Go to: content | top | bottom | search
You are hereUNIL > Department of Biochemistry > Research > Translational research > Publications > 2008/2009


Articles | Reviews | Book sections


  1. Agak GW, Bejon P, Fegan G, Gicheru N, Villard V, Kajava AV, Marsh K, Corradin G. Longitudinal analyses of immune responses to Plasmodium falciparum derived peptides corresponding to novel blood stage antigens in coastal Kenya. Vaccine 2008 26(16) p. 1963-1971.
  2. Allenbach C, Launois P, Mueller C, Tacchini-Cottier F. An essential role for transmembrane TNF in the resolution of the inflammatory lesion induced by Leishmania major infection. European Journal of Immunology 2008 38(3) p. 720-731.
  3. Ambit A, Fasel N, Coombs GH, Mottram JC. An essential role for the Leishmania major metacaspase in cell cycle progression. Cell death and differentiation 2008 15(1) p. 113-122.
  4. Apel A, Herr I, Schwarz H, Rodemann HP, Mayer A. Blocked autophagy sensitizes resistant carcinoma cells to radiation therapy. Cancer research 2008 68(5) p. 1485-1494.
  5. Audran R, Lurati-Ruiz F, Genton B, Blythman HE, Ofori-Anyinam O, Reymond C, Corradin G, Spertini F. The synthetic Plasmodium falciparum circumsporozoite peptide PfCS102 as a malaria vaccine candidate: a randomized controlled phase I trial. PloS one 2009 4(10) p. e7304.
  6. Avalos AM, Valdivia AD, Muñoz N, Herrera-Molina R, Tapia JC, Lavandero S, Chiong M, Burridge K, Schneider P, Quest AF, Leyton L. Neuronal Thy-1 induces astrocyte adhesion by engaging syndecan-4 in a cooperative interaction with alphavbeta3 integrin that activates PKCalpha and RhoA. Journal of Cell Science 2009 122(Pt 19) p. 3462-3471.
  7. Back J, Malchiodi EL, Cho S, Scarpellino L, Schneider P, Kerzic MC, Mariuzza RA, Held W. Distinct conformations of Ly49 natural killer cell receptors mediate MHC class I recognition in trans and cis. Immunity 2009 31(4) p. 598-608.
  8. Belnoue E, Pihlgren M, McGaha TL, Tougne C, Rochat AF, Bossen C, Schneider P, Huard B, Lambert PH, Siegrist CA. APRIL is critical for plasmablast survival in the bone marrow and poorly expressed by early life bone marrow stromal cells. Blood 2008 111(5) p. 2755-2764.
  9. Bessa J, Jegerlehner A, Hinton HJ, Pumpens P, Saudan P, Schneider P, Bachmann MF. Alveolar macrophages and lung dendritic cells sense RNA and drive mucosal IgA responses. Journal of immunology 2009 183(6) p. 3788-99.
  10. Bongfen SE, Balam S, Torgler R, Romero JF, Corradin G. Processing of the circumsporozoite protein in infected hepatocytes is not dependent on aspartic proteases. Parasite Immunology 2008 30(6-7) p. 375-378.
  11. Bongfen SE, Ntsama PM, Offner S, Smith T, Felger I, Tanner M, Alonso P, Nebie I, Romero JF, Silvie O, Torgler R, Corradin G. The N-terminal domain of Plasmodium falciparum circumsporozoite protein represents a target of protective immunity. Vaccine 2009 27(2) p. 328-335.
  12. Bossen C, Cachero TG, Tardivel A, Ingold K, Willen L, Dobles M, Scott ML, Maquelin A, Belnoue E, Siegrist CA, Chevrier S, Acha-Orbea H, Leung H, Mackay F, Tschopp J, Schneider P. TACI, unlike BAFF-R, is solely activated by oligomeric BAFF and APRIL to support survival of activated B cells and plasmablasts. Blood 2008 111(3) p. 1004-1012.
  13. Bourreau E, Ronet C, Darcissac E, Lise MC, Sainte Marie D, Clity E, Tacchini-Cottier F, Couppie P, Launois P. Intralesional regulatory T-cell suppressive function during human acute and chronic cutaneous leishmaniasis due to Leishmania guyanensis. Infection and immunity 2009 77(4) p. 1465-1474.
  14. Bourreau E, Ronet C, Darsissac E, Lise MC, Marie DS, Clity E, Tacchini-Cottier F, Couppie P, Launois P. In leishmaniasis due to Leishmania guyanensis infection, distinct intralesional interleukin-10 and Foxp3 mRNA expression are associated with unresponsiveness to treatment. The Journal of infectious diseases 2009 199(4) p. 576-579.
