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Goudet Group - Population Genetics & Genomics.

The main focus of the group concerns the understanding of the interplay of population structure, trait architecture, and  selection. For this, we use different approaches, from theory and the development of statistical tools to field observations. The main biological models currently used are the barn owl (in collaboration with Alexandre Roulin), and Miniopterus bats (with  Philippe Christe). On the theoretical side, we investigate the dynamics of multilocus genetic system under the influence of selection, migration and drift, developed conprehensive individual based models and develop statistical methods to infer selection, mating systems and population structure.



Collaborator(s): Samuel Neuenschwander

We developed, and are still actively developing, the computer program quantiNEMO, an individual-based, genetically explicit stochastic simulation program. It allows investigating the effects of slection, mutation, recombination and drift on quantitative traits with varying architectures in spatially structured populations connected by migration and located in a heterogeneous habitat. See quantiNEMO website

Statitical methods & Software developments

Collaborators: Samuel Neuenschwander , Frédéric Hospital (INRA), Nicolas Perrin, Peter Waser (Purdue, USA), Guillaume Evanno (INRA), Helene Collin

Molecular markers are plentifull nowadays, and of different types. The type of information that these markers can provide for understanding different aspects of the ecology of species is enormous, but largely unexplored. For instance, we showed that sex-biased dispersal can be detected using genetic markers. Statistical tools for analysing genetic data are often complex, and require specific packages. To this end, I developed the package hierfstat for R, and the following programs: FSTAT, which estimates and tests gene diversities and F-statistics, among other things; PCAGEN , which carries out Multivariate Analysis on genetic data. FSTAT and PCAGEN are no longer under development, but their functionalities are integrated step by step in the hierfstat package.

When applied to individuals, multivariate analysis allows the identification of clusters of individuals. I am currently investigating how a coupling of Multivariate analysis and clustering can help in identifying clusters of individuals.

Once the tools have been developed, they need testing. We are also investigating using computer simulations (e.g. quantiNEMO) how these tools perform. 

Estimating population history and selection with genetic markers

Collaborators: Samuel Neuenschwander, Sylvain Antoniazza, Ricardo Kanitz, Ludovic Dutoit


We use spatially explicit Approximate Bayesian Computation to infer the past history of different species (the barn owl, humans).  We used the inferred demo-genetic parameters in further simulations to assess the strength of selection on quantitative traits (in particular, whether the strong cline in colour observed across Europe in the barn owl could be the result of purely neutral processes), and attempt to infer the trait architecture.


We have also developed RAD-TAGs to estimate the population structure of the Miniopterus bat in Europe


Barn owl population genomics

Collaborators: Alexandre Roulin, Reto Burri (U. Uppsala, Sweden), Ioannis Xenarios (Vital-IT)


This project aims to develop genomic markers to gain a better understanding of the population biology and selective pressures acting on barn owls.  To this end, we intend to sequence the European barn owl genome, and develop a dense map of genetic markers in order to detect, using different scales (individual, pedigreed local population, european scale, worldwide scale) signature(s) of selection left in the genome. 

Soil metagenomics

Collaborators (PIs): Ian Sanders, Antoine Guisan, Marco Pagni (Vital-IT), Nicolas Guex (Vital-IT)


We investigated the fungal biodiversity of alpine soils using ca 200 permanent plots in the western Swiss Alps.  We used 454 sequencing and a new bio-informatic pipeline to analyse and cluster over 1 Million ITS sequences, and used this data to investigate how fungal species are distributed in the soil at different scales and whether this distribution can be linked to abiotic and/or biotic factors.

Multi locus interactions, population bottleneck and genetic variance

Collaborators: Guillaume Martin, Yamama Naciri-Graven (Geneva) and Alex Ding.

Both theoretical and empirical studies have pointed to the puzzling result that while bottlenecks (the reduction in size of a population) diminish genetic variability, in some cases they lead to an increase in additive genetic variance. Epistasis (the non-additive action of genes at different loci on one character) seems to play a major role. Using multilocus models, we are trying to understand
- What type of genotypic values lead to stable polymorphic equilibrium?
- Can multilocus epistasis help in maintaining additive genetic variance following bottlenecks ?

