller, L. J., Bataille, D., Dalle, S., Goke, B., Thorens, B., Drucker, D. J.: International Union of Pharmacology. XXXV. The glucagon receptor family. Pharmacol Rev 2003, 55:167-94. URL

    Haefliger, J. A., Tawadros, T., Meylan, L., Gurun, S. L., Roehrich, M. E., Martin, D., Thorens, B., Waeber, G.: The scaffold protein IB1/JIP-1 is a critical mediator of cytokine-induced apoptosis in pancreatic beta cells. J Cell Sci 2003, 116:1463-9. URL

    Gouyon, F., Caillaud, L., Carriere, V., Klein, C., Dalet, V., Citadelle, D., Kellett, G. L., Thorens, B., Leturque, A., Brot-Laroche, E.: Simple-sugar meals target GLUT2 at enterocyte apical membranes to improve sugar absorption: a study in GLUT2-null mice. J Physiol 2003, 552:823-32. URL

    Galbiati, F., Polastri, L., Thorens, B., Dupraz, P., Fiorina, P., Cavallaro, U., Christofori, G., Davalli, A. M.: Molecular pathways involved in the antineoplastic effects of calcitriol on insulinoma cells. Endocrinology 2003, 144:1832-41. URL

    Cook, S., Hugli, O., Egli, M., Vollenweider, P., Burcelin, R., Nicod, P., Thorens, B., Scherrer, U.: Clustering of cardiovascular risk factors mimicking the human metabolic syndrome X in eNOS null mice. Swiss Med Wkly 2003, 133:360-3. URL

    Cattan, P., Rottembourg, D., Cottet, S., Tardivel, I., Dupraz, P., Thorens, B., Boitard, C., Carel, J. C.: Destruction of conditional insulinoma cell lines in NOD mice: a role for autoimmunity. Diabetologia 2003, 46:504-10. URL

    Burcelin, R., Thorens, B., Glauser, M., Gaillard, R. C., Pralong, F. P.: Gonadotropin-releasing hormone secretion from hypothalamic neurons: stimulation by insulin and potentiation by leptin. Endocrinology 2003, 144:4484-91. URL

    Burcelin, R., Crivelli, V., Perrin, C., Da Costa, A., Mu, J., Kahn, B. B., Birnbaum, M. J., Kahn, C. R., Vollenweider, P., Thorens, B.: GLUT4, AMP kinase, but not the insulin receptor, are required for hepatoportal glucose sensor-stimulated muscle glucose utilization. J Clin Invest 2003, 111:1555-62. URL

    Uldry, M., Ibberson, M., Hosokawa, M., Thorens, B.: GLUT2 is a high affinity glucosamine transporter. FEBS Lett 2002, 524:199-203. URL

    Pericin, M., Althage, A., Freigang, S., Hengartner, H., Rolland, E., Dupraz, P., Thorens, B., Aebischer, P., Zinkernagel, R. M.: Allogeneic beta-islet cells correct diabetes and resist immune rejection. Proc Natl Acad Sci U S A 2002, 99:8203-6. URL

    Joost, H. G., Bell, G. I., Best, J. D., Birnbaum, M. J., Charron, M. J., Chen, Y. T., Doege, H., James, D. E., Lodish, H. F., Moley, K. H., Moley, J. F., Mueckler, M., Rogers, S., Schurmann, A., Seino, S., Thorens, B.: Nomenclature of the GLUT/SLC2A family of sugar/polyol transport facilitators. Am J Physiol Endocrinol Metab 2002, 282:E974-6. URL

    Ibberson, M., Riederer, B. M., Uldry, M., Guhl, B., Roth, J., Thorens, B.: Immunolocalization of GLUTX1 in the testis and to specific brain areas and vasopressin-containing neurons. Endocrinology 2002, 143:276-84. URL

    Hosokawa, M., Thorens, B.: Glucose release from GLUT2-null hepatocytes: characterization of a major and a minor pathway. Am J Physiol Endocrinol Metab 2002, 282:E794-801. URL

    Cottet, S., Dupraz, P., Hamburger, F., Dolci, W., Jaquet, M., Thorens, B.: cFLIP protein prevents tumor necrosis factor-alpha-mediated induction of caspase-8-dependent apoptosis in insulin-secreting betaTc-Tet cells. Diabetes 2002, 51:1805-14. URL

