Christophe's Group

Website Dessimoz lab

2017 Highlights

It was a big year for the OMA (Orthologous Matrix) project. We introduced changes to the algorithm to make it more robust to duplicated genes evolving at different rates, and to make it more scalable (http://doi.org/10.1093/bioinformatics/btx229). We also released numerous improvements for our end users in form of better web and programmatic interfaces (http://doi.org/10.1093/nar/gkx1019). 

 

Among several collaborative works published this year, we systematically surveyed structural variations within the known world population of fission yeast (Jeffares et al, Nat Comm, http://doi.org/10.1038/ncomms14061). We observed a surprisingly rapid turnover of duplications within the population, and strong association with several quantitative traits and reproductive isolation. Blog post: http://lab.dessimoz.org/blog/2017/02/08/sex-alcohol-and-structural-variants-in-fission-yeast.

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