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Division of Experimental Oncology


2004 | 2003 | 2002 | 2001 | 2000


Vuadens F, Rufer N, Kress A, Corthésy P, Schneider P and Tissot J-D. Identification of swiprosin 1 in human lymphocytes. Proteomics. 4(8):2216-20. 2004  PubMed 

Zippelius A, Batard P, Rubio-Godoy V, Bioley G, Liénard D, Lejeune F, Rimoldi D, Guillaume P, Meidenbauer N, Mackensen A, Rufer N, Speiser D, Cerottini J-C, Romero P and Pittet MJ. Effector function of human tumor-specific CD8 T cells in melanoma lesions: a state of local functional tolerance. Cancer Research. 64(8):2865-73. 2004  PubMed

Zippelius A, Bioley G, Le Gal F-A, Rufer N, Brandes M, Batard P, De Smedt M, Plum J, Speiser D, Cerottini J-C, Dietrich P-Y, Romero P and Pittet M. Human thymus exports naive CD8 T cells that can home to nonlymphoid tissues. J Immunol. 172(5):2773-77. 2004  PubMed

Papagno L, Spina CA, Marchant A, Salio M, Rufer N, Little S, Dong T, Chesney G, Waters A, Easterbrook P, Dunbar PR, Shepherd D, Cerundolo V, Emery V, Griffiths P, Conlon C, McMichael AJ, Richman DD, Rowland-Jones SL and Appay V. CD8+ T-cell differentiation towards senescence following elevated activation in HIV-1 infection. PLoS Biol. 2(2):E20. 2004  PubMed




Rufer N, Zippelius A, Batard P, Pittet MJ, Kurth I, Corthesy P, Cerottini J-C, Leyvraz S, Roosnek E, Nabholz M and Romero P. Ex-vivo characterization of human CD8+ T subsets with distinct replicative history and partial effector functions. Blood. 102(5):1779-87. 2003  PubMed 

Sauce D, Rufer N, Mercier P, Bodinier M, Rémy-Martin J-P, Duperrier A, Ferrand C, Hervé P, Romero P, Lang F, Tiberghien P and Robinet E. Retrovirus-mediated gene transfer in polyclonal T cells results in lower apoptosis and enhanced ex vivo expansion of CMV-reactive CD8 T cells as compared to EBV-reactive CD8 T cells. Blood. 102(4):1241-8. 2003  PubMed

Rufer N and Nabholz M. Télomérase, élixir de jouvence des cellules humaines? Médecine/Science. 19(3):345-50. 2003  PubMed

Bigouret V, Hoffmann T, Arlettaz L, Villard J, Colonna M, Ticheli A, Gratwohl A, Samii K, Chapuis B, Rufer N and Roosnek E. Monoclonal T cell expansions in asymptomatic individuals and in patients with Large Granular Leukemia consist of cytotoxic effector T cells expressing the activating CD94-NKG2C/E and NKG2D Killer Cell Receptors. Blood. 101(8):3198-3204. 2003  PubMed




Romero P, Valmori D, Pittet MJ, Zippelius A, Rimoldi A, Levy F, Dutoit V, Ayyoub M, Rubio-Godoy V, Michielin O, Guillaume P, Batard P, Luescher IF, Lejeune F, Lienard D, Rufer N, Dietrich PY, Speiser DE, Cerottini JC. Antigenicity and immunogenicity of Melan-A/Mart-1 derived peptides as targets for tumor reactive CTL in human melanoma. Immunol Rev. 188:81-96. 2002  PubMed 

Einsele H, Roosnek E, Rufer N, Sinzger C, Riegler S, Löffler J, Grigoleit U, Morris A, Rammensee H-G, Kanz L, Kleihauer A, Frank F, Jahn G and Hebart H. Infusion of cytomegalovirus (CMV)-specific T cells for the treatment of CMV infection not responding to antiviral chemotherapy. Blood. 99:3916-22. 2002  PubMed

Kwak BR, Myit S, Mulhaupt F, Veillard N, Rufer N, Roosnek E and Mach F. PPARgamma but not PPARalpha ligands are potent repressors of major histocompatibility complex class II induction in atheroma-associated cells. Circ Res. 90(3):356-22. 2002  PubMed

Zippelius A, Pittet MJ, Batard P, Rufer N, de Smedt M, Guillaume P, Ellefsen K, Valmori D, Lienard D, Plum J, MacDonald RH, Speiser DE, Cerottini J-C and Romero P. Thymic selection generates a large T cell pool recognizing a self-peptide in humans. J Exp Med. 195:485-94. 2002  PubMed




Rufer N, Migliaccio M, Antonchuk J, Humphries RK, Roosnek E and Lansdorp PM. Transfer of the human telomerase reverse transcriptase (TERT) gene into T lymphocytes results in extension of replicative potential. Blood 98:597-603. 2001  PubMed 

Brümmendorf TH, Rufer N, Holyoake TL, Maciejewski J, Barnett MJ, Eaves CJ, Eaves AC, Young N and Lansdorp PM. Telomere length dynamics in normal individuals and in patients with hematopoietic stem cell-associated disorders. Ann N Y Acad Sci 938:293-303. 2001  PubMed

Brümmendorf TH, Rufer N, Baerlocher GM, Roosnek E and Lansdorp PM. Limited telomere shortening in hematopoietic stem cells after transplantation. Ann N Y Acad Sci 938:1-7. 2001  PubMed

Rufer N, Helg C, Chapuis B and Roosnek E. Human memory T cells: lessons from stem cell transplantation. Trends Immunol 22(3):136-41. 2001  PubMed

Rufer N, Brümmendorf TH, Chapuis B, Helg C, Lansdorp PM and Roosnek E. Accelerated telomere shortening in hematological lineages is limited to the first year following stem cell transplantation. Blood 97:575-7. 2001  PubMed




Batliwalla F, Rufer N, Lansdorp PM and Gregersen PK. Oligoclonal expansions in the CD8+CD28- T cells largely explain the shorter telomeres detected in this subset: analysis by flow FISH. Hum Immunol 61:951-8. 2000  PubMed 

Brümmendorf TH, Holyoake TL, Rufer N, Barnett MJ, Schulzer M, Eaves CJ, Eaves AC and Lansdorp PM. Prognostic implications of differences in telomere length between normal and malignant cells from patients with chronic myeloid leukemia measured by flow cytometry. Blood 95:1883-90. 2000  PubMed



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