Kana Yamada


My research is to understand molecular evolution of Rubisco sub-units in Angiosperms.
RUBISCO is the most abundant protein and the key enzyme of photosynthesis. The different types of photosynthesis present in flowering plants have different efficiencies to concentrate and metabolite atmospheric CO2. In particular, two types, called C3 and C4, have evolved multiple times in specific plant families like the grasses. The key enzyme in photosynthesis is RUBISCO, which is constituted of 8 small and 8 large subunits, encoded by the rbcS and rbcL genes, respectively. Both genes are involved in the CO2 fixation pathway but the specific role of each gene is not known very well.
In this study, I investigate the evolution of the rbcS and rbcL genes for all flowering plant species. I estimate the occurrence of episodic events of positive selection along the branches of the phylogenetic trees of both genes to better understand the functional constraint during their evolution. I further estimate the coevolution between the two subunits to better understand the possible functional and structural interactions existing between them. The large-scale evolutionary analyses are complemented by a more detailed investigation of the evolution of this rbcL/rbcS complex in C3 and C4 transitions in grasses.

Ph.D., Computational phylogenetics lab, Department of Ecology and Evolution, University of Lausanne (Lausanne, Switzerland)

Project Researcher, Pharmacotherapeutics lab, Faculty of Pharmacy, Keio University (Tokyo, Japan)

Boursiere du Gouvernement Français, Physiologie de la Nutrition et du Comportement Alimentaire, INRA/AgroParisTech (Paris, France)

Master of Applied Biological Chemistry, lab of “Food for life” sponsored by Nestlé (lab of Nutritional Chemistry until 2009), University of Tokyo (Tokyo, Japan)

Bachelor of Agrobiology, lab of Animal breeding, University of Niigata (Niigata, Japan)

Others activities

Founding original member of Non-profit organization, Yam Yum soul soup kitchen, to support connecting local farmers and consumers in Japan and Thailand

Volunteer for supporting children from Fukushima (Paris, France)

Obtained License of artificial insemination for cows (valid only in Japan)

Internship at Suzue Patent Office (Tokyo, Japan)

Volunteer for supporting victims of floods (Niigata, Japan)



Member of Salamin group

Biophore - CH-1015 Lausanne
Tel. +41 21 692 41 60
Fax +41 21 692 41 65