Publications

Publications


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2012
Baitsch L., Fuertes-Marraco S.A., Legat A., Meyer C., Speiser D.E., 2012. The three main stumbling blocks for anticancer T cells. Trends in Immunology 33(7) pp. 364-372. [DOI] [Web of Science] [Pubmed]
Boller D., Doepfner K.T., DE Laurentiis A., Guerreiro A.S., Marinov M., Shalaby T., Depledge P., Robson A., Saghir N., Hayakawa M., Kaizawa H., Koizumi T., Ohishi T., Fattet S., Delattre O., Schweri-Olac A., Höland K., Grotzer M.A., Frei K., Spertini O., Waterfield M.D., Arcaro A., 2012. Targeting PI3KC2β Impairs Proliferation and Survival in Acute Leukemia, Brain Tumours and Neuroendocrine Tumours. Anticancer Research 32(8) pp. 3015-3027. [Web of Science] [Pubmed]
Greiner J., Ono Y., Hofmann S., Schmitt A., Mehring E., Götz M., Guillaume P., Döhner K., Mytilineos J., Döhner H., Schmitt M., 2012. Mutated regions of nucleophosmin 1 elicit both CD4+ and CD8+ T-cell responses in patients with acute myeloid leukemia. Blood 120(6) pp. 1282-1289. [DOI] [Web of Science] [Pubmed]
Röhrig U.F., Majjigapu S.R., Grosdidier A., Bron S., Stroobant V., Pilotte L., Colau D., Vogel P., Van den Eynde B.J., Zoete V., Michielin O., 2012. Rational design of 4-aryl-1,2,3-triazoles for indoleamine 2,3-dioxygenase 1 inhibition. Journal of Medicinal Chemistry 55(11) pp. 5270-5290. [DOI] [Web of Science] [Pubmed]
Romano E., Nardelli-Haefliger D., Donda A., Corgnac S., Romero P., 2012. SITC 26th annual meeting - summary. Journal of Translational Medicine 10(1) p. 105. [Document] [DOI] [Web of Science] [Pubmed]
2011
Valsesia A., Rimoldi D., Martinet D., Ibberson M., Benaglio P., Quadroni M., Waridel P., Gaillard M., Pidoux M., Rapin B., Rivolta C., Xenarios I., Simpson A.J., Antonarakis S.E., Beckmann J.S., Jongeneel C.V., Iseli C., Stevenson B.J., 2011. Network-guided analysis of genes with altered somatic copy number and gene expression reveals pathways commonly perturbed in metastatic melanoma. PLoS One 6(4) pp. e18369. [Document] [DOI] [Web of Science] [Pubmed]
2010
Ayyoub M., Dojcinovic D., Pignon P., Raimbaud I., Schmidt J., Luescher I., Valmori D., 2010. Monitoring of NY-ESO-1 specific CD4+ T cells using molecularly defined MHC class II/His-tag-peptide tetramers. Proceedings of the National Academy of Sciences of the United States of America 107(16) pp. 7437-7442. [DOI] [Web of Science] [Pubmed]
Ayyoub M., Pignon P., Dojcinovic D., Raimbaud I., Old L.J., Luescher I., Valmori D., 2010. Assessment of vaccine-induced CD4 T cell responses to the 119-143 immunodominant region of the tumor-specific antigen NY-ESO-1 using DRB1*0101 tetramers. Clinical Cancer Research 16(18) pp. 4607-4615. [DOI] [Web of Science] [Pubmed]
Back J., Scarpellino L., Held W., 2010. Probing the interactions of NK cell receptors with ligand expressed in trans and cis. Methods in Molecular Biology 612 pp. 313-323. [DOI] [Pubmed]
Baumann C., Lindholm C.K., Rimoldi D., Lévy F., 2010. The E3 ubiquitin ligase Itch regulates sorting nexin 9 through an unconventional substrate recognition domain. FEBS Journal 277(13) pp. 2803-2814. [DOI] [Web of Science] [Pubmed]
Caballero O.L., Zhao Q., Rimoldi D., Stevenson B.J., Svobodová S., Devalle S., Röhrig U.F., Pagotto A., Michielin O., Speiser D., Wolchok J.D., Liu C., Pejovic T., Odunsi K., Brasseur F., Van den Eynde B.J., Old L.J., Lu X., Cebon J., Strausberg R.L., Simpson A.J., 2010. Frequent MAGE mutations in human melanoma. PLoS One 5(9) pp. e12773. [DOI] [Web of Science] [Pubmed]
Cervantes-Barragan L., Züst R., Maier R., Sierro S., Janda J., Levy F., Speiser D., Romero P., Rohrlich P.S., Ludewig B., Thiel V., 2010. Dendritic cell-specific antigen delivery by coronavirus vaccine vectors induces long-lasting protective antiviral and antitumor immunity. MBIO 1(4) pp. e00171-10. [DOI] [Web of Science] [Pubmed]
Colliard A., Corbaz J., Salvioni P., Truong M.K., 07-2010. Motivation des patients à participer à un essai clinique de phase I en oncologie. in Congrès de l'Immersion Communautaire (ImCo). [Document]
Decrausaz L., Revaz V., Bobst M., Corthésy B., Romero P., Nardelli-Haefliger D., 2010. Induction of human papillomavirus oncogene-specific CD8 T-cell effector responses in the genital mucosa of vaccinated mice. International Journal of Cancer 126(10) pp. 2469-2478. [DOI] [Web of Science] [Pubmed]
Derré L., Jandus C., Baumgaertner P., Posevitz V., Devêvre E., Romero P., Speiser D.E., 2010. Quantitative multiparameter assays to measure the effect of adjuvants on human antigen-specific CD8 T-cell responses. Methods in Molecular Biology 626 pp. 231-249. [DOI] [Pubmed]
Derré L., Rivals J.P., Jandus C., Pastor S., Rimoldi D., Romero P., Michielin O., Olive D., Speiser D.E., 2010. BTLA mediates inhibition of human tumor-specific CD8+ T cells that can be partially reversed by vaccination. Journal of Clinical Investigation 120(1) pp. 157-167. [DOI] [Web of Science] [Pubmed]
Dumortier A., Durham A.D., Di Piazza M., Vauclair S., Koch U., Ferrand G., Ferrero I., Demehri S., Song L.L., Farr A.G., Leonard W.J., Kopan R., Miele L., Hohl D., Finke D., Radtke F., 2010. Atopic dermatitis-like disease and associated lethal myeloproliferative disorder arise from loss of Notch signaling in the murine skin. PLoS One 5(2) pp. e9258. [DOI] [Web of Science] [Pubmed]
Fayyad-Kazan H., Rouas R., Merimi M., El Zein N., Lewalle P., Jebbawi F., Mourtada M., Badran H., Ezzeddine M., Salaun B., Romero P., Burny A., Martiat P., Badran B., 2010. Valproate treatment of human cord blood CD4-positive effector T cells confers on them the molecular profile (microRNA signature and FOXP3 expression) of natural regulatory CD4-positive cells through inhibition of histone deacetylase. Journal of Biological Chemistry 285(27) pp. 20481-20491. [DOI] [Web of Science] [Pubmed]
Fourcade J., Sun Z., Benallaoua M., Guillaume P., Luescher I.F., Sander C., Kirkwood J.M., Kuchroo V., Zarour H.M., 2010. Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen-specific CD8+ T cell dysfunction in melanoma patients. Journal of Experimental Medicine 207(10) pp. 2175-2186. [DOI] [Web of Science] [Pubmed]
Guillaume P., Baumgaertner P., Neff L., Rufer N., Wettstein P., Speiser D.E., Luescher I.F., 2010. Novel soluble HLA-A2/MELAN-A complexes selectively stain a differentiation defective subpopulation of CD8+ T cells in patients with melanoma. International Journal of Cancer 127(4) pp. 910-923. [DOI] [Web of Science] [Pubmed]
Hodson D.J., Janas M.L., Galloway A., Bell S.E., Andrews S., Li C.M., Pannell R., Siebel C.W., MacDonald H.R., De Keersmaecker K., Ferrando A.A., Grutz G., Turner M., 2010. Deletion of the RNA-binding proteins ZFP36L1 and ZFP36L2 leads to perturbed thymic development and T lymphoblastic leukemia. Nature Immunology 11(8) pp. 717-724. [DOI] [Web of Science] [Pubmed]
Hor H., Kutalik Z., Dauvilliers Y., Valsesia A., Lammers G.J., Donjacour C.E., Iranzo A., Santamaria J., Peraita Adrados R., Vicario J.L., Overeem S., Arnulf I., Theodorou I., Jennum P., Knudsen S., Bassetti C., Mathis J., Lecendreux M., Mayer G., Geisler P., Benetó A., Petit B., Pfister C., Bürki J.V., Didelot G., Billiard M., Ercilla G., Verduijn W., Claas F.H., Vollenweider P., Waeber G., Waterworth D.M., Mooser V., Heinzer R., Beckmann J.S., Bergmann S., Tafti M., 2010. Genome-wide association study identifies new HLA class II haplotypes strongly protective against narcolepsy. Nature Genetics 42(9) pp. 786-789. [DOI] [Web of Science] [Pubmed]
Jeannet G., Boudousquié C., Gardiol N., Kang J., Huelsken J., Held W., 2010. Essential role of the Wnt pathway effector Tcf-1 for the establishment of functional CD8 T cell memory. Proceedings of the National Academy of Sciences of the United States of America 107(21) pp. 9777-9782. [DOI] [Pubmed]
Johannsen A., Genolet R., Legler D.F., Luther S.A., Luescher I.F., 2010. Definition of key variables for the induction of optimal NY-ESO-1-specific T cells in HLA transgene mice. Journal of Immunology 185(6) pp. 3445-3455. [DOI] [Web of Science] [Pubmed]
Kyewski B., Romero P., 2010. Chronic inflammation is regarded as a strong promoter of tumorigenesis. International Journal of Cancer 127(4) p. 747. [DOI] [Pubmed]
Laurent J., Speiser D.E., Appay V., Touvrey C., Vicari M., Papaioannou A., Canellini G., Rimoldi D., Rufer N., Romero P., Leyvraz S., Voelter V., 2010. Impact of 3 different short-term chemotherapy regimens on lymphocyte-depletion and reconstitution in melanoma patients. Journal of Immunotherapy 33(7) pp. 723-734. [DOI] [Web of Science] [Pubmed]
Laurenti E., Barde I., Verp S., Offner S., Wilson A., Quenneville S., Wiznerowicz M., Macdonald H.R., Trono D., Trumpp A., 2010. Inducible gene and shRNA expression in resident hematopoietic stem cells in vivo. Stem Cells 28(8) pp. 1390-1398. [DOI] [Web of Science] [Pubmed]
Muraoka D., Kato T., Wang L., Maeda Y., Noguchi T., Harada N., Takeda K., Yagita H., Guillaume P., Luescher I., Old L.J., Shiku H., Nishikawa H., 2010. Peptide vaccine induces enhanced tumor growth associated with apoptosis induction in CD8+ T cells. Journal of Immunology 185(6) pp. 3768-3776. [DOI] [Web of Science] [Pubmed]
Radtke F., Fasnacht N., Macdonald H.R., 2010. Notch signaling in the immune system. Immunity 32(1) pp. 14-27. [DOI] [Web of Science] [Pubmed]
Rama C.H., Villa L.L., Pagliusi S., Andreoli M.A., Costa M.C., Thomann P., Alves V.A., Longatto-Filho A., Eluf-Neto J., 2010. Opportunity for catch-up HPV vaccination in young women after first delivery. Journal of Epidemiology and Community Health 64(7) pp. 610-615. [DOI] [Web of Science] [Pubmed]
Ribeiro V.S., Hasan M., Wilson A., Boucontet L., Pereira P., Lesjean-Pottier S., Satoh-Takayama N., Di Santo J.P., Vosshenrich C.A., 2010. Cutting edge: thymic NK cells develop independently from T cell precursors. Journal of Immunology 185(9) pp. 4993-4997. [DOI] [Web of Science] [Pubmed]
Röhrig U.F., Awad L., Grosdidier A., Larrieu P., Stroobant V., Colau D., Cerundolo V., Simpson A.J., Vogel P., Van den Eynde B.J., Zoete V., Michielin O., 2010. Rational design of indoleamine 2,3-dioxygenase inhibitors. Journal of Medicinal Chemistry 53(3) pp. 1172-1189. [DOI] [Web of Science] [Pubmed]
Schmid D.A., Irving M.B., Posevitz V., Hebeisen M., Posevitz-Fejfar A., Sarria J.C., Gomez-Eerland R., Thome M., Schumacher T.N., Romero P., Speiser D.E., Zoete V., Michielin O., Rufer N., 2010. Evidence for a TCR affinity threshold delimiting maximal CD8 T cell function. Journal of Immunology 184(9) pp. 4936-4946. [DOI] [Web of Science] [Pubmed]
Schüpbach T., Zoete V., Tsakam-Sotché B., Michielin O., 2010. Fourier transform convolution integrals applied to generalized Born molecular volume. Journal of Computational Chemistry 31(3) pp. 649-659. [DOI] [Web of Science] [Pubmed]
Speiser D.E., Romero P., 2010. Molecularly defined vaccines for cancer immunotherapy, and protective T cell immunity. Seminars in Immunology 22(3) pp. 144-154. [DOI] [Web of Science] [Pubmed]
Speiser D.E., Romero P., 2010. Molecularly defined vaccines for cancer immunotherapy, and protective T cell immunity. Seminars in Immunology 22(3) pp. 144-154. [DOI] [Web of Science] [Pubmed]
Speiser D.E., Schwarz K., Baumgaertner P., Manolova V., Devevre E., Sterry W., Walden P., Zippelius A., Conzett K.B., Senti G., Voelter V., Cerottini J.P., Guggisberg D., Willers J., Geldhof C., Romero P., Kündig T., Knuth A., Dummer R., Trefzer U., Bachmann M.F., 2010. Memory and effector CD8 T-cell responses after nanoparticle vaccination of melanoma patients. Journal of Immunotherapy 33(8) pp. 848-858. [DOI] [Web of Science] [Pubmed]
Trumpp A., Essers M., Wilson A., 2010. Awakening dormant haematopoietic stem cells. Nature Reviews. Immunology 10(3) pp. 201-209. [DOI] [Web of Science] [Pubmed]
Van Maele L., Carnoy C., Cayet D., Songhet P., Dumoutier L., Ferrero I., Janot L., Erard F., Bertout J., Leger H., Sebbane F., Benecke A., Renauld J.C., Hardt W.D., Ryffel B., Sirard J.C., 2010. TLR5 signaling stimulates the innate production of IL-17 and IL-22 by CD3(neg)CD127+ immune cells in spleen and mucosa. Journal of Immunology 185(2) pp. 1177-1185. [DOI] [Web of Science] [Pubmed]
Voss R.H., Thomas S., Pfirschke C., Hauptrock B., Klobuch S., Kuball J., Grabowski M., Engel R., Guillaume P., Romero P., Huber C., Beckhove P., Theobald M., 2010. Coexpression of the T-cell receptor constant alpha domain triggers tumor reactivity of single-chain TCR-transduced human T cells. Blood 115(25) pp. 5154-5163. [DOI] [Web of Science] [Pubmed]
Walters R.G., Jacquemont S., Valsesia A., de Smith A.J., Martinet D., Andersson J., Falchi M., Chen F., Andrieux J., Lobbens S., Delobel B., Stutzmann F., El-Sayed Moustafa J.S., Chèvre J.C., Lecoeur C., Vatin V., Bouquillon S., Buxton J.L., Boute O., Holder-Espinasse M., Cuisset J.M., Lemaitre M.P., Ambresin A.E., Brioschi A., Gaillard M., Giusti V., Fellmann F., Ferrarini A., Hadjikhani N., Campion D., Guilmatre A., Goldenberg A., Calmels N., Mandel J.L., Le Caignec C., David A., Isidor B., Cordier M.P., Dupuis-Girod S., Labalme A., Sanlaville D., Béri-Dexheimer M., Jonveaux P., Leheup B., Ounap K., Bochukova E.G., Henning E., Keogh J., Ellis R.J., Macdermot K.D., van Haelst M.M., Vincent-Delorme C., Plessis G., Touraine R., Philippe A., Malan V., Mathieu-Dramard M., Chiesa J., Blaumeiser B., Kooy R.F., Caiazzo R., Pigeyre M., Balkau B., Sladek R., Bergmann S., Mooser V., Waterworth D., Reymond A., Vollenweider P., Waeber G., Kurg A., Palta P., Esko T., Metspalu A., Nelis M., Elliott P., Hartikainen A.L., McCarthy M.I., Peltonen L., Carlsson L., Jacobson P., Sjöström L., Huang N., Hurles M.E., O'Rahilly S., Farooqi I.S., Männik K., Jarvelin M.R., Pattou F., Meyre D., Walley A.J., Coin L.J., Blakemore A.I., Froguel P., Beckmann J.S., 2010. A new highly penetrant form of obesity due to deletions on chromosome 16p11.2. Nature 463(7281) pp. 671-675. [DOI] [Web of Science] [Pubmed]
Wendorff A.A., Koch U., Wunderlich F.T., Wirth S., Dubey C., Brüning J.C., MacDonald H.R., Radtke F., 2010. Hes1 is a critical but context-dependent mediator of canonical Notch signaling in lymphocyte development and transformation. Immunity 33(5) pp. 671-684. [DOI] [Pubmed]
Zhao D.M., Yu S., Zhou X., Haring J.S., Held W., Badovinac V.P., Harty J.T., Xue H.H., 2010. Constitutive activation of Wnt signaling favors generation of memory CD8 T cells. Journal of Immunology 184(3) pp. 1191-1199. [DOI] [Web of Science] [Pubmed]
