Publications

2012

Meunier, J., Lemoine, F., Soumillon, M., Liechti, A., Weier, M., Guschanski, K., Hu, H., Khaitovich, P., and Kaessmann, H. (2012) Birth and expression evolution of mammalian microRNA genes. Genome Res. (Epub Oct 3).

Julien, P., Brawand, D., Soumillon, M., Necsulea, A., Liechti, A., Schütz, F., Daish, T., Grützner, F., and Kaessmann, H. (2012) Mechanisms and evolutionary patterns of mammalian and avian dosage compensation. PLoS Biol. 5:e1001328.

 

2011

Brawand, D., Soumillon, M., Necsulea, A., Julien, P., Csárdi, G., Harrigan, P., Weier, M., Liechti, A., Aximu-Petri, A., Kircher, M., Albert, F.W., Zeller, U., Khaitovich, P., Grützner, F., Bergmann, S., Nielsen, R., Pääbo, S., and Kaessmann, H. (2011) The evolution of gene expression levels in mammalian organs. Nature 478: 343-348. URL

Romero, Y., Meikar, O., Papaioannou, M.D., Conne, B., Grey, C., Weier, M., Pralong, F., De Massy, B., Kaessmann, H., Vassalli, J.D., Kotaja, N., Nef, S. (2011) Dicer1 depletion in male germ cells leads to infertility due to cumulative meiotic and spermiogenic defects. PLoS One 6: e25241. URL

 

2010

Croset, V., Rytz, R., Cummins, S.F., Budd, A., Brawand, D., Kaessmann, H., Gibson, T.J., and Benton, R. (2010) Ancient Protostome Origin of Chemosensory Ionotropic Glutamate Receptors and the Evolution of Insect Taste and Olfaction. PLoS Genet. 6: e1001064. URL

Kaessmann, H. (2010) Origins, evolution and phenotypic impact of new genes. Genome Res. 20: 1313-1326. URL

Pradervand, S., Weber, J., Lemoine, F., Consales, F., Paillusson, A., Dupasquier, M., Thomas, J., Richter, H., Kaessmann, H., Beaudoing, E., Hagenbüchle, O., and Harshman, K. (2010) Concordance among digital gene expression, microarrays, and qPCR when measuring differential expression of microRNAs. Biotechniques 48: 219-222. URL

Potrzebowski, L., Vinckenbosch, N., and Kaessmann, H. (2010) The emergence of new genes on the young therian X. Trends Genet. 26: 1-4. URL

 

2009 

Fablet, M., Bueno, M., Potrzebowski, L., and Kaessmann, H. (2009) Evolutionary origin and functions of retrogene introns. Mol. Biol. Evol. 26: 2147-2156. URL

Kaessmann, H. (2009) More than just a copy. Science 325: 958-959. URL

Henrichsen, C. N., Vinckenbosch, N., Zollner, S., Chaignat, E., Pradervand, S., Schutz, F., Ruedi, M., *Kaessmann, H., and *Reymond, A. (2009) Segmental copy number variation shapes tissue transcriptomes. Nat. Genet. 41: 424-429 URL

Kaessmann, H., Vinckenbosch, N., and Long, M.: RNA-based gene duplication: mechanistic and evolutionary insights. (2009) Nat. Rev. Genet. 10: 19-31. URL

 

2008  

Brawand, D., Wahli, W. and Kaessmann, H. (2008) Loss of egg yolk genes in mammals and the origin of lactation and placentation. PLoS Biol. 3: e63. URL

Goldschmidt, V., Ciuffi, A., Ortiz, M., Brawand, D., Munoz, M., *Kaessmann, H. and *Telenti, A. (2008) Anti–Retroviral Activity of Ancestral TRIM5α. J. Virol. 82: 2089–2096. URL

Marques, A., Vinckenbosch, N., Brawand, D., and Kaessmann, H. (2008) Functional diversification of duplicate genes through subcellular adaptation of encoded proteins. Genome Biol. 9: R54. URL

Ortiz, M., Kaessmann, H., Zhang, K., Bashirova, A., Carrington, M., Quintana–Murci, L., and Telenti, A. (2008) The evolutionary history of the CD209 (DC–SIGN) family in humans and non–human primates. Genes Immun. 9: 483–492. URL

Potrzebowski, L., Vinckenbosch, N., Marques, A., Chalmel, F., Jégou, B., and Kaessmann, H. (2008) Chromosomal gene movements reflect the recent origin and biology of therian sex chromosomes. PLoS Biol. 4: e80. URL