  15. Brenner D, Brechmann M, Röhling S, Tapernoux M, Mock T, Winter D, Lehmann WD, Kiefer F, Thome M, Krammer PH, Arnold R. Phosphorylation of CARMA1 by HPK1 is critical for NF-kappaB activation in T cells. Proceedings of the National Academy of Sciences of the United States of America 2009 106(34) p. 14508-14513.
  16. Britschgi MR, Link A, Lissandrin TK, Luther SA. Dynamic modulation of CCR7 expression and function on naive T lymphocytes in vivo. Journal of Immunology 2008 181(11) p. 7681-7688.
  17. Chakour R, Allenbach C, Desgranges F, Charmoy M, Mauel J, Garcia I, Launois P, Louis J, Tacchini-Cottier F. A new function of the Fas-FasL pathway in macrophage activation. Journal of leukocyte biology 2009 86(1) p. 81-90.
  18. Chevrier S, Genton C, Kallies A, Karnowski A, Otten LA, Malissen B, Malissen M, Botto M, Corcoran LM, Nutt SL, Acha-Orbea H. CD93 is required for maintenance of antibody secretion and persistence of plasma cells in the bone marrow niche. Proceedings of the National Academy of Sciences of the United States of America 2009 106(10) p. 3895-3900
  19. Cirstoiu-Hapca A, Buchegger F, Bossy L, Kosinski M, Gurny R, Delie F. Nanomedicines for active targeting: physico-chemical characterization of paclitaxel-loaded anti-HER2 immuno¬nanoparticles and in vitro functional studies on target cells. European Journal of Pharmaceutical Sciences 2009 38(3) p. 230-237.
  20. Cuenin S, Tinel A, Janssens S, Tschopp J. p53-induced protein with a death domain (PIDD) isoforms differentially activate nuclear factor-kappaB and caspase-2 in response to genotoxic stress. Oncogene 2008 27(3) p. 387-396.
  21. Delaloye J, Roger T, Steiner-Tardivel QG, Le Roy D, Knaup Reymond M, Akira S, Petrilli V, Gomez CE, Perdiguero B, Tschopp J, Pantaleo G, Esteban M, Calandra T. Innate immune sensing of modified vaccinia virus Ankara (MVA) is mediated by TLR2-TLR6, MDA-5 and the NALP3 inflammasome. PLoS Pathogens 2009 5(6) p. e1000480.
  22. Dostert C, Guarda G, Romero JF, Menu P, Gross O, Tardivel A, Suva ML, Stehle JC, Kopf M, Stamenkovic I, Corradin G, Tschopp J. Malarial hemozoin is a Nalp3 inflammasome activating danger signal. PloS one 2009 4(8) p. e6510.
  23. Dostert C, Petrilli V, Van BR, Steele C, Mossman BT, Tschopp J. Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science 2008 320(5876) p. 674-677.
  24. Dotto GP. Crosstalk of Notch with p53 and p63 in cancer growth control. Nature reviews Cancer 2009 9(8) p. 587-595.
  25. Ermolaeva MA, Michallet MC, Papadopoulou N, Utermöhlen O, Kranidioti K, Kollias G, Tschopp J, Pasparakis M. Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses. Nature Immunology 2008 9(9) p. 1037-1046.
  26. Farley SM, Purdy DE, Ryabinina OP, Schneider P, Magun BE, Iordanov MS. Fas ligand-induced proinflammatory transcriptional responses in reconstructed human epidermis. Recruitment of the epidermal growth factor receptor and activation of MAP kinases. Journal of Biological Chemistry 2008 283(2) p. 919-928.
  27. Fiorini E, Ferrero I, Merck E, Favre S, Pierres M, Luther SA, MacDonald HR. Cutting edge: thymic crosstalk regulates delta-like 4 expression on cortical epithelial cells. Journal of Immunology 2008 181(12) p. 8199-8203.
  28. Fiorini E, Merck E, Wilson A, Ferrero I, Jiang W, Koch U, Auderset F, Laurenti E, Tacchini-Cottier F, Pierres M, Radtke F, Luther SA, Macdonald HR. Dynamic regulation of notch 1 and notch 2 surface expression during T cell development and activation revealed by novel monoclonal antibodies. Journal of immunology 2009 183(11) p. 7212-7222.
  29. Flueck C, Frank G, Smith T, Jafarshad A, Nebie I, Sirima SB, Olugbile S, Alonso P, Tanner M, Druilhe P, Felger I, Corradin G. Evaluation of two long synthetic merozoite surface protein 2 peptides as malaria vaccine candidates. Vaccine 2009 27(20) p. 2653-2661.