Zoete V., Grosdidier A., Cuendet M., Michielin O., 2010. Use of the FACTS solvation model for protein-ligand docking calculations. Application to EADock. Journal of Molecular Recognition 23(5) pp. 457-461. [DOI] [Pubmed]
Zoete V., Irving M.B., Michielin O., 2010. MM-GBSA binding free energy decomposition and T cell receptor engineering. Journal of Molecular Recognition 23(2) pp. 142-152. [DOI] [Web of Science] [Pubmed]
2009
Angelov G.S., Guillaume P., Luescher I.F., 2009. CD8beta knockout mice mount normal anti-viral CD8+ T cell responses--but why? International Immunology 21(2) pp. 123-135. [DOI] [Web of Science] [Pubmed]
Back J., Malchiodi E.L., Cho S., Scarpellino L., Schneider P., Kerzic M.C., Mariuzza R.A., Held W., 2009. Distinct conformations of Ly49 natural killer cell receptors mediate MHC class I recognition in trans and cis. Immunity 31(4) pp. 598-608. [DOI] [Web of Science] [Pubmed]
Bioley G., Guillaume P., Luescher I., Yeh A., Dupont B., Bhardwaj N., Mears G., Old L.J., Valmori D., Ayyoub M., 2009. HLA class I - associated immunodominance affects CTL responsiveness to an ESO recombinant protein tumor antigen vaccine. Clinical cancer research 15(1) pp. 299-306. [DOI] [Web of Science] [Pubmed]
Bockamp E., Antunes C., Liebner S., Schmitt S., Cabezas-Wallscheid N., Heck R., Ohnngemach S., Oesch-Bartlomowicz B., Rickert C., Sanchez M.J., Hengstler J., Kaina B., Wilson A., Trumpp A., Eshkind L., 2009. In vivo fate mapping with SCL regulatory elements identifies progenitors for primitive and definitive hematopoiesis in mice. Mechanisms of Development 126(10) pp. 863-872. [DOI] [Web of Science] [Pubmed]
Brandes M., Willimann K., Bioley G., Lévy N., Eberl M., Luo M., Tampé R., Lévy F., Romero P., Moser B., 2009. Cross-presenting human gammadelta T cells induce robust CD8+ alphabeta T cell responses. Proceedings of the National Academy of Sciences of the United States of America 106(7) pp. 2307-2312. [DOI] [Web of Science] [Pubmed]
Bricard G., Cesson V., Devevre E., Bouzourene H., Barbey C., Rufer N., Im J.S., Alves P.M., Martinet O., Halkic N., Cerottini J.C., Romero P., Porcelli S.A., Macdonald H.R., Speiser D.E., 2009. Enrichment of human CD4+ V(alpha)24/Vbeta11 invariant NKT cells in intrahepatic malignant tumors. Journal of Immunology 182(8) pp. 5140-5151. [DOI] [Web of Science] [Pubmed]
Britten C.M., Janetzki S., Ben-Porat L., Clay T.M., Kalos M., Maecker H., Odunsi K., Pride M., Old L., Hoos A., Romero P., 2009. Harmonization guidelines for HLA-peptide multimer assays derived from results of a large scale international proficiency panel of the Cancer Vaccine Consortium. Cancer Immunology, Immunotherapy 58(10) pp. 1701-1713. [DOI] [Web of Science] [Pubmed]
Cerottini J.C., Romero P., 2009. Foreword. pp. v-vi in Jeannin J.F. (eds.) Lipid A in cancer therapy. Advances in Experimental Medicine and Biology 667. Springer, New York. [Pubmed]
Chalifour A., Scarpellino L., Back J., Brodin P., Devèvre E., Gros F., Lévy F., Leclercq G., Höglund P., Beermann F., Held W., 2009. A Role for cis Interaction between the Inhibitory Ly49A receptor and MHC class I for natural killer cell education. Immunity 30(3) pp. 337-347. [DOI] [Web of Science] [Pubmed]
Dimopoulos N., Jackson H.M., Ebert L., Guillaume P., Luescher I.F., Ritter G., Chen W., 2009. Combining MHC tetramer and intracellular cytokine staining for CD8(+) T cells to reveal antigenic epitopes naturally presented on tumor cells. Journal of immunological methods 340(1) pp. 90-94. [DOI] [Web of Science] [Pubmed]
Ebert L.M., Liu Y.C., Clements C.S., Robson N.C., Jackson H.M., Markby J.L., Dimopoulos N., Tan B.S., Luescher I.F., Davis I.D., Rossjohn J., Cebon J., Purcell A.W., Chen W., 2009. A long, naturally presented immunodominant epitope from NY-ESO-1 tumor antigen: implications for cancer vaccine design. Cancer research 69(3) pp. 1046-1054. [DOI] [Web of Science] [Pubmed]
Fiorini E., Merck E., Wilson A., Ferrero I., Jiang W., Koch U., Auderset F., Laurenti E., Tacchini-Cottier F., Pierres M., Radtke F., Luther S.A., Macdonald H.R., 2009. Dynamic regulation of notch 1 and notch 2 surface expression during T cell development and activation revealed by novel monoclonal antibodies. Journal of immunology 183(11) pp. 7212-7222. [DOI] [Web of Science] [Pubmed]
Fourcade J., Kudela P., Sun Z., Shen H., Land S.R., Lenzner D., Guillaume P., Luescher I.F., Sander C., Ferrone S., Kirkwood J.M., Zarour H.M., 2009. PD-1 is a regulator of NY-ESO-1-specific CD8+ T cell expansion in melanoma patients. Journal of immunology 182(9) pp. 5240-5249. [DOI] [Web of Science] [Pubmed]
Iancu E.M., Corthesy P., Baumgaertner P., Devevre E., Voelter V., Romero P., Speiser D.E., Rufer N., 06-2009. Clonotype selection and composition of human CD8 T cells specific for persistent herpes viruses varies with differentiation but is stable over time. Journal of immunology 183(1) pp. 319-331. [DOI] [Web of Science] [Pubmed]
Jandus C., Bioley G., Dojcinovic D., Derré L., Baitsch L., Wieckowski S., Rufer N., Kwok W.W., Tiercy J.M., Luescher I.F., Speiser D.E., Romero P., 2009. Tumor antigen-specific FOXP3+ CD4 T cells identified in human metastatic melanoma: peptide vaccination results in selective expansion of Th1-like counterparts. Cancer Research 69(20) pp. 8085-8093. [DOI] [Web of Science] [Pubmed]
Jandus C., Speiser D., Romero P., 2009. Recent advances and hurdles in melanoma immunotherapy. Pigment cell & melanoma research 22(6) pp. 711-723. [DOI] [Web of Science] [Pubmed]
Janetzki S., Britten C.M., Kalos M., Levitsky H.I., Maecker H.T., Melief C.J., Old L.J., Romero P., Hoos A., Davis M.M., 2009. "MIATA"-minimal information about T cell assays. Immunity 31(4) pp. 527-528. [DOI] [Web of Science] [Pubmed]
Klein O., Ebert L.M., Nicholaou T., Browning J., Russell S.E., Zuber M., Jackson H.M., Dimopoulos N., Tan B.S., Hoos A., Luescher I.F., Davis I.D., Chen W., Cebon J., 2009. Melan-A-specific cytotoxic T cells are associated with tumor regression and autoimmunity following treatment with anti-CTLA-4. Clinical cancer research 15(7) pp. 2507-2513. [DOI] [Web of Science] [Pubmed]
Krönig H., Hofer K., Conrad H., Guilaume P., Müller J., Schiemann M., Lennerz V., Cosma A., Peschel C., Busch D.H., Romero P., Bernhard H., 2009. Allorestricted T lymphocytes with a high avidity T-cell receptor towards NY-ESO-1 have potent anti-tumor activity. International journal of cancer. Journal international du cancer 125(3) pp. 649-655. [DOI] [Web of Science] [Pubmed]
Laurenti E., Wilson A., Trumpp A., 2009. Myc's other life: stem cells and beyond. Current opinion in cell biology 21(6) pp. 844-854. [DOI] [Pubmed]
Lienard D., Avril M.F., Le Gal F.A., Baumgaertner P., Vermeulen W., Blom A., Geldhof C., Rimoldi D., Pagliusi S., Romero P., Dietrich P.Y., Corvaia N., Speiser D.E., 2009. Vaccination of melanoma patients with Melan-A/Mart-1 peptide and Klebsiella outer membrane protein p40 as an adjuvant. Journal of immunotherapy 32(8) pp. 875-883. [DOI] [Web of Science] [Pubmed]
Michaeli Y., Denkberg G., Sinik K., Lantzy L., Chih-Sheng C., Beauverd C., Ziv T., Romero P., Reiter Y., 2009. Expression hierarchy of T cell epitopes from melanoma differentiation antigens: unexpected high level presentation of tyrosinase-HLA-A2 Complexes revealed by peptide-specific, MHC-restricted, TCR-like antibodies. Journal of immunology 182(10) pp. 6328-6341. [DOI] [Web of Science] [Pubmed]
Mycko M.P., Ferrero I., Wilson A., Jiang W., Bianchi T., Trumpp A., MacDonald H.R., 2009. Selective requirement for c-Myc at an early stage of V(alpha)14i NKT cell development. Journal of immunology 182(8) pp. 4641-4648. [DOI] [Web of Science] [Pubmed]
Neumann F., Sturm C., Hülsmeyer M., Dauth N., Guillaume P., Luescher I.F., Pfreundschuh M., Held G., 2009. Fab antibodies capable of blocking T cells by competitive binding have the identical specificity but a higher affinity to the MHC-peptide-complex than the T cell receptor. Immunology Letters 125(2) pp. 86-92. [DOI] [Web of Science] [Pubmed]
Noman M.Z., Buart S., Van Pelt J., Richon C., Hasmim M., Leleu N., Suchorska W.M., Jalil A., Lecluse Y., El Hage F., Giuliani M., Pichon C., Azzarone B., Mazure N., Romero P., Mami-Chouaib F., Chouaib S., 2009. The cooperative induction of hypoxia-inducible factor-1 alpha and STAT3 during hypoxia induced an impairment of tumor susceptibility to CTL-mediated cell lysis. Journal of immunology 182(6) pp. 3510-3521. [DOI] [Web of Science] [Pubmed]
Rettig L., McNeill L., Sarner N., Guillaume P., Luescher I., Tolaini M., Kioussis D., Zamoyska R., 2009. An essential role for the stalk region of CD8 beta in the coreceptor function of CD8. Journal of immunology 182(1) pp. 121-129. [Web of Science] [Pubmed]
Rio Frio T., Panek S., Iseli C., Di Gioia S.A., Kumar A., Gal A., Rivolta C., 2009. Ultra high throughput sequencing excludes MDH1 as candidate gene for RP28-linked retinitis pigmentosa. Molecular Vision 15 pp. 2627-2633. [Pubmed]
Röhrig U.F., Grosdidier A., Zoete V., Michielin O., 2009. Docking to heme proteins. Journal of Computational Chemistry 30(14) pp. 2305-2315. [DOI] [Web of Science] [Pubmed]
Rouas R., Fayyad-Kazan H., El Zein N., Lewalle P., Rothé F., Simion A., Akl H., Mourtada M., El Rifai M., Burny A., Romero P., Martiat P., Badran B., 2009. Human natural Treg microRNA signature: role of microRNA-31 and microRNA-21 in FOXP3 expression. European journal of immunology 39(6) pp. 1608-1618. [DOI] [Web of Science] [Pubmed]
Salaun B., Greutert M., Romero P., 2009. Toll-like receptor 3 is necessary for dsRNA adjuvant effects. Vaccine 27(12) pp. 1841-1847. [DOI] [Web of Science] [Pubmed]
Schmitt A., Barth T.F., Beyer E., Borchert F., Rojewski M., Chen J., Guillaume P., Gronau S., Greiner J., Möller P., Riechelmann H., Schmitt M., 2009. The tumor antigens RHAMM and G250/CAIX are expressed in head and neck squamous cell carcinomas and elicit specific CD8+ T cell responses. International journal of oncology 34(3) pp. 629-639. [Pubmed]
Touvrey C., Derré L., Devevre E., Corthesy P., Romero P., Rufer N., Speiser D.E., 06-2009. Dominant human CD8 T cell clonotypes persist simultaneously as memory and effector cells in memory phase. Journal of immunology 182(11) pp. 6718-6726. [DOI] [Web of Science] [Pubmed]
van der Wath R.C., Wilson A., Laurenti E., Trumpp A., Liò P., 2009. Estimating dormant and active hematopoietic stem cell kinetics through extensive modeling of bromodeoxyuridine label-retaining cell dynamics. PloS one 4(9) pp. e6972. [DOI] [Pubmed]
Von Moos R., Seifert B., Ochsenbein A., Cathomas R., Schlaeppi M., Gillessen S., Schuller J.C., Michielin O., Goldinger S., Dummer R., 2009. Temozolomide combined with bevacizumab in metastatic melanoma. A multicenter phase II trial (SAKK 50/07). pp. 13-14 in 15th ECCO/34th ESMO Multidisciplinary Congress. Ejc Supplements 7(3). [DOI] [Web of Science]
Wieckowski S., Baumgaertner P., Corthesy P., Voelter V., Romero P., Speiser D.E., Rufer N., 2009. Fine structural variations of alphabetaTCRs selected by vaccination with natural versus altered self-antigen in melanoma patients. Journal of Immunology 183(8) pp. 5397-5406. [DOI] [Web of Science] [Pubmed]
Zoete V., Grosdidier A., Michielin O., 2009. Docking, virtual high throughput screening and in silico fragment-based drug design. Journal of Cellular and Molecular Medicine 13(2) pp. 238-248. [DOI] [Web of Science] [Pubmed]
2008
Adams S., Lowes M.A., O'Neill D.W., Schachterle S., Romero P., Bhardwaj N., 2008. Lack of functionally active Melan-A(26-35)-specific T cells in the blood of HLA-A2+ vitiligo patients. Journal of Investigative Dermatology 128(8) pp. 1977-1980. [DOI] [Pubmed]
Alves P.M., Lévy N., Stevenson B.J., Bouzourene H., Theiler G., Bricard G., Viatte S., Ayyoub M., Vuilleumier H., Givel J.C., Rimoldi D., Speiser D.E., Jongeneel C.V., Romero P.J., Lévy F., 2008. Identification of tumor-associated antigens by large-scale analysis of genes expressed in human colorectal cancer. Cancer Immunity 8 p. 11. [Pubmed]
Brembilla N.C., Weber J., Rimoldi D., Pradervand S., Schütz F., Pantaleo G., Rüegg C., Quadroni M., Harshman K., Doucey M.A., 2008. c-Cbl expression levels regulate the functional responses of human central and effector memory CD4 T cells. Blood 112(3) pp. 652-660. [DOI] [Web of Science] [Pubmed]
Cesson V., Escher A., Piotet E., Rivals J. P., Speiser D., Bron L., Romero P., 2008. Analysis of naturally acquired CD4+T-cell responses to MAGE-A3 and MAGE-A4 cancer/testis antigens in patients with resected head and neck squamous cell carcinoma. pp. 53S-53S in Abstracts. Swiss Medical Weekly 138(Suppl. 163). [Web of Science]
Coudert J. D., Scarpellino L., Gros F., Vivier E., Held W., 2008. Sustained NKG2D engagement induces cross-tolerance of multiple distinct NK cell activation pathways. Blood 111(7) pp. 3571-3578. [DOI] [Web of Science] [Pubmed]
Cuendet M.A., Michielin O., 2008. Protein-protein interaction investigated by steered molecular dynamics: the TCR-pMHC complex. Biophysical journal 95(8) pp. 3575-3590. [DOI] [Web of Science] [Pubmed]
Derré L., Bruyninx M., Baumgaertner P., Ferber M., Schmid D., Leimgruber A., Zoete V., Romero P., Michielin O., Speiser D.E., Rufer N., 2008. Distinct sets of alphabeta TCRs confer similar recognition of tumor antigen NY-ESO-1157-165 by interacting with its central Met/Trp residues. Proceedings of the National Academy of Sciences of the United States of America 105(39) pp. 15010-15015. [DOI] [Web of Science] [Pubmed]
Dummer R., Rochlitz C., Velu T., Acres B., Limacher J.M., Bleuzen P., Lacoste G., Slos P., Romero P., Urosevic M., 2008. Intralesional adenovirus-mediated interleukin-2 gene transfer for advanced solid cancers and melanoma. Molecular Therapy 16(5) pp. 985-994. [DOI] [Web of Science] [Pubmed]
Fiechter V., Cameroni E., Cerutti L., De V. C., Barral Y., Fankhauser C., 2008. The evolutionary conserved BER1 gene is involved in microtubule stability in yeast. Current Genetics 53(2) pp. 107-115. [DOI] [Web of Science] [Pubmed]
Fiorini E., Ferrero I., Merck E., Favre S., Pierres M., Luther S.A., MacDonald H.R., 2008. Cutting edge: thymic crosstalk regulates delta-like 4 expression on cortical epithelial cells. Journal of Immunology 181(12) pp. 8199-8203. [Web of Science] [Pubmed]
Garcia Casado J., Janda J., Wei J., Chapatte L., Colombetti S., Alves P., Ritter G., Ayyoub M., Valmori D., Chen W., Lévy F., 2008. Lentivector immunization induces tumor antigen-specific B and T cell responses in vivo. European Journal of Immunology 38(7) pp. 1867-1876. [DOI] [Web of Science] [Pubmed]
