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In Press
Eggimann P., Que Y.A., Revelly J.P., Pagani J.L., In Press. Preventing invasive candida infections. Where could we do better? Journal of Hospital Infection . [DOI] [Pubmed]
Hazan R, Que YA, Maura D, Strobel B, Majcherczyk PA, Hopper LR, Wilburg DJ, Hrehah TN, Barquera B, Rahme LG, In Press. Auto Poisoning of the Respiratory Chain by a Quorum Sensing Regulated Molecule Favors Biofilm Formation and Antibiotic Tolerance. Current Biology .
Eggimann P, Pagani JL, Seravalli L, Revelly JP, Que YA, 2015. Nouvelles stratégies dans la prise en charge: Infections complexes en médecine intensive. Forum Medical Suisse 15(6) pp. 124-128. [url editor site]
Eggimann P., Que Y.A., Revelly J.P., Pagani J.L., 2015. Preventing invasive candida infections. Where could we do better? Journal of Hospital Infection 89(4) pp. 302-308. [DOI] [Web of Science] [Pubmed]
Fournier A, Eggimann P, Pantet O, Krähenbühl M, Bonnemain C-L, Fournier C, Pagani J-L, Revelly J-P, Dupuis-Lozeron E, Sadeghipour F et al., 2015. Antibiotics' consumption to early detect epidemics of P. aeruginosa in a burn center: a paradigm shift in the epidemiological surveillance of nosocomial infections. pp. P232 in 3rd International Conference on Prevention and Infection Control (ICPIC 2015). Antimicrobial Resistance and Infection Control 4(Suppl 1). [DOI]
Fournier A., Eggimann P., Pagani J.L., Revelly J.P., Decosterd L.A., Marchetti O., Pannatier A., Voirol P., Que Y.A., 2015. Impact of the introduction of real-time therapeutic drug monitoring on empirical doses of carbapenems in critically ill burn patients. Burns 41(5) pp. 956-968. [DOI] [Web of Science] [Pubmed]
Fournier A., Pantet O., Guerid S., Eggimann P., Pagani J.L., Revelly J.P., Hauser P.M., Marchetti O., Fontanella S., Letovanec I. et al., 2015. Effective Treatment of Invasive Aspergillus fumigatus Infection Using Combinations of Topical and Systemic Antifungals in a Severely Burned Patient. Journal of Burn Care and Research 36(2) pp. e85-e89. [DOI] [Web of Science] [Pubmed]
Khalifa L., Brosh Y., Gelman D., Coppenhagen-Glazer S., Beyth S., Poradosu-Cohen R., Que Y.A., Beyth N., Hazan R., 2015. Targeting Enterococcus faecalis Biofilms with Phage Therapy. Applied and Environmental Microbiology 81(8) pp. 2696-2705. [DOI] [Web of Science] [Pubmed]
Pagani Jean-Luc, Revelly Jean-Pierre, Que Yok-Ai, Eggimann Philippe, 2015. The Role of Biomarkers for Starting Antifungals in the Intensive Care Unit. Clinical Pulmonary Medicine 22(6) pp. 286-293. [DOI]
Que Y.A., Guessous I., Dupuis-Lozeron E., Alves de Oliveira C.R., Ferreira Oliveir C., Graf R., Seematter G., Revelly J.P., Pagani J.L., Liaudet L. et al., 2015. Prognostication of Mortality in Critically Ill Patients With Severe Infections. Chest 148(3) pp. 674-682. [DOI] [Web of Science] [Pubmed]
Que Y.A., Moreillon P., 2015. Staphylococcus aureus (Including Staphylococcal toxic shock). pp. 2237-2271 in Bennett J.E., Dolin R., Blaser M.J. (eds.) Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 8th Ed., Saunders.