    Burcelin, R., Crivelli, V., Dacosta, A., Roy-Tirelli, A., Thorens, B.: Heterogeneous metabolic adaptation of C57BL/6J mice to high-fat diet. Am J Physiol Endocrinol Metab 2002, 282:E834-42. URL

    Uldry, M., Ibberson, M., Horisberger, J. D., Chatton, J. Y., Riederer, B. M., Thorens, B.: Identification of a mammalian H(+)-myo-inositol symporter expressed predominantly in the brain. Embo J 2001, 20:4467-77. URL

    Thorens, B., Dupraz, P., Cottet, S.: Engineering tolerance into transplanted beta cell lines. Ann N Y Acad Sci 2001, 944:267-70. URL

    Thorens, B.: GLUT2 in pancreatic and extra-pancreatic gluco-detection (review). Mol Membr Biol 2001, 18:265-73. URL

    Stumpel, F., Burcelin, R., Jungermann, K., Thorens, B.: Normal kinetics of intestinal glucose absorption in the absence of GLUT2: evidence for a transport pathway requiring glucose phosphorylation and transfer into the endoplasmic reticulum. Proc Natl Acad Sci U S A 2001, 98:11330-5. URL

    Roh, C., Roduit, R., Thorens, B., Fried, S., Kandror, K. V.: Lipoprotein lipase and leptin are accumulated in different secretory compartments in rat adipocytes. J Biol Chem 2001, 276:35990-4. URL

    Joost, H. G., Thorens, B.: The extended GLUT-family of sugar/polyol transport facilitators: nomenclature, sequence characteristics, and potential function of its novel members (review). Mol Membr Biol 2001, 18:247-56. URL

    Hosokawa, M., Dolci, W., Thorens, B.: Differential sensitivity of GLUT1- and GLUT2-expressing beta cells to streptozotocin. Biochem Biophys Res Commun 2001, 289:1114-7. URL

    Holtz, J., Uldry, C., Thorens, B.: [Isocyanate-induced alveolitis in a furniture manufacture worker]. Rev Mal Respir 2001, 18:429-31. URL

    Duplain, H., Burcelin, R., Sartori, C., Cook, S., Egli, M., Lepori, M., Vollenweider, P., Pedrazzini, T., Nicod, P., Thorens, B., Scherrer, U.: Insulin resistance, hyperlipidemia, and hypertension in mice lacking endothelial nitric oxide synthase. Circulation 2001, 104:342-5. URL

    Cottet, S., Dupraz, P., Hamburger, F., Dolci, W., Jaquet, M., Thorens, B.: SOCS-1 protein prevents Janus Kinase/STAT-dependent inhibition of beta cell insulin gene transcription and secretion in response to interferon-gamma. J Biol Chem 2001, 276:25862-70. URL

    Burcelin, R., Thorens, B.: Evidence that extrapancreatic GLUT2-dependent glucose sensors control glucagon secretion. Diabetes 2001, 50:1282-9. URL

    Burcelin, R., Da Costa, A., Drucker, D., Thorens, B.: Glucose competence of the hepatoportal vein sensor requires the presence of an activated glucagon-like peptide-1 receptor. Diabetes 2001, 50:1720-8. URL

    Thorens, B., Guillam, M. T., Beermann, F., Burcelin, R., Jaquet, M.: Transgenic reexpression of GLUT1 or GLUT2 in pancreatic beta cells rescues GLUT2-null mice from early death and restores normal glucose-stimulated insulin secretion. J Biol Chem 2000, 275:23751-8. URL

    Pende, M., Kozma, S. C., Jaquet, M., Oorschot, V., Burcelin, R., Le Marchand-Brustel, Y., Klumperman, J., Thorens, B., Thomas, G.: Hypoinsulinaemia, glucose intolerance and diminished beta-cell size in S6K1-deficient mice. Nature 2000, 408:994-7. URL

    Ibberson, M., Uldry, M., Thorens, B.: GLUTX1, a novel mammalian glucose transporter expressed in the central nervous system and insulin-sensitive tissues. J Biol Chem 2000, 275:4607-12. URL