Rosso, L., Keller, L., Kaessmann, H., and Hammond, R. (2008) Mating system and avpr1a promoter variation in primates. Biology letters 4: 375–378. URL

Rosso, L., Marques, A., Reichert, A., and Kaessmann, H. (2008) Mitochondrial targeting adaptation of the hominoid–specific glutamate dehydrogenase driven by positive Darwinian selection PLoS Genet. 4: e1000150. URL

Rosso, L., Marques, A., Weier, M., Lambert, N., Lambot, M.A., Vanderhaeghen, P., and Kaessmann, H. (2008) Birth and rapid subcellular adaptation of a hominoid–specific CDC14 protein. PLoS Biol. 6: e140. URL

 

2007

Parmley, J.L., Potrzebowski, L., Kaessmann, H., and Hurst, L. (2007) Splicing and the evolution of proteins in mammals. PLoS Biol. 5: e26. URL

 

 

 

2006

 

Dupanloup, I. and Kaessmann, H. (2006) Evolutionary simulations to detect functional lineage–specific genes. Bioinformatics 22: 1815–1822. URL

Ortiz M, Bleiber G, Martinez R, *Kaessmann H. and *Telenti A. (2006) Patterns of evolution of host proteins involved in retroviral pathogenesis. Retrovirol. 3: 11. URL

Vinckenbosch, N., Dupanloup, I. and Kaessmann, H. (2006) Evolutionary fate of retroposed gene copies in the human genome. Proc. Natl. Acad. Sci. USA 103: 3220–3225. URL

2005

 

Marques, A., Dupanloup, I., Vinckenbosch, N., Reymond, A., and Kaessmann, H. (2005) Emergence of young human genes after a burst of retroposition in primates. PLoS Biol. 3: e357. URL

2004 

Betran, E., Kaessmann, H., Emerson, J.J., and Long, M. (2004) Sex chromosomes and male functions – where do new genes go? Cell Cycle 7: 873-875. URL

Burki, F. and Kaessmann, H. (2004) Birth and adaptive evolution of a hominoid gene supporting high neurotransmitter flux. Nat. Genet. 10: 1061–1063. URL

*Emerson, J.J., *Kaessmann, H., Betran, E., and Long, M. (2004) Extensive gene traffic on the mammalian X chromosome. Science 303: 537–540. URL

International Chicken Genome Sequencing Consortium (Kaessmann H. – member). (2004) Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution. Nature 432: 695–716. URL

 

2003

Kaessmann, H. (2003) Human and chimpanzee nucleotide diversity. In: Encyclopedia of the human genome. Edited by Cooper, David N.; Nature Publishing Group.

 

2002 

Kaessmann, H., Paabo, S.: The genetical history of humans and the great apes. J Intern Med 2002, 251:1-18. URL

Kaessmann, H., Zollner, S., Nekrutenko, A., and Li, W. H. (2002) Signatures of domain shuffling in the human genome. Genome Res. 12: 1642-50. URL

Kaessmann, H., Zöllner, S., Gustafsson, A. C., Wiebe, V., Laan, M., Lundeberg, J., Uhlen, M., and Paabo, S. (2002) Extensive linkage disequilibrium in small human populations in Eurasia. Am J Hum Genet. 70: 673-85. URL

Schrenk, F., Brommage, G., Kaessmann, H. (2002) Die Frühzeit des Menschen: Zurück zu den Wurzeln. Biologie in unserer Zeit 32: 352-359. URL

 

2001 

Kaessmann, H., Wiebe, V., Weiss, G., Paabo, S. (2001) Great ape DNA sequences reveal a reduced diversity and an expansion in humans. Nature Genet. 27:155-6. URL

 

2000

 

Ingman, M., Kaessmann, H., Paabo, S., and Gyllensten, U. (2000) Mitochondrial genome variation and the origin of modern humans. Nature 408: 708-13. URL

1999

 

Kaessmann, H., Heissig, F., von Haeseler, A., and Paabo, S. (1999) DNA sequence variation in a non-coding region of low recombination on the human X chromosome. Nat. Genet. 22: 78-81. URL

Kaessmann, H., Wiebe, V., and Paabo, S. (1999) Extensive nuclear DNA sequence diversity among chimpanzees. Science 286: 1159-62. URL