Publications 2000-2004

Karkkainen, M., and Petrova, T.V. (2000) Vascular endothelial growth factor receptors in the regulation of angiogenesis and lymphangiogenesis Oncogene, 19, 5598-605.

Koppal, T., Petrova, T.V., and Van Eldik, L.J. (2000) Cyclopentenone prostaglandin 15-deoxy-Delta(12,14)-prostaglandin J(2) acts as a general inhibitor of inflammatory responses in activated BV-2 microglial cells. Brain Res., 867, 115-121. PubMed

Petrova, T.V., Hu, J., and Van Eldik, L.J. (2000) Modulation of glial activation by astrocyte-derived protein S100B: differential responses of astrocyte and microglial cultures. Brain Res., 853, 74-80. PubMed

Veikkola T., Jussila L., Makinen T., Karpanen T., Jeltsch M., Petrova T.V., Kubo H., Thurston G., McDonald D.M., Achen M.G., Stacker, S.A., Alitalo K. (2001) Signalling via vascular endothelial growth factor receptor-3 is sufficient for lymphangiogenesis in transgenic mice EMBO J. 20, 1223-31. PubMed

Baladi S., Tsvetkov P.O., Petrova T.V., Takagi T., Sakamoto H., Lobachov V.M., Makarov A.A., and Cox JA. (2001) Folding units in calcium vector protein of amphioxus: Structural and functional properties of its  amino- and carboxy-terminal halves. Protein Sci. 10, 771-8. PubMed

Petrova T.V, Makinen T, Makela TP, Saarela J, Virtanen I, Ferrell RE, Finegold DN, Kerjaschki D, Yla-Herttuala S, and Alitalo K. (2002) Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factor.  EMBO J. 21, 4593-4599. PubMed

Iljin, K., Petrova, T.V., Veikkola, T., Kumar, V., Poutanen, M., and Alitalo, K (2002) A fluorescent Tie1 reporter allows monitoring of vascular development and endothelial cell isolation from transgenic mouse embryos.  FASEB J. 16, 1764-1774. PubMed

Petrova TV, Karpanen T, Norrmen C, Mellor R, Tamakoshi T, Finegold D, Ferrell R, Kerjaschki D, Mortimer P, Yla-Herttuala S, Miura N, Alitalo K. (2004) Defective valves and abnormal mural cell recruitment underlie lymphatic vascular failure in lymphedema distichiasis. Nature Medicine, 10, 974-981. PubMed

Kerjaschki, D., Regele, H.M., Moosberger, I., Nagy-Bojarski, K., Watschinger, B., Soleiman, A., Birner , P., Krieger, S., Hovorka, A., Silberhumer, G., Laakkonen, P., Petrova, T., Langer, B., Raab, I.  (2004) Lymphatic neoangiogenesis in human kidney transplants is associated with immunologically active lymphocytic infiltrates.  J. Am. Soc Nephrol.,  15, 603-12. PubMed

Karkkainen, M. J., Haiko, P., Sainio, K., Partanen, J., Taipale, J., Petrova, T., Jeltsch, M., Jackson, D. G., Talikka, M., Rauvala, H., Betsholtz, C., and Alitalo, K. (2004) VEGF-C is required for sprouting of the first lymphatic vessels from embryonic veins.  Nature Immunology, 5, 74-80 PubMed

Veikkola,T., Lohela, M., Ikenberg, K., Mäkinen, T., Korff, T.,Saaristo,  Petrova T.,  A., Jeltsch,M., Augustin, H.G., and Alitalo, K. (2004) Intrinsic versus microenvironmental regulation of lymphatic endothelial cell phenotype and function.  FASEB J., 17, 2006-2013.  PubMed