    Guillam, M. T., Dupraz, P., Thorens, B.: Glucose uptake, utilization, and signaling in GLUT2-null islets. Diabetes 2000, 49:1485-91. URL

    Dupraz, P., Cottet, S., Hamburger, F., Dolci, W., Felley-Bosco, E., Thorens, B.: Dominant negative MyD88 proteins inhibit interleukin-1beta /interferon-gamma -mediated induction of nuclear factor kappa B-dependent nitrite production and apoptosis in beta cells. J Biol Chem 2000, 275:37672-8. URL

    Burcelin, R., Dolci, W., Thorens, B.: Glucose sensing by the hepatoportal sensor is GLUT2-dependent: in vivo analysis in GLUT2-null mice. Diabetes 2000, 49:1643-8. URL

    Burcelin, R., Dolci, W., Thorens, B.: Portal glucose infusion in the mouse induces hypoglycemia: evidence that the hepatoportal glucose sensor stimulates glucose utilization. Diabetes 2000, 49:1635-42. URL

    Burcelin, R., del Carmen Munoz, M., Guillam, M. T., Thorens, B.: Liver hyperplasia and paradoxical regulation of glycogen metabolism and glucose-sensitive gene expression in GLUT2-null hepatocytes. Further evidence for the existence of a membrane-based glucose release pathway. J Biol Chem 2000, 275:10930-6. URL

    Thorens, B., Ruegger, M.: [Work capacity in the cae of pulmonary diseases]. Schweiz Med Wochenschr 1999, 129:459-64. URL

    Dupraz, P., Rinsch, C., Pralong, W. F., Rolland, E., Zufferey, R., Trono, D., Thorens, B.: Lentivirus-mediated Bcl-2 expression in betaTC-tet cells improves resistance to hypoxia and cytokine-induced apoptosis while preserving in vitro and in vivo control of insulin secretion. Gene Ther 1999, 6:1160-9. URL

    Burcelin, R., Rolland, E., Dolci, W., Germain, S., Carrel, V., Thorens, B.: Encapsulated, genetically engineered cells, secreting glucagon-like peptide-1 for the treatment of non-insulin-dependent diabetes mellitus. Ann N Y Acad Sci 1999, 875:277-85. URL

    Burcelin, R., Dolci, W., Thorens, B.: Long-lasting antidiabetic effect of a dipeptidyl peptidase IV-resistant analog of glucagon-like peptide-1. Metabolism 1999, 48:252-8. URL

    Serre, V., Dolci, W., Schaerer, E., Scrocchi, L., Drucker, D., Efrat, S., Thorens, B.: Exendin-(9-39) is an inverse agonist of the murine glucagon-like peptide-1 receptor: implications for basal intracellular cyclic adenosine 3',5'-monophosphate levels and beta-cell glucose competence. Endocrinology 1998, 139:4448-54. URL

    Pralong, F. P., Roduit, R., Waeber, G., Castillo, E., Mosimann, F., Thorens, B., Gaillard, R. C.: Leptin inhibits directly glucocorticoid secretion by normal human and rat adrenal gland. Endocrinology 1998, 139:4264-8. URL

    Guillam, M. T., Burcelin, R., Thorens, B.: Normal hepatic glucose production in the absence of GLUT2 reveals an alternative pathway for glucose release from hepatocytes. Proc Natl Acad Sci U S A 1998, 95:12317-21. URL

    Almind, K., Ambye, L., Urhammer, S. A., Hansen, T., Echwald, S. M., Holst, J. J., Gromada, J., Thorens, B., Pedersen, O.: Discovery of amino acid variants in the human glucose-dependent insulinotropic polypeptide (GIP) receptor: the impact on the pancreatic beta cell responses and functional expression studies in Chinese hamster fibroblast cells. Diabetologia 1998, 41:1194-8. URL

    Widmann, C., Dolci, W., Thorens, B.: Internalization and homologous desensitization of the GLP-1 receptor depend on phosphorylation of the receptor carboxyl tail at the same three sites. Mol Endocrinol 1997, 11:1094-102. URL

    Weber-Chappuis, K., Thorens, B.: [Histiocytosis X falsely diagnosed as silicosis]. Rev Med Suisse Romande 1997, 117:901-5. URL