Held W., 2008. Inhibitions in NK-cell maturation. Blood 112(1) pp. 8-9. [DOI] [Web of Science] [Pubmed]
Held W., 2008. Tolerance and reactivity of NK cells: two sides of the same coin? European Journal of Immunology 38(11) pp. 2930-2933. [DOI] [Pubmed]
Held W., Mariuzza R.A., 2008. Cis interactions of immunoreceptors with MHC and non-MHC ligands. Nature Reviews. Immunology 8(4) pp. 269-278. [DOI] [Web of Science] [Pubmed]
Hofmann O., Caballero O.L., Stevenson B.J., Chen Y.T., Cohen T., Chua R., Maher C.A., Panji S., Schaefer U., Kruger A., Lehvaslaiho M., Carninci P., Hayashizaki Y., Jongeneel C.V., Simpson A.J., Old L.J., Hide W., 2008. Genome-wide analysis of cancer/testis gene expression. Proceedings of the National Academy of Sciences of the United States of America 105(51) pp. 20422-20427. [DOI] [Pubmed]
Iancu Emanuela M., Speiser Daniel E., Rufer Nathalie, 2008. Assessing ageing of individual T lymphocytes: Mission impossible? Mechanisms of Ageing and Development 129(1-2) pp. 67-78. [DOI] [Web of Science]
Jandus C., Bioley G., Rivals J.P., Dudler J., Speiser D., Romero P., 2008. Increased numbers of circulating polyfunctional Th17 memory cells in patients with seronegative spondylarthritides. Arthritis and Rheumatism 58(8) pp. 2307-2317. [DOI] [Web of Science] [Pubmed]
Jandus C., Bioley G., Speiser D.E., Romero P., 2008. Selective accumulation of differentiated FOXP3(+) CD4 (+) T cells in metastatic tumor lesions from melanoma patients compared to peripheral blood. Cancer Immunology, Immunotherapy 57(12) pp. 1795-1805. [DOI] [Web of Science] [Pubmed]
Janetzki S., Panageas K.S., Ben-Porat L., Boyer J., Britten C.M., Clay T.M., Kalos M., Maecker H.T., Romero P., Yuan J., Kast W.M., Hoos A., 2008. Results and harmonization guidelines from two large-scale international Elispot proficiency panels conducted by the Cancer Vaccine Consortium (CVC/SVI). Cancer immunology, immunotherapy 57(3) pp. 303-315. [DOI] [Web of Science] [Pubmed]
Jeannet G., Scheller M., Scarpellino L., Duboux S., Gardiol N., Back J., Kuttler F., Malanchi I., Birchmeier W., Leutz A., Huelsken J., Held W., 2008. Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin. Blood 111(1) pp. 142-149. [DOI] [Web of Science] [Pubmed]
Koch U., Fiorini E., Benedito R., Besseyrias V., Schuster-Gossler K., Pierres M., Manley N.R., Duarte A., Macdonald H.R., Radtke F., 2008. Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment. The Journal of experimental medicine 205(11) pp. 2515-2523. [DOI] [Web of Science] [Pubmed]
Koch U., Wilson A., Cobas M., Kemler R., Macdonald H.R., Radtke F., 2008. Simultaneous loss of beta- and gamma-catenin does not perturb hematopoiesis or lymphopoiesis. Blood 111(1) pp. 160-164. [DOI] [Web of Science] [Pubmed]
Laurenti E., Varnum-Finney B., Wilson A., Ferrero I., Blanco-Bose W.E., Ehninger A., Knoepfler P.S., Cheng P.F., MacDonald H.R., Eisenman R.N., Bernstein I.D., Trumpp A., 2008. Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity. Cell stem cell 3(6) pp. 611-624. [DOI] [Web of Science] [Pubmed]
Mahnke Y., Devevre E., Baurngaertner P., Matter M., Rufer N., Rorner P., Speiser D., 2008. Tumour antigen specific CD8+T-cells from melanoma patients exert strong ex-vivo cytolytic activity. pp. 17S in Annual Joint Meeting of the Swiss Societies for Pneumology, Paediatric Pneumology, Allergology and Immunology, Thoracic Surgery. Swiss Medical Weekly 138(Suppl. 163). [Web of Science]
Michielin O., Rufer N., Romero P., Laurent J., Cerottini J.P., Gugisberg D., Leyvraz S., Speiser D., 2008. Nouveautés dans l'immunothérapie du cancer [New developments in cancer immunotherapy]. Revue Médicale Suisse 4(158) pp. 1248-1251. [Pubmed]
Rivals J.P., Cesson V., Rimoldi D., Seelentag W., Speiser D., Romero P., Monnier P., Bron L., 2008. Assessment of immune suppressive circuits in the tumour micro-environment of human head and neck squamous cell carcinoma (HNSCC). pp. 58S in Annual Joint Meeting of the Swiss Societies for Pneumology, Paediatric Pneumology, Allergology and Immunology, Thoracic Surgery. Swiss Medical Weekly 138(Suppl. 163). [Web of Science]
Rochat B., Zoete V., Grosdidier A., von Grünigen S., Marull M., Michielin O., 2008. In vitro biotransformation of imatinib by the tumor expressed CYP1A1 and CYP1B1. Biopharmaceutics and drug disposition 29(2) pp. 103-118. [DOI] [Web of Science] [Pubmed]
Romero P., 2008. Current state of vaccine therapies in non-small-cell lung cancer. Clinical Lung Cancer 9(Suppl. 1) pp. S28-S36. [DOI] [Web of Science] [Pubmed]
Sauvain M.O., Dorr A.P., Stevenson B., Quazzola A., Naef F., Wiznerowicz M., Schütz F., Jongeneel V., Duboule D., Spitz F., Trono D., 2008. Genotypic features of lentivirus transgenic mice. Journal of Virology 82(14) pp. 7111-7119. [DOI] [Pubmed]
Segura J.M., Guillaume P., Mark S., Dojcinovic D., Johannsen A., Bosshard G., Angelov G., Legler D.F., Vogel H., Luescher I.F., 2008. Increased mobility of major histocompatibility complex I-peptide complexes decreases the sensitivity of antigen recognition. Journal of Biological Chemistry 283(35) pp. 24254-24263. [DOI] [Web of Science] [Pubmed]
Speiser D. E., Baumgaertner P., Voelter V., Devevre E., Barbey C., Rufer N., Romero P., 2008. Unmodified self antigen triggers human CD8 T cells with stronger tumor reactivity than altered antigen. Proceedings of the National Academy of Sciences of the United States of America 105(10) pp. 3849-3854. [DOI] [Web of Science] [Pubmed]
Stirnemann K., Romero J. F., Baldi L., Robert B., Cesson V., Besra G. S., Zauderer M., Wurm F., Corradin G., Mach J. P., Macdonald H. R., Donda A., 2008. Sustained activation and tumor targeting of NKT cells using a CD1d-anti-HER2-scFv fusion protein induce antitumor effects in mice. Journal of Clinical Investigation 118(3) pp. 994-1005. [DOI] [Web of Science] [Pubmed]
Touvrey C., Derre L., Rufer N., Romero P., Speiser D., 2008. Ex-vivo cytotoxic function by influenza specific CD8 effector T-cells from healthy humans in memory phase : P219. pp. 50S-51S in Annual Joint Meeting of the Swiss Societies for Pneumology, Paediatric Pneumology, Allergology and Immunology, Thoracic Surgery. Swiss Medical Weekly 138(Suppl. 163). [Web of Science]
Van Den Broeck T., Stevenaert F., Taveirne S., Debacker V., Vangestel C., Vandekerckhove B., Taghon T., Matthys P., Plum J., Held W., Dewerchin M., Yokoyama W.M., Leclercq G., 2008. Ly49E-dependent inhibition of natural killer cells by urokinase plasminogen activator. Blood 112(13) pp. 5046-5051. [DOI] [Web of Science] [Pubmed]
Voelter V., Diserens A.C., Moulin A., Nagel G., Yan P., Migliavacca E., Rimoldi D., Hamou M.F., Kaina B., Leyvraz S., Hegi M.E., 2008. Infrequent promoter methylation of the MGMT gene in liver metastases from uveal melanoma. International Journal of Cancer 123(5) pp. 1215-1218. [DOI] [Web of Science] [Pubmed]
Voelter V., Pica A., Laurent J., Rimoldi D., Bouzourene H., Sajadi A., Matter M., Romero P., Rufer N., Speiser D.E., 2008. An unusual case of metastatic melanoma sensitive to chemotherapy and immunotherapy, with late immune escape in the brain. Cancer Immunity 8 p. 6. [Pubmed]
Voelter V., Rufer N., Reynard S., Greub G., Brookes R., Guillaume P., Grosjean F., Fagerberg T., Michielin O., Rowland-Jones S., Pinilla C., Leyvraz S., Romero P., Appay V., 2008. Characterization of Melan-A reactive memory CD8+ T cells in a healthy donor. International Immunology 20(8) pp. 1087-1096. [DOI] [Web of Science] [Pubmed]
Voss R.H., Willemsen R.A., Kuball J., Grabowski M., Engel R., Intan R.S., Guillaume P., Romero P., Huber C., Theobald M., 2008. Molecular design of the Calphabeta interface favors specific pairing of introduced TCRalphabeta in human T cells. Journal of Immunology 180(1) pp. 391-401. [Web of Science] [Pubmed]
Wilson A., Laurenti E., Oser G., van der Wath R. C., Blanco-Bose W., Jaworski M., Offner S., Dunant C. F., Eshkind L., Bockamp E., Lio P., Macdonald H. R., Trumpp A., 2008. Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair. Cell 135(6) pp. 1118-1129. [DOI] [Web of Science] [Pubmed]
2007
Alves P.M., Lévy N., Bouzourene H., Viatte S., Bricard G., Ayyoub M., Vuilleumier H., Givel J.C., Halkic N., Speiser D.E., Romero P., Lévy F., 2007. Molecular and immunological evaluation of the expression of cancer/testis gene products in human colorectal cancer. Cancer immunology, immunotherapy 56(6) pp. 839-847. [DOI] [Web of Science] [Pubmed]
Alves P.M., Viatte S., Fagerberg T., Michielin O., Bricard G., Bouzourene H., Vuilleumier H., Kruger T., Givel J.C., Lévy F., Speiser D.E., Cerottini J.C., Romero P., 2007. Immunogenicity of the carcinoembryonic antigen derived peptide 694 in HLA-A2 healthy donors and colorectal carcinoma patients. Cancer immunology, immunotherapy 56(11) pp. 1795-1805. [DOI] [Web of Science] [Pubmed]
Amsen D., Antov A., Jankovic D., Sher A., Radtke F., Souabni A., Busslinger M., McCright B., Gridley T., Flavell R. A., 07-2007. Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch. Immunity 27(1) pp. 89-99. [DOI] [Pubmed]
Appay V., Voelter V., Rufer N., Reynard S., Jandus C., Gasparini D., Lienard D., Speiser D.E., Schneider P., Cerottini J.C., Romero P., Leyvraz S., 2007. Combination of transient lymphodepletion with busulfan and fludarabine and peptide vaccination in a phase I clinical trial for patients with advanced melanoma. Journal of Immunotherapy 30(2) pp. 240-250. [DOI] [Web of Science] [Pubmed]
Back J., Chalifour A., Scarpellino L., Held W., 2007. Stable masking by H-2Dd cis ligand limits Ly49A relocalization to the site of NK cell/target cell contact. Proceedings of the National Academy of Sciences of the United States of America 104(10) pp. 3978-3983. [DOI] [Web of Science] [Pubmed]
Barbey C., Baumgaertner P., Devevre E., Rubio-Godoy V., Derre L., Bricard G., Guillaume P., Luescher I.F., Liénard D., Cerottini J.C., Romero P., Rufer N., Speiser D.E., 2007. IL-12 controls cytotoxicity of a novel subset of self-antigen-specific human CD28+ cytolytic T cells. Journal of Immunology 178(6) pp. 3566-3574. [Web of Science] [Pubmed]
Besseyrias V., Fiorini E., Strobl L.J., Zimber-Strobl U., Dumortier A., Koch U., Arcangeli M.L., Ezine S., Macdonald H.R., Radtke F., 2007. Hierarchy of Notch-Delta interactions promoting T cell lineage commitment and maturation. The Journal of experimental medicine 204(2) pp. 331-343. [DOI] [Web of Science] [Pubmed]
Butticaz C., Michielin O., Wyniger J., Telenti A., Rothenberger S., 2007. Silencing of both beta-TrCP1 and HOS (beta-TrCP2) is required to suppress human immunodeficiency virus type 1 Vpu-mediated CD4 down-modulation. Journal of virology 81(3) pp. 1502150-5. [DOI] [Web of Science] [Pubmed]
Derré L., Bruyninx M., Baumgaertner P., Devevre E., Corthesy P., Touvrey C., Mahnke Y.D., Pircher H., Voelter V., Romero P., Speiser D.E., Rufer N., 2007. In Vivo Persistence of Codominant Human CD8+ T Cell Clonotypes Is Not Limited by Replicative Senescence or Functional Alteration. Journal of Immunology 179(4) pp. 2368-2379. [Web of Science] [Pubmed]
Derré L., Ferber M., Touvrey C., Devevre E., Zoete V., Leimgruber A., Romero P., Michielin O., Lévy F., Speiser D.E., 2007. A novel population of human melanoma-specific CD8 T cells recognizes Melan-AMART-1 immunodominant nonapeptide but not the corresponding decapeptide. Journal of Immunology 179(11) pp. 7635-7645. [Web of Science] [Pubmed]
Feige J.N., Gelman L., Rossi D., Zoete V., Métivier R., Tudor C., Anghel S.I., Grosdidier A., Lathion C., Engelborghs Y., Michielin O., Wahli W., Desvergne B., 2007. The endocrine disruptor monoethyl-hexyl-phthalate is a selective peroxisome proliferator-activated receptor gamma modulator that promotes adipogenesis. Journal of Biological Chemistry 282(26) pp. 19152-19166. [DOI] [Web of Science] [Pubmed]
Ferrero I., Grosjean F., Fiorini E., MacDonald H.R., 2007. A critical lineage-nonspecific role for pTalpha in mediating allelic and isotypic exclusion in TCRbeta-transgenic mice. European journal of immunology 37(11) pp. 3220-3228. [DOI] [Web of Science] [Pubmed]
Iancu E.M., Speiser D.E., Rufer N., 2007. Assessing ageing of individual T lymphocytes: mission impossible? Mechanisms of ageing and development 129(1-2) pp. 67-78. [DOI] [Web of Science] [Pubmed]
Iero M., Squarcina P., Romero P., Guillaume P., Scarselli E., Cerino R., Carrabba M., Toutirais O., Parmiani G., Rivoltini L., 2007. Low TCR avidity and lack of tumor cell recognition in CD8(+) T cells primed with the CEA-analogue CAP1-6D peptide. Cancer immunology, immunotherapy 56(12) pp. 1979-1991. [DOI] [Web of Science] [Pubmed]
Iseli C., Ambrosini G., Bucher P., Jongeneel C.V., 2007. Indexing strategies for rapid searches of short words in genome sequences. PLoS ONE 2(6) pp. e579. [Document] [DOI] [Pubmed]
Jorritsma A., Gomez-Eerland R., Dokter M., van de Kasteele W., Zoet Y.M., Doxiadis I.I., Rufer N., Romero P., Morgan R.A., Schumacher T.N., Haanen J.B., 2007. Selecting highly affine and well-expressed TCRs for gene therapy of melanoma. Blood 110(10) pp. 3564-72. [DOI] [Web of Science] [Pubmed]
Kelly A. P., Finlay D. K., Hinton H. J., Clarke R. G., Fiorini E., Radtke F., Cantrell D. A., 07-2007. Notch-induced T cell development requires phosphoinositide-dependent kinase 1. EMBO Journal 26(14) pp. 3441-50. [DOI] [Pubmed]
Koch U., Radtke F., 08-2007. Haematopoietic stem cell niche in Drosophila. Bioessays 29(8) pp. 713-6. [DOI] [Pubmed]
Koch U., Radtke F., 08-2007. Notch and cancer: a double-edged sword. Cellular and Molecular Life Sciences . [DOI] [Pubmed]
Komine O., Nagaoka M., Watase K., Gutmann D. H., Tanigaki K., Honjo T., Radtke F., Saito T., Chiba S., Tanaka K., 08-2007. The monolayer formation of Bergmann glial cells is regulated by Notch/RBP-J signaling. Developmental Biology . [DOI] [Pubmed]
Le Gal F.A., Widmer V.M., Dutoit V., Rubio-Godoy V., Schrenzel J., Walker P.R., Romero P.J., Valmori D., Speiser D.E., Dietrich P.Y., 2007. Tissue homing and persistence of defined antigen-specific CD8+ tumor-reactive T-cell clones in long-term melanoma survivors. The Journal of investigative dermatology 127(3) pp. 622-629. [DOI] [Web of Science] [Pubmed]
Lejeune F. J., Rimoldi D., Speiser D., 05-2007. New approaches in metastatic melanoma: biological and molecular targeted therapies. Expert Review of Anticancer Therapy 7(5) pp. 701-13. [DOI] [Web of Science] [Pubmed]
Macdonald H.R., 2007. NKT cells: In the beginning... European journal of immunology 37 Suppl 1 pp. S111-115. [DOI] [Web of Science] [Pubmed]
