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Publications 2004/2005

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  • Agostini, L., Martinon, F., Burns, K., McDermott, M. F., Hawkins, P. N., and Tschopp, J. (2004). NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder. Immunity 20, 319-325.
  • Ahua, K. M., Ioset, J. R., Ransijn, A., Mauel, J., Mavi, S., and Hostettmann, K. (2004). Antileishmanial and antifungal acridone derivatives from the roots of Thamnosma rhodesica. Phytochemistry 65, 963-968.
  • Anderle, P., Rumbo, M., Sierro, F., Mansourian, R., Michetti, P., Roberts, M. A., and Kraehenbuhl, J. P. (2005). Novel markers of the human follicle-associated epithelium identified by genomic profiling and microdissection. Gastroenterology 129, 321-327.
  • Arinola, O. G., Louis, J., Tacchini-Cottier, F., Aseffa, A., and Salimonu, L. S. (2004). Interleukin-4 (IL-4) and interferon-gamma (IFN-gamma) in pregnant C57BL/6 mice infected with L. major at different gestational periods. West Afr J Med 23, 202-207.
  • Arinola, O. G., Louis, J. S., Tacchini-Cottier, F., Aseffa, A., and Salimonu, L. S. (2005). Pregnancy impairs resistance of C57BL/6 mice to Leishmania major infection. Afr J Med Med Sci 34, 65-70.
  • Audran, R., Cachat, M., Lurati, F., Soe, S., Leroy, O., Corradin, G., Druilhe, P., and Spertini, F. (2005). Phase I malaria vaccine trial with a long synthetic peptide derived from the merozoite surface protein 3 antigen. Infect Immun 73, 8017-8026.
  • Avalos, A. M., Arthur, W. T., Schneider, P., Quest, A. F., Burridge, K., and Leyton, L. (2004). Aggregation of integrins and RhoA activation are required for Thy-1-induced morphological changes in astrocytes. J Biol Chem 279, 39139-39145.
  • Ballou, W. R., Arevalo-Herrera, M., Carucci, D., Richie, T. L., Corradin, G., Diggs, C., Druilhe, P., Giersing, B. K., Saul, A., Heppner, D. G., Kester, K. E., Lanar, D. E., Lyon, J., Hill, A. V., Pan, W., and Cohen, J. D. (2004). Update on the clinical development of candidate malaria vaccines. Am J Trop Med Hyg 71, 239-247.
  • Barbey, C., Donatelli-Dufour, N., Batard, P., Corradin, G., and Spertini, F. (2004). Intranasal treatment with ovalbumin but not the major T cell epitope ovalbumin 323-339 generates interleukin-10 secreting T cells and results in the induction of allergen systemic tolerance. Clin Exp Allergy 34, 654-662.
  • Batten, M., Fletcher, C., Ng, L. G., Groom, J., Wheway, J., Laabi, Y., Xin, X., Schneider, P., Tschopp, J., Mackay, C. R., and Mackay, F. (2004). TNF deficiency fails to protect BAFF transgenic mice against autoimmunity and reveals a predisposition to B cell lymphoma. J Immunol 172, 812-822.
  • Bistrup, A., Tsay, D., Shenoy, P., Singer, M. S., Bangia, N., Luther, S. A., Cyster, J. G., Ruddle, N. H., and Rosen, S. D. (2004). Detection of a sulfotransferase (HEC-GlcNAc6ST) in high endothelial venules of lymph nodes and in high endothelial venule-like vessels within ectopic lymphoid aggregates: relationship to the MECA-79 epitope. Am J Pathol 164, 1635-1644.
  • Buchegger, F., Adamer, F., Schaffland, A. O., Kosinski, M., Grannavel, C., Dupertuis, Y. M., de Tribolet, N., Mach, J. P., and Delaloye, A. B. (2004). Highly efficient DNA incorporation of intratumourally injected [125I]iododeoxyuridine under thymidine synthesis blocking in human glioblastoma xenografts. Int J Cancer 110, 145-149.