    Waeber, G., Calandra, T., Roduit, R., Haefliger, J. A., Bonny, C., Thompson, N., Thorens, B., Temler, E., Meinhardt, A., Bacher, M., Metz, C. N., Nicod, P., Bucala, R.: Insulin secretion is regulated by the glucose-dependent production of islet beta cell macrophage migration inhibitory factor. Proc Natl Acad Sci U S A 1997, 94:4782-7. URL

    Roduit, R., Thorens, B.: Inhibition of glucose-induced insulin secretion by long-term preexposure of pancreatic islets to leptin. FEBS Lett 1997, 415:179-82. URL

    Guillam, M. T., Hummler, E., Schaerer, E., Yeh, J. I., Birnbaum, M. J., Beermann, F., Schmidt, A., Deriaz, N., Thorens, B.: Early diabetes and abnormal postnatal pancreatic islet development in mice lacking Glut-2. Nat Genet 1997, 17:327-30. URL

    Gremlich, S., Roduit, R., Thorens, B.: Dexamethasone induces posttranslational degradation of GLUT2 and inhibition of insulin secretion in isolated pancreatic beta cells. Comparison with the effects of fatty acids. J Biol Chem 1997, 272:3216-22. URL

    Gremlich, S., Bonny, C., Waeber, G., Thorens, B.: Fatty acids decrease IDX-1 expression in rat pancreatic islets and reduce GLUT2, glucokinase, insulin, and somatostatin levels. J Biol Chem 1997, 272:30261-9. URL

    Bonny, C., Roduit, R., Gremlich, S., Nicod, P., Thorens, B., Waeber, G.: The loss of GLUT2 expression in the pancreatic beta-cells of diabetic db/db mice is associated with an impaired DNA-binding activity of islet-specific trans-acting factors. Mol Cell Endocrinol 1997, 135:59-65. URL

    Widmann, C., Dolci, W., Thorens, B.: Heterologous desensitization of the glucagon-like peptide-1 receptor by phorbol esters requires phosphorylation of the cytoplasmic tail at four different sites. J Biol Chem 1996, 271:19957-63. URL

    Widmann, C., Dolci, W., Thorens, B.: Desensitization and phosphorylation of the glucagon-like peptide-1 (GLP-1) receptor by GLP-1 and 4-phorbol 12-myristate 13-acetate. Mol Endocrinol 1996, 10:62-75. URL

    Thorens, B., Widmann, C.: Signal transduction and desensitization of the glucagon-like peptide-1 receptor. Acta Physiol Scand 1996, 157:317-9. URL

    Thorens, B., Roth, J.: Intracellular targeting of GLUT4 in transfected insulinoma cells: evidence for association with constitutively recycling vesicles distinct from synaptophysin and insulin vesicles. J Cell Sci 1996, 109 ( Pt 6):1311-23. URL

    Thorens, B., Gremlich, S., Roduit, R., Widmann, C.: [1996 Apollinaire Bouchardat Prize. Molecular aspects of control of insulin secretion]. Journ Annu Diabetol Hotel Dieu 1996,
    55-68. URL

    Thorens, B., Deriaz, N., Bosco, D., DeVos, A., Pipeleers, D., Schuit, F., Meda, P., Porret, A.: Protein kinase A-dependent phosphorylation of GLUT2 in pancreatic beta cells. J Biol Chem 1996, 271:8075-81. URL

    Thorens, B.: Glucose transporters in the regulation of intestinal, renal, and liver glucose fluxes. Am J Physiol 1996, 270:G541-53. URL

    Moens, K., Heimberg, H., Flamez, D., Huypens, P., Quartier, E., Ling, Z., Pipeleers, D., Gremlich, S., Thorens, B., Schuit, F.: Expression and functional activity of glucagon, glucagon-like peptide I, and glucose-dependent insulinotropic peptide receptors in rat pancreatic islet cells. Diabetes 1996, 45:257-61. URL

    Alvarez, E., Roncero, I., Chowen, J. A., Thorens, B., Blazquez, E.: Expression of the glucagon-like peptide-1 receptor gene in rat brain. J Neurochem 1996, 66:920-7. URL