MacDonald H.R., Mycko M.P., 2007. Development and selection of Valpha l4i NKT cells. Current topics in microbiology and immunology 314 pp. 195-212. [Web of Science] [Pubmed]
Matter M., Nicod Lalonde M., Allaoua M., Boubaker A., Liénard D., Gugerli O., Cerottini J.P., Bouzourene H., Bischof Delaloye A., Lejeune F., 2007. The role of interval nodes in sentinel lymph node mapping and dissection for melanoma patients. Journal of Nuclear Medicine 48(10) pp. 1607-1613. [DOI] [Web of Science] [Pubmed]
Meijer S.L., Dols A., Jensen S.M., Hu H.M., Miller W., Walker E., Romero P., Fox B.A., Urba W.J., 2007. Induction of circulating tumor-reactive CD8+ T cells after vaccination of melanoma patients with the gp100 209-2M peptide. Journal of immunotherapy 30(5) pp. 533-543. [DOI] [Web of Science] [Pubmed]
Melichar H.J., Narayan K., Der S.D., Hiraoka Y., Gardiol N., Jeannet G., Held W., Chambers C.A., Kang J., 2007. Regulation of gammadelta versus alphabeta T lymphocyte differentiation by the transcription factor SOX13. Science 315(5809) pp. 230-233. [DOI] [Web of Science] [Pubmed]
Michalik L., Zoete V., Krey G., Grosdidier A., Gelman L., Chodanowski P., Feige J.N., Desvergne B., Wahli W., Michielin O., 2007. Combined simulation and mutagenesis analyses reveal the involvement of key residues for peroxisome proliferator-activated receptor alpha helix 12 dynamic behavior. Journal of Biological Chemistry 282(13) pp. 9666-9677. [DOI] [Web of Science] [Pubmed]
Minguet S., Swamy M., Alarcón B., Luescher I.F., Schamel W.W., 2007. Full activation of the T cell receptor requires both clustering and conformational changes at CD3. Immunity 26(1) pp. 43-54. [DOI] [Web of Science] [Pubmed]
Moretti S., Armougom F., Wallace I.M., Higgins D.G., Jongeneel C.V., Notredame C., 2007. The M-Coffee web server: a meta-method for computing multiple sequence alignments by combining alternative alignment methods. Nucleic Acids Research 35(Web Server issue) pp. W645-8. [DOI] [Web of Science] [Pubmed]
Pagni M., Ioannidis V., Cerutti L., Zahn-Zabal M., Jongeneel C.V., Hau J., Martin O., Kuznetsov D., Falquet L., 2007. MyHits: improvements to an interactive resource for analyzing protein sequences. Nucleic Acids Research 35(Web Server issue) pp. W433-W437. [DOI] [Web of Science] [Pubmed]
Pittet M.J., Grimm J., Berger C.R., Tamura T., Wojtkiewicz G., Nahrendorf M., Romero P., Swirski F.K., Weissleder R., 2007. In vivo imaging of T cell delivery to tumors after adoptive transfer therapy. Proceedings of the National Academy of Sciences of the United States of America 104(30) pp. 12457-12461. [DOI] [Web of Science] [Pubmed]
Retelska D., Beaudoing E., Notredame C., Jongeneel C.V., Bucher P., 2007. Vertebrate conserved non coding DNA regions have a high persistence length and a short persistence time. BMC Genomics 8(1) p. 398. [Document] [DOI] [Web of Science] [Pubmed]
Romero P., Zippelius A., Kurth I., Pittet M.J., Touvrey C., Iancu E.M., Corthesy P., Devevre E., Speiser D.E., Rufer N., 2007. Four functionally distinct populations of human effector-memory CD8+ T lymphocytes. Journal of Immunology 178(7) pp. 4112-4119. [Web of Science] [Pubmed]
Salaun B., Lebecque S., Matikainen S., Rimoldi D., Romero P., 2007. Toll-like receptor 3 expressed by melanoma cells as a target for therapy? Clinical cancer research 13(15 Pt 1) pp. 4565-4574. [DOI] [Web of Science] [Pubmed]
Santos M. A., Sarmento L. M., Rebelo M., Doce A. A., Maillard I., Dumortier A., Neves H., Radtke F., Pear W. S., Parreira L., Demengeot J., 09-2007. Notch1 engagement by Delta-like-1 promotes differentiation of B lymphocytes to antibody-secreting cells. Proceedings of the National Academy of Sciences of the United States of America 104(39) pp. 15454-9. [DOI] [Pubmed]
Scarpellino L., Oeschger F., Guillaume P., Coudert J.D., Lévy F., Leclercq G., Held W., 2007. Interactions of Ly49 family receptors with MHC class I ligands in trans and cis. Journal of immunology 178(3) pp. 1277-1284. [Web of Science] [Pubmed]
Schmitz-Winnenthal F.H., Galindo-Escobedo L.V., Rimoldi D., Geng W., Romero P., Koch M., Weitz J., Krempien R., Niethammer A.G., Beckhove P., Buchler M.W., Z'graggen K., 2007. Potential target antigens for immunotherapy in human pancreatic cancer. Cancer letters 252(2) pp. 290-298. [DOI] [Web of Science] [Pubmed]
Schouwey K., Delmas V., Larue L., Zimber-Strobl U., Strobl L. J., Radtke F., Beermann F., 01-2007. Notch1 and Notch2 receptors influence progressive hair graying in a dose-dependent manner. Developmental Dynamics 236(1) pp. 282-9. [DOI] [Pubmed]
Stevenson B.J., Iseli C., Panji S., Zahn-Zabal M., Hide W., Old L.J., Simpson A.J., Jongeneel C.V., 2007. Rapid evolution of cancer/testis genes on the X chromosome. BMC Genomics 8 p. 129. [Document] [DOI] [Web of Science] [Pubmed]
Stupp R., Pica A., Mirimanoff R.O., Michielin O., 2007. Un guide pratique au traitement des gliomes [A practical guide for the management of gliomas]. Bulletin du cancer 94(9) pp. 817-22. [DOI] [Web of Science] [Pubmed]
Takeshita K., Satoh M., Ii M., Silver M., Limbourg F. P., Mukai Y., Rikitake Y., Radtke F., Gridley T., Losordo D. W., Liao J. K., 01-2007. Critical role of endothelial Notch1 signaling in postnatal angiogenesis. Circulation Research 100(1) pp. 70-8. [DOI] [Pubmed]
Valmori D., Levy F., Godefroy E., Scotto L., Souleimanian N. E., Karbach J., Tosello V., Hesdorffer C. S., Old L. J., Jager E., Ayyoub M., 02-2007. Epitope clustering in regions undergoing efficient proteasomal processing defines immunodominant CTL regions of a tumor antigen. Clinical Immunology 122(2) pp. 163-72. [DOI] [Web of Science] [Pubmed]
Vauclair S., Majo F., Durham A. D., Ghyselinck N. B., Barrandon Y., Radtke F., 08-2007. Corneal epithelial cell fate is maintained during repair by Notch1 signaling via the regulation of vitamin A metabolism. Developmental Cell 13(2) pp. 242-53. [DOI] [Web of Science] [Pubmed]
Wilson A., Ardiet D.L., Saner C., Vilain N., Beermann F., Aguet M., Macdonald H.R., Zilian O., 2007. Normal hemopoiesis and lymphopoiesis in the combined absence of numb and numblike. Journal of immunology 178(11) pp. 6746-6751. [Web of Science] [Pubmed]
Wilson A., Oser G.M., Jaworski M., Blanco-Bose W.E., Laurenti E., Adolphe C., Essers M.A., Macdonald H.R., Trumpp A., 2007. Dormant and self-renewing hematopoietic stem cells and their niches. Annals of the New York Academy of Sciences 1106 pp. 64-75. [DOI] [Web of Science] [Pubmed]
Zhang K.L., Mangeat B., Ortiz M., Zoete V., Trono D., Telenti A., Michielin O., 2007. Model structure of human APOBEC3G. PLoS ONE 2(4) pp. e378. [Document] [DOI] [Web of Science] [Pubmed]
Zhang S.Y., Jouanguy E., Ugolini S., Smahi A., Elain G., Romero P., Segal D., Sancho-Shimizu V., Lorenzo L., Puel A., Picard C., Chapgier A., Plancoulaine S., Titeux M., Cognet C., von Bernuth H., Ku C.L., Casrouge A., Zhang X.X., Barreiro L., Leonard J., Hamilton C., Lebon P., Héron B., Vallée L., Quintana-Murci L., Hovnanian A., Rozenberg F., Vivier E., Geissmann F., Tardieu M., Abel L., Casanova J.L., 2007. TLR3 deficiency in patients with herpes simplex encephalitis. Science 317(5844) pp. 1522-1527. [DOI] [Web of Science] [Pubmed]
Zoete V., Grosdidier A., Michielin O., 2007. Peroxisome proliferator-activated receptor structures: ligand specificity, molecular switch and interactions with regulators. Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids 1771(8) pp. 915-925. [DOI] [Web of Science] [Pubmed]
2006
Angelov G.S., Guillaume P., Cebecauer M., Bosshard G., Dojcinovic D., Baumgaertner P., Luescher I.F., 2006. Soluble MHC-peptide complexes containing long rigid linkers abolish CTL-mediated cytotoxicity. Journal of immunology 176(6) pp. 3356-3365. [Web of Science] [Pubmed]
Appay V., Jandus C., Voelter V., Reynard S., Coupland S.E., Rimoldi D., Lienard D., Guillaume P., Krieg A.M., Cerottini J.C., Romero P., Leyvraz S., Rufer N., Speiser D.E., 2006. New generation vaccine induces effective melanoma-specific CD8+ T cells in the circulation but not in the tumor site. Journal of Immunology 177(3) pp. 1670-1678. [Web of Science] [Pubmed]
Appay V., Reynard S., Voelter V., Romero P., Speiser D.E., Leyvraz S., 2006. Immuno-monitoring of CD8+ T cells in whole blood versus PBMC samples. Journal of immunological methods 309(1-2) pp. 192-9. [DOI] [Web of Science] [Pubmed]
Appay V., Speiser D.E., Rufer N., Reynard S., Barbey C., Cerottini J.C., Leyvraz S., Pinilla C., Romero P., 2006. Decreased specific CD8+ T cell cross-reactivity of antigen recognition following vaccination with Melan-A peptide. European journal of immunology 36(7) pp. 1805-14. [DOI] [Web of Science] [Pubmed]
Aublin A., Ciofani M., Willkomm N., Hamrouni A., Szymczak-Workman A.L., Takahashi T., Sandjeu Y., Guillaume P., Vignali D.A., Michielin O., Zúñiga-Pflücker J.C., Maryanski J.L., 2006. A natural structural variant of the mouse TCR beta-chain displays intrinsic receptor function and antigen specificity. Journal of immunology 177(12) pp. 8587-8594. [Web of Science] [Pubmed]
Batard P., Peterson D.A., Devêvre E., Guillaume P., Cerottini J.C., Rimoldi D., Speiser D.E., Winther L., Romero P., 2006. Dextramers: new generation of fluorescent MHC class I/peptide multimers for visualization of antigen-specific CD8+ T cells. Journal of immunological methods 310(1-2) pp. 136-148. [DOI] [Web of Science] [Pubmed]
Baumgaertner P., Rufer N., Devevre E., Derre L., Rimoldi D., Geldhof C., Voelter V., Liénard D., Romero P., Speiser D.E., 2006. Ex vivo detectable human CD8 T-cell responses to cancer-testis antigens. Cancer research 66(4) pp. 1912-6. [DOI] [Web of Science] [Pubmed]
Bianchi T., Gasser S., Trumpp A., MacDonald H.R., 2006. c-Myc acts downstream of IL-15 in the regulation of memory CD8 T-cell homeostasis. Blood 107(10) pp. 3992-3999. [DOI] [Web of Science] [Pubmed]
Bianchi T., Rufer N., MacDonald H.R., Migliaccio M., 2006. The tumor suppressor p16Ink4a regulates T lymphocyte survival. Oncogene 25(29) pp. 4110-4115. [DOI] [Web of Science] [Pubmed]
Bioley G., Jandus C., Tuyaerts S., Rimoldi D., Kwok W.W., Speiser D.E., Tiercy J.M., Thielemans K., Cerottini J.C., Romero P., 2006. Melan-A/MART-1-specific CD4 T cells in melanoma patients: identification of new epitopes and ex vivo visualization of specific T cells by MHC class II tetramers. Journal of immunology 177(10) pp. 6769-6779. [Web of Science] [Pubmed]
Capendeguy O., Chodanowski P., Michielin O., Horisberger J.D., 2006. Access of extracellular cations to their binding sites in Na,K-ATPase: role of the second extracellular loop of the alpha subunit. The Journal of general physiology 127(3) pp. 341-s52. [DOI] [Web of Science] [Pubmed]
Cesson V., Stirnemann K., Robert B., Luescher I., Filleron T., Corradin G., Mach J.P., Donda A., 2006. Active antiviral T-lymphocyte response can be redirected against tumor cells by antitumor antibody x MHC/viral peptide conjugates. Clinical cancer research 12(24) pp. 7422-7430. [DOI] [Web of Science] [Pubmed]
Chapatte L., Ayyoub M., Morel S., Peitrequin A.L., Lévy N., Servis C., Van den Eynde B.J., Valmori D., Lévy F., 2006. Processing of tumor-associated antigen by the proteasomes of dendritic cells controls in vivo T-cell responses. Cancer Research 66(10) pp. 5461-5468. [DOI] [Web of Science] [Pubmed]
Chapatte L., Colombetti S., Cerottini J. C., Levy F., 01-2006. Efficient induction of tumor antigen-specific CD8+ memory T cells by recombinant lentivectors. Cancer Research 66(2) pp. 1155-60. [DOI] [Web of Science] [Pubmed]
Chen Y.T., Iseli C., Venditti C.A., Old L.J., Simpson A.J., Jongeneel C.V., 2006. Identification of a new cancer/testis gene family, CT47, among expressed multicopy genes on the human X chromosome. Genes, Chromosomes and Cancer 45(4) pp. 392-400. [DOI] [Web of Science] [Pubmed]
Colombetti S., Fagerberg T., Baumgärtner P., Chapatte L., Speiser D.E., Rufer N., Michielin O., Lévy F., 2006. Impact of orthologous melan-A peptide immunizations on the anti-self melan-A/HLA-A2 T cell cross-reactivity. Journal of immunology 176(11) pp. 6560-6567. [Web of Science] [Pubmed]
Coudert J.D., Held W., 2006. The role of the NKG2D receptor for tumor immunity. Seminars in cancer biology 16(5) pp. 333-343. [DOI] [Web of Science] [Pubmed]
Devêvre E., Romero P., Mahnke Y.D., 2006. LiveCount Assay: concomitant measurement of cytolytic activity and phenotypic characterisation of CD8(+) T-cells by flow cytometry. Journal of immunological methods 311(1-2) pp. 31-46. [DOI] [Web of Science] [Pubmed]
Fagerberg T., Cerottini J.C., Michielin O., 2006. Structural prediction of peptides bound to MHC class I. Journal of molecular biology 356(2) pp. 521-546. [DOI] [Web of Science] [Pubmed]
Ferreira C., Furmanski A., Millrain M., Bartok I., Guillaume P., Lees R., Simpson E., MacDonald H.R., Dyson J., 2006. TCR-alpha CDR3 loop audition regulates positive selection. Journal of immunology 177(4) pp. 2477-2485. [Web of Science] [Pubmed]
Ferrero I., Mancini S.J., Grosjean F., Wilson A., Otten L., MacDonald H.R., 2006. TCRgamma silencing during alphabeta T cell development depends upon pre-TCR-induced proliferation. Journal of immunology 177(9) pp. 6038-6043. [Web of Science] [Pubmed]
Grigoriadis A., Mackay A., Reis-Filho J.S., Steele D., Iseli C., Stevenson B.J., Jongeneel C.V., Valgeirsson H., Fenwick K., Iravani M., Leao M., Simpson A.J., Strausberg R.L., Jat P.S., Ashworth A., Neville A.M., O'Hare M.J., 2006. Establishment of the epithelial-specific transcriptome of normal and malignant human breast cells based on MPSS and array expression data. Breast Cancer Research 8(5) pp. R56. [DOI] [Web of Science] [Pubmed]
Guillaume P., Baumgaertner P., Angelov G.S., Speiser D., Luescher I.F., 2006. Fluorescence-activated cell sorting and cloning of bona fide CD8+ CTL with reversible MHC-peptide and antibody Fab' conjugates. Journal of immunology 177(6) pp. 3903-3912. [Web of Science] [Pubmed]
Gumy A., Aseffa A., Rachinel N., Breton M., Otten L., Tacchini-Cottier F., Röcken M., Doyen N., Acha-Orbea H., Locksley R.M., MacDonald H.R., Launois P., Louis J., 2006. LACK-reactive CD4+ T cells require autocrine IL-2 to mediate susceptibility to Leishmania major. European Journal of Immunology 36(6) pp. 1465-1473. [DOI] [Web of Science] [Pubmed]
Huang Z., Xie H., Ioannidis V., Held W., Clevers H., Sadim M.S., Sun Z., 2006. Transcriptional regulation of CD4 gene expression by T cell factor-1/beta-catenin pathway. Journal of immunology 176(8) pp. 4880-4887. [Web of Science] [Pubmed]