  30. Galluzzi L, Aaronson SA, Abrams J, Alnemri ES, Andrews DW, Baehrecke EH, Bazan NG, Blagosklonny MV, Blomgren K, Borner C, Bredesen DE, Brenner C, Castedo M, Cidlowski JA, Ciechanover A, Cohen GM, De Laurenzi V, De Maria R, Deshmukh M, Dynlacht BD, El-Deiry WS, Flavell RA, Fulda S, Garrido C, Golstein P, Gougeon ML, Green DR, Gronemeyer H, Hajnóczky G, Hardwick JM, Hengartner MO, Ichijo H, Jäättelä M, Kepp O, Kimchi A, Klionsky DJ, Knight RA, Kornbluth S, Kumar S, Levine B, Lipton SA, Lugli E, Madeo F, Malomi W, Marine JC, Martin SJ, Medema JP, Mehlen P, Melino G, Moll UM, Morselli E, Nagata S, Nicholson DW, Nicotera P, Nuñez G, Oren M, Penninger J, Pervaiz S, Peter ME, Piacentini M, Prehn JH, Puthalakath H, Rabinovich GA, Rizzuto R, Rodrigues CM, Rubinsztein DC, Rudel T, Scorrano L, Simon HU, Steller H, Tschopp J, Tsujimoto Y, Vandenabeele P, Vitale I, Vousden KH, Youle RJ, Yuan J, Zhivotovsky B, Kroemer G. Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes. Cell death and differentiation 2009 16(8) p. 1093-1107.
  31. Gari K, Constantinou A. The role of the Fanconi anemia network in the response to DNA replication stress. Critical reviews in biochemistry and molecular biology 2009 44(5) p. 292-325.
  32. Gari K, Decaillet C, Delannoy M, Wu L, Constantinou A. Remodeling of DNA replication structures by the branch point translocase FANCM. Proceedings of the National Academy of Sciences of the United States of America 2008 105(42) p. 16107-16112.
  33. Gari K, Décaillet C, Stasiak AZ, Stasiak A, Constantinou A. The Fanconi anemia protein FANCM can promote branch migration of Holliday junctions and replication forks. Molecular cell 2008 29(1) p. 141-148.
  34. Gasse P, Riteau N, Charron S, Girre S, Fick L, Pétrilli V, Tschopp J, Lagente V, Quesniaux VF, Ryffel B, Couillin I. Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis. American journal of respiratory and critical care medicine 2009 179(10) p. 903-913.
  35. Germain C, Campigna E, Salhi I, Morisseau S, Navarro-Teulon I, Mach JP, Pèlegrin A, Robert B. Redirecting NK cells mediated tumor cell lysis by a new recombinant bifunctional protein. Protein engineering, design and selection 2008 21(11) p. 665-672.
  36. Ghiringhelli F, Apetoh L, Tesniere A, Aymeric L, Ma Y, Ortiz C, Vermaelen K, Panaretakis T, Mignot G, Ullrich E, Perfettini JL, Schlemmer F, Tasdemir E, Uhl M, Génin P, Civas A, Ryffel B, Kanellopoulos J, Tschopp J, André F, Lidereau R, McLaughlin NM, Haynes NM, Smyth MJ, Kroemer G, Zitvogel L. Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors. Nature Medicine 2009 15(10) p. 1170-1178.
  37. Gondeau C, Corradin G, Heitz F, Le Peuch C, Balbo A, Schuck P, Kajava AV. The C-terminal domain of Plasmodium falciparum merozoite surface protein 3 self-assembles into alpha-helical coiled coil tetramer. Molecular and biochemical parasitology 2009 165(2) p. 153-161.
  38. Gross O, Poeck H, Bscheider M, Dostert C, Hannesschläger N, Endres S, Hartmann G, Tardivel A, Schweighoffer E, Tybulewicz V, Mocsai A, Tschopp J, Ruland J. Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence. Nature 2009 459(7245) p. 433-436.
  39. Guarda G, Dostert C, Staehli F, Cabalzar K, Castillo R, Tardivel A, Schneider P, Tschopp J. T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes. Nature 2009 460(7252) p. 269-273.
  40. Hailfinger S, Lenz G, Ngo V, Posvitz-Fejfar A, Rebeaud F, Guzzardi M, Penas EM, Dierlamm J, Chan WC, Staudt LM, Thome M. Essential role of MALT1 protease activity in activated B cell-like diffuse large B-cell lymphoma. Proceedings of the National Academy of Sciences of the United States of America 2009 106, p. 19946-19951.
  41. Hermosilla T, Muñoz D, Herrera-Molina R, Valdivia A, Muñoz N, Nham SU, Schneider P, Burridge K, Quest AF, Leyton L. Direct Thy-1/alphaVbeta3 integrin interaction mediates neuron to astrocyte communication. Biochimica et Biophysica Acta 2008 1783(6) p. 1111-1120.
