Several projects conducted in the laboratory are based on clinically relevant questions, with the goal to be able to develop new strategies aimed at improving cancer management and patient quality of live, though improved cancer diagnosis, therapy and monitoring.
We are collaborating with several local, national and international cancer centers to design, perform and analyze clinical-laboratory (translational) studies aimed at testing and validating hypothesis based on results generated in the laboratory. Currently ongoing studies include:
- Early cancer detection though cellular and molecular monitoring or the host response to tumors or precancerous lesions
- Monitoring tumor angiogenesis and antiangiogenic therapies though molecular, cellular and functional imaging approaches;
- Testing the effect of therapeutic interventions (such as radiotherapy, chemotherapy or targeted antitumor therapy) on tumor stroma and bone marrow-derived cells.