Jackson H., Dimopoulos N., Mifsud N.A., Tai T.Y., Chen Q., Svobodova S., Browning J., Luescher I., Stockert L., Old L.J., Davis I.D., Cebon J., Chen W., 2006. Striking immunodominance hierarchy of naturally occurring CD8+ and CD4+ T cell responses to tumor antigen NY-ESO-1. Journal of immunology 176(10) pp. 5908-5917. [Web of Science] [Pubmed]
Jeannet G., Coudert J.D., Held W., 2006. T and B lymphocytes exert distinct effects on the homeostasis of NK cells. European journal of immunology 36(10) pp. 2725-2734. [DOI] [Web of Science] [Pubmed]
Levy F., Colombetti S., 12-2006. Promises and limitations of murine models in the development of anticancer T-cell vaccines. International Reviews of Immunology 25(5-6) pp. 269-95. [DOI] [Web of Science] [Pubmed]
Migliaccio M., Alves P.M., Romero P., Rufer N., 2006. Distinct mechanisms control human naive and antigen-experienced CD8+ T lymphocyte proliferation. Journal of immunology 176(4) pp. 2173-2182. [Web of Science] [Pubmed]
Nemir M., Croquelois A., Pedrazzini T., Radtke F., 06-2006. Induction of cardiogenesis in embryonic stem cells via downregulation of Notch1 signaling. Circulation Research 98(12) pp. 1471-8. [DOI] [Web of Science] [Pubmed]
Pittet M.J., Gati A., Le Gal F.A., Bioley G., Guillaume P., de Smedt M., Plum J., Speiser D.E., Cerottini J.C., Dietrich P.Y., Romero P., Zippelius A., 2006. Ex vivo characterization of allo-MHC-restricted T cells specific for a single MHC-peptide complex. Journal of immunology 176(4) pp. 2330-2336. [Web of Science] [Pubmed]
Radtke F., Clevers H., Riccio O., 05-2006. From gut homeostasis to cancer. Current Molecular Medicine 6(3) pp. 275-89. [Pubmed]
Retelska D., Iseli C., Bucher P., Jongeneel C.V., Naef F., 2006. Similarities and differences of polyadenylation signals in human and fly. BMC Genomics 7 p. 176. [Document] [DOI] [Web of Science] [Pubmed]
Romero P., Cerottini J.C., Speiser D.E., 2006. The human T cell response to melanoma antigens. Advances in immunology 92 pp. 187-224. [DOI] [Web of Science] [Pubmed]
Schümann J., Mycko M.P., Dellabona P., Casorati G., MacDonald H.R., 2006. Cutting edge: influence of the TCR Vbeta domain on the selection of semi-invariant NKT cells by endogenous ligands. Journal of immunology 176(4) pp. 2064-2068. [Web of Science] [Pubmed]
Speiser D.E., Baumgaertner P., Barbey C., Rubio-Godoy V., Moulin A., Corthesy P., Devevre E., Dietrich P.Y., Rimoldi D., Liénard D., Cerottini J.C., Romero P., Rufer N., 2006. A novel approach to characterize clonality and differentiation of human melanoma-specific T cell responses: spontaneous priming and efficient boosting by vaccination. Journal of immunology 177(2) pp. 1338-1348. [Web of Science] [Pubmed]
Tabiasco J., Devêvre E., Rufer N., Salaun B., Cerottini J.C., Speiser D., Romero P., 2006. Human effector CD8+ T lymphocytes express TLR3 as a functional coreceptor. Journal of immunology 177(12) pp. 8708-8713. [Web of Science] [Pubmed]
Viatte S., Alves P.M., Romero P., 2006. Reverse immunology approach for the identification of CD8 T-cell-defined antigens: advantages and hurdles. Immunology and cell biology 84(3) pp. 318-330. [DOI] [Web of Science] [Pubmed]
Walton S. M., Gerlinger M., de la Rosa O., Nuber N., Knights A., Gati A., Laumer M., Strauss L., Exner C., Schafer N., Urosevic M., Dummer R., Tiercy J. M., Mackensen A., Jaeger E., Levy F., Knuth A., Jager D., Zippelius A., 12-2006. Spontaneous CD8 T cell responses against the melanocyte differentiation antigen RAB38/NY-MEL-1 in melanoma patients. Journal of Immunology 177(11) pp. 8212-8. [Web of Science] [Pubmed]
Wang X.D., Leow C.C., Zha J., Tang Z., Modrusan Z., Radtke F., Aguet M., de Sauvage F.J., Gao W.Q., 2006. Notch signaling is required for normal prostatic epithelial cell proliferation and differentiation. Developmental Biology 290(1) pp. 66-80. [DOI] [Web of Science] [Pubmed]
Wilson A., Radtke F., 05-2006. Multiple functions of Notch signaling in self-renewing organs and cancer. FEBS Letters 580(12) pp. 2860-8. [DOI] [Pubmed]
Yip Y.L., Zoete V., Scheib H., Michielin O., 2006. Structural assessment of single amino acid mutations: application to TP53 function. Human mutation 27(9) pp. 926-937. [DOI] [Web of Science] [Pubmed]
2005
Armand F., Bucher P., Jongeneel C.V., Farmer E.E., 2005. Rapid and selective surveillance of Arabidopsis thaliana genome annotations with Centrifuge. Bioinformatics 21(12) pp. 2906-2908. [DOI] [Web of Science] [Pubmed]
Arora K., Gwinn W.M., Bower M.A., Watson A., Okwumabua I., MacDonald H.R., Bukrinsky M.I., Constant S.L., 2005. Extracellular cyclophilins contribute to the regulation of inflammatory responses. Journal of immunology 175(1) pp. 517-522. [Web of Science] [Pubmed]
Ayyoub M., Merlo A., Hesdorffer C. S., Rimoldi D., Speiser D., Cerottini J. C., Chen Y. T., Old L. J., Stevanovic S., Valmori D., 04-2005. CD4+ T cell responses to SSX-4 in melanoma patients. Journal of Immunology 174(8) pp. 5092-9. [Web of Science] [Pubmed]
Ayyoub M., Merlo A., Hesdorffer C. S., Speiser D., Rimoldi D., Cerottini J. C., Ritter G., Chen Y. T., Old L. J., Stevanovic S., Valmori D., 01-2005. Distinct but overlapping T helper epitopes in the 37-58 region of SSX-2. Clinical Immunology 114(1) pp. 70-8. [DOI] [Web of Science] [Pubmed]
Bianchi T., 2005. Role of c-Myc in homeostasis of memory CD8 T cells. 174 p., Université de Lausanne, Faculté de biologie et médecine, MacDonald H.R. (dir.).
Bricard G., Bouzourene H., Martinet O., Rimoldi D., Halkic N., Gillet M., Chaubert P., Macdonald H.R., Romero P., Cerottini J.C., Speiser D.E., 2005. Naturally acquired MAGE-A10- and SSX-2-specific CD8+ T cell responses in patients with hepatocellular carcinoma. Journal of immunology 174(3) pp. 1709-1716. [Web of Science] [Pubmed]
Cebecauer M., Guillaume P., Hozák P., Mark S., Everett H., Schneider P., Luescher I.F., 2005. Soluble MHC-peptide complexes induce rapid death of CD8+ CTL. Journal of immunology 174(11) pp. 6809-6819. [Document] [Web of Science] [Pubmed]
Cebecauer M., Guillaume P., Mark S., Michielin O., Boucheron N., Bezard M., Meyer B.H., Segura J.M., Vogel H., Luescher I.F., 2005. CD8+ cytotoxic T lymphocyte activation by soluble major histocompatibility complex-peptide dimers. The Journal of biological chemistry 280(25) pp. 23820-23828. [DOI] [Web of Science] [Pubmed]
Chapatte Delapierre L., 2005. The processing limits the presentation of the melanoma-associated antigen Melan-A in vitro and in vivo. 154 p., Université de Lausanne, Faculté de biologie et médecine, Cerottini J.-C. (dir.).
Chen Y.T., Scanlan M.J., Venditti C.A., Chua R., Theiler G., Stevenson B.J., Iseli C., Gure A.O., Vasicek T., Strausberg R.L., Jongeneel C.V., Old L.J., Simpson A.J., 2005. Identification of cancer/testis-antigen genes by massively parallel signature sequencing. Proceedings of the National Academy of Sciences of the United States of America 102(22) pp. 7940-7945. [DOI] [Web of Science] [Pubmed]
Chen Y.T., Venditti C.A., Theiler G., Stevenson B.J., Iseli C., Gure A.O., Jongeneel C.V., Old L.J., Simpson A.J., 2005. Identification of CT46/HORMAD1, an immunogenic cancer/testis antigen encoding a putative meiosis-related protein. Cancer Immunity 5 p. 9. [Pubmed]
Coudert J.D., Zimmer J., Tomasello E., Cebecauer M., Colonna M., Vivier E., Held W., 2005. Altered NKG2D function in NK cells induced by chronic exposure to NKG2D ligand-expressing tumor cells. Blood 106(5) pp. 1711-1717. [DOI] [Web of Science] [Pubmed]
Croquelois A., 2005. Inducible inactivation of Notch1 causes nodular regenerative hyperplasia in mice. 10 p., Université de Lausanne, Faculté de biologie et médecine, Radtke F. (dir.).
Croquelois A., Blindenbacher A., Terracciano L., Wang X., Langer I., Radtke F., Heim M. H., 03-2005. Inducible inactivation of Notch1 causes nodular regenerative hyperplasia in mice. Hepatology 41(3) pp. 487-96. [DOI] [Pubmed]
De Los Rios P., Cecconi F., Pretre A., Dietler G., Michielin O., Piazza F., Juanico B., 2005. Functional dynamics of PDZ binding domains: a normal-mode analysis. Biophysical journal 89(1) pp. 14-21. [DOI] [Web of Science] [Pubmed]
Deutsch S., Lyle R., Dermitzakis E.T., Attar H., Subrahmanyan L., Gehrig C., Parand L., Gagnebin M., Rougemont J., Jongeneel C.V., Antonarakis S.E., 2005. Gene expression variation and expression quantitative trait mapping of human chromosome 21 genes. Human Molecular Genetics 14(23) pp. 3741-3749. [DOI] [Web of Science] [Pubmed]
Dumortier A., Wilson A., MacDonald H.R., Radtke F., 2005. Paradigms of notch signaling in mammals. International journal of hematology 82(4) pp. 277-284. [DOI] [Web of Science] [Pubmed]
Filges I., Zaman K., Michielin O., Vulliémoz D., Perey L., Stupp R., 2005. Chimioprévention actuelle et visions futures [Present chemoprevention and future vision]. Revue médicale suisse 1(20) pp. 1343-1346, 1349. [Pubmed]
Francis J. C., Radtke F., Logan M. P., 12-2005. Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud. Developmental Dynamics 234(4) pp. 1006-15. [DOI] [Pubmed]
Gakamsky D.M., Luescher I.F., Pramanik A., Kopito R.B., Lemonnier F., Vogel H., Rigler R., Pecht I., 2005. CD8 kinetically promotes ligand binding to the T-cell antigen receptor. Biophysical journal 89(3) pp. 2121-2133. [DOI] [Web of Science] [Pubmed]
Germain C., Larbouret C., Cesson V., Donda A., Held W., Mach J.P., Pèlegrin A., Robert B., 2005. MHC class I-related chain A conjugated to antitumor antibodies can sensitize tumor cells to specific lysis by natural killer cells. Clinical Cancer Research 11(20) pp. 7516-7522. [DOI] [Web of Science] [Pubmed]
Goux D., Coudert J.D., Maurice D., Scarpellino L., Jeannet G., Piccolo S., Weston K., Huelsken J., Held W., 2005. Cooperating pre-T-cell receptor and TCF-1-dependent signals ensure thymocyte survival. Blood 106(5) pp. 1726-1733. [DOI] [Web of Science] [Pubmed]
Held W., Chalifour A., Coudert J.D., 08-2005. Regulation of natural killer cell function: a role for the NK cell's own MHC class I molecules. Medical microbiology and immunology 194(4) pp. 169-174. [DOI] [Web of Science] [Pubmed]
Jongeneel C.V., Delorenzi M., Iseli C., Zhou D., Haudenschild C.D., Khrebtukova I., Kuznetsov D., Stevenson B.J., Strausberg R.L., Simpson A.J., Vasicek T.J., 2005. An atlas of human gene expression from massively parallel signature sequencing (MPSS). Genome research 15(7) pp. 1007-14. [DOI] [Web of Science] [Pubmed]
Kuball J., Schmitz F.W., Voss R.H., Ferreira E.A., Engel R., Guillaume P., Strand S., Romero P., Huber C., Sherman L.A., Theobald M., 2005. Cooperation of human tumor-reactive CD4+ and CD8+ T cells after redirection of their specificity by a high-affinity p53A2.1-specific TCR. Immunity 22(1) pp. 117-129. [DOI] [Web of Science] [Pubmed]
Le Gal F.A., Ayyoub M., Dutoit V., Widmer V., Jäger E., Cerottini J.C., Dietrich P.Y., Valmori D., 06-2005. Distinct structural TCR repertoires in naturally occurring versus vaccine-induced CD8+ T-cell responses to the tumor-specific antigen NY-ESO-1. Journal of Immunotherapy 28(3) pp. 252-257. [DOI] [Web of Science] [Pubmed]
Levy F., Muehlethaler K., Salvi S., Peitrequin A. L., Lindholm C. K., Cerottini J. C., Rimoldi D., 04-2005. Ubiquitylation of a melanosomal protein by HECT-E3 ligases serves as sorting signal for lysosomal degradation. Molecular Biology of the Cell 16(4) pp. 1777-87. [DOI] [Web of Science] [Pubmed]
Limbourg F. P., Takeshita K., Radtke F., Bronson R. T., Chin M. T., Liao J. K., 04-2005. Essential role of endothelial Notch1 in angiogenesis. Circulation 111(14) pp. 1826-32. [DOI] [Pubmed]
MacDonald H.R., 2005. NK cell tolerance: revisiting the central dogma. Nature Immunology 6(9) pp. 868-869. [DOI] [Web of Science] [Pubmed]
MacDonald H.R., Rolink A.G, 04-2005. Lymphocyte development. Current Opinion in Immunology 17(2) pp. 97-99. [DOI] [Web of Science]
MacDonald H.R., Schümann J., 2005. The need for natural killer T cells. Nature medicine 11(3) pp. 256-257. [DOI] [Web of Science] [Pubmed]
Mahnke Y.D., Speiser D., Luescher I.F., Cerottini J.C., Romero P., 2005. Recent advances in tumour antigen-specific therapy: in vivo veritas. International journal of cancer 113(2) pp. 173-178. [DOI] [Web of Science] [Pubmed]
Mancini S.J., Mantei N., Dumortier A., Suter U., MacDonald H.R., Radtke F., 2005. Jagged1-dependent Notch signaling is dispensable for hematopoietic stem cell self-renewal and differentiation. Blood 105(6) pp. 2340-2342. [DOI] [Web of Science] [Pubmed]
Michielin O., Blanchet J.S., Fagerberg T., Valmori D., Rubio-Godoy V., Speiser D., Ayyoub M., Alves P., Luescher I., Gairin J.E., Cerottini J.C., Romero P., 2005. Tinkering with nature: the tale of optimizing peptide based cancer vaccines. Cancer treatment and research 123 pp. 267-291. [Pubmed]
Montes M., Rufer N., Appay V., Reynard S., Pittet M.J., Speiser D.E., Guillaume P., Cerottini J.C., Romero P., Leyvraz S., 2005. Optimum in vitro expansion of human antigen-specific CD8 T cells for adoptive transfer therapy. Clinical and experimental immunology 142(2) pp. 292-302. [DOI] [Web of Science] [Pubmed]
Murphy M.J., Wilson A., Trumpp A, 2005. More than just proliferation: Myc function in stem cells. Trends Cell Biol. 15 pp. 128-137.
Nyfeler Y., Kirch R. D., Mantei N., Leone D. P., Radtke F., Suter U., Taylor V., 10-2005. Jagged1 signals in the postnatal subventricular zone are required for neural stem cell self-renewal. EMBO Journal 24(19) pp. 3504-15. [DOI] [Pubmed]
Radtke F., Clevers H., 03-2005. Self-renewal and cancer of the gut: two sides of a coin. Science 307(5717) pp. 1904-9. [DOI] [Pubmed]
Radtke F., Schweisguth F., Pear W., 12-2005. The Notch 'gospel'. EMBO Reports 6(12) pp. 1120-5. [DOI] [Pubmed]
Radtke F., Wilson A., MacDonald H.R., 2005. Notch signaling in hematopoiesis and lymphopoiesis: lessons from Drosophila. BioEssays 27(11) pp. 1117-1128. [DOI] [Web of Science] [Pubmed]
Romero P., Cerottini J.C., Luescher I., 2005. On the significance of CD8 alpha alpha expression for T cell memory. European journal of immunology 35(11) pp. 3092-3094. [DOI] [Web of Science] [Pubmed]
Rufer N., Reichenbach P., Romero P., 2005. Methods for the ex vivo characterization of human CD8+ T subsets based on gene expression and replicative history analysis. Methods in molecular medicine 109 pp. 265-84. [Pubmed]
Saleh F., Renno W., Klepacek I., Ibrahim G., Asfar S., Dashti H., Abdeen S., Romero P., Dashti A., Behbehani A, 2005. Melanoma Immunotherapy: Past, Present and Future. Curr. Pharm. Design 11 pp. 3461-3473.