  42. Hothorn M, Neumann H, Lenherr ED, Wehner M, Rybin V, Hassa PO, Uttenweiler A, Reinhardt M, Schmidt A, Seiler J, Ladurner AG, Herrmann C, Scheffzek K, Mayer A. Catalytic core of a membrane-associated eukaryotic polyphosphate polymerase. Science 2009 324(5926) p. 513-516.
  43. Howe J, Garidel P, Roessle M, Richter W, Alexander C, Fournier K, Mach JP, Waelli T, Gorczynski RM, Ulmer AJ, Zähringer U, Hartmann A, Rietschel ET, Brandenburg K. Structural investigations into the interaction of hemoglobin and part structures with bacterial endotoxins. Innate immunity 2008 14(1) p. 39-49.
  44. Howe J, Richter W, Hawkins L, Rössle M, Alexander C, Fournier K, Mach JP, Waelli T, Gorczynski RM, Ulmer AJ, Brade H, Zamyatina A, Kosma P, Rietschel ET, Brandenburg K. Hemoglobin enhances the biological activity of synthetic and natural bacterial (endotoxic) virulence factors: a general principle. Medicinal chemistry 2008 4(6) p. 520-525.
  45. Huard B, McKee T, Bosshard C, Durual S, Matthes T, Myit S, Donze O, Frossard C, Chizzolini C, Favre C, Zubler R, Guyot JP, Schneider P, Roosnek E. APRIL secreted by neutrophils binds to heparan sulfate proteoglycans to create plasma cell niches in human mucosa. Journal of Clinical Investigation 2008 118(8) p. 2887-2895.
  46. Imamura M, Tsutsui H, Yasuda K, Uchiyama R, Yumikura-Futatsugi S, Mitani K, Hayashi S, Akira S, Taniguchi S, Van Rooijen N, Tschopp J, Yamamoto T, Fujimoto J, Nakanishi K. Contribution of TIR domain-containing adapter inducing IFN-beta-mediated IL-18 release to LPS-induced liver injury in mice. Journal of hepatology 2009 51(2) p. 333-341.
  47. Kassahn D, Nachbur U, Conus S, Micheau O, Schneider P, Simon HU, Brunner T. Distinct requirements for activation-induced cell surface expression of preformed Fas/CD95 ligand and cytolytic granule markers in T cells. Cell Death and Differentiation 2009 16(1) p. 115-124.
  48. Kerth A, Garidel P, Howe J, Alexander C, Mach JP, Waelli T, Blume A, Th Rietschel E, Brandenburg K. An infrared reflection-absorption spectroscopic (IRRAS) study of the interaction of lipid A and lipopolysaccharide Re with endotoxin-binding proteins. Medicinal chemistry 2009 5(6) p. 535-5342.
  49. Khatri I, Alexander C, Brandenburg K, Fournier K, Lee L, Mach JP, Rietschel ET, Ulmer AJ, Waelli T, Gorczynski RM. A role for altered TLR gene expression in association with increased expression of CD200R in the induction of mucosal tissue CD4(+) Treg in aged mice following gavage with a liver extract along with intramuscular monophosphoryl lipid A (MPLA) injection. Experimental gerontology 2008 43(8) p. 771-781.
  50. Khatri I, Alexander C, Brandenburg K, Fournier K, Mach JP, Rietschel ET, Ulmer AJ, Terzioglu E, Waelli T, Gorczynski RM. Induction of tolerogenic vs immunogenic dendritic cells (DCs) in the presence of GM-CSF is regulated by the strength of signaling from monophosphoryl lipid A (MPLA) in association with glutathione and fetal hemoglobin gamma-chain. Immunology letters 2009 124(1) p. 44-49.
  51. Kolev V, Mandinova A, Guinea-Viniegra J, Hu B, Lefort K, Lambertini C, Neel V, Dummer R, Wagner EF, Dotto GP. EGFR signalling as a negative regulator of Notch1 gene transcription and function in proliferating keratinocytes and cancer. Nature cell biology 2008 10(8) p. 902-911.
  52. Kool M, Pétrilli V, De Smedt T, Rolaz A, Hammad H, van Nimwegen M, Bergen IM, Castillo R, Lambrecht BN, Tschopp J. Cutting edge: alum adjuvant stimulates inflammatory dendritic cells through activation of the NALP3 inflammasome. Journal of Immunology 2008 181(6) p. 3755-3759.
  53. Kulangara C, Kajava AV, Corradin G, Felger I. Sequence conservation in Plasmodium falciparum alpha-helical coiled coil domains proposed for vaccine development. PloS one 2009 4(5) p. e5419.
  54. Mandinova A, Lefort K, Tommasi di Vignano A, Stonely W, Ostano P, Chiorino G, Iwaki H, Nakanishi J, Dotto GP. The FoxO3a gene is a key negative target of canonical Notch signalling in the keratinocyte UVB response. EMBO journal 2008 27(8) p. 1243-1254.