We've answered partially the last question (yes,it can!), but we need to add selection to the model. Also, matrices of genotypic values are generated at random for the moment, but eventually, we want to link our work with metabolic control theory.

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Burri R., Antoniazza S., Gaigher A., Ducrest A.L., Simon C., European Barn Owl Network, Fumagalli L., Fumagalli L., Goudet J., Roulin A., 2016. The genetic basis of color-related local adaptation in a ring-like colonization around the Mediterranean. Evolution 70(1) pp. 140-153. [Document] [DOI] [Web of Science] [Pubmed]
Kapun M., Fabian D.K., Goudet J., Flatt T., 2016. Genomic Evidence for Adaptive Inversion Clines in Drosophila melanogaster. Molecular Biology and Evolution 33 pp. 1317-1336. [DOI]
Montano V., Bertheau C., Dolezal P., Krumböck S., Okrouhlík J., StaufferC., Moodley Y., 2016. How differential management strategies affect Ips typographus L. dispersal. Forest Ecology and Management 360 pp. 195-204. [DOI] [Web of Science]
Rougemont Quentin, Roux Camille, Neuenschwander Samuel, Goudet Jerome, Launey Sophie, Evanno Guillaume, 2016. Reconstructing the demographic history of divergence between European river and brook lampreys using approximate Bayesian computations. PeerJ 4 pp. e1910. [DOI]
Brandt D.Y., Aguiar V.R., Bitarello B.D., Nunes K., Goudet J., Meyer D., 2015. Mapping Bias Overestimates Reference Allele Frequencies at the HLA Genes in the 1000 Genomes Project Phase I Data. G3 Genes Genomes Genetics 5(5) pp. 931-941. [DOI] [Web of Science] [Pubmed]
Masello J.F., Montano V., Quillfeldt P., Nuhlíčková S., Wikelski M., Moodley Y., 2015. The interplay of spatial and climatic landscapes in the genetic distribution of a South American parrot. Journal of Biogeography 42(6) pp. 1077-1090. [DOI] [Web of Science]
Montano V., Didelot X., Foll M., Linz B., Reinhardt R., Suerbaum S., Moodley Y., Jensen J.D., 2015. Worldwide Population Structure, Long-Term Demography, and Local Adaptation of Helicobacter pylori. Genetics 200(3) pp. 947-963. [DOI] [Web of Science] [Pubmed]
Witsenburg F., Clément L., López-Baucells A., Palmeirim J., Pavlinić I., Scaravelli D., ?evčík M., Dutoit L., Salamin N., Goudet J. et al., 2015. How a haemosporidian parasite of bats gets around: the genetic structure of a parasite, vector and host compared. Molecular Ecology 24(4) pp. 926-940. [Document] [DOI] [Web of Science] [Pubmed]
Alcala N., Goudet J., Vuilleumier S., 2014. Measuring genetic diversity and differentiation: what we can learn from GST and D? Theoretical Population Biology 94 pp. 74-84.
Alcala N., Goudet J., Vuilleumier S., 2014. On the transition of genetic differentiation from isolation to panmixia: What we can learn from GST and D. Theoretical Population Biology 93 pp. 75-84. [DOI] [Web of Science] [Pubmed]
Antoniazza S., Kanitz R., Neuenschwander S., Burri R., Gaigher A., Roulin A., Goudet J., 2014. Natural selection in a postglacial range expansion: the case of the colour cline in the European barn owl. Molecular Ecology 23(22) pp. 5508-5523. [DOI] [Web of Science] [Pubmed]
Blaser O., Neuenschwander S., Perrin N., 2014. Sex-chromosome turnovers: the hot-potato model. American Naturalist 183(1) pp. 140-146. [DOI] [Web of Science] [Pubmed]
Fodor A., Segura V., Denis M., Neuenschwander S., Fournier-Level A., Chatelet P., Homa F.A., Lacombe T., This P., Le Cunff L., 2014. Genome-Wide Prediction Methods in Highly Diverse and Heterozygous Species: Proof-of-Concept through Simulation in Grapevine. PLoS One 9(11) pp. e110436. [DOI] [Web of Science] [Pubmed]