    Widmann, C., Dolci, W., Thorens, B.: Agonist-induced internalization and recycling of the glucagon-like peptide-1 receptor in transfected fibroblasts and in insulinomas. Biochem J 1995, 310 ( Pt 1):203-14. URL

    Thorens, B.: Glucagon-like peptide-1 and control of insulin secretion. Diabete Metab 1995, 21:311-8. URL

    Regazzi, R., Wollheim, C. B., Lang, J., Theler, J. M., Rossetto, O., Montecucco, C., Sadoul, K., Weller, U., Palmer, M., Thorens, B.: VAMP-2 and cellubrevin are expressed in pancreatic beta-cells and are essential for Ca(2+)-but not for GTP gamma S-induced insulin secretion. Embo J 1995, 14:2723-30. URL

    Ogawa, Y., Noma, Y., Davalli, A. M., Wu, Y. J., Thorens, B., Bonner-Weir, S., Weir, G. C.: Loss of glucose-induced insulin secretion and GLUT2 expression in transplanted beta-cells. Diabetes 1995, 44:75-9. URL

    Heimberg, H., De Vos, A., Pipeleers, D., Thorens, B., Schuit, F.: Differences in glucose transporter gene expression between rat pancreatic alpha- and beta-cells are correlated to differences in glucose transport but not in glucose utilization. J Biol Chem 1995, 270:8971-5. URL

    Gros, L., Hollande, F., Thorens, B., Kervran, A., Bataille, D.: Comparative effects of GLP-1-(7-36) amide, oxyntomodulin and glucagon on rabbit gastric parietal cell function. Eur J Pharmacol 1995, 288:319-27. URL

    Gremlich, S., Porret, A., Hani, E. H., Cherif, D., Vionnet, N., Froguel, P., Thorens, B.: Cloning, functional expression, and chromosomal localization of the human pancreatic islet glucose-dependent insulinotropic polypeptide receptor. Diabetes 1995, 44:1202-8. URL

    Bosco, D., Meda, P., Thorens, B., Malaisse, W. J.: Heterogeneous secretion of individual B cells in response to D-glucose and to nonglucidic nutrient secretagogues. Am J Physiol 1995, 268:C611-8. URL

    Widmann, C., Burki, E., Dolci, W., Thorens, B.: Signal transduction by the cloned glucagon-like peptide-1 receptor: comparison with signaling by the endogenous receptors of beta cell lines. Mol Pharmacol 1994, 45:1029-35. URL

    Thorens, B., Roduit, R.: Regulated expression of GLUT2 in diabetes studied in transplanted pancreatic beta cells. Biochem Soc Trans 1994, 22:684-7. URL

    Thorens, B.: [GLP-1 and the control of insulin secretion]. Journ Annu Diabetol Hotel Dieu 1994,
    33-46. URL

    Canessa, C. M., Schild, L., Buell, G., Thorens, B., Gautschi, I., Horisberger, J. D., Rossier, B. C.: Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits. Nature 1994, 367:463-7. URL

    Thorens, B., Waeber, G.: Glucagon-like peptide-I and the control of insulin secretion in the normal state and in NIDDM. Diabetes 1993, 42:1219-25. URL

    Thorens, B., Porret, A., Buhler, L., Deng, S. P., Morel, P., Widmann, C.: Cloning and functional expression of the human islet GLP-1 receptor. Demonstration that exendin-4 is an agonist and exendin-(9-39) an antagonist of the receptor. Diabetes 1993, 42:1678-82. URL

    Thorens, B., Gerard, N., Deriaz, N.: GLUT2 surface expression and intracellular transport via the constitutive pathway in pancreatic beta cells and insulinoma: evidence for a block in trans-Golgi network exit by brefeldin A. J Cell Biol 1993, 123:1687-94. URL

    Thorens, B.: Facilitated glucose transporters in epithelial cells. Annu Rev Physiol 1993, 55:591-608. URL

    Gros, L., Thorens, B., Bataille, D., Kervran, A.: Glucagon-like peptide-1-(7-36) amide, oxyntomodulin, and glucagon interact with a common receptor in a somatostatin-secreting cell line. Endocrinology 1993, 133:631-8. URL