Que Y.A., Virgini V., Lozeron E.D., Paratte G., Prod'hom G., Revelly J.P., Pagani J.L., Charbonney E., Eggimann P., 2015. Low C-reactive protein values at admission predict mortality in patients with severe community-acquired pneumonia caused by Streptococcus pneumoniae that require intensive care management. Infection 43(2) pp. 193-199. [DOI] [Web of Science] [Pubmed]
Tsurumi A., Que Y.A., Yan S., Tompkins R.G., Rahme L.G., Ryan C.M., 2015. Do standard burn mortality formulae work on a population of severely burned children and adults? Burns 41(5) pp. 935-945. [DOI] [Web of Science] [Pubmed]
Veloso T.R., Mancini S., Giddey M., Vouillamoz J., Que Y.A., Moreillon P., Entenza J.M., 2015. Vaccination against Staphylococcus aureus experimental endocarditis using recombinant Lactococcus lactis expressing ClfA or FnbpA. Vaccine 33(30) pp. 3512-3517. [DOI] [Web of Science] [Pubmed]
Veloso T.R., Oechslin F., Que Y.A., Moreillon P., Entenza J.M., Mancini S., 2015. Aspirin plus ticlopidine prevented experimental endocarditis due to Enterococcus faecalis and Streptococcus gallolyticus. Pathogens and Disease 73(8) pp. ftv060. [DOI] [Web of Science] [Pubmed]
Veloso T.R., Que Y.A., Chaouch A., Giddey M., Vouillamoz J., Rousson V., Moreillon P., Entenza J.M., 2015. Prophylaxis of experimental endocarditis with antiplatelet and antithrombin agents : a role for long-term prevention of infective endocarditis in humans? Journal of Infectious Diseases 211(1) pp. 72-79. [DOI] [Web of Science] [Pubmed]
Veloso T.R., Que Y.A., Moreillon P., Entenza J.M., 2015. Reply to Eisen and McBryde. Journal of Infectious Diseases 212(4) pp. 674-675. [DOI] [Web of Science] [Pubmed]
Yan S., Tsurumi A., Que Y.A., Ryan C.M., Bandyopadhaya A., Morgan A.A., Flaherty P.J., Tompkins R.G., Rahme L.G., 2015. Prediction of multiple infections after severe burn trauma: a prospective cohort study. Annals of Surgery 261(4) pp. 781-792. [DOI] [Web of Science] [Pubmed]
Bonafé L., Berger M.M., Que Y.A., Mechanick J.I., 2014. Carnitine deficiency in chronic critical illness. Current Opinion in Clinical Nutrition and Metabolic Care 17(2) pp. 200-209. [DOI] [Web of Science] [Pubmed]
Hazan R., Maura D., Que Y.A., Rahme L.G., 2014. Assessing Pseudomonas aeruginosa Persister/antibiotic tolerant cells. Methods in Molecular Biology 1149 pp. 699-707. [DOI] [Web of Science] [Pubmed]
Marguerettaz M., Dieppois G., Que Y.A., Ducret V., Zuchuat S., Perron K., 2014. Sputum containing zinc enhances carbapenem resistance, biofilm formation and virulence of Pseudomonas aeruginosa. Microbial Pathogenesis 77 pp. 36-41. [DOI] [Web of Science] [Pubmed]
Que Y.A., Lazar H., Wolff M., François B., Laterre P.F., Mercier E., Garbino J., Pagani J.L., Revelly J.P., Mus E. et al., 2014. Assessment of panobacumab as adjunctive immunotherapy for the treatment of nosocomial Pseudomonas aeruginosa pneumonia. European Journal of Clinical Microbiology and Infectious Diseases 33(10) pp. 1861-1867. [DOI] [Web of Science] [Pubmed]
Aymon L., Kissling S., Revelly J.P., Que Y.A., Schneider A.G., 2013. Epuration extrarénale continue pour l'insuffisance rénale aiguë aux soins intensifs [Continuous renal replacement therapy for acute kidney injury]. Revue Médicale Suisse 9(410) pp. 2324, 2326-2324, 2329. [Pubmed]
