My research interests concern the mechanisms of nasal carriage of Staphylococcus aureus.
The nose is the main ecological niche where S. aureus resides, but factors implicated by nasal carriage are not fully known. The mechanisms leading to S. aureus nasal carriage could be related to several factors, such as bacterial surface properties, genetic predisposition of the host and/or a peculiar microbial environment, including the presence of bacteria and viruses.
My work focuses on human nasal microbiota, I use molecular techniques employed in microbial ecology to appraise whether a specific pattern of microbial environment is associated with carriage of S. aureus.
April 2008 -
Postdoctoral Research Associate at the Department of Fundamental Microbiology (group Philippe Moreillon, University of Lausanne, Switzerland)
Subject: Metagenomic approach to determine the nasal micro-environment of S. aureus human healthy carriers and non-carriers
2006 - 2007
Research associate at the Microbiology Unit of the French National Institute for Agronomical Research (INRA), Clermont-Ferrand, France. «Genoferment» ANR French research program
Subject: Evaluation of genomic diversity of S. xylosus strains and in situ gene expression of Staphylococcus xylosus
2003 - 2006
Ph.D. Microbiology Unit, INRA, Clermont-Ferrand, France
Subject: «Genomic of Staphylococcus xylosus»
- Physical and genetic map of Staphylococcus xylosus
- Participation in the Staphylococcus xylosus C2a strain genome sequencing project
- Suppressive and subtractive hybridization between S. xylosus strains from various ecological niches
January - July 2003
Master degree internship at the Meat Research Unit (SRV) INRA, Clermont-Ferrand, France
Subject: «Synthesis of aromatic compounds by Staphylococcus carnosus in fermented meat products: leucine catabolism»
April - June 2002
Voluntary internship at the Purpan Hospital (Toulouse), Dr Prère's Laboratory
Subject: «Characterization of Escherichia coli responsible of hemolytic and uremic syndromes and of acute pyelonephritis by multiplex PCR»
Dordet-Frisoni E., Talon R., Leroy S. Surface migration of Staphylococcus xylosuson low-agar media. Res Microbiol, 2008 March ; 159; 263-269.
Dordet-Frisoni E., Géraud Dorchies, Cécilia De Araujo, Talon R., Leroy S. Genomic diversity in Staphylococcus xylosusspecies. Appl Environ Microbiol 2007 Nov; 73(22):7199-7209.
Dordet-Frisoni E., Talon R., Leroy S. Physical and genetic map of the Staphylococcus xylosus C2a chromosome. FEMS Microbiol Lett. 2007 Jan; 266(2):184-93.
Planchon S., Gaillard-Martinie B., Dordet-Frisoni E., Bellon-Fontaine M.N., Leroy S., Labadie J., Hebraud M., Talon R. Formation of Biofilm by Staphylococcus xylosus. Int J Food Microbiol. 2006 May 25;109(1-2):88-96.
Champomier-Vergès M., CrutzLe Coq A.M., Zagorec M., Leroy S., Dordet-Frisoni E., Planchon S., Talon R. 2007. Genetics of microbial starters. In: Handbook of Fermented Meat and Poultry, Eds F. Toldra, Wai-Kit Nip, J.G. Sebranek, L.H. Stahnke, Expedito-Tadeu F. Silveira and R. Talon and Y.H. Hui. Chapter 17.