  • Cebecauer, M., Guillaume, P., Hozak, P., Mark, S., Everett, H., Schneider, P., and Luescher, I. F. (2005). Soluble MHC-peptide complexes induce rapid death of CD8+ CTL. J Immunol 174, 6809-6819.
  • Chapatte, L., Servis, C., Valmori, D., Burlet-Schiltz, O., Dayer, J., Monsarrat, B., Romero, P., and Levy, F. (2004). Final antigenic Melan-A peptides produced directly by the proteasomes are preferentially selected for presentation by HLA-A*0201 in melanoma cells. J Immunol 173, 6033-6040.
  • Constantinou, A., and West, S. C. (2004). Holliday junction branch migration and resolution assays. Methods Mol Biol 262, 239-253.
  • Crettaz, D., Sensebe, L., Vu, D. H., Schneider, P., Depasse, F., Bienvenut, W. V., Quadroni, M., and Tissot, J. D. (2004). Proteomics of methylene blue photo-treated plasma before and after removal of the dye by an absorbent filter. Proteomics 4, 881-891.
  • Devgan, V., Mammucari, C., Millar, S. E., Brisken, C., and Dotto, G. P. (2005). p21WAF1/Cip1 is a negative transcriptional regulator of Wnt4 expression downstream of Notch1 activation. Genes Dev 19, 1485-1495.
  • Didierlaurent, A., Ferrero, I., Otten, L. A., Dubois, B., Reinhardt, M., Carlsen, H., Blomhoff, R., Akira, S., Kraehenbuhl, J. P., and Sirard, J. C. (2004). Flagellin promotes myeloid differentiation factor 88-dependent development of Th2-type response. J Immunol 172, 6922-6930.
  • Didierlaurent, A., Ramirez, J. C., Gherardi, M., Zimmerli, S. C., Graf, M., Acha-Orbea, A., Pantaleo, G., Wagner, R., Esteban, M., Kraehenbuhl, J. P., and Sirard, J. C. (2004). Attenuated poxviruses expressing a synthetic HIV protein stimulate HLA-A2-restricted cytotoxic T-cell responses. Vaccine 22, 3395-3403.
  • Dohrman, A., Kataoka, T., Cuenin, S., Russell, J. Q., Tschopp, J., and Budd, R. C. (2005). Cellular FLIP (long form) regulates CD8+ T cell activation through caspase-8-dependent NF-kappaB activation. J Immunol 174, 5270-5278.
  • Dohrman, A., Russell, J. Q., Cuenin, S., Fortner, K., Tschopp, J., and Budd, R. C. (2005). Cellular FLIP long form augments caspase activity and death of T cells through heterodimerization with and activation of caspase-8. J Immunol 175, 311-318.
  • Doucey, M. A., Scarpellino, L., Zimmer, J., Guillaume, P., Luescher, I. F., Bron, C., and Held, W. (2004). Cis association of Ly49A with MHC class I restricts natural killer cell inhibition. Nat Immunol 5, 328-336.
  • Druilhe, P., Spertini, F., Soesoe, D., Corradin, G., Mejia, P., Singh, S., Audran, R., Bouzidi, A., Oeuvray, C., and Roussilhon, C. (2005). A malaria vaccine that elicits in humans antibodies able to kill Plasmodium falciparum. PLoS Med 2, e344.
  • Germain, C., Larbouret, C., Cesson, V., Donda, A., Held, W., Mach, J. P., Pelegrin, A., and Robert, B. (2005). MHC class I-related chain a conjugated to antitumor antibodies can sensitize tumor cells to specific lysis by natural killer cells. Clin Cancer Res 11, 7516-7522.
  • Grill, B., Wilson, G. M., Zhang, K. X., Wang, B., Doyonnas, R., Quadroni, M., and Schrader, J. W. (2004). Activation/division of lymphocytes results in increased levels of cytoplasmic activation/proliferation-associated protein-1: prototype of a new family of proteins. J Immunol 172, 2389-2400.
