Go to: content | top | bottom | search
 
 
You are hereUNIL > Department of Ecology and Evolution > Research & Education > Research > Research groups > Waterhouse Group

Waterhouse Group - Evolutionary Genomics

Elucidating gene evolution - gene function interactions through arthropod evolutionary and functional genomics

Evolutionary Genomics

While computational methods for predicting gene functions are improving, they often fail to provide biologists with the evidence required to design and perform comprehensive experiments that probe these putative roles in detail. Addressing these challenges, the group’s principal research aim is to develop quantitative measures of gene evolutionary traits and classify genes into multiple functionally-related categories in order to build reliable predictive models of the relationships between the underlying genetics and the observable biological traits. The goal of this framework is to identify genes with similar evolutionary profiles in order to expand hypotheses on genomic functions by predicting new members of biological pathways or processes based on shared evolutionary traits.

Arthropod Genomics

The focus of the group’s research is on computational comparative evolutionary and functional genomics of disease-vector mosquitoes and other insects: exploring the links between gene evolution and gene function through an evolutionary systems biology framework. In this regard insects and other arthropods have a lot to offer: with their countless adaptations to exploit many ecological niches they are ideal for investigating how conservation or divergence and gains or losses of functional genomic elements give rise to the splendour of animal biology. As falling sequencing costs improve genomic species sampling and enrich sources of functional data, the quantities and types of ‘observable features’ are growing rapidly. The challenge therefore is how do we best exploit these data to reach new levels of depth and detail in our understanding of biology?

Characterisation, Control, & Conservation

The incredible diversity of insects makes them fascinating to study, as models for processes like ageing and sociality, and because of their roles in human, livestock, and crop health as disease vectors, in agriculture as pests, pollinators, or bio-control agents, and more generally in ecology and environmental conservation. In striving towards our goals of building an evolutionary systems biology framework that accelerates the discovery of novel insect biology, the results of our research will provide biologists with the tools they need to apply this knowledge to the characterisation of animal biology, the control of disease vectors and pests, and the conservation of threatened insects and their ecosystems.

Find out more about the lab: http://rmwaterhouse.org/lab

Advanced search is available through Serval

Publications can be managed by accessing Serval via  MyUnil

Publications

 
2017 | 2016 | 2015 | 2014 | 2013 | 2011 | 2010 | 2009 | 2008 | 2007 |
2017
2016
2015
2014
2013
2011
2010
2009
2008
2007
 
 
 
 
 
 
 
 

Graduate Students

Masters Students

  • Eleonore Lavanchy
  • Massimo Bourquin
  • Tess Bonato

Informal applications to join the group are welcome at any time. Please send an email to Prof. Waterhouse with:

  • Cover Letter – your motivation to join the group
  • Curriculum Vitae – your experience to date, including publications
Search:
 Go
 
rss/atom

RWaterhouse2.jpg

Felix Imhof © UNIL

Robert Waterhouse
Office room: 3211
Phone: +41(0)21 692 4105
Fax: +41(0)21 692 4165
robert.waterhouse[@]unil.ch

Administrative assistant
Office room: 3106
Phone: +4121 692 4200
Fax: +4121 692 4265
anne.cuendet[@]unil.ch

Biophore - CH-1015 Lausanne  - Switzerland  -  Tel. +41 21 692 41 60  -  Fax +41 21 692 41 65
Swiss University