De Buys Roessingh A., Guerid S, Que Y.A., Berger M., Hirt-Burri N., Scaletta C., Wassim R., Applegate L.A., 2013. Cell Therapy Assistance in Reconstructive Surgery for Musculoskeletal Tissues Following Burn and Trauma: Swiss Cellular Transplantation Platform. Journal of Defense Management 1(S3) pp. 1-7. [Document] [DOI]
Jacquet J., Que Y.A., Berger M.M., 2013. Burn Trauma in the Elderly: treating those with a chance. pp. 887-894 in Vincent J.L. (eds.) Annual Update in Intensive Care and Emergency Medicine 2013. Springer, Berlin. [DOI]
Que Y.A., Hazan R., Strobel B., Maura D., He J., Kesarwani M., Panopoulos P., Tsurumi A., Giddey M., Wilhelmy J. et al., 2013. A quorum sensing small volatile molecule promotes antibiotic tolerance in bacteria. PLoS One 8(12) pp. e80140. [DOI] [Web of Science] [Pubmed]
Veloso T.R., Chaouch A., Roger T., Giddey M., Vouillamoz J., Majcherczyk P., Que Y.A., Rousson V., Moreillon P., Entenza J.M., 2013. Use of a human-like low-grade bacteremia model of experimental endocarditis to study the role of Staphylococcus aureus adhesins and platelet aggregation in early endocarditis. Infection and Immunity 81(3) pp. 697-703. [DOI] [Web of Science] [Pubmed]
Apidianakis Y., Que Y.A., Xu W., Tegos G.P., Zimniak P., Hamblin M.R., Tompkins R.G., Xiao W., Rahme L.G., 2012. Down-regulation of glutatione S-transferase α 4 (hGSTA4) in the muscle of thermally injured patients is indicative of susceptibility to bacterial infection. Faseb Journal 26(2) pp. 730-737. [DOI] [Pubmed]
Bandyopadhaya A., Kesarwani M., Que Y.A., He J., Padfield K., Tompkins R., Rahme L.G., 2012. The quorum sensing volatile molecule 2-amino acetophenon modulates host immune responses in a manner that promotes life with unwanted guests. Plos Pathogens 8(11) pp. e1003024. [DOI] [Web of Science] [Pubmed]
Hazan R., Que Y.A., Maura D., Rahme L.G., 2012. A method for high throughput determination of viable bacteria cell counts in 96-well plates. Bmc Microbiology 12(1) p. 259. [DOI] [Pubmed]
Que Y.A., Delodder F., Guessous I., Graf R., Bain M., Calandra T., Liaudet L., Eggimann P., 2012. Pancreatic stone protein as an early biomarker predicting mortality in a prospective cohort of patients with sepsis requiring ICU management. Critical Care 16(4) pp. R114. [Document] [DOI] [Web of Science] [Pubmed]
Berger M.M., Que Y.A., 2011. Bioinformatics assistance of metabolic and nutrition management in the ICU. Current Opinion in Clinical Nutrition and Metabolic Care 14(2) pp. 202-208. [DOI] [Web of Science] [Pubmed]
Jolivet P., Christen G., Seematter G., Que Y.A., Eggimann P., 2011. Utilité des biomarqueurs du sepsis en réanimation [Usefulness of biomarkers of sepsis in the ICU]. Revue Médicale Suisse 7(321) pp. 2430-2434. [Pubmed]
Kesarwani M., Hazan R., He J., Que YA., Apidianakis Y., Lesic B., Xiao G., Dekimpe V., Milot S., Deziel E. et al., 2011. A quorum sensing regulated small volatile molecule reduces acute virulence and promotes chronic infection phenotypes. Plos Pathogens 7(8) pp. e1002192. [DOI] [Web of Science] [Pubmed]
Lower S.K., Lamlertthon S., Casillas-Ituarte N.N., Lins R.D., Yongsunthon R., Taylor E.S., Dibartola A.C., Edmonson C., McIntyre L.M., Reller L.B. et al., 11-2011. Polymorphisms in fibronectin binding protein A of Staphylococcus aureus are associated with infection of cardiovascular devices. Proceedings of the National Academy of Sciences of the United States of America 108(45) pp. 18372-18377. [DOI] [Web of Science] [Pubmed]