Schümann J., Pittoni P., Tonti E., Macdonald H.R., Dellabona P., Casorati G., 2005. Targeted expression of human CD1d in transgenic mice reveals independent roles for thymocytes and thymic APCs in positive and negative selection of Valpha14i NKT cells. Journal of Immunology 175(11) pp. 7303-7310. [Web of Science] [Pubmed]
Schwarz K., Meijerink E., Speiser D. E., Tissot A. C., Cielens I., Renhof R., Dishlers A., Pumpens P., Bachmann M. F., 03-2005. Efficient homologous prime-boost strategies for T cell vaccination based on virus-like particles. European Journal of Immunology 35(3) pp. 816-21. [DOI] [Web of Science] [Pubmed]
Slingluff C.L., Speiser D.E., 04-2005. Progress and controversies in developing cancer vaccines. Journal of Translational Medicine 3(1) p. 18. [DOI] [Pubmed]
Speiser D. E., 08-2005. Immunological techniques: ex vivo characterization of T cell-mediated immune responses in cancer. Current Opinion in Immunology 17(4) pp. 419-22. [DOI] [Web of Science] [Pubmed]
Speiser D.E., Cerottini J.C., Romero P., 2005. Tumor cell recognition efficiency by T cells. PLoS medicine 2(3) pp. e77; author reply e95. [Document] [DOI] [Web of Science] [Pubmed]
Speiser D.E., Liénard D., Rufer N., Rubio-Godoy V., Rimoldi D., Lejeune F., Krieg A.M., Cerottini J.C., Romero P., 2005. Rapid and strong human CD8+ T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909. Journal of Clinical Investigation 115(3) pp. 739-746. [DOI] [Web of Science] [Pubmed]
Speiser D.E., Romero P., 2005. Toward improved immunocompetence of adoptively transferred CD8+ T cells. Journal of Clinical Investigation 115(6) pp. 1467-1469. [DOI] [Web of Science] [Pubmed]
Suarez M., Haenni M., Canarelli S., Fisch F., Chodanowski P., Servis C., Michielin O., Freitag R., Moreillon P., Mermod N., 2005. Structure-function characterization and optimization of a plant-derived antibacterial peptide. Antimicrobial Agents and Chemotherapy 49(9) pp. 3847-3857. [DOI] [Web of Science] [Pubmed]
van Baren N., Bonnet M.C., Dréno B., Khammari A., Dorval T., Piperno-Neumann S., Liénard D., Speiser D., Marchand M., Brichard V.G., Escudier B., Négrier S., Dietrich P.Y., Maraninchi D., Osanto S., Meyer R.G., Ritter G., Moingeon P., Tartaglia J., van der Bruggen P., Coulie P.G., Boon T., 12-2005. Tumoral and immunologic response after vaccination of melanoma patients with an ALVAC virus encoding MAGE antigens recognized by T cells. Journal of Clinical Oncology 23(35) pp. 9008-9021. [DOI] [Web of Science] [Pubmed]
van Es J. H., van Gijn M. E., Riccio O., van den Born M., Vooijs M., Begthel H., Cozijnsen M., Robine S., Winton D. J., Radtke F., Clevers H., 06-2005. Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells. Nature 435(7044) pp. 959-63. [DOI] [Pubmed]
van Houdt I.S., Oudejans J.J., van den Eertwegh A.J., Baars A., Vos W., Bladergroen B.A., Rimoldi D., Muris J.J., Hooijberg E., Gundy C.M., Meijer C.J., Kummer J.A., 2005. Expression of the apoptosis inhibitor protease inhibitor 9 predicts clinical outcome in vaccinated patients with stage III and IV melanoma. Clinical Cancer Research 11(17) pp. 6400-6407. [DOI] [Pubmed]
Vauclair S., Nicolas M., Barrandon Y., Radtke F., 08-2005. Notch1 is essential for postnatal hair follicle development and homeostasis. Developmental Biology 284(1) pp. 184-93. [DOI] [Web of Science] [Pubmed]
Viatte S., 2005. Identification of new MHC class I-restricted human tumor antigens for immunotherapy. 197 p., Université de Lausanne, Faculté de biologie et médecine, Cerottini J.-C. (dir.).
Walter S., Bioley G., Bühring H.J., Koch S., Wernet D., Zippelius A., Pawelec G., Romero P., Stevanović S., Rammensee H.G., Gouttefangeas C., 2005. High frequencies of functionally impaired cytokeratin 18-specific CD8+ T cells in healthy HLA-A2+ donors. European Journal of Immunology 35(10) pp. 2876-2885. [DOI] [Web of Science] [Pubmed]
2004
Ayyoub M., Hesdorffer C. S., Metthez G., Stevanovic S., Ritter G., Chen Y. T., Old L. J., Speiser D., Cerottini J. C., Valmori D., 06-2004. Identification of an SSX-2 epitope presented by dendritic cells to circulating autologous CD4+ T cells. Journal of Immunology 172(11) pp. 7206-11. [Web of Science] [Pubmed]
Ayyoub M., Hesdorffer C. S., Montes M., Merlo A., Speiser D., Rimoldi D., Cerottini J. C., Ritter G., Scanlan M., Old L. J., Valmori D., 04-2004. An immunodominant SSX-2-derived epitope recognized by CD4+ T cells in association with HLA-DR. Journal of Clinical Investigation 113(8) pp. 1225-33. [DOI] [Web of Science] [Pubmed]
Chapatte L., Servis C., Valmori D., Burlet-Schiltz O., Dayer J., Monsarrat B., Romero P., Lévy F., 2004. Final antigenic Melan-A peptides produced directly by the proteasomes are preferentially selected for presentation by HLA-A*0201 in melanoma cells. Journal of Immunology 173(10) pp. 6033-6040. [Web of Science] [Pubmed]
Cobas M., Wilson A., Ernst B., Mancini S.J., MacDonald H.R., Kemler R., Radtke F., 2004. Beta-catenin is dispensable for hematopoiesis and lymphopoiesis. The Journal of experimental medicine 199(2) pp. 221-229. [DOI] [Web of Science] [Pubmed]
Didierlaurent A., Ferrero I., Otten L.A., Dubois B., Reinhardt M., Carlsen H., Blomhoff R., Akira S., Kraehenbuhl J.P., Sirard J.C., 2004. Flagellin promotes myeloid differentiation factor 88-dependent development of Th2-type response. Journal of Immunology 172(11) pp. 6922-6930. [Web of Science] [Pubmed]
Doucey M.A., Scarpellino L., Zimmer J., Guillaume P., Luescher I.F., Bron C., Held W., 2004. Cis association of Ly49A with MHC class I restricts natural killer cell inhibition. Nature Immunology 5(3) pp. 328-336. [DOI] [Web of Science] [Pubmed]
Gakamsky D.M., Luescher I.F., Pecht I., 2004. T cell receptor-ligand interactions: a conformational preequilibrium or an induced fit. Proceedings of the National Academy of Sciences of the United States of America 101(24) pp. 9063-9066. [DOI] [Web of Science] [Pubmed]
Godfrey D.I., MacDonald H.R., Kronenberg M., Smyth M.J., Van Kaer L., 2004. NKT cells: what's in a name? Nature reviews. Immunology 4(3) pp. 231-237. [DOI] [Web of Science] [Pubmed]
Goux D., 2004. Role of the transcription factor T cell factor-1 (TCF-1) for T cell development. 103 p., Université de Lausanne, Faculté de biologie et médecine, Held W. (dir.).
Gross D.A., Graff-Dubois S., Opolon P., Cornet S., Alves P., Bennaceur-Griscelli A., Faure O., Guillaume P., Firat H., Chouaib S., Lemonnier F.A., Davoust J., Miconnet I., Vonderheide R.H., Kosmatopoulos K., 2004. High vaccination efficiency of low-affinity epitopes in antitumor immunotherapy. Journal of Clinical Investigation 113(3) pp. 425-433. [DOI] [Pubmed]
Hauert J., Fernandez-Carneado J., Michielin O., Mathieu S., Grell D., Schapira M., Spertini O., Mutter M., Tuchscherer G., Kovacsovics T., 2004. A template-assembled synthetic protein surface mimetic of the von Willebrand factor A1 domain inhibits botrocetin-induced platelet aggregation. Chembiochem 5(6) pp. 856-864. [DOI] [Web of Science] [Pubmed]
Hoflinger S., Kesavan K., Fuxa M., Hutter C., Heavey B., Radtke F., Busslinger M., 09-2004. Analysis of Notch1 function by in vitro T cell differentiation of Pax5 mutant lymphoid progenitors. Journal of Immunology 173(6) pp. 3935-44. [Pubmed]
Horisberger J.D., Kharoubi-Hess S., Guennoun S., Michielin O., 2004. The fourth transmembrane segment of the Na,K-ATPase alpha subunit: a systematic mutagenesis study. The Journal of biological chemistry 279(28) pp. 29542-50. [DOI] [Web of Science] [Pubmed]
Lee S.Y., Williamson B., Caballero O.L., Chen Y.T., Scanlan M.J., Ritter G., Jongeneel C.V., Simpson A.J., Old L.J., 2004. Identification of the gonad-specific anion transporter SLCO6A1 as a cancer/testis (CT) antigen expressed in human lung cancer. Cancer Immunity 4 p. 13. [Pubmed]
Lejeune F.J, Matter M, Guggisberg D, Cerottini J.P., Liénard D, 2004. Prise en charge du mélanome malin cutané au stade de tumeur primaire. Médecine et Hygiène 62(2504) pp. 2256-2263.
Li C., Grosdidier A., Crambert G., Horisberger J.D., Michielin O., Geering K., 2004. Structural and functional interaction sites between Na,K-ATPase and FXYD proteins. The Journal of biological chemistry 279(37) pp. 38895-902. [DOI] [Web of Science] [Pubmed]
Liénard D., Rimoldi D., Marchand M., Dietrich P.Y., van Baren N., Geldhof C., Batard P., Guillaume P., Ayyoub M., Pittet M.J., Zippelius A., Fleischhauer K., Lejeune F., Cerottini J.C., Romero P., Speiser D.E., 2004. Ex vivo detectable activation of Melan-A-specific T cells correlating with inflammatory skin reactions in melanoma patients vaccinated with peptides in IFA. Cancer Immunity 4 p. 4. [Pubmed]
Meidenbauer N., Zippelius A., Pittet M.J., Laumer M., Vogl S., Heymann J., Rehli M., Seliger B., Schwarz S., Le Gal F.A., Dietrich P.Y., Andreesen R., Romero P., Mackensen A., 2004. High frequency of functionally active Melan-a-specific T cells in a patient with progressive immunoproteasome-deficient melanoma. Cancer Research 64(17) pp. 6319-6326. [DOI] [Web of Science] [Pubmed]
Meijer S.L., Dols A., Hu H.M., Chu Y., Romero P., Urba W.J., Fox B.A., 2004. Reduced L-selectin (CD62LLow) expression identifies tumor-specific type 1 T cells from lymph nodes draining an autologous tumor cell vaccine. Cellular Immunology 227(2) pp. 93-102. [DOI] [Web of Science] [Pubmed]
Michielin O., Udry E., Périard D., Matzinger O., Lobrinus J.A., Stupp R., 2004. Irinotecan-induced interstitial pneumonia. The lancet oncology 5(5) pp. 322-4. [DOI] [Web of Science] [Pubmed]
Movassagh M., Spatz A., Davoust J., Lebecque S., Romero P., Pittet M., Rimoldi D., Liénard D., Gugerli O., Ferradini L., Robert C., Avril M.F., Zitvogel L., Angevin E., 2004. Selective accumulation of mature DC-Lamp+ dendritic cells in tumor sites is associated with efficient T-cell-mediated antitumor response and control of metastatic dissemination in melanoma. Cancer Research 64(6) pp. 2192-2198. [DOI] [Web of Science] [Pubmed]
Nagorsen D., Servis C., Lévy N., Provenzano M., Dudley M.E., Marincola F.M., Lévy F., 2004. Proteasomal cleavage does not determine immunogenicity of gp100-derived peptides gp100 209-217 and gp100 209-217T210M. Cancer Immunology, Immunotherapy 53(9) pp. 817-824. [DOI] [Web of Science] [Pubmed]
Pagni M., Ioannidis V., Cerutti L., Zahn-Zabal M., Jongeneel C.V., Falquet L., 2004. MyHits: a new interactive resource for protein annotation and domain identification. Nucleic Acids Research 32(Web Server issue) pp. W332-W335. [DOI] [Web of Science] [Pubmed]
Radtke F., Wilson A., MacDonald H.R., 2004. Notch signaling in T- and B-cell development. Current opinion in immunology 16(2) pp. 174-179. [DOI] [Web of Science] [Pubmed]
Radtke F., Wilson A., Mancini S.J., MacDonald H.R., 2004. Notch regulation of lymphocyte development and function. Nature immunology 5(3) pp. 247-253. [DOI] [Web of Science] [Pubmed]
Romero P., Cerottini J.C., Speiser D.E., 2004. Monitoring tumor antigen specific T-cell responses in cancer patients and phase I clinical trials of peptide-based vaccination. Cancer Immunology, Immunotherapy 53(3) pp. 249-255. [DOI] [Web of Science] [Pubmed]
Rothenfusser S., Hornung V., Ayyoub M., Britsch S., Towarowski A., Krug A., Sarris A., Lubenow N., Speiser D., Endres S., Hartmann G., 03-2004. CpG-A and CpG-B oligonucleotides differentially enhance human peptide-specific primary and memory CD8+ T-cell responses in vitro. Blood 103(6) pp. 2162-9. [DOI] [Web of Science] [Pubmed]
Speiser D.E., Pittet M.J., Guillaume P., Lubenow N., Hoffman E., Cerottini J.C., Romero P., 2004. Ex vivo analysis of human antigen-specific CD8+ T-cell responses: quality assessment of fluorescent HLA-A2 multimer and interferon-gamma ELISPOT assays for patient immune monitoring. Journal of Immunotherapy 27(4) pp. 298-308. [DOI] [Web of Science] [Pubmed]
Sperisen P., Iseli C., Pagni M., Stevenson B.J., Bucher P., Jongeneel C.V., 2004. trome, trEST and trGEN: databases of predicted protein sequences. Nucleic Acids Research 32(Database issue) pp. D509-D511. [DOI] [Web of Science] [Pubmed]
Stauffer Y., Theiler G., Sperisen P., Lebedev Y., Jongeneel C.V., 2004. Digital expression profiles of human endogenous retroviral families in normal and cancerous tissues. Cancer Immunity 4 p. 2. [Pubmed]
Tacchini-Cottier F., Allenbach C., Otten L.A., Radtke F., 2004. Notch1 expression on T cells is not required for CD4+ T helper differentiation. European Journal of Immunology 34(6) pp. 1588-1596. [DOI] [Web of Science] [Pubmed]
Tardivel A., Tinel A., Lens S., Steiner Q.G., Sauberli E., Wilson A., Mackay F., Rolink A.G., Beermann F., Tschopp J., Schneider P, 2004. The anti-apoptotic factor Bcl-2 can functionally substitute for the B cell survival but not for the marginal zone B cell differentiation activity of BAFF. European Journal of Immunology 34 pp. 509-518.
Tardivel A., Tinel A., Lens S., Steiner Q.G., Sauberli E., Wilson A., Mackay F., Rolink A.G., Beermann F., Tschopp J., Schneider P., 2004. The anti-apoptotic factor Bcl-2 can functionally substitute for the B cell survival but not for the marginal zone B cell differentiation activity of BAFF. European Journal of Immunology 34(2) pp. 509-518. [Document] [DOI] [Web of Science] [Pubmed]
Teixeiro E., Daniels M.A., Hausmann B., Schrum A.G., Naeher D., Luescher I., Thome M., Bragado R., Palmer E., 2004. T cell division and death are segregated by mutation of TCRbeta chain constant domains. Immunity 21(4) pp. 515-526. [DOI] [Web of Science] [Pubmed]
Walker E.B., Haley D., Miller W., Floyd K., Wisner K.P., Sanjuan N., Maecker H., Romero P., Hu H.M., Alvord W.G., Smith J.W., Fox B.A., Urba W.J., 2004. gp100(209-2M) peptide immunization of human lymphocyte antigen-A2+ stage I-III melanoma patients induces significant increase in antigen-specific effector and long-term memory CD8+ T cells. Clinical Cancer Research 10(2) pp. 668-680. [DOI] [Web of Science] [Pubmed]
Wilson A., Murphy M.J., Oskarsson T., Kaloulis K., Bettess M.D., Oser G.M., Pasche A.C., Knabenhans C., Macdonald H.R., Trumpp A., 2004. c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation. Genes and development 18(22) pp. 2747-2763. [DOI] [Web of Science] [Pubmed]
Wilson, A., Murphy, M.J., Oskarsson, T., Kaloulis, K., Bettess, M.D., Oser, G.M., Pasche, A.-C., Knabenhans, C., MacDonald, H.R., Trumpp, A, 2004. c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation. Genes Dev. 18 pp. 2747-2763.