Pajkovic M., Lappe S., Barman R., Parisod C., Neuenschwander S., Goudet J., Alvarez N., Guadagnuolo R., Felber F., Arrigo N., 2014. Wheat alleles introgress into selfing wild relatives: empirical estimates from approximate Bayesian computation in Aegilops triuncialis. Molecular Ecology 23(20) pp. 5089-5101. [embargo unspecified] [DOI] [Web of Science] [Pubmed]
Pellissier L., Niculita-Hirzel Hélène, Dubuis A., Pagni M., Guex N., Ndiribe C., Salamin N., Xenarios I., Goudet J., Sanders I.R. et al., 2014. Soil fungal communities of grasslands are environmentally structured at a regional scale in the Alps. Molecular Ecology 23(17) pp. 4274-4290. [DOI] [Web of Science] [Pubmed]
Alcala N., Streit D., Goudet J., Vuilleumier S., 2013. Peak and persistent excess of genetic diversity following an abrupt migration increase. Genetics 193(3) pp. 953-971. [DOI] [Web of Science] [Pubmed]
Blaser O., Grossen C., Neuenschwander S., Perrin N., 2013. Sex-chromosome turnovers induced by deleterious mutation load. Evolution 67(3) pp. 635-645. [DOI] [Web of Science] [Pubmed]
Delplancke M., Alvarez N., Benoit L., Espíndola A., I Joly H., Neuenschwander S., Arrigo N., 2013. Evolutionary history of almond tree domestication in the Mediterranean basin. Molecular Ecology 22(4) pp. 1092-1104. [DOI] [Web of Science] [Pubmed]
Pagni M., Niculita-Hirzel Hélène, Pellissier L., Dubuis A., Xenarios I., Guisan A., Sanders I.R., Goudet J., Guex N., 2013. Density-based hierarchical clustering of pyro-sequences on a large scale--the case of fungal ITS1. Bioinformatics 29(10) pp. 1268-1274. [Document] [DOI] [Web of Science] [Pubmed]
Pellissier L., Pinto-Figueroa E., Niculita-Hirzel Hélène, Moora M., Villard L., Goudet J., Guex N., Pagni M., Xenarios I., Sanders I. et al., 2013. Plant species distribution along environmental gradient: do belowground interactions with fungi matter? Frontiers in Plant Science 4(500) pp. 1-9. [Document] [DOI] [Web of Science] [Pubmed]
Dreiss A.N., Antoniazza S., Burri R., Fumagalli L., Sonnay C., Frey C., Goudet J., Roulin A., 2012. Local adaptation and matching habitat choice in female barn owls with respect to melanic coloration. Journal of Evolutionary Biology 25(1) pp. 103-114. [Document] [DOI] [Web of Science] [Pubmed]
Grossen C., Neuenschwander S., Perrin N., 2012. The balanced lethal system of crested newts: a ghost of sex chromosomes past? American Naturalist 180(6) pp. E174-E183. [DOI] [Web of Science] [Pubmed]
Grossen C., Neuenschwander S., Perrin N., 2012. The evolution of XY recombination: sexually antagonistic selection versus deleterious mutation load. Evolution 66(10) pp. 3155-3166. [DOI] [Web of Science] [Pubmed]
Kronholm I., Picó F.X., Alonso-Blanco C., Goudet J., de Meaux J., 2012. Genetic basis of adaptation in Arabidopsis thaliana: local adaptation at the seed dormancy QTL DOG1. Evolution 66(7) pp. 2287-2302. [DOI] [Web of Science] [Pubmed]
Mafli A., Goudet J., Farmer E.E., 2012. Plants and tortoises: mutations in the Arabidopsis jasmonate pathway increase feeding in a vertebrate herbivore. Molecular Ecology 21(10) pp. 2534-2541. [DOI] [Web of Science] [Pubmed]
van de Waal E., Krützen M., Hula J., Goudet J., Bshary R., 2012. Similarity in food cleaning techniques within matrilines in wild vervet monkeys. PLoS One 7(4) pp. e35694. [DOI] [Web of Science] [Pubmed]