Que Y.A., Hazan R., Ryan C.M., Milot S., Lépine F., Lydon M., Rahme L.G., 2011. Production of Pseudomonas aeruginosa Intercellular Small Signaling Molecules in Human Burn Wounds. Journal of Pathogens 2011(ID 549302) pp. 1-5. [Document] [DOI]
Que Y.A., Moreillon P., 2011. Infective endocarditis. Nature Reviews. Cardiology 8(6) pp. 322-336. [DOI] [Web of Science] [Pubmed]
Buck A.W., Fowler V.G., Yongsunthon R., Liu J., DiBartola A.C., Que Y.A., Moreillon P., Lower S.K., 2010. Bonds between fibronectin and fibronectin-binding proteins on Staphylococcus aureus and Lactococcus lactis. Langmuir 26(13) pp. 10764-10770. [DOI] [Web of Science] [Pubmed]
Delodder F., Liaudet L., Que Y.A., Lajaunias F., Graf R., Bain M., Moreillon P., Roger T., Calandra T., Eggimann P., 2010. Pancreatic stone protein (PSP): a biomarker of sepsis. in 50th International Conference on Antimicrobial Agents and Chemotherapy (ICAAC).
Que Y.A., Moreillon P., 2010. Staphylococcus aureus (Including Staphylococcal Toxic Shock). pp. 2543-2578 in Mandell G.L., Bennett J.E., Dolin R. (eds.) Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 7th ed, Churchill Livingstone Elsevier, Philadelphia.
Berger Mette M., Que Y.A., 2009. Traitement nutritionnel du grand brûlé [Nutritional therapy in major burns]. Réanimation 18(8) pp. 694-701. [DOI]
Heying R., van de Gevel J., Que Y.A., Piroth L., Moreillon P., Beekhuizen H., 2009. Contribution of (sub)domains of Staphylococcus aureus fibronectin-binding protein to the proinflammatory and procoagulant response of human vascular endothelial cells. Thrombosis and Haemostasis 101(3) pp. 495-504. [DOI] [Web of Science] [Pubmed]
Seravalli L., Pralong F., Revelly J.P., Que Y.A., Chollet M., Chioléro R., 2009. Fonction surrénalienne après bolus d'étomidate en chirurgie cardiaque: une étude rétrospective [Adrenal function after induction of cardiac surgery patients with etomidate: a retrospective study]. Annales françaises d'anesthèsie et de réanimation 28(9) pp. 743-747. [DOI] [Web of Science] [Pubmed]
Piroth L., Que Y.A., Widmer E., Panchaud A., Piu S., Entenza J.M., Moreillon P., 2008. The fibrinogen- and fibronectin-binding domains of Staphylococcus aureus fibronectin-binding protein A synergistically promote endothelial invasion and experimental endocarditis. Infection and Immunity 76(8) pp. 3824-3831. [DOI] [Web of Science] [Pubmed]
Heying R., van de Gevel J., Que Y.A., Moreillon P., Beekhuizen H., 2007. Fibronectin-binding proteins and clumping factor A in Staphylococcus aureus experimental endocarditis: FnBPA is sufficient to activate human endothelial cells. Thrombosis and haemostasis 97(4) pp. 617-26. [DOI] [Web of Science] [Pubmed]
Aellen S., Que Y.A., Guignard B., Haenni M., Moreillon P., 2006. Detection of live and antibiotic-killed bacteria by quantitative real-time PCR of specific fragments of rRNA. Antimicrobial Agents and Chemotherapy 50(6) pp. 1913-1920. [DOI] [Web of Science] [Pubmed]
Moreillon P., Bizzini A., Que Y. A., 2006. Infective endocarditis in the elderly. pp. 1749-1762 in Patty J.M.S., Sinclair A.J., Morley J.E. (eds.) Principles and Practice of Geriatric Medicine. 4th ed., John Wiley & Sons.