  • Gross, A., Bertholet, S., Mauel, J., and Dornand, J. (2004). Impairment of Brucella growth in human macrophagic cells that produce nitric oxide. Microb Pathog 36, 75-82.
  • Grossi, M., Hiou-Feige, A., Di Vignano, A. T., Calautti, E., Ostano, P., Lee, S., Chiorino, G., and Dotto, G. P. (2005). Negative control of keratinocyte differentiation by Rho/CRIK signaling coupled with up-regulation of KyoT1/2 (FHL1) expression. Proc Natl Acad Sci U S A 102, 11313-11318.
  • Guler, R., Olleros, M. L., Vesin, D., Parapanov, R., Vesin, C., Kantengwa, S., Rubbia-Brandt, L., Mensi, N., Angelillo-Scherrer, A., Martinez-Soria, E., Tacchini-Cottier, F., and Garcia, I. (2004). Inhibition of inducible nitric oxide synthase protects against liver injury induced by mycobacterial infection and endotoxins. J Hepatol 41, 773-781.
  • Herrera, S., Bonelo, A., Perlaza, B. L., Fernandez, O. L., Victoria, L., Lenis, A. M., Soto, L., Hurtado, H., Acuna, L. M., Velez, J. D., Palacios, R., Chen-Mok, M., Corradin, G., and Arevalo-Herrera, M. (2005). Safety and elicitation of humoral and cellular responses in colombian malaria-naive volunteers by a Plasmodium vivax circumsporozoite protein-derived synthetic vaccine. Am J Trop Med Hyg 73, 3-9.
  • Herrera, S., Bonelo, A., Perlaza, B. L., Valencia, A. Z., Cifuentes, C., Hurtado, S., Quintero, G., Lopez, J. A., Corradin, G., and Arevalo-Herrera, M. (2004). Use of long synthetic peptides to study the antigenicity and immunogenicity of the Plasmodium vivax circumsporozoite protein. Int J Parasitol 34, 1535-1546.
  • Huard, B., Arlettaz, L., Ambrose, C., Kindler, V., Mauri, D., Roosnek, E., Tschopp, J., Schneider, P., and French, L. E. (2004). BAFF production by antigen-presenting cells provides T cell co-stimulation. Int Immunol 16, 467-475.
  • Ingold, K., Zumsteg, A., Tardivel, A., Huard, B., Steiner, Q. G., Cachero, T. G., Qiang, F., Gorelik, L., Kalled, S. L., Acha-Orbea, H., Rennert, P. D., Tschopp, J., and Schneider, P. (2005). Identification of proteoglycans as the APRIL-specific binding partners. J Exp Med 201, 1375-1383.
  • Iordanov, M. S., Ryabinina, O. P., Schneider, P., and Magun, B. E. (2005). Two mechanisms of caspase 9 processing in double-stranded RNA- and virus-triggered apoptosis. Apoptosis 10, 153-166.
  • Iordanov, M. S., Sundholm, A. J., Simpson, E. L., Hanifin, J. M., Ryabinina, O. P., Choi, R. J., Korcheva, V. B., Schneider, P., and Magun, B. E. (2005). Cell death-induced activation of epidermal growth factor receptor in keratinocytes: implications for restricting epidermal damage in dermatitis. J Invest Dermatol 125, 134-142.
  • Itoh, F., Itoh, S., Goumans, M. J., Valdimarsdottir, G., Iso, T., Dotto, G. P., Hamamori, Y., Kedes, L., Kato, M., and Dijke Pt, P. (2004). Synergy and antagonism between Notch and BMP receptor signaling pathways in endothelial cells. Embo J 23, 541-551.
  • Janssens, S., Tinel, A., Lippens, S., and Tschopp, J. (2005). PIDD mediates NF-kappaB activation in response to DNA damage. Cell 123, 1079-1092.