Ascunce M.S., Yang C.C., Oakey J., Calcaterra L., Wu W.J., Shih C.J., Goudet J., Ross K.G., Shoemaker D., 2011. Global invasion history of the fire ant Solenopsis invicta. Science 331(6020) pp. 1066-1068. [DOI] [Web of Science] [Pubmed]
Barluenga M., Austerlitz F., Elzinga J.A., Teixeira S., Goudet J., Bernasconi G., 2011. Fine-scale spatial genetic structure and gene dispersal in Silene latifolia. Heredity 106(1) pp. 13-24. [DOI] [Web of Science] [Pubmed]
Blaser O., Neuenschwander S., Perrin N., 2011. On the maintenance of sex-chromosome polymorphism by sex-antagonistic selection. American Naturalist 178(4) pp. 515-524. [DOI] [Web of Science] [Pubmed]
Grossen C., Neuenschwander S., Perrin N., 2011. Temperature-dependent turnovers in sex-determination mechanisms: a quantitative model. Evolution 65(1) pp. 64-78. [DOI] [Web of Science] [Pubmed]
Meirmans P.G., Goudet J., IntraBioDiv Consortium, Gaggiotti O.E., Gaggiotti O.E., 2011. Ecology and life history affect different aspects of the population structure of 27 high-alpine plants. Molecular Ecology 20(15) pp. 3144-3155. [DOI] [Web of Science] [Pubmed]
Roulin A., Antoniazza S., Burri R., 2011. Spatial variation in the temporal change of male and female melanic ornamentation in the barn owl. Journal of Evolutionary Biology 24(7) pp. 1403-1409. [Document] [DOI] [Web of Science] [Pubmed]
Roulin A., Burri R., Antoniazza S., 2011. Owl melanin-based plumage redness is more frequent near than away from the equator: implications on the effect of climate change on biodiversity. Biological Journal of the Linnean Society 102(3) pp. 573-582. [Document] [DOI] [Web of Science]
Antoniazza S., Burri R., Fumagalli L., Goudet J., Roulin A., 2010. Local adaptation maintains clinal variation in melanin-based coloration of European barn owls (Tyto alba). Evolution 64(7) pp. 1944-1954. [embargo unspecified] [DOI] [Web of Science] [Pubmed]
Biollaz F., Bruyndonckx N., Beuneux G., Mucedda M., Goudet J., Christe P., 2010. Genetic isolation of insular populations of the Maghrebian bat, Myotis punicus, in the Mediterranean Basin. Journal of Biogeography 37(8) pp. 1557-1569. [DOI] [Web of Science]
Bruyndonckx N., Biollaz F., Dubey S., Goudet J., Christe P., 2010. Mites as biological tags of their hosts. Molecular Ecology 19(13) pp. 2770-2778. [Document] [DOI] [Web of Science] [Pubmed]
Thompson S.L., Lamothe M., Meirmans P.G., Périnet P., Isabel N., 2010. Repeated unidirectional introgression towards Populus balsamifera in contact zones of exotic and native poplars. Molecular ecology 19(1) pp. 132-145. [DOI] [Web of Science] [Pubmed]
Vuilleumier S., Goudet J., Perrin N., 2010. Evolution in heterogeneous populations: from migration models to fixation probabilities. Theoretical Population Biology 78(4) pp. 250-258. [DOI] [Web of Science] [Pubmed]
Wegmann D., Leuenberger C., Neuenschwander S., Excoffier L., 2010. ABCtoolbox: a versatile toolkit for approximate Bayesian computations. BMC Bioinformatics 11(1) p. 116. [Document] [DOI] [Web of Science] [Pubmed]
Broquet T., Yearsley J., Hirzel A.H., Goudet J., Perrin N., 2009. Inferring recent migration rates from individual genotypes. Molecular Ecology 18(6) pp. 1048-1060. [Document] [DOI] [Web of Science] [Pubmed]
Escobar J. S., Facon B., Jarne P., Goudet J., David P., 2009. Correlated evolution of mating strategy and inbreeding depression within and among populations of the hermaphroditic snail Physa acuta. Evolution 63(11) pp. 2790-2804. [embargo unspecified] [DOI] [Web of Science]