  55. Manzl C, Krumschnabel G, Bock F, Sohm B, Labi V, Baumgartner F, Logette E, Tschopp J, Villunger A. Caspase-2 activation in the absence of PIDDosome formation. The Journal of cell biology 2009 185(2) p. 291-303.
  56. Massacand JC, Kaiser P, Ernst B, Tardivel A, Bürki K, Schneider P, Harris NL. Intestinal bacteria condition dendritic cells to promote IgA production. PLoS ONE 2008 3(7) p. e2588.
  57. Mauldin EA, Gaide O, Schneider P, Casal ML. Neonatal treatment with recombinant ectodysplasin prevents respiratory disease in dogs with X-linked ectodermal dysplasia. American Journal of Medical Genetics. Part A 2009 149A(9) p. 2045-2049.
  58. Mayer A. Cell-free reconstitution of microautophagy in yeast. Methods in enzymology 2008 451 p. 151-162.
  59. McFarlane E, Perez C, Charmoy M, Allenbach C, Carter KC, Alexander J, Tacchini-Cottier F. Neutrophils contribute to development of a protective immune response during onset of infection with Leishmania donovani. Infection and immunity 2008 76(2) p. 532-541.
  60. Meylan E, Tschopp J. NLRX1: friend or foe? EMBO Reports 2008 9(3) p. 243-245.
  61. Michallet MC, Meylan E, Ermolaeva MA, Vazquez J, Rebsamen M, Curran J, Poeck H, Bscheider M, Hartmann G, Konig M, Kalinke U, Pasparakis M, Tschopp J. TRADD protein is an essential component of the RIG-like helicase antiviral pathway. Immunity 2008 28(5) p. 651-661.
  62. Muruve DA, Pétrilli V, Zaiss AK, White LR, Clark SA, Ross PJ, Parks RJ, Tschopp J. The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response. Nature 2008 452(7183) p. 103-107.
  63. Narasimamurthy R, Geuking P, Ingold K, Willen L, Schneider P, Basler K. Structure-function analysis of Eiger, the Drosophila TNF homolog. Cell Research 2009 19(3) p. 392-394.
  64. Nebie I, Tiono AB, Diallo DA, Samandoulougou S, Diarra A, Konate AT, Cuzin-Ouattara N, Theisen M, Corradin G, Cousens S, Ouattara AS, Ilboudo-Sanogo E, Sirima BS. Do antibody responses to malaria vaccine candidates influenced by the level of malaria transmission protect from malaria? Tropical medicine & international health 2008 13(2) p. 229-237.
  65. Olugbile S, Kulangara C, Bang G, Bertholet S, Suzarte E, Villard V, Frank G, Audran R, Razaname A, Nebie I, Awobusuyi O, Spertini F, Kajava AV, Felger I, Druilhe P, Corradin G. Vaccine potentials of an intrinsically unstructured fragment derived from the blood stage-associated Plasmodium falciparum protein PFF0165c. Infection and immunity 2009 77(12) p. 5701-5709.
  66. Pappu BP, Borodovsky A, Zheng TS, Yang X, Wu P, Dong X, Weng S, Browning B, Scott ML, Ma L, Su L, Tian Q, Schneider P, Flavell RA, Dong C, Burkly LC. TL1A-DR3 interaction regulates Th17 cell function and Th17-mediated autoimmune disease. Journal of Experimental Medicine 2008 205(5) p. 1049-1062.
  67. Pedraza-Alva G, Zingg JM, Donda A, Pérez-Martínez L. Estrogen receptor regulates MyoD gene expression by preventing AP-1-mediated repression. Biochemical and Biophysical Research Communications 2009 389(2) p. 360-365.
  68. Perlaza BL, Valencia AZ, Zapata C, Castellanos A, Sauzet JP, Blanc C, Cohen J, Arévalo-Herrera M, Corradin G, Herrera S, Druilhe P. Protection against Plasmodium falciparum challenge induced in Aotus monkeys by liver-stage antigen-3-derived long synthetic peptides. European Journal of Immunology 2008 38(9) p. 2610-2615.
  69. Pradervand S, Weber J, Thomas J, Bueno M, Wirapati P, Lefort K, Dotto GP, Harshman K. Impact of normalization on miRNA microarray expression profiling. RNA 2009 15(3) p. 493-501.
  70. Rebeaud F, Hailfinger S, Posevitz-Fejfar A, Tapernoux M, Moser R, Rueda D, Gaide O, Guzzardi M, Iancu EM, Rufer N, Fasel N, Thome M. The proteolytic activity of the paracaspase MALT1 is key in T cell activation. Nature Immunology 2008 9(3) p. 272-281.