  • Jousson, O., Lechenne, B., Bontems, O., Capoccia, S., Mignon, B., Barblan, J., Quadroni, M., and Monod, M. (2004). Multiplication of an ancestral gene encoding secreted fungalysin preceded species differentiation in the dermatophytes Trichophyton and Microsporum. Microbiology 150, 301-310.
  • Kajava, A. V., Potekhin, S. A., Corradin, G., and Leapman, R. D. (2004). Organization of designed nanofibrils assembled from alpha-helical peptides as determined by electron microscopy. J Pept Sci 10, 291-297.
  • Kariminia, A., Bourreau, E., Pascalis, H., Couppie, P., Sainte-Marie, D., Tacchini-Cottier, F., and Launois, P. (2005). Transforming growth factor beta1 production by CD4(+) CD25(+) regulatory T cells in peripheral blood mononuclear cells from healthy subjects stimulated with Leishmania guyanensis. Infect Immun 73, 5908-5914.
  • Kataoka, T., and Tschopp, J. (2004). N-terminal fragment of c-FLIP(L) processed by caspase 8 specifically interacts with TRAF2 and induces activation of the NF-kappaB signaling pathway. Mol Cell Biol 24, 2627-2636.
  • Kunz, J. B., Schwarz, H., and Mayer, A. (2004). Determination of four sequential stages during microautophagy in vitro. J Biol Chem 279, 9987-9996.
  • Kvell, K., Nguyen, T. H., Salmon, P., Glauser, F., Werner-Favre, C., Barnet, M., Schneider, P., Trono, D., and Zubler, R. H. (2005). Transduction of CpG DNA-stimulated primary human B cells with bicistronic lentivectors. Mol Ther 12, 892-899.
  • Lang, K. S., Recher, M., Junt, T., Navarini, A. A., Harris, N. L., Freigang, S., Odermatt, B., Conrad, C., Ittner, L. M., Bauer, S., Luther, S. A., Uematsu, S., Akira, S., Hengartner, H., and Zinkernagel, R. M. (2005). Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease. Nat Med 11, 138-145.
  • Legler, D. F., Doucey, M. A., Schneider, P., Chapatte, L., Bender, F. C., and Bron, C. (2005). Differential insertion of GPI-anchored GFPs into lipid rafts of live cells. Faseb J 19, 73-75.
  • Legler, D. F., Johnson-Leger, C., Wiedle, G., Bron, C., and Imhof, B. A. (2004). The alpha v beta 3 integrin as a tumor homing ligand for lymphocytes. Eur J Immunol 34, 1608-1616.
  • LeibundGut-Landmann, S., Waldburger, J. M., Reis e Sousa, C., Acha-Orbea, H., and Reith, W. (2004). MHC class II expression is differentially regulated in plasmacytoid and conventional dendritic cells. Nat Immunol 5, 899-908.
  • Luzardo-Alvarez, A., Blarer, N., Peter, K., Romero, J. F., Reymond, C., Corradin, G., and Gander, B. (2005). Biodegradable microspheres alone do not stimulate murine macrophages in vitro, but prolong antigen presentation by macrophages in vitro and stimulate a solid immune response in mice. J Control Release 109, 62-76.
  • Mammucari, C., di Vignano, A. T., Sharov, A. A., Neilson, J., Havrda, M. C., Roop, D. R., Botchkarev, V. A., Crabtree, G. R., and Dotto, G. P. (2005). Integration of Notch 1 and calcineurin/NFAT signaling pathways in keratinocyte growth and differentiation control. Dev Cell 8, 665-676.
  • Martinon, F., Agostini, L., Meylan, E., and Tschopp, J. (2004). Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome. Curr Biol 14, 1929-1934.
  • Meraldi, V., Nebie, I., Tiono, A. B., Diallo, D., Sanogo, E., Theisen, M., Druilhe, P., Corradin, G., Moret, R., and Sirima, B. S. (2004). Natural antibody response to Plasmodium falciparum Exp-1, MSP-3 and GLURP long synthetic peptides and association with protection. Parasite Immunol 26, 265-272.