Evanno G., Castella E., Antoine C., Paillat G., Goudet J., 2009. Parallel changes in genetic diversity and species diversity following a natural disturbance. Molecular Ecology 18(6) pp. 1137-1144. [Document] [DOI] [Web of Science] [Pubmed]
Henry P., Le Lay G., Goudet J., Guisan A., Jahodová S., Besnard G., 2009. Reduced genetic diversity, increased isolation and multiple introductions of invasive giant hogweed in the western Swiss Alps. Molecular Ecology 18(13) pp. 2819-2831. [embargo unspecified] [DOI] [Web of Science] [Pubmed]
Meirmans P.G., Bousquet J., Isabel N., 2009. A metapopulation model for the introgression from genetically modified plants into their wild relatives. Evolutionary Applications 2(2) pp. 160-171. [DOI] [Web of Science]
Romero I.G., Manica A., Goudet J., Handley L.L., Balloux F., 2009. How accurate is the current picture of human genetic variation? Heredity 102(2) pp. 120-126. [DOI] [Web of Science] [Pubmed]
Facon B., Ravigne V., Goudet J., 2008. Gender-role alternation in the simultaneously hermaphroditic freshwater snail Physa acuta: not with the same partner. Behavioral Ecology and Sociobiology 62(5) pp. 713-720. [Document] [DOI] [Web of Science]
Fagundes N J R, Ray N, Beaumont M, Neuenschwander S, Salzano F M, Bonatto S L & Excoffier L, 2008. Reply: Reply to Garrigan and Hammer: Ancient lineages and assimilation. Proceedings of the National Academy of Sciences USA 105 pp. E4.
Neuenschwander S Largiadèr CR Ray N Currat M Vonlanthen P Excoffier Laurent, 2008. Colonization history of the Swiss Rhine basin by the bullhead (Cottus gobio): Inference under a Bayesian spatially explicit framework. Molecular Ecology 17(3) pp. 757-772. [DOI] [Web of Science]
Neuenschwander S., Hospital F., Guillaume F., Goudet J., 2008. quantiNemo: an individual-based program to simulate quantitative traits with explicit genetic architecture in a dynamic metapopulation. Bioinformatics 24(13) pp. 1552-1553. [DOI] [Web of Science] [Pubmed]
David P., Pujol B., Viard F., Castella V., Goudet J., 2007. Reliable selfing rate estimates from imperfect population genetic data. Molecular Ecology 16(12) pp. 2474-2487. [Document] [DOI] [Web of Science] [Pubmed]
de Meeûs T., Goudet J., 2007. A step-by-step tutorial to use HierFstat to analyse populations hierarchically structured at multiple levels. Infection, Genetics and Evolution 7(6) pp. 731-735. [Document] [DOI] [Web of Science] [Pubmed]
Facon B., Sauteur L., Ravigne V., Goudet J., 2007. Effect of mating history on gender preference in the hermaphroditic snail physa acuta. Animal Behaviour 74(5) pp. 1455-1461. [Document] [DOI] [Web of Science]
Fagundes N.J., Ray N., Beaumont M., Neuenschwander S., Salzano F.M., Bonatto S.L., Excoffier L., 2007. Statistical evaluation of alternative models of human evolution. Proceedings of the National Academy of Sciences of the United States of America 104(45) pp. 17614-17619. [DOI] [Web of Science] [Pubmed]
Handley L.J., Manica A., Goudet J., Balloux F., 2007. Going the distance: human population genetics in a clinal world. Trends in Genetics 23(9) pp. 432-439. [Document] [DOI] [Web of Science] [Pubmed]
Martin G., Elena S.F., Lenormand T., 2007. Distributions of epistasis in microbes fit predictions from a fitness landscape model. Nature Genetics 39(4) pp. 555-560. [Document] [DOI] [Web of Science] [Pubmed]
Vonlanthen P., Excoffier L., Bittner D., Persat H., Neuenschwander S., Largiadèr C.R., 2007. Genetic analysis of potential postglacial watershed crossings in Central Europe by the bullhead (Cottus gobio L.). Molecular Ecology 16(21) pp. 4572-4584. [DOI] [Web of Science] [Pubmed]