Que Y.A., Moreillon P., Francioli P., 2006. L'endocardite en pratique ambulatoire [Infective endocarditis and outpatient practice]. Revue Médicale Suisse 2(60) pp. 903-6, 908-11. [Pubmed]
Widmer E., Que Y.A., Entenza J.M., Moreillon P., 2006. New concepts in the pathophysiology of infective endocarditis. Current Infectious Disease Reports 8(4) pp. 271-279. [DOI] [Pubmed]
Moreillon P., Que Y. A., Glauser M. P., 2005. Staphylococcus aureus (Including Staphylococcal Toxic Shock). pp. 2321-2351 in Mandell G. L., Bennett J. E., Dolin R. (eds.) Mandell, Douglas and Bennett's Principles and Practice of Infectious Diseases. 6th ed, Churchill Livingstone, New York.
Que Y.A., Haefliger J.A., Piroth L., François P., Widmer E., Entenza J.M., Sinha B., Herrmann M., Francioli P., Vaudaux P. et al., 2005. Fibrinogen and fibronectin binding cooperate for valve infection and invasion in Staphylococcus aureus experimental endocarditis. Journal of Experimental Medicine 201(10) pp. 1627-1635. [DOI] [Web of Science] [Pubmed]
Moreillon P, Que YA, Glauser MP, 2004. Chapter 192 : Staphylococcus aureus (including toxic shock syndrome). pp. Chapter 192 in Mandell GL, Bennett JE, Dolin R (eds.) Principles and practice of infectious diseases. Churchill Linvingston Elsevier.
Moreillon P., Que Y.A., 2004. Infective endocarditis. Lancet 363(9403) pp. 139-149. [DOI] [Web of Science] [Pubmed]
Que Y.A., Oddo M., Liaudet L., Moreillon P., 2004. Endocardite infectieuse: mise au point [Infective endocarditis: update]. Revue Médicale de la Suisse Romande 124(6) pp. 341-346. [Pubmed]
Moreillon P., Que Y.A., Bayer A.S., 2002. Pathogenesis of streptococcal and staphylococcal endocarditis. Infectious Disease Clinics of North America 16(2) pp. 297-318. [DOI] [Web of Science] [Pubmed]
Cottagnoud P., Entenza J.M., Cottagnoud M., Que Y.A., Moreillon P., Taüber M.G., 2001. Sub-inhibitory concentrations of vancomycin prevent quinolone-resistance in a penicillin-resistant isolate of Streptococcus pneumoniae. BMC Microbiology 1 p. 9. [Document] [Pubmed]
Que Y.A., François P., Haefliger J.A., Entenza J.M., Vaudaux P., Moreillon P., 2001. Reassessing the role of Staphylococcus aureus clumping factor and fibronectin-binding protein by expression in Lactococcus lactis. Infection and Immunity 69(10) pp. 6296-6302. [DOI] [Web of Science] [Pubmed]
Que Y.A., Haefliger J.A., Francioli P., Moreillon P., 2000. Expression of Staphylococcus aureus clumping factor A in Lactococcus lactis subsp. cremoris using a new shuttle vector. Infection and Immunity 68(6) pp. 3516-3522. [DOI] [Web of Science] [Pubmed]
Sinha B., Francois P., Que Y.A., Hussain M., Heilmann C., Moreillon P., Lew D., Krause K.H., Peters G., Herrmann M., 2000. Heterologously expressed Staphylococcus aureus fibronectin-binding proteins are sufficient for invasion of host cells. Infection and Immunity 68(12) pp. 6871-6878. [DOI] [Web of Science] [Pubmed]
Que Y.A., Entenza J.M., Francioli P., Moreillon P., 1998. The impact of penicillinase on cefamandole treatment and prophylaxis of experimental endocarditis due to methicillin-resistant Staphylococcus aureus. Journal of Infectious Diseases 177(1) pp. 146-154. [DOI] [Web of Science] [Pubmed]
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