    Grobholz, R., Hacker, H. J., Thorens, B., Bannasch, P.: Reduction in the expression of glucose transporter protein GLUT 2 in preneoplastic and neoplastic hepatic lesions and reexpression of GLUT 1 in late stages of hepatocarcinogenesis. Cancer Res 1993, 53:4204-11. URL

    Thorens, B., Wu, Y. J., Leahy, J. L., Weir, G. C.: The loss of GLUT2 expression by glucose-unresponsive beta cells of db/db mice is reversible and is induced by the diabetic environment. J Clin Invest 1992, 90:77-85. URL

    Thorens, B.: Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1. Proc Natl Acad Sci U S A 1992, 89:8641-5. URL

    Thorens, B.: Molecular and cellular physiology of GLUT-2, a high-Km facilitated diffusion glucose transporter. Int Rev Cytol 1992, 137:209-38. URL

    Tal, M., Thorens, B., Surana, M., Fleischer, N., Lodish, H. F., Hanahan, D., Efrat, S.: Glucose transporter isotypes switch in T-antigen-transformed pancreatic beta cells growing in culture and in mice. Mol Cell Biol 1992, 12:422-32. URL

    Chen, C., Thorens, B., Bonner-Weir, S., Weir, G. C., Leahy, J. L.: Recovery of glucose-induced insulin secretion in a rat model of NIDDM is not accompanied by return of the B-cell GLUT2 glucose transporter. Diabetes 1992, 41:1320-7. URL

    Boillat, M. A., Thorens, B.: [Acro-syndromes and occupational diseases: epidemiology and prevention of disease due to vibrating equipment]. Rev Med Suisse Romande 1992, 112:405-7. URL

    Aghayan, M., Rao, L. V., Smith, R. M., Jarett, L., Charron, M. J., Thorens, B., Heyner, S.: Developmental expression and cellular localization of glucose transporter molecules during mouse preimplantation development. Development 1992, 115:305-12. URL

    Zhang, R., Alper, S. L., Thorens, B., Verkman, A. S.: Evidence from oocyte expression that the erythrocyte water channel is distinct from band 3 and the glucose transporter. J Clin Invest 1991, 88:1553-8. URL

    Thorens, B.: [Accident insurance, CNA and medical corps]. Rev Med Suisse Romande 1991, 111:933-6. URL

    Hogan, A., Heyner, S., Charron, M. J., Copeland, N. G., Gilbert, D. J., Jenkins, N. A., Thorens, B., Schultz, G. A.: Glucose transporter gene expression in early mouse embryos. Development 1991, 113:363-72. URL

    Hacker, H. J., Thorens, B., Grobholz, R.: Expression of facilitative glucose transporter in rat liver and choroid plexus. A histochemical study in native cryostat sections. Histochemistry 1991, 96:435-9. URL

    Thorens, B., Weir, G. C., Leahy, J. L., Lodish, H. F., Bonner-Weir, S.: Reduced expression of the liver/beta-cell glucose transporter isoform in glucose-insensitive pancreatic beta cells of diabetic rats. Proc Natl Acad Sci U S A 1990, 87:6492-6. URL

    Thorens, B., Lodish, H. F., Brown, D.: Differential localization of two glucose transporter isoforms in rat kidney. Am J Physiol 1990, 259:C286-94. URL

    Thorens, B., Flier, J. S., Lodish, H. F., Kahn, B. B.: Differential regulation of two glucose transporters in rat liver by fasting and refeeding and by diabetes and insulin treatment. Diabetes 1990, 39:712-9. URL

    Thorens, B., Cheng, Z. Q., Brown, D., Lodish, H. F.: Liver glucose transporter: a basolateral protein in hepatocytes and intestine and kidney cells. Am J Physiol 1990, 259:C279-85. URL

    Thorens, B., Charron, M. J., Lodish, H. F.: Molecular physiology of glucose transporters. Diabetes Care 1990, 13:209-18. URL

    Tal, M., Schneider, D. L., Thorens, B., Lodish, H. F.: Restricted expression of the erythroid/brain glucose transporter isoform to perivenous hepatocytes in rats. Modulation by glucose. J Clin Invest 1990, 86:986-92. URL