  • Meraldi, V., Romero, J. F., Kensil, C., and Corradin, G. (2005). A strong CD8+ T cell response is elicited using the synthetic polypeptide from the C-terminus of the circumsporozoite protein of Plasmodium berghei together with the adjuvant QS-21: quantitative and phenotypic comparison with the vaccine model of irradiated sporozoites. Vaccine 23, 2801-2812.
  • Meylan, E., Burns, K., Hofmann, K., Blancheteau, V., Martinon, F., Kelliher, M., and Tschopp, J. (2004). RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation. Nat Immunol 5, 503-507.
  • Meylan, E., Curran, J., Hofmann, K., Moradpour, D., Binder, M., Bartenschlager, R., and Tschopp, J. (2005). Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus. Nature 437, 1167-1172.
  • Monnerat, S., Martinez-Calvillo, S., Worthey, E., Myler, P. J., Stuart, K. D., and Fasel, N. (2004). Genomic organization and gene expression in a chromosomal region of Leishmania major. Mol Biochem Parasitol 134, 233-243.
  • Muller, S., Hoffmann, P., Esche, U. V., Mach, J. P., Gorczynski, R. M., Waelli, T., Alexander, C., Zahringer, U., Rietschel, E. T., Bessler, W. G., and Westphal, O. (2005). A fetal sheep liver extract containing immunostimulatory substances including LPS acts as leukocyte activator in cells of LPS responder and non responder mice. Int Immunopharmacol 5, 1809-1819.
  • Mustonen, T., Ilmonen, M., Pummila, M., Kangas, A. T., Laurikkala, J., Jaatinen, R., Pispa, J., Gaide, O., Schneider, P., Thesleff, I., and Mikkola, M. L. (2004). Ectodysplasin A1 promotes placodal cell fate during early morphogenesis of ectodermal appendages. Development 131, 4907-4919.
  • Nagorsen, D., Servis, C., Levy, N., Provenzano, M., Dudley, M. E., Marincola, F. M., and Levy, F. (2004). Proteasomal cleavage does not determine immunogenicity of gp100-derived peptides gp100 209-217 and gp100 209-217T210M. Cancer Immunol Immunother 53, 817-824.
  • Nakhaee, A., Taheri, T., Taghikhani, M., Mohebali, M., Salmanian, A. H., Fasel, N., and Rafati, S. (2004). Humoral and cellular immune responses against Type I cysteine proteinase of Leishmania infantum are higher in asymptomatic than symptomatic dogs selected from a naturally infected population. Vet Parasitol 119, 107-123.
  • Okuyama, R., LeFort, K., and Dotto, G. P. (2004). A dynamic model of keratinocyte stem cell renewal and differentiation: role of the p21WAF1/Cip1 and Notch1 signaling pathways. J Investig Dermatol Symp Proc 9, 248-252.
  • Okuyama, R., Nguyen, B. C., Talora, C., Ogawa, E., Tommasi di Vignano, A., Lioumi, M., Chiorino, G., Tagami, H., Woo, M., and Dotto, G. P. (2004). High commitment of embryonic keratinocytes to terminal differentiation through a Notch1-caspase 3 regulatory mechanism. Dev Cell 6, 551-562.
  • Owen, H. R., Quadroni, M., Bienvenut, W., Buerki, C., and Hottiger, M. O. (2005). Identification of novel and cell type enriched cofactors of the transcription activation domain of RelA (p65 NF-kappaB). J Proteome Res 4, 1381-1390.
  • Palagi, P. M., Walther, D., Quadroni, M., Catherinet, S., Burgess, J., Zimmermann-Ivol, C. G., Sanchez, J. C., Binz, P. A., Hochstrasser, D. F., and Appel, R. D. (2005). MSight: an image analysis software for liquid chromatography-mass spectrometry. Proteomics 5, 2381-2384.
