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Modeling and treatment of neurodegenerative diseases

The general strategy of the group is to develop a pre-clinical research program on neurodegenerative diseases with  the development of relevant and predictive genetic models of CNS diseases (with a particular emphasis on Huntington's disease), investigation of disease mechanisms, identification and validation of therapeutic targets with a potential transfer to the clinic in collaboration with the Department of Clinical Neurosciences at the CHUV.

 

Formation of neuritic huntingtin aggregates in primary rat striatal neurons


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