Evanno G., Castella E., Goudet J., 2006. Evolutionary aspects of population structure for molecular and quantitative traits in the freshwater snail Radix balthica. Journal of Evolutionary Biology 19(4) pp. 1071-1082. [Document] [DOI] [Web of Science] [Pubmed]
Facon B., Ravigne V., Goudet J., 2006. Experimental evidence of inbreeding avoidance in the hermaphroditic snail Physa acuta. Evolutionary Ecology 20(5) pp. 395-406. [Document] [DOI] [Web of Science]
Glaettli M., Pescatore L., Goudet J., 2006. Proximity-dependent pollen performance in Silene vulgaris. Annals of Botany 98(2) pp. 431-437. [Document] [DOI] [Web of Science] [Pubmed]
Guillaume F., Rougemont J., 2006. Nemo: An evolutionary and population genetics programming framework. Bioinformatics - Applications Note 22(20) pp. 2556-2557. [Document]
Ding A., Goudet J., 2005. Heterozygote advantage and the maintenance of polymorphism for multilocus traits. Theoretical Population Biology 68(3) pp. 157-166. [Document] [DOI] [Web of Science] [Pubmed]
Evanno G., Regnaut S., Goudet J., 2005. Detecting the number of clusters of individuals using the software STRUCTURE: a simulation study. Molecular Ecology 14(8) pp. 2611-2620. [Document] [DOI] [Web of Science] [Pubmed]
Goudet J., 2005. HIERFSTAT, a package for R to compute and test hierarchical F-statistics. Molecular Ecology Notes 5(1) pp. 184-186. [Document] [DOI] [Web of Science]
McCoy K. D., Chapuis E., Tirard C., Boulinier T., Michalakis Y., Le Bohec C., Le Maho Y., Gauthier-Clerc M., 2005. Recurrent evolution of host-specialized races in a globally distributed parasite. Proceedings of the Royal Society of London. Series B. 272 pp. 2389-2395. [Document]
Trouve S., Degen L., Goudet J., 2005. Ecological components and evolution of selfing in the freshwater snail Galba truncatula. Journal of Evolutionary Biology 18(2) pp. 358-370. [Document] [DOI] [Web of Science] [Pubmed]
Koch A.M., Kuhn G., Fontanillas P., Fumagalli L., Goudet J., Sanders I.R., 2004. High genetic variability and low local diversity in a population of arbuscular mycorrhizal fungi. Proceedings of the National Academy of Sciences of the United States of America 101(8) pp. 2369-2374. [DOI] [Web of Science] [Pubmed]
Trouve S., Ding A., Goudet J., 2004. Synergistic epistasis and alternative hypotheses. Journal of Evolutionary Biology 17(6) pp. 1400-1401. [Document] [DOI] [Web of Science] [Pubmed]
Juillet N., Freymond H., Degen L., Goudet J., 2003. Isolation and characterization of highly polymorphic microsatellite loci in the bladder campion, Silene vulgaris (Caryophyllaceae). Molecular Ecology Notes 3(3) pp. 358-359. [DOI] [Web of Science]
Trouvé S., Degen L., Renaud F., Goudet J., 2003. Evolutionary implications of a high selfing rate in the freshwater snail Lymnaea truncatula. Evolution 57(10) pp. 2303-2314. [Document] [DOI] [Web of Science] [Pubmed]
Balloux F., Lugon-Moulin N., 02-2002. The estimation of population differentiation with microsatellite markers. Molecular Ecology 11(2) pp. 155-165. [DOI] [Web of Science]
Goudet J., Keller L., 2002. The correlation between inbreeding and fitness: does allele size matter? Trends in Ecology and Evolution 17(5) pp. 201-202. [Document] [DOI] [Web of Science]
Goudet J., Perrin N., Waser P., 2002. Tests for sex-biased dispersal using bi-parentally inherited genetic markers. Molecular Ecology 11(6) pp. 1103-1114. [Document] [DOI] [Web of Science] [Pubmed]