  71. Rebsamen M, Heinz LX, Meylan E, Michallet MC, Schroder K, Hofmann K, Vazquez J, Benedict CA, Tschopp J. DAI/ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF-kappaB. EMBO reports 2009 10(8) p. 916-922.
  72. Rebsamen M, Meylan E, Curran J, Tschopp J. The antiviral adaptor proteins Cardif and Trif are processed and inactivated by caspases. Cell Death and Differentiation 2008 15(11) p. 1804-1811.
  73. Romero JF, Ciabattini A, Guillaume P, Frank G, Ruggiero P, Pettini E, Del Giudice G, Medaglini D, Corradin G. Intranasal administration of the synthetic polypeptide from the C-terminus of the circumsporozoite protein of Plasmodium berghei with the modified heat-labile toxin of Escherichia coli (LTK63) induces a complete protection against malaria challenge. Vaccine 2009 27(8) p. 1266-1271.
  74. Ronet C, Voigt H, Himmelrich H, Doucey MA, Hauyon-La Torre Y, Revaz-Breton M, Tacchini-Cottier F, Bron C, Louis J, Launois P. Leishmania major-specific B cells are necessary for Th2 cell development and susceptibility to L. major LV39 in BALB/c mice. Journal of Immunology 2008 180(7) p. 4825-4835.
  75. Roques C, Coulombe Y, Delannoy M, Vignard J, Grossi S, Brodeur I, Rodrigue A, Gautier J, Stasiak AZ, Stasiak A, Constantinou A, Masson JY. MRE11-RAD50-NBS1 is a critical regulator of FANCD2 stability and function during DNA double-strand break repair. The EMBO journal 2009 28(16) p. 2400-2413.
  76. Salzer U, Bacchelli C, Buckridge S, Pan-Hammarström Q, Jennings S, Lougaris V, Bergbreiter A, Hagena T, Birmelin J, Plebani A, Webster AD, Peter HH, Suez D, Chapel H, McLean-Tooke A, Spickett GP, Anover-Sombke S, Ochs HD, Urschel S, Belohradsky BH, Ugrinovic S, Kumararatne DS, Lawrence TC, Holm AM, Franco JL, Schulze I, Schneider P, Gertz EM, Schäffer AA, Hammarström L, Thrasher AJ, Gaspar HB, Grimbacher B. Relevance of biallelic versus monoallelic TNFRSF13B mutations in distinguishing disease-causing from risk-increasing TNFRSF13B variants in antibody deficiency syndromes. Blood 2009 113(9) p. 1967-1976.
  77. Scandella E, Bolinger B, Lattmann E, Miller S, Favre S, Littman DR, Finke D, Luther SA, Junt T, Ludewig B. Restoration of lymphoid organ integrity through the interaction of lymphoid tissue-inducer cells with stroma of the T cell zone. Nature immunology 2008 9(6) p. 667-675.
  78. Schmutz S, Bosco N, Chappaz S, Boyman O, Acha-Orbea H, Ceredig R, Rolink AG, Finke D. Cutting edge: IL-7 regulates the peripheral pool of adult ROR gamma+ lymphoid tissue inducer cells. Journal of immunology 2009 183(4) p. 2217-2221.
  79. Schuler P, Contassot E, Irla M, Hugues S, Preynat-Seauve O, Beermann F, Donda A, French LE, Huard B. Direct presentation of a melanocyte-associated antigen in peripheral lymph nodes induces cytotoxic CD8+ T cells. Cancer research 2008 68(20) p. 8410-8418.
  80. Schroder K, Muruve DA, Tschopp J. Innate immunity: cytoplasmic DNA sensing by the AIM2 inflammasome. Current biology 2009 19(6) p. R262-R265.
  81. Sharma SK, Goloubinoff P, Christen P. Heavy metal ions are potent inhibitors of protein folding. Biochemical and Biophysical Research Communications 2008 372(2) p. 341-345.
  82. Sharp FA, Ruane D, Claass B, Creagh E, Harris J, Malyala P, Singh M, O'Hagan DT, Pétrilli V, Tschopp J, O'Neill LA, Lavelle E.C. Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome. Proceedings of the National Academy of Sciences of the United States of America 2009 106(3) p. 870-875.
  83. Steiner Q.G, Otten LA, Hicks MJ, Kaya G, Grosjean F, Saeuberli E, Lavanchy C, Beermann F, McClain KL, Acha-Orbea H. In vivo transformation of mouse conventional CD8alpha+ dendritic cells leads to progressive multisystem histiocytosis. Blood 2008 111(4) p. 2073-2082.