    Orci, L., Unger, R. H., Ravazzola, M., Ogawa, A., Komiya, I., Baetens, D., Lodish, H. F., Thorens, B.: Reduced beta-cell glucose transporter in new onset diabetic BB rats. J Clin Invest 1990, 86:1615-22. URL

    Johnson, J. H., Newgard, C. B., Milburn, J. L., Lodish, H. F., Thorens, B.: The high Km glucose transporter of islets of Langerhans is functionally similar to the low affinity transporter of liver and has an identical primary sequence. J Biol Chem 1990, 265:6548-51. URL

    Suzue, K., Lodish, H. F., Thorens, B.: Sequence of the mouse liver glucose transporter. Nucleic Acids Res 1989, 17:10099. URL

    Orci, L., Thorens, B., Ravazzola, M., Lodish, H. F.: Localization of the pancreatic beta cell glucose transporter to specific plasma membrane domains. Science 1989, 245:295-7. URL

    Collart, M. A., Belin, D., Briottet, C., Thorens, B., Vassalli, J. D., Vassalli, P.: Receptor-mediated phagocytosis by macrophages induces a calcium-dependent transient increase in c-fos transcription. Oncogene 1989, 4:237-41. URL

    Thorens, B., Sarkar, H. K., Kaback, H. R., Lodish, H. F.: Cloning and functional expression in bacteria of a novel glucose transporter present in liver, intestine, kidney, and beta-pancreatic islet cells. Cell 1988, 55:281-90. URL

    Sarkar, H. K., Thorens, B., Lodish, H. F., Kaback, H. R.: Expression of the human erythrocyte glucose transporter in Escherichia coli. Proc Natl Acad Sci U S A 1988, 85:5463-7. URL

    Eliason, J. F., Thorens, B., Kindler, V., Vassalli, P.: The roles of granulocyte-macrophage colony-stimulating factor and interleukin 3 in stromal cell-mediated hemopoiesis in vivo. Exp Hematol 1988, 16:307-12. URL

    Thorens, B., Mermod, J. J., Vassalli, P.: Phagocytosis and inflammatory stimuli induce GM-CSF mRNA in macrophages through posttranscriptional regulation. Cell 1987, 48:671-9. URL

    Kindler, V., Thorens, B., Vassalli, P.: In vivo effect of murine recombinant interleukin 3 on early hemopoietic progenitors. Eur J Immunol 1987, 17:1511-4. URL

    Thorens, B., Vassalli, P.: Chloroquine and ammonium chloride prevent terminal glycosylation of immunoglobulins in plasma cells without affecting secretion. Nature 1986, 321:618-20. URL

    Kindler, V., Thorens, B., de Kossodo, S., Allet, B., Eliason, J. F., Thatcher, D., Farber, N., Vassalli, P.: Stimulation of hematopoiesis in vivo by recombinant bacterial murine interleukin 3. Proc Natl Acad Sci U S A 1986, 83:1001-5. URL

    Thorens, B., Schulz, M. F., Vassalli, P.: Bone marrow pre-B lymphocytes synthesize immunoglobulin mu chains of membrane type with different properties and intracellular pathways. Embo J 1985, 4:361-8. URL

    Thorens, B., Roth, J., Norman, A. W., Perrelet, A., Orci, L.: Immunocytochemical localization of the vitamin D-dependent calcium binding protein in chick duodenum. J Cell Biol 1982, 94:115-22. URL

    Roth, J., Thorens, B., Hunziker, W., Norman, A. W., Orci, L.: Vitamin D--dependent calcium binding protein: immunocytochemical localization in chick kidney. Science 1981, 214:197-200. URL

    Koller, F., Thorens, B., Riondel, A. M., Scholer, D.: [Proceedings: Cushing's syndrome in hypernephroid carcinoma; normalization of the cortisol value, hypokalemia and hypertension under metopirone]. Helv Med Acta 1974, 37:393-4. URL

    Meyer, J. J., Rey, P., Thorens, B., Beaumanoir, A.: [Examination of subjects with craniocerebral trauma using a visual perception test: the de Lange curve]. Schweiz Arch Neurol Neurochir Psychiatr 1971, 108:213-21. URL
 inside this site:
Génopode - CH-1015 Lausanne  - Switzerland  -  Tel. +41 21 69239 00  -  Fax +41 21 69239 05
Swiss University