  • Perrenoud, G., Messerli, F., Thierry, A. C., Beltraminelli, N., Cousin, P., Fasel, N., Vallet, V., Demotz, S., Duchosal, M. A., and Moulon, C. (2004). A recombinant rubella virus E1 glycoprotein as a rubella vaccine candidate. Vaccine 23, 480-488.
  • Peters, C., Baars, T. L., Buhler, S., and Mayer, A. (2004). Mutual control of membrane fission and fusion proteins. Cell 119, 667-678.
  • Peyre, M., Audran, R., Estevez, F., Corradin, G., Gander, B., Sesardic, D., and Johansen, P. (2004). Childhood and malaria vaccines combined in biodegradable microspheres produce immunity with synergistic interactions. J Control Release 99, 345-355.
  • Philippeaux, M. M., Pache, J. C., Dahoun, S., Barnet, M., Robert, J. H., Mauel, J., and Spiliopoulos, A. (2004). Establishment of permanent cell lines purified from human mesothelioma: morphological aspects, new marker expression and karyotypic analysis. Histochem Cell Biol 122, 249-260.
  • Prato, S., Maxwell, T., Pinzon-Charry, A., Schmidt, C. W., Corradin, G., and Lopez, J. A. (2005). MHC class I-restricted exogenous presentation of a synthetic 102-mer malaria vaccine polypeptide. Eur J Immunol 35, 681-689.
  • Rafati, S., Salmanian, A. H., Taheri, T., Masina, S., Schaff, C., Taslimi, Y., and Fasel, N. (2004). Type I signal peptidase from Leishmania is a target of the immune response in human cutaneous and visceral leishmaniasis. Mol Biochem Parasitol 135, 13-20.
  • Reese, C., Heise, F., and Mayer, A. (2005). Trans-SNARE pairing can precede a hemifusion intermediate in intracellular membrane fusion. Nature 436, 410-414.
  • Reese, C., and Mayer, A. (2005). Transition from hemifusion to pore opening is rate limiting for vacuole membrane fusion. J Cell Biol 171, 981-990.
  • Rumbo, M., Sierro, F., Debard, N., Kraehenbuhl, J. P., and Finke, D. (2004). Lymphotoxin beta receptor signaling induces the chemokine CCL20 in intestinal epithelium. Gastroenterology 127, 213-223.
  • Salzer, U., Chapel, H. M., Webster, A. D., Pan-Hammarstrom, Q., Schmitt-Graeff, A., Schlesier, M., Peter, H. H., Rockstroh, J. K., Schneider, P., Schaffer, A. A., Hammarstrom, L., and Grimbacher, B. (2005). Mutations in TNFRSF13B encoding TACI are associated with common variable immunodeficiency in humans. Nat Genet 37, 820-828.
  • Schneider, K., Kothlow, S., Schneider, P., Tardivel, A., Gobel, T., Kaspers, B., and Staeheli, P. (2004). Chicken BAFF--a highly conserved cytokine that mediates B cell survival. Int Immunol 16, 139-148.
  • Sedegah, M., Charoenvit, Y., Aguiar, J., Sacci, J., Hedstrom, R., Kumar, S., Belmonte, A., Lanar, D. E., Jones, T. R., Abot, E., Druilhe, P., Corradin, G., Epstein, J. E., Richie, T. L., Carucci, D. J., and Hoffman, S. L. (2004). Effect on antibody and T-cell responses of mixing five GMP-produced DNA plasmids and administration with plasmid expressing GM-CSF. Genes Immun 5, 553-561.
  • Singh, S., Soe, S., Mejia, J. P., Roussilhon, C., Theisen, M., Corradin, G., and Druilhe, P. (2004). Identification of a conserved region of Plasmodium falciparum MSP3 targeted by biologically active antibodies to improve vaccine design. J Infect Dis 190, 1010-1018.
  • Singh, S., Soe, S., Roussilhon, C., Corradin, G., and Druilhe, P. (2005). Plasmodium falciparum merozoite surface protein 6 displays multiple targets for naturally occurring antibodies that mediate monocyte-dependent parasite killing. Infect Immun 73, 1235-1238.