Yoon K., Nery S., Rutlin M. L., Radtke F., Fishell G., Gaiano N., 10-2004. Fibroblast growth factor receptor signaling promotes radial glial identity and interacts with Notch1 signaling in telencephalic progenitors. Journal of Neuroscience 24(43) pp. 9497-506. [DOI] [Pubmed]
Zippelius A., Batard P., Rubio-Godoy V., Bioley G., Liénard D., Lejeune F., Rimoldi D., Guillaume P., Meidenbauer N., Mackensen A., Rufer N., Lubenow N., Speiser D., Cerottini J.C., Romero P., Pittet M.J., 2004. Effector function of human tumor-specific CD8 T cells in melanoma lesions: a state of local functional tolerance. Cancer research 64(8) pp. 2865-73. [DOI] [Web of Science] [Pubmed]
Zippelius A., Bioley G., Le Gal F.A., Rufer N., Brandes M., Batard P., De Smedt M., Plum J., Speiser D.E., Cerottini J.C., Dietrich P.Y., Romero P., Pittet M.J., 2004. Human thymus exports naive CD8 T cells that can home to nonlymphoid tissues. Journal of Immunology 172(5) pp. 2773-2777. [Web of Science] [Pubmed]
2003
Ayyoub M., Rimoldi D., Guillaume P., Romero P., Cerottini J.C., Valmori D., Speiser D., 2003. Tumor-reactive, SSX-2-specific CD8+ T cells are selectively expanded during immune responses to antigen-expressing tumors in melanoma patients. Cancer Research 63(17) pp. 5601-5606. [Web of Science] [Pubmed]
Ayyoub M., Zippelius A., Pittet M.J., Rimoldi D., Valmori D., Cerottini J.C., Romero P., Lejeune F., Liénard D., Speiser D.E., 2003. Activation of human melanoma reactive CD8+ T cells by vaccination with an immunogenic peptide analog derived from Melan-A/melanoma antigen recognized by T cells-1. Clinical Cancer Research 9(2) pp. 669-677. [Web of Science] [Pubmed]
Bernimoulin M.P., Zeng X.L., Abbal C., Giraud S., Martinez M., Michielin O., Schapira M., Spertini O., 2003. Molecular basis of leukocyte rolling on PSGL-1. Predominant role of core-2 O-glycans and of tyrosine sulfate residue 51. The Journal of biological chemistry 278(1) pp. 37-47. [DOI] [Web of Science] [Pubmed]
Brentani H., Caballero O.L., Camargo A.A., da Silva A.M., da Silva W.A., Dias Neto E., Grivet M., Gruber A., Guimaraes P.E., Hide W., Iseli C., Jongeneel C.V., Kelso J., Nagai M.A., Ojopi E.P., Osorio E.C., Reis E.M., Riggins G.J., Simpson A.J., de Souza S., Stevenson B.J., Strausberg R.L., Tajara E.H., Verjovski-Almeida S., Acencio M.L., Bengtson M.H., Bettoni F., Bodmer W.F., Briones M.R., Camargo L.P., Cavenee W., Cerutti J.M., Coelho Andrade L.E., Costa dos Santos P.C., Ramos Costa M.C., da Silva I.T., Estécio M.R., Sa Ferreira K., Furnari F.B., Faria M., Galante P.A., Guimaraes G.S., Holanda A.J., Kimura E.T., Leerkes M.R., Lu X., Maciel R.M., Martins E.A., Massirer K.B., Melo A.S., Mestriner C.A., Miracca E.C., Miranda L.L., Nobrega F.G., Oliveira P.S., Paquola A.C., Pandolfi J.R., Campos Pardini M.I., Passetti F., Quackenbush J., Schnabel B., Sogayar M.C., Souza J.E., Valentini S.R., Zaiats A.C., Amaral E.J., Arnaldi L.A., de Araújo A.G., de Bessa S.A., Bicknell D.C., Ribeiro de Camaro M.E., Carraro D.M., Carrer H., Carvalho A.F., Colin C., Costa F., Curcio C., Guerreiro da Silva I.D., Pereira da Silva N., Dellamano M., El-Dorry H., Espreafico E.M., Scattone Ferreira A.J., Ayres Ferreira C., Fortes M.A., Gama A.H., Giannella-Neto D., Giannella M.L., Giorgi R.R., Goldman G.H., Goldman M.H., Hackel C., Ho P.L., Kimura E.M., Kowalski L.P., Krieger J.E., Leite L.C., Lopes A., Luna A.M., Mackay A., Mari S.K., Marques A.A., Martins W.K., Montagnini A., Mourão Neto M., Nascimento A.L., Neville A.M., Nobrega M.P., O'Hare M.J., Otsuka A.Y., Ruas de Melo A.I., Paco-Larson M.L., Guimarães Pereira G., Pereira da Silva N., Pesquero J.B., Pessoa J.G., Rahal P., Rainho C.A., Rodrigues V., Rogatto S.R., Romano C.M., Romeiro J.G., Rossi B.M., Rusticci M., Guerra de Sá R., Sant' Anna S.C., Sarmazo M.L., Silva T.C., Soares F.A., Sonati Mde F, de Freitas Sousa J., Queiroz D., Valente V., Vettore A.L., Villanova F.E., Zago M.A., Zalcberg H., Human Cancer Genome Project/Cancer Genome Anatomy Project Annotation Consortium, Human Cancer Genome Project Sequencing Consortium, 2003. The generation and utilization of a cancer-oriented representation of the human transcriptome by using expressed sequence tags. Proceedings of the National Academy of Sciences of the United States of America 100(23) pp. 13418-13423. [DOI] [Web of Science] [Pubmed]
Capone M., Cantarella D., Schümann J., Naidenko O.V., Garavaglia C., Beermann F., Kronenberg M., Dellabona P., MacDonald H.R., Casorati G., 2003. Human invariant V alpha 24-J alpha Q TCR supports the development of CD1d-dependent NK1.1+ and NK1.1- T cells in transgenic mice. Journal of immunology 170(5) pp. 2390-2398. [Web of Science] [Pubmed]
Capone M., Lees R.K., Finke D., Ernst B., Meerwijk J.P., MacDonald H.R., 2003. Selective absence of CD8+ TCRalpha beta+ intestinal epithelial cells in transgenic mice expressing beta2-microglobulin-associated ligands exclusively on thymic cortical epithelium. European Journal of Immunology 33(6) pp. 1471-1477. [DOI] [Web of Science] [Pubmed]
Corcoran L., Ferrero I., Vremec D., Lucas K., Waithman J., O'Keeffe M., Wu L., Wilson A., Shortman K., 2003. The lymphoid past of mouse plasmacytoid cells and thymic dendritic cells. Journal of Immunology 170(10) pp. 4926-4932. [Pubmed]
Dietrich P.Y., Le Gal F.A., Dutoit V., Pittet M.J., Trautman L., Zippelius A., Cognet I., Widmer V., Walker P.R., Michielin O., Guillaume P., Connerotte T., Jotereau F., Coulie P.G., Romero P., Cerottini J.C., Bonneville M., Valmori D., 2003. Prevalent role of TCR alpha-chain in the selection of the preimmune repertoire specific for a human tumor-associated self-antigen. Journal of Immunology 170(10) pp. 5103-5109. [Web of Science] [Pubmed]
Doucey M.A., Goffin L., Naeher D., Michielin O., Baumgärtner P., Guillaume P., Palmer E., Luescher I.F., 2003. CD3 delta establishes a functional link between the T cell receptor and CD8. Journal of Biological Chemistry 278(5) pp. 3257-3264. [DOI] [Web of Science] [Pubmed]
Doucey M.A., Legler D.F., Faroudi M., Boucheron N., Baumgaertner P., Naeher D., Cebecauer M., Hudrisier D., Rüegg C., Palmer E., Valitutti S., Bron C., Luescher I.F., 2003. The beta1 and beta3 integrins promote T cell receptor-mediated cytotoxic T lymphocyte activation. Journal of Biological Chemistry 278(29) pp. 26983-26991. [DOI] [Web of Science] [Pubmed]
Dutoit V., Guillaume P., Ayyoub M., Hesdorffer C.S., Luescher I.F., Valmori D., 2003. Decreased binding of peptides-MHC class I (pMHC) multimeric complexes to CD8 affects their binding avidity for the TCR but does not significantly impact on pMHC/TCR dissociation rate. Journal of immunology 170(10) pp. 5110-5117. [Web of Science] [Pubmed]
Esslinger C., Chapatte L., Finke D., Miconnet I., Guillaume P., Lévy F., MacDonald H.R., 2003. In vivo administration of a lentiviral vaccine targets DCs and induces efficient CD8(+) T cell responses. The Journal of clinical investigation 111(11) pp. 1673-1681. [DOI] [Web of Science] [Pubmed]
Falquet L., Bordoli L., Ioannidis V., Pagni M., Jongeneel C.V., 2003. Swiss EMBnet node web server. Nucleic Acids Research 31(13) pp. 3782-3783. [DOI] [Web of Science] [Pubmed]
Favre M., Butticaz C., Stevenson B., Jongeneel C.V., Telenti A., 2003. High frequency of alternative splicing of human genes participating in the HIV-1 life cycle: a model using TSG101, betaTrCP, PPIA, INI1, NAF1, and PML. Journal of Acquired Immune Deficiency Syndromes 34(2) pp. 127-133. [DOI] [Web of Science] [Pubmed]
Finke D., Luther S.A., Acha-Orbea H., 2003. The role of neutralizing antibodies for mouse mammary tumor virus transmission and mammary cancer development. Proceedings of the National Academy of Sciences of the United States of America 100(1) pp. 199-204. [DOI] [Pubmed]
Finke D., Luther S.A., Acha-Orbea H., 2003. The role of neutralizing antibodies for mouse mammary tumor virus transmission and mammary cancer development. Proceedings of the National Academy of Sciences of the United States of America 100(1) pp. 199-204. [DOI] [Web of Science] [Pubmed]
Guillaume P., Legler D.F., Boucheron N., Doucey M.A., Cerottini J.C., Luescher I.F., 2003. Soluble major histocompatibility complex-peptide octamers with impaired CD8 binding selectively induce Fas-dependent apoptosis. Journal of Biological Chemistry 278(7) pp. 4500-4509. [DOI] [Web of Science] [Pubmed]
Held W., Coudert J.D., Zimmer J., 04-2003. The NK cell receptor repertoire: formation, adaptation and exploitation. Current opinion in immunology 15(2) pp. 233-237. [DOI] [Web of Science] [Pubmed]
Ioannidis V., Kunz B., Tanamachi D.M., Scarpellino L., Held W., 2003. Initiation and limitation of Ly-49A NK cell receptor acquisition by T cell factor-1. Journal of immunology 171(2) pp. 769-775. [Web of Science] [Pubmed]
Jongeneel C.V., Iseli C., Stevenson B.J., Riggins G.J., Lal A., Mackay A., Harris R.A., O'Hare M.J., Neville A.M., Simpson A.J., Strausberg R.L., 2003. Comprehensive sampling of gene expression in human cell lines with massively parallel signature sequencing. Proceedings of the National Academy of Sciences of the United States of America 100(8) pp. 4702-4705. [DOI] [Web of Science] [Pubmed]
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Matter M., Lejeune F., Antonescu C., Bischof Delaloye A., Gugerli O., Lobrinus A., Cerottini J. P., Guggisberg D., Liénard D., 2003. Revue du traitement chirurgical du mélanome malin. Médecine et Hygiène 61(2438) pp. 1088-1097.
Mpandi M., Otten L.A., Lavanchy C., Acha-Orbea H., Finke D., 2003. Passive immunization with neutralizing antibodies interrupts the mouse mammary tumor virus life cycle. Journal of virology 77(17) pp. 9369-77. [DOI] [Web of Science] [Pubmed]
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Pittet M.J., Rubio-Godoy V., Bioley G., Guillaume P., Batard P., Speiser D., Luescher I., Cerottini J.C., Romero P., Zippelius A., 2003. Alpha 3 domain mutants of peptide/MHC class I multimers allow the selective isolation of high avidity tumor-reactive CD8 T cells. Journal of immunology 171(4) pp. 1844-1849. [Web of Science] [Pubmed]
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Rimoldi D, Cerottini J.C, Romero P, 2003. Fas/Fas ligand and tumor immunity. pp. 213-235 in Ochoa A.C. (eds.) Mechanisms of tumor escape from the immune response. The tumor immunology and immunotherapy series 2. Taylor & Francis, London.
Rimoldi D., Lemoine R., Kurt A.M., Salvi S., Berset M., Matter M., Roche B., Cerottini J.P., Guggisberg D., Krischer J., Braun R., Willi J.P., Antonescu C., Slosman D., Lejeune F.J., Liénard D., 2003. Detection of micrometastases in sentinel lymph nodes from melanoma patients: direct comparison of multimarker molecular and immunopathological methods. Melanoma research 13(5) pp. 511-20. [DOI] [Web of Science] [Pubmed]
Rimoldi D., Salvi S., Lienard D., Lejeune F. J., Speiser D., Zografos L., Cerottini J. C., 09-2003. Lack of BRAF mutations in uveal melanoma. Cancer Research 63(18) pp. 5712-5. [Web of Science] [Pubmed]
Rufer N., Zippelius A., Batard P., Pittet M.J., Kurth I., Corthesy P., Cerottini J.C., Leyvraz S., Roosnek E., Nabholz M., Romero P., 2003. Ex vivo characterization of human CD8+ T subsets with distinct replicative history and partial effector functions. Blood 102(5) pp. 1779-87. [DOI] [Web of Science] [Pubmed]
Sauce D., Rufer N., Mercier P., Bodinier M., Rémy-Martin J.P., Duperrier A., Ferrand C., Hervé P., Romero P., Lang F., Tiberghien P., Robinet E., 2003. Retrovirus-mediated gene transfer in polyclonal T cells results in lower apoptosis and enhanced ex vivo cell expansion of CMV-reactive CD8 T cells as compared with EBV-reactive CD8 T cells. Blood 102(4) pp. 1241-8. [DOI] [Web of Science] [Pubmed]
Schümann J., Voyle R.B., Wei B.Y., MacDonald H.R., 2003. Cutting edge: influence of the TCR V beta domain on the avidity of CD1d:alpha-galactosylceramide binding by invariant V alpha 14 NKT cells. Journal of immunology 170(12) pp. 5815-5819. [Web of Science] [Pubmed]
Schwitzgebel V.M., Mamin A., Brun T., Ritz-Laser B., Zaiko M., Maret A., Jornayvaz F.R., Theintz G.E., Michielin O., Melloul D., Philippe J., 2003. Agenesis of human pancreas due to decreased half-life of insulin promoter factor 1. The Journal of clinical endocrinology and metabolism 88(9) pp. 4398-406. [DOI] [Web of Science] [Pubmed]
Silva A.P., Salim A.C., Bulgarelli A., de Souza J.E., Osorio E., Caballero O.L., Iseli C., Stevenson B.J., Jongeneel C.V., de Souza S.J., Simpson A.J., Camargo A.A., 2003. Identification of 9 novel transcripts and two RGSL genes within the hereditary prostate cancer region (HPC1) at 1q25. Gene 310 pp. 49-57. [DOI] [Web of Science] [Pubmed]
Smith J.W., Walker E.B., Fox B.A., Haley D., Wisner K.P., Doran T., Fisher B., Justice L., Wood W., Vetto J., Maecker H., Dols A., Meijer S., Hu H.M., Romero P., Alvord W.G., Urba W.J., 2003. Adjuvant immunization of HLA-A2-positive melanoma patients with a modified gp100 peptide induces peptide-specific CD8+ T-cell responses. Journal of Clinical Oncology 21(8) pp. 1562-1573. [DOI] [Pubmed]
Speiser D. E., Zippelius A., 01-2003. Endotoxin and asthma. New England Journal of Medicine 348(2) pp. 171-4; author reply 171-4. [Pubmed]
Speiser D.E., Pittet M.J., Rimoldi D., Guillaume P., Luescher I.F., Liénard D., Lejeune F., Cerottini J.C., Romero P., 2003. Evaluation of melanoma vaccines with molecularly defined antigens by ex vivo monitoring of tumor-specific T cells. Seminars in cancer biology 13(6) pp. 461-72. [DOI] [Web of Science] [Pubmed]
Speiser D.E., Rimoldi D., Batard P., Liénard D., Lejeune F., Cerottini J.C., Romero P., 2003. Disease-driven T cell activation predicts immune responses to vaccination against melanoma. Cancer Immunity 3 p. 12. [Pubmed]
Stevenson B.J., Iseli C., Beutler B., Jongeneel C.V., 2003. Use of transcriptome data to unravel the fine structure of genes involved in sepsis. Journal of Infectious Diseases 187(Suppl. 2) pp. S308-S314. [DOI] [Web of Science] [Pubmed]
Valmori D., Dutoit V., Ayyoub M., Rimoldi D., Guillaume P., Liénard D., Lejeune F., Cerottini J.C., Romero P., Speiser D.E., 2003. Simultaneous CD8+ T cell responses to multiple tumor antigen epitopes in a multipeptide melanoma vaccine. Cancer immunity : a journal of the Academy of Cancer Immunology 3 p. 15. [Pubmed]
Voyle R.B., Beermann F., Lees R.K., Schümann J., Zimmer J., Held W., MacDonald H.R., 2003. Ligand-dependent inhibition of CD1d-restricted NKT cell development in mice transgenic for the activating receptor Ly49D. Journal of Experimental Medicine 197(7) pp. 919-925. [DOI] [Web of Science] [Pubmed]
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Zoete V., Michielin O., Karplus M., 2003. Protein-ligand binding free energy estimation using molecular mechanics and continuum electrostatics. Application to HIV-1 protease inhibitors. Journal of computer-aided molecular design 17(12) pp. 861-880. [DOI] [Web of Science] [Pubmed]
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Aseffa A., Gumy A., Launois P., MacDonald H.R., Louis J.A., Tacchini-Cottier F., 2002. The early IL-4 response to Leishmania major and the resulting Th2 cell maturation steering progressive disease in BALB/c mice are subject to the control of regulatory CD4+CD25+ T cells. Journal of Immunology 169(6) pp. 3232-3241. [Web of Science] [Pubmed]
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Batard P., Szollosi J., Luescher I., Cerottini J.C., MacDonald R., Romero P., 2002. Use of phycoerythrin and allophycocyanin for fluorescence resonance energy transfer analyzed by flow cytometry: advantages and limitations. Cytometry 48(2) pp. 97-105. [DOI] [Web of Science] [Pubmed]
Boon T, Cerottini J-C, 2002. Tumour antigens. pp. 115-126 in Oxford Textbook of Oncology, 2nd Edition. Oxford University Press, New York.
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Bullani R. R., Wehrli P., Viard-Leveugle I., Rimoldi D., Cerottini J. C., Saurat J. H., Tschopp J., French L. E., 06-2002. Frequent downregulation of Fas (CD95) expression and function in melanoma. Melanoma Research 12(3) pp. 263-70. [DOI] [Web of Science] [Pubmed]
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Cunningham A.F., Fallon P.G., Khan M., Vacheron S., Acha-Orbea H., MacLennan I.C., McKenzie A.N., Toellner K.M., 2002. Th2 activities induced during virgin T cell priming in the absence of IL-4, IL-13, and B cells. Journal of Immunology 169(6) pp. 2900-2906. [Web of Science] [Pubmed]
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Dutoit V., Rubio-Godoy V., Doucey M.A., Batard P., Liénard D., Rimoldi D., Speiser D., Guillaume P., Cerottini J.C., Romero P., Valmori D., 2002. Functional avidity of tumor antigen-specific CTL recognition directly correlates with the stability of MHC/peptide multimer binding to TCR. Journal of Immunology 168(3) pp. 1167-1171. [Web of Science] [Pubmed]
Dutoit V., Rubio-Godoy V., Pittet M.J., Zippelius A., Dietrich P.Y., Legal F.A., Guillaume P., Romero P., Cerottini J.C., Houghten R.A., Pinilla C., Valmori D., 2002. Degeneracy of antigen recognition as the molecular basis for the high frequency of naive A2/Melan-a peptide multimer(+) CD8(+) T cells in humans. Journal of Experimental Medicine 196(2) pp. 207-216. [DOI] [Web of Science] [Pubmed]
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Esslinger C., Romero P., MacDonald H.R., 2002. Efficient transduction of dendritic cells and induction of a T-cell response by third-generation lentivectors. Human gene therapy 13(9) pp. 1091-1100. [DOI] [Web of Science] [Pubmed]
Ferrero I., Held W., Wilson A., Tacchini-Cottier F., Radtke F., MacDonald H.R., 2002. Mouse CD11c(+) B220(+) Gr1(+) plasmacytoid dendritic cells develop independently of the T-cell lineage. Blood 100(8) pp. 2852-2857. [DOI] [Web of Science] [Pubmed]
Finke D, Acha-Orbea H, Mattis A, Lipp M, Kraehenbuhl J-P, 2002. CD4+ CD3- cells induce Peyer's patch development: Role of a4b1 integrin activation by CXCR5. Immunity 17 pp. 363-373.