Perrin N., Goudet J., 2001. Inbreeding, kinship, and the evolution of natal dispersal. pp. 123-142 in Clobert J. et al. (eds.) Dispersal. Oxford University Press, Oxford. [Document]
Balloux F., Brünner H., Lugon-Moulin N., Hausser J., Goudet J., 2000. Microsatellites can be misleading: an empirical and simulation study. Evolution 54(4) pp. 1414-1422. [Document] [DOI] [Web of Science] [Pubmed]
Trouvé S., Degen L., Meunier C., Tirard C., Hurtrez-Boussès S., Durand P., Guégan J.F., Goudet J., Renaud F., 2000. Microsatellites in the hermaphroditic snail, Lymnaea truncatula, intermediate host of the liver fluke, Fasciola hepatica. Molecular Ecology 9(10) pp. 1662-1664. [DOI] [Web of Science] [Pubmed]
Letocart M., Boerlin P., Boerlin-Petzold F., Goudet J., Baranton G., Perolat P., 1999. Genetic structure of the genus Leptospira by multilocus enzyme electrophoresis. International Journal of Systematic Bacteriology 49(1) pp. 231-238. [DOI] [Web of Science]
Lugon-Moulin N., Brunner H., Balloux F., Hausser J., Goudet J., 1999. Do riverine barriers, history or introgression shape the genetic structuring of a common shrew (Sorex araneus) population? Heredity 83(2) pp. 155-161. [Document] [DOI] [Web of Science] [Pubmed]
Lugon-Moulin N., Brunner H., Wyttenbach A., Hausser J., Goudet J., 1999. Hierarchical analyses of genetic differentiation in a hybrid zone of Sorex araneus (Insectivora : Soricidae). Molecular Ecology 8(3) pp. 419-431. [Document] [DOI] [Web of Science]
Wyttenbach A., Goudet J., Cornuet J. M., Hausser J., 1999. Microsatellite variation reveals low genetic subdivision in a chromosome race of Sorex araneus (Mammalia, Insectivora). Journal of Heredity 90(2) pp. 323-327. [DOI] [Web of Science]
Balloux F., Ecoffey E., Fumagalli L., Goudet J., Wyttenbach A., Hausser J., 1998. Microsatellite conservation, polymorphism, and GC content in shrews of the genus Sorex (Insectivora, Mammalia). Molecular Biology and Evolution 15(4) pp. 473-475. [Document] [Web of Science] [Pubmed]
Balloux F., Goudet J., Perrin N., 1998. Breeding system and genetic variance in the monogamous, semi-social shrew, Crocidura russula. Evolution 52(4) pp. 1230-1235. [Document] [Web of Science]
Giles B. E., Lundqvist E., Goudet J., 1998. Restricted gene flow and subpopulation differentiation in Silene dioica. Heredity 80(6) pp. 715-723. [Document] [DOI] [Web of Science]
Savolainen V., Goudet J., 1998. Rate of gene sequence evolution and species diversification in flowering plants: a re-evaluation. Proceedings of the Royal Society of London Series B-Biological Sciences 265(1396) pp. 603-607. [Document] [DOI] [Web of Science]
Favre L., Balloux F., Goudet J., Perrin N., 1997. Female-biased dispersal in the monogamous mammal Crocidura russula: evidence from field data and microsatellite patterns. Proceedings of the Royal Society of London Series B-Biological Sciences 264(1378) pp. 127-132. [Document] [DOI] [Web of Science] [Pubmed]
Giles B. E., Goudet J., 1997. Case study of genetic structure in a plant metapopulation. pp. 429-454 in Hanski I., Gilpin M. E. (eds.) Metapopulation biology : ecology, genetics, and evolution. Academic Press, San Diego.
Boerlin P., Boerlin-Petzold F., Goudet J., Durussel C., Pagani J.L., Chave J.P., Bille J., 1996. Typing Candida albicans oral isolates from human immunodeficiency virus-infected patients by multilocus enzyme electrophoresis and DNA fingerprinting. Journal of Clinical Microbiology 34(5) pp. 1235-1248. [Web of Science] [Pubmed]