  • Suarez, M., Haenni, M., Canarelli, S., Fisch, F., Chodanowski, P., Servis, C., Michielin, O., Freitag, R., Moreillon, P., and Mermod, N. (2005). Structure-function characterization and optimization of a plant-derived antibacterial peptide. Antimicrob Agents Chemother 49, 3847-3857.
  • Tacchini-Cottier, F., Allenbach, C., Otten, L. A., and Radtke, F. (2004). Notch1 expression on T cells is not required for CD4+ T helper differentiation. Eur J Immunol 34, 1588-1596.
  • Tardivel, A., Tinel, A., Lens, S., Steiner, Q. G., Sauberli, E., Wilson, A., Mackay, F., Rolink, A. G., Beermann, F., Tschopp, J., and Schneider, P. (2004). The anti-apoptotic factor Bcl-2 can functionally substitute for the B cell survival but not for the marginal zone B cell differentiation activity of BAFF. Eur J Immunol 34, 509-518.
  • Teixeiro, E., Daniels, M. A., Hausmann, B., Schrum, A. G., Naeher, D., Luescher, I., Thome, M., Bragado, R., and Palmer, E. (2004). T cell division and death are segregated by mutation of TCRbeta chain constant domains. Immunity 21, 515-526.
  • Thorel, F., Constantinou, A., Dunand-Sauthier, I., Nouspikel, T., Lalle, P., Raams, A., Jaspers, N. G., Vermeulen, W., Shivji, M. K., Wood, R. D., and Clarkson, S. G. (2004). Definition of a short region of XPG necessary for TFIIH interaction and stable recruitment to sites of UV damage. Mol Cell Biol 24, 10670-10680.
  • Tinel, A., and Tschopp, J. (2004). The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress. Science 304, 843-846.
  • Uttenweiler, A., Schwarz, H., and Mayer, A. (2005). Microautophagic vacuole invagination requires calmodulin in a CA2+independent function. J Biol Chem 280, 33289-33297.
  • Wang, J., Devgan, V., Corrado, M., Prabhu, N. S., El-Deiry, W. S., Riccardi, C., Pandolfi, P. P., Missero, C., and Dotto, G. P. (2005). Glucocorticoid-induced tumor necrosis factor receptor is a p21Cip1/WAF1 transcriptional target conferring resistance of keratinocytes to UV light-induced apoptosis. J Biol Chem 280, 37725-37731.
  • Wu, W., Rinaldi, L., Fortner, K. A., Russell, J. Q., Tschopp, J., Irvin, C., and Budd, R. C. (2004). Cellular FLIP long form-transgenic mice manifest a Th2 cytokine bias and enhanced allergic airway inflammation. J Immunol 172, 4724-4732.



  • Corbett, M., and Kraehenbuhl, J. P. (2004). Lung immunity: necessity is the mother of induction. Nat Med 10, 904-905.
  • Corradin, G., and Giudice, G. (2005). Novel Adjuvants for Vaccines. Current Medicinal Chemistry - Anti-Inflammatory & Anti-Allergy Agents 4, 185-191.
  • Corradin, G., Spertini, F., and Verdini, A. (2004). Medicinal application of long synthetic peptide technology. Expert Opin Biol Ther 4, 1629-1639.
  • Debard, N., Py, P., Kraehenbuhl, J. P., and Fuchs, J. (2005). The influence of the Internet on immunology education. Nat Rev Immunol 5, 736-740.
  • Dotto, G. P., and Cotsarelis, G. (2005). Developmental biology. Rac1 up for epidermal stem cells. Science 309, 890-891.
  • Dotto, G. P., and Silke, J. (2004). More than cell death: caspases and caspase inhibitors on the move. Dev Cell 7, 2-3.
  • Gumy, A., Louis, J. A., and Launois, P. (2004). The murine model of infection with Leishmania major and its importance for the deciphering of mechanisms underlying differences in Th cell differentiation in mice from different genetic backgrounds. Int J Parasitol 34, 433-444.