  84. Stirnemann K, Romero JF, Baldi L, Robert B, Cesson V, Besra GS, Zauderer M, Wurm F, Corradin G, Mach JP, Macdonald HR, Donda A. Sustained activation and tumor targeting of NKT cells using a CD1d-anti-HER2-scFv fusion protein induce antitumor effects in mice. Journal of Clinical Investigation 2008 118(3) p. 994-1005.
  85. Swee LK, Ingold-Salamin K, Tardivel A, Willen L, Gaide O, Favre M, Demotz S, Mikkola M, Schneider P. Biological activity of ectodysplasin A is conditioned by its collagen and heparan sulfate proteoglycan-binding domains. The Journal of biological chemistry 2009 284(40) p. 27567-27576.
  86. Thurau M, Marquardt G, Gonin-Laurent N, Weinländer K, Naschberger E, Jochmann R, Alkharsah KR, Schulz TF, Thome M, Neipel F, Stürzl M. Viral inhibitor of apoptosis vFLIP/K13 protects endothelial cells against superoxide-induced cell death. Journal of virology 2009 83(2) p. 598-611.
  87. Tomei AA, Siegert S, Britschgi MR, Luther SA, Swartz MA. Fluid flow regulates stromal cell organization and CCL21 expression in a tissue-engineered lymph node microenvironment. Journal of Immunology 2009 183(7) p. 4273-4283.
  88. Torgler R, Bongfen SE, Romero JC, Tardivel A, Thome M, Corradin G. Sporozoite-mediated hepatocyte wounding limits Plasmodium parasite development via MyD88-mediated NF-kappa B activation and inducible NO synthase expression. Journal of Immunology 2008 180(6) p. 3990-3999.
  89. Toure-Balde A, Perlaza BL, Sauzet JP, Ndiaye M, Aribot G, Tall A, Sokhna C, Rogier C, Corradin G, Roussilhon C, Druilhe P. Evidence for multiple B- and T-cell epitopes in Plasmodium falciparum liver-stage antigen 3. Infection and immunity 2009 77(3) p. 1189-1196.
  90. Tu W, Lau YL, Zheng J, Liu Y, Chan PL, Mao H, Dionis K, Schneider P, Lewis DB. Efficient generation of human alloantigen-specific CD4+ regulatory T cells from naive precursors by CD40-activated B cells. Blood 2008 112(6) p. 2554-62.
  91. Uttenweiler A, Mayer A. Microautophagy in the yeast Saccharomyces cerevisiae. Methods in Molecular Biology 2008 445 p. 245-259.
  92. Verdini A, Terenzi S, Brossard V, Roggero M, Corradin G. Oxidative folding of synthetic polypeptides S-protected as tert-butylthio derivatives. Journal of Peptide Science 2008 14(12) p. 1271-1282.
  93. Vince JE, Chau D, Callus B, Wong WW, Hawkins CJ, Schneider P, McKinlay M, Benetatos CA, Condon SM, Chunduru SK, Yeoh G, Brink R, Vaux DL, Silke J. TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFalpha. The Journal of cell biology 2008 182(1) p. 171-84.
  94. Vince JE, Chau D, Callus B, Wong WW, Hawkins CJ, Schneider P, McKinlay M, Benetatos CA, Condon SM, Chunduru SK, Yeoh G, Brink R, Vaux DL, Silke J. TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFalpha. Journal of Cell Biology 2008 182(1) p. 171-184.
  95. Voelter V, Rufer N, Reynard S, Greub G, Brookes R, Guillaume P, Grosjean F, Fagerberg T, Michielin O, Rowland-Jones S, Pinilla C, Leyvraz S, Romero P, Appay V. Characterization of Melan-A reactive memory CD8+ T cells in a healthy donor. International Immunology 2008 20(8) p. 1087-1096.
  96. Vogt TK, Link A, Perrin J, Finke D, Luther SA. Novel function for interleukin-7 in dendritic cell development. Blood 2009 113(17) p. 3961-3968
  97. Wang Y, Kissenpfennig A, Mingueneau M, Richelme S, Perrin P, Chevrier S, Genton C, Lucas B, DiSanto JP, Acha-Orbea H, Malissen B, Malissen M. Th2 lymphoproliferative disorder of LatY136F mutant mice unfolds independently of TCR-MHC engagement and is insensitive to the action of Foxp3+ regulatory T cells. Journal of Immunology 2008 180(3) p. 1565-1575.
  98. Watanabe H, Gehrke S, Contassot E, Roques S, Tschopp J, Friedmann PS, French LE, Gaide O. Danger signaling through the inflammasome acts as a master switch between tolerance and sensitization. Journal of Immunology 2008 180(9) p. 5826-5832.
  99. Willett BJ, McMonagle EL, Logan N, Schneider P, Hosie MJ. Enforced covalent trimerisation of soluble feline CD134 (OX40)-ligand generates a functional antagonist of feline immunodeficiency virus. Molecular Immunology 2009 46(6) p. 1020-1030.