Estoup A., Solignac M., Cornuet J.M., Goudet J., Scholl A., 1996. Genetic differentiation of continental and island populations of Bombus terrestris (Hymenoptera: Apidae) in Europe. Molecular Ecology 5(1) pp. 19-31. [DOI] [Web of Science] [Pubmed]
Goudet J., Raymond M., de Meeûs T., Rousset F., 1996. Testing differentiation in diploid populations. Genetics 144(4) pp. 1933-1940. [Document] [Web of Science] [Pubmed]
Lugon-Moulin N., Wyttenbach A., Brunner H., Goudet J., Hausser J., 1996. Study of gene flow through a hybrid zone in the common shrew (Sorex araneus) using microsatellites. Hereditas 125(2-3) pp. 159-168. [DOI] [Web of Science]
Raybould A. F., Goudet J., Mogg R. J., Gliddon C. J., Gray A. J., 1996. Genetic structure of a linear population of Beta vulgaris ssp maritima (sea beet) revealed by isozyme and RFLP analysis. Heredity 76(2) pp. 111-117. [DOI] [Web of Science]
Goudet J., 1995. FSTAT (Version 1.2): A computer program to calculate F-statistics. Journal of Heredity 86(6) pp. 485-486. [Web of Science]
Perrin N., Keller L., Goudet J., 1994. Evolution in structured populations. Bulletin de la Société Vaudoise de Sciences Naturelles 83(2) pp. 153-174.
Phd thesis
ANTONIAZZA S., 12-2014. GENETIC ARCHITECTURE, EVOLUTION AND MAINTENANCE OF A COLOR CLINE AT A CONTINENTAL SCALE. Université de Lausanne, Faculté de biologie et médecine, Goudet J. (dir.). [Document]
Kanitz R., 07-2014. THE USE OF SIMULATIONS IN EVOLUTIONARY POPULATION GENETICS: APPLICATIONS ON HUMANS, OWLS AND VIRTUAL ORGANISMS. 170 p., Université de Lausanne, Faculté de biologie et médecine, Goudet J. (dir.). [Document]
Zaheri M., 2014. KCM, a general framework for codon-based model of evolution. 118 p., Université de Lausanne, Faculté de biologie et médecine, Salamin N., Goudet J. (dir.).
Internicola A., 2008. On the success of generalized food deception in orchids : the role of sympatric rewarding species and pollinators. 148 p., Université de Lausanne, Faculté de biologie et médecine, Gigord L. (dir.).
Randin C., 2007. Providing more informative projections of climate change impact on plant distribution in a mountain environment. 252 p., Université de Lausanne, Faculté de biologie et médecine, Guisan A. (dir.).
Teixeira S., 2007. Multiple paternity and its consequences in the white campion " Silene latifolia ". 132 p., Université de Lausanne, Faculté de biologie et médecine, Bernasconi G. (dir.).
Chapuis E., 2006. Local adaptation and life history traits evolution in heterogeneous environment : an empirical example in the freshwater snail, Galba truncatula. 129 p., Université de Lausanne, Faculté de biologie et médecine, Goudet J. (dir.).
Evanno G., 2006. Linking genetic and species diversities in a community of freshwater gastropods. 97 p., Université de Lausanne, Faculté de biologie et médecine, Goudet J. (dir.).
Juillet N., 2006. Evolutionary ecology of the colour-dimorphic rewardless orchid "Dactylorhiza sambucina". 114 p., Université de Lausanne, Faculté de biologie et médecine, Gigord L. (dir.).
Ding A., 2005. Maintenance of polymorphism : a theoretical approach using multilocus systems. 72 p., Université de Lausanne, Faculté de biologie et médecine, Goudet J. (dir.).
Glaettli M., 2004. Mechanisms involved in the maintenance of inbreeding depression in gynodioecious "Silene vulgaris" (Caryophyllaceae): an experimental investigation. 118 p., Université de Lausanne, Faculté de biologie et médecine, Goudet J. (dir.).


Jérôme Goudet
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Fax: +4121 692 4265

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