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Mehdi Tafti, Co-director of the Center For Investigation And Research In Sleep (with Raphaël Heinzer - CHUV)

Mehdi Tafti received his PhD from the University of Montpellier (France) in 1991 after completing his doctoral thesis on sleep regulation in human narcolepsy. He performed a postdoctoral fellowship with Dr. Mignot and Dr. Dement and was a Research Associate at the Department of Psychiatry and Biological Sciences at Stanford University. In 1995 he moved to the Department of Psychiatry in Geneva where he established the first laboratory dedicated to the molecular genetics of sleep and sleep disorders. He joined the Center for Integrative Genomics in September 2004.

Sleep, circadian rhythms, mouse genomics, QTL, sleep disorders


The CIRS in brief
Sleep disorders are very prevalent, and represent an « emerging worldwide epidemic ». However, despite an impressive progress during the last 3 decades, biological and molecular bases of most sleep disorders remain unknown. Consequently, almost all available treatments for sleep disorders are symptomatic and not evidence-based. Given their variety and impact on different biological systems (respiration, metabolism, motor control, cognition), a multidisciplinary approach is needed, not only for understanding the pathophysiology but also for diagnosis and treatment of sleep disorders. Thus, in collaboration with clinicians specialist in sleep disorders, we have established the Center for Investigation and Research in Sleep (CIRS). This joint venture between the CIG and the centre Hospitalier Universitaire (CHUV) will provide a state-of-the-art infrastructure to conduct high level basic and clinical research and to offer to the community the highest standard for diagnosis and treatment of sleep disorders. CIRS has been officially inaugurated in January 2007.
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