  100. Ychou M, Azria D, Menkarios C, Faurous P, Quenet F, Saint-Aubert B, Rouanet P, Pèlegrin M, Bascoul-Mollevi C, Guerreau D, Saccavini JC, Mach JP, Artus JC, Pèlegrin A. Adjuvant radioimmunotherapy trial with iodine-131-labeled anti-carcinoembryonic antigen monoclonal antibody F6 F(ab')2 after resection of liver metastases from colorectal cancer. Clinical cancer research 2008 14(11) p. 3487-3493.
  101. Zaiss AK, Vilaysane A, Cotter MJ, Clark SA, Meijndert HC, Colarusso P, Yates RM, Petrilli V, Tschopp J, Muruve D.A. Antiviral antibodies target adenovirus to phagolysosomes and amplify the innate immune response. Journal of immunology 2009 182(11) p. 7058-7068.



  1. Bongfen SE, Ntsama PM, Offner S, Smith T, Felger I, Tanner M, Alonso P, Nebie I, Romero JF, Silvie O, Torgler R, Corradin G. 2009. The N-terminal domain of Plasmodium falciparum circumsporozoite protein represents a target of protective immunity. Vaccine 2009 27(2) p. 328-335.
  2. Dostert C, Meylan E, Tschopp J. Intracellular pattern-recognition receptors. Advanced Drug Delivery Reviews 2008 60(7) p. 830-840.
  3. Dotto GP. Notch tumor suppressor function. Oncogene 2008 27(38) p. 5115-5123.
  4. Hailfinger S, Rebeaud F, Thome M. Adapter and enzymatic functions of proteases in T-cell activation. Immunological reviews 2009 232(1) p. 334-347.
  5. Kroemer G, Galluzzi L, Vandenabeele P, Abrams J, Alnemri ES, Baehrecke EH, Blagosklonny MV, El-Deiry WS, Golstein P, Green DR, Hengartner M, Knight RA, Kumar S, Lipton SA, Malorni W, Nunez G, Peter ME, Tschopp J, Yuan J, Piacentini M, Zhivotovsky B, Melino G. Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009. Cell death and differentiation 2009 16(1) p. 3-11.
  6. Launois P, Tacchini-Cottier F, Kieny MP. Cutaneous leishmaniasis: progress towards a vaccine. Expert Review of Vaccines 2008 7(8) p. 1277-1287.
  7. Mackay F, Schneider P. TACI, an enigmatic BAFF/APRIL receptor, with new unappreciated biochemical and biological properties. Cytokine & Growth Factor Reviews 2008 19(3-4) p. 263-276
  8. Mackay F, Schneider P. Cracking the BAFF code. Nature reviews. Immunology 2009 9(7) p. 491-502.
  9. Martinon F, Mayor A, Tschopp J. The inflammasomes: guardians of the body. Annual review of immunology 2009 27 p. 229-265.
  10. Thome M. Multifunctional roles for MALT1 in T-cell activation. Nature Reviews Immunology 2008 8(7) p. 495-500.


Book sections

  1. Fasel N, Acestor N, El Fadili-Kündig A, Gonzalez I, Masina S. 2008. The Leishmania Proteome. pp.55-74 in Myler P.J. (eds.), Fasel N. (eds.), Leishmania : after the genome. chap. 4 Caister Academic Press.
  2. Guichard G, Trouche N, Wieckowski S, Sun W, Chaloin O, Bianco A, Hoebeke J, Schneider P, Fournel S. 2009. Rationally-designed multivalent architectures for mimicking homotrimers of CD40L, a member of the TNF superfamily. pp.355-357 in Del Valle S. (eds.), Escher E. (eds.), Lubell W.D. (eds.), Peptides for youth. Advances in experimental medicine and biology 611(7). chap. 7 Springer.
  3. Mackay F, Schneider P. 2009. Cracking the BAFF code. Nature reviews. Immunology 9(7) p. 491-502.
  4. Schneider P. 2008. Signaling by TNF and related ligands. pp.433-441 in Epstein C. (eds.), Erickson R. (eds.), Wynshaw-Boris A. (eds.), Inborn Errors of Development. 2nd edition, Oxford monographs on medical genetics 54. chap. 41 Oxford University Press.
  5. Tacchini-Cottier F, Launois P. 2008. Host responses to infections with Leishmania. pp.263-280 in Myler P.J. (eds.), Fasel N. (eds.), Leishmania : after the Genome. chap. 12 Caister Academic Press.


Chemin des Boveresses 155 - CH-1066 Epalinges  - Switzerland  -  Tel. +41 21 692 5700  -  Fax +41 21 692 5705
Swiss University