  • Jousson, O., Lechenne, B., Bontems, O., Mignon, B., Reichard, U., Barblan, J., Quadroni, M., and Monod, M. (2004). Secreted subtilisin gene family in Trichophyton rubrum. Gene 339, 79-88.
  • Kraehenbuhl, J. P., and Corbett, M. (2004). Immunology. Keeping the gut microflora at bay. Science 303, 1624-1625.
  • Launois, P., and Tacchini-Cottier, F. (2004). Importance of neutrophils in the regulation of Leishmania major specific immune response. In Recent Res Devel Immunology, pp. 261-279.
  • Lefort, K., and Dotto, G. P. (2004). Notch signaling in the integrated control of keratinocyte growth/differentiation and tumor suppression. Semin Cancer Biol 14, 374-386.
  • LeibundGut-Landmann, S., Waldburger, J. M., Krawczyk, M., Otten, L. A., Suter, T., Fontana, A., Acha-Orbea, H., and Reith, W. (2004). Mini-review: Specificity and expression of CIITA, the master regulator of MHC class II genes. Eur J Immunol 34, 1513-1525.
  • Martinon, F., and Tschopp, J. (2004). Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases. Cell 117, 561-574.
  • Martinon, F., and Tschopp, J. (2005). NLRs join TLRs as innate sensors of pathogens. Trends Immunol 26, 447-454.
  • Meylan, E., and Tschopp, J. (2005). The RIP kinases: crucial integrators of cellular stress. Trends Biochem Sci 30, 151-159.
  • Muppidi, J. R., Tschopp, J., and Siegel, R. M. (2004). Life and death decisions: secondary complexes and lipid rafts in TNF receptor family signal transduction. Immunity 21, 461-465.
  • Niedergang, F., Didierlaurent, A., Kraehenbuhl, J. P., and Sirard, J. C. (2004). Dendritic cells: the host Achille's heel for mucosal pathogens? Trends Microbiol 12, 79-88.
  • Petrilli, V., Papin, S., and Tschopp, J. (2005). The inflammasome. Curr Biol 15, R581.
  • Quadroni, M., Ducret, A., and Stocklin, R. (2004). Quantify this! Report on a round table discussion on quantitative mass spectrometry in proteomics. Proteomics 4, 2211-2215.
  • Rueda, D., and Thome, M. (2005). Molecule page : Carma1. AfCS nature molecule pages. DOI:10.1038/mp.a003863.01
  • Rueda, D., and Thome, M. (2005). Phosphorylation of CARMA1: the link(er) to NF-kappaB activation. Immunity 23, 551-553.
  • Rumbo, M., Anderle, P., Didierlaurent, A., Sierro, F., Debard, N., Sirard, J. C., Finke, D., and Kraehenbuhl, J. P. (2004). How the gut links innate and adaptive immunity. Ann N Y Acad Sci 1029, 16-21.
  • Schneider, P. (2005). The role of APRIL and BAFF in lymphocyte activation. Curr Opin Immunol 17, 282-289.
  • Thome, M. (2004). CARMA1, BCL-10 and MALT1 in lymphocyte development and activation. Nat Rev Immunol 4, 348-359.


Book sections

  • Schneider, P. (2005). TNF family ligands and receptors in cell death signaling. In AACR Education book, pp. 279-284.
  • Schneider, P. (2004). Signaling by TNF and related ligands. In Inborn errors of development, C. Epstein, R. Erickson, and A. Wynshaw-Boris, eds. (Oxford, Oxford University Press), pp. 340-358.
  • Schneider, P. (2004). Tools for activation and neutralization of Fas signaling. In Fas signaling, H.Wajant, ed. (Georgetown,
  • Thome, M. (2004). Regulation of Fas signaling by FLIP proteins. In Fas signaling, H. Wajant, ed. (Landes Bioscience), pp. ch. 5.


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