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Miconnet I., Koenig S., Speiser D., Krieg A., Guillaume P., Cerottini J.C., Romero P., 2002. CpG are efficient adjuvants for specific CTL induction against tumor antigen-derived peptide. Journal of Immunology 168(3) pp. 1212-1218. [Web of Science] [Pubmed]
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Perrin G., Speiser D., Porret A., Quiquerez A. L., Walker P. R., Dietrich P. Y., 04-2002. Sister cytotoxic CD8+ T cell clones differing in natural killer inhibitory receptor expression in human astrocytoma. Immunology Letters 81(2) pp. 125-32. [DOI] [Web of Science] [Pubmed]
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Valmori D., Scheibenbogen C., Dutoit V., Nagorsen D., Asemissen A.M., Rubio-Godoy V., Rimoldi D., Guillaume P., Romero P., Schadendorf D., Lipp M., Dietrich P.Y., Thiel E., Cerottini J.C., Liénard D., Keilholz U., 2002. Circulating Tumor-reactive CD8(+) T cells in melanoma patients contain a CD45RA(+)CCR7(-) effector subset exerting ex vivo tumor-specific cytolytic activity. Cancer Research 62(6) pp. 1743-1750. [Web of Science] [Pubmed]
Wirth S., Bille F., Koenig S., Wehrli N., Miconnet I., Lévy F., Diggelmann H., Romero P., Acha-Orbea H., 2002. Testing mouse mammary tumor virus superantigen as adjuvant in cytotoxic T-lymphocyte responses against a melanoma tumor antigen. International Journal of Cancer 99(2) pp. 201-206. [DOI] [Pubmed]
Wirth S., Vessaz A., Krummenacher C., Baribaud F., Acha-Orbea H., Diggelmann H., 2002. Regions of mouse mammary tumor virus superantigen involved in interaction with the major histocompatibility complex class II I-A molecule. Journal of Virology 76(21) pp. 11172-11175. [DOI] [Web of Science] [Pubmed]
Wolfer A, 2002. The role of Notch1 during murine thymic T cell development. Université de Lausanne, Faculté de biologie et médecine, (dir.).
Wolfer A., Wilson A., Nemir M., MacDonald H.R., Radtke F., 2002. Inactivation of Notch1 impairs VDJbeta rearrangement and allows pre-TCR-independent survival of early alpha beta Lineage Thymocytes. Immunity 16(6) pp. 869-879. [Pubmed]
Zippelius A., Pittet M.J., Batard P., Rufer N., de Smedt M., Guillaume P., Ellefsen K., Valmori D., Liénard D., Plum J., MacDonald H.R., Speiser D.E., Cerottini J.C., Romero P., 2002. Thymic selection generates a large T cell pool recognizing a self-peptide in humans. The Journal of experimental medicine 195(4) pp. 485-494. [DOI] [Web of Science] [Pubmed]
Zippelius A., Pittet M.J., Romero P., 2002. Dissecting tumor antigen-specific CD8 T cell responses in cancer patients. pp. 8-12 in American Society for Histocompatibility and Immunogenetics. ASHI Quaterly.
2001
Arcaro A., Grégoire C., Bakker T.R., Baldi L., Jordan M., Goffin L., Boucheron N., Wurm F., van der Merwe P.A., Malissen B., Luescher I.F., 2001. CD8beta endows CD8 with efficient coreceptor function by coupling T cell receptor/CD3 to raft-associated CD8/p56(lck) complexes. The Journal of experimental medicine 194(10) pp. 1485-1495. [DOI] [Web of Science] [Pubmed]
Attinger A., MacDonald H.R., Acha-Orbea H., 2001. Lymphoid environment limits superantigen and antigen-induced T cell proliferation at high precursor frequency. European Journal of Immunology 31(3) pp. 884-893. [DOI] [Web of Science] [Pubmed]
Ayyoub M., Migliaccio M., Guillaume P., Liénard D., Cerottini J.C., Romero P., Lévy F., Speiser D.E., Valmori D., 2001. Lack of tumor recognition by hTERT peptide 540-548-specific CD8(+) T cells from melanoma patients reveals inefficient antigen processing. European journal of immunology 31(9) pp. 2642-51. [DOI] [Web of Science] [Pubmed]
Bachmann M.F., Gallimore A., Jones E., Ecabert B., Acha-Orbea H., Kopf M., 2001. Normal pathogen-specific immune responses mounted by CTLA-4-deficient T cells: a paradigm reconsidered. European Journal of Immunology 31(2) pp. 450-458. [DOI] [Web of Science] [Pubmed]
Baribaud F., Wirth S., Maillard I., Valsesia S., Acha-Orbea H., Diggelmann H., 2001. Identification of key amino acids of the mouse mammary tumor virus superantigen involved in the specific interaction with T-cell receptor V(beta) domains. Journal of Virology 75(16) pp. 7453-7461. [DOI] [Web of Science] [Pubmed]
Berset M., Cerottini J. P., Guggisberg D., Romero P., Burri F., Rimoldi D., Panizzon R. G., 01-2001. Expression of Melan-A/MART-1 antigen as a prognostic factor in primary cutaneous melanoma. International Journal of Cancer 95(1) pp. 73-7. [Web of Science] [Pubmed]
Blanchet J. S., Valmori D., Dufau I., Ayyoub M., Nguyen C., Guillaume P., Monsarrat B., Cerottini J. C., Romero P., Gairin J. E., 11-2001. A new generation of Melan-A/MART-1 peptides that fulfill both increased immunogenicity and high resistance to biodegradation: implication for molecular anti-melanoma immunotherapy. Journal of Immunology 167(10) pp. 5852-61. [Web of Science] [Pubmed]
Burri L, 2001. Proteasome assembly and identification of peptidases involved in antigen processing. Université de Lausanne, Faculté de biologie et médecine, (dir.).
Capone M., Troesch M., Eberl G., Hausmann B., Palmer E., MacDonald H.R., 2001. A critical role for the T cell receptor alpha-chain connecting peptide domain in positive selection of CD1-independent NKT cells. European Journal of Immunology 31(6) pp. 1867-1875. [DOI] [Web of Science] [Pubmed]
Coste I, Gauchat JF, Wilson A, Izui S, Jeannin P, Delneste Y, MacDonald HR, Bonnefoy JY, Renno T, 2001. Unavailability of CD147 leads to selective erythrocyte trapping in the spleen. Blood 97 pp. 3984-3988.
Coste I., Gauchat J.F., Wilson A., Izui S., Jeannin P., Delneste Y., MacDonald H.R., Bonnefoy J.Y., Renno T., 2001. Unavailability of CD147 leads to selective erythrocyte trapping in the spleen. Blood 97(12) pp. 3984-3988. [DOI] [Web of Science] [Pubmed]
Dietrich P.Y., Walker P.R., Quiquerez A.L., Perrin G., Dutoit V., Liénard D., Guillaume P., Cerottini J.C., Romero P., Valmori D., 2001. Melanoma patients respond to a cytotoxic T lymphocyte-defined self-peptide with diverse and nonoverlapping T-cell receptor repertoires. Cancer research 61(5) pp. 2047-54. [Web of Science] [Pubmed]
Doucey M.A., Legler D.F., Boucheron N., Cerottini J.C., Bron C., Luescher I.F., 2001. CTL activation is induced by cross-linking of TCR/MHC-peptide-CD8/p56lck adducts in rafts. European Journal of Immunology 31(5) pp. 1561-1570. [DOI] [Web of Science] [Pubmed]
Dutoit V., Rubio-Godoy V., Dietrich P.Y., Quiqueres A.L., Schnuriger V., Rimoldi D., Liénard D., Speiser D., Guillaume P., Batard P., Cerottini J.C., Romero P., Valmori D., 2001. Heterogeneous T-cell response to MAGE-A10(254-262): high avidity-specific cytolytic T lymphocytes show superior antitumor activity. Cancer research 61(15) pp. 5850-6. [Web of Science] [Pubmed]
Ferrero I., Wilson A., Beermann F., Held W., MacDonald H.R., 2001. T cell receptor specificity is critical for the development of epidermal gammadelta T cells. The Journal of Experimental Medicine 194(10) pp. 1473-1483. [DOI] [Web of Science] [Pubmed]
Finke D, Acha-Orbea H, 2001. Immune response to murine and feline retroviruses. pp. 6:125-157 in Retroviral Immunology. Humana Press, New York, USA.
Finke D., Acha-Orbea H., 2001. Differential migration of in vivo primed B and T lymphocytes to lymphoid and non-lymphoid organs. European Journal of Immunology 31(9) pp. 2603-2611. [DOI] [Web of Science] [Pubmed]
Finke D., Baribaud F., Diggelmann H., Acha-Orbea H., 2001. Extrafollicular plasmablast B cells play a key role in carrying retroviral infection to peripheral organs. Journal of Immunology 166(10) pp. 6266-6275. [Web of Science] [Pubmed]
Ioannidis V, 2001. Regulation of T and NK lymphocyte development by the transcription factor T cell factor-1 (TCF-1). Université de Lausanne, Faculté de biologie et médecine, (dir.).
Ioannidis V., Beermann F., Clevers H., Held W., 2001. The beta-catenin--TCF-1 pathway ensures CD4(+)CD8(+) thymocyte survival. Nature Immunology 2(8) pp. 691-697. [DOI] [Web of Science] [Pubmed]
Ioannidis V., Zimmer J., Beermann F., Held W., 2001. Cre recombinase-mediated inactivation of H-2Dd transgene expression: evidence for partial missing self-recognition by Ly49A NK cells. Journal of immunology 167(11) pp. 6256-6262. [Web of Science] [Pubmed]
Kalergis A.M., Boucheron N., Doucey M.A., Palmieri E., Goyarts E.C., Vegh Z., Luescher I.F., Nathenson S.G., 2001. Efficient T cell activation requires an optimal dwell-time of interaction between the TCR and the pMHC complex. Nature immunology 2(3) pp. 229-234. [DOI] [Web of Science] [Pubmed]
Klein M.A., Kaeser P.S., Schwarz P., Weyd H., Xenarios I., Zinkernagel R.M., Carroll M.C., Verbeek J.S., Botto M., Walport M.J., Molina H., Kalinke U., Acha-Orbea H., Aguzzi A., 2001. Complement facilitates early prion pathogenesis. Nature Medicine 7(4) pp. 488-492. [DOI] [Web of Science] [Pubmed]
Kuimov A.N., Kuprash D.V., Petrov V.N., Vdovichenko K.K., Scanlan M.J., Jongeneel C.V., Lagarkova M.A., Nedospasov S.A., 2001. Cloning and characterization of TNKL, a member of tankyrase gene family. Genes and Immunity 2(1) pp. 52-55. [DOI] [Web of Science] [Pubmed]
Legler D.F., Doucey M.A., Cerottini J.C., Bron C., Luescher I.F., 2001. Selective inhibition of CTL activation by a dipalmitoyl-phospholipid that prevents the recruitment of signaling molecules to lipid rafts. FASEB Journal 15(9) pp. 1601-1603. [DOI] [Web of Science] [Pubmed]
MacDonald H.R., Held W., 2001. CD8+ T cell development: CD4 to the rescue. Nature immunology 2(12) pp. 1091-1092. [DOI] [Web of Science] [Pubmed]
MacDonald H.R., Radtke F., Wilson A., 2001. T cell fate specification and alphabeta/gammadelta lineage commitment. Current opinion in immunology 13(2) pp. 219-224. [DOI] [Web of Science] [Pubmed]
MacDonald H.R., Wilson A., Radtke F., 2001. Notch1 and T-cell development: insights from conditional knockout mice. Trends in immunology 22(3) pp. 155-160. [Web of Science] [Pubmed]
Maillard I., Launois P., Himmelrich H., Acha-Orbea H., Diggelmann H., Locksley R.M., Louis J.A., 2001. Functional plasticity of the LACK-reactive Vbeta4-Valpha8 CD4(+) T cells normally producing the early IL-4 instructing Th2 cell development and susceptibility to Leishmania major in BALB / c mice. European Journal of Immunology 31(4) pp. 1288-1296. [Web of Science] [Pubmed]
Michielin O, 2001. Molecular modeling of the TCR-peptide-MHC complex: application to melanoma immunotherapy. Université de Lausanne, Faculté de biologie et médecine, (dir.).
Miconnet I., Coste I., Beermann F., Haeuw J. F., Cerottini J. C., Bonnefoy J. Y., Romero P., Renno T., 04-2001. Cancer vaccine design: a novel bacterial adjuvant for peptide-specific CTL induction. Journal of Immunology 166(7) pp. 4612-9. [Web of Science] [Pubmed]
Pagni M., Jongeneel C. V., 03-2001. Making sense of score statistics for sequence alignments. Briefings in Bioinformatics 2(1) pp. 51-67. [Pubmed]
Pinilla C., Rubio-Godoy V., Dutoit V., Guillaume P., Simon R., Zhao Y., Houghten R. A., Cerottini J. C., Romero P., Valmori D., 07-2001. Combinatorial peptide libraries as an alternative approach to the identification of ligands for tumor-reactive cytolytic T lymphocytes. Cancer Research 61(13) pp. 5153-60. [Web of Science] [Pubmed]
Pittet M, 2001. Dissecting tumor-specific CD8 T cell responses in humans. Université de Lausanne, Faculté de biologie et médecine, (dir.).
Pittet M.J., Speiser D.E., Liénard D., Valmori D., Guillaume P., Dutoit V., Rimoldi D., Lejeune F., Cerottini J.C., Romero P., 03-2001. Expansion and functional maturation of human tumor antigen-specific CD8+ T cells after vaccination with antigenic peptide. Clinical Cancer Research 7(3 Suppl.) pp. 796s-803s. [Web of Science] [Pubmed]
Pittet M.J., Speiser D.E., Valmori D., Rimoldi D., Liénard D., Lejeune F., Cerottini J.C., Romero P., 07-2001. Ex vivo analysis of tumor antigen specific CD8+ T cell responses using MHC/peptide tetramers in cancer patients. International immunopharmacology 1(7) pp. 1235-1247. [DOI] [Web of Science] [Pubmed]
Pittet M.J., Zippelius A., Speiser D.E., Assenmacher M., Guillaume P., Valmori D., Liénard D., Lejeune F., Cerottini J.C., Romero P., 06-2001. Ex vivo IFN-gamma secretion by circulating CD8 T lymphocytes: implications of a novel approach for T cell monitoring in infectious and malignant diseases. Journal of Immunology 166(12) pp. 7634-7640. [Web of Science] [Pubmed]
Rangarajan A., Talora C., Okuyama R., Nicolas M., Mammucari C., Oh H., Aster J.C., Krishna S., Metzger D., Chambon P., Miele L., Aguet M., Radtke F., Dotto G.P., 2001. Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation. EMBO Journal 20(13) pp. 3427-3436. [DOI] [Web of Science] [Pubmed]
Rimoldi D., Muehlethaler K., Salvi S., Valmori D., Romero P., Cerottini J.C., Levy F., 11-2001. Subcellular localization of the melanoma-associated protein Melan-AMART-1 influences the processing of its HLA-A2-restricted epitope. Journal of Biological Chemistry 276(46) pp. 43189-43196. [DOI] [Web of Science] [Pubmed]
Robert B., Guillaume P., Luescher I., Doucey M.A., Cerottini J.C., Romero P., Mach J.P., 2001. Redirecting anti-viral CTL against cancer cells by surface targeting of monomeric MHC class I-viral peptide conjugated to antibody fragments. Cancer Immunity 1(2) pp. 1-13. [url editor site] [Pubmed]
Romero P., Dutoit V., Rubio-Godoy V., Liénard D., Speiser D., Guillaume P., Servis K., Rimoldi D., Cerottini J.C., Valmori D., 2001. CD8+ T-cell response to NY-ESO-1: relative antigenicity and in vitro immunogenicity of natural and analogue sequences. Clinical Cancer Research 7(3 Suppl.) pp. 766-772. [Web of Science] [Pubmed]
Rubio-Godoy V., Dutoit V., Rimoldi D., Lienard D., Lejeune F., Speiser D., Guillaume P., Cerottini J.C., Romero P., Valmori D., 08-2001. Discrepancy between ELISPOT IFN-gamma secretion and binding of A2/peptide multimers to TCR reveals interclonal dissociation of CTL effector function from TCR-peptide/MHC complexes half-life. Proceedings of the National Academy of Sciences of the United States of America 98(18) pp. 10302-10307. [DOI] [Web of Science] [Pubmed]
Rufer N, Migliaccio M, Antonchuk J, Humphries RK, Roosnek E, Lansdorp PM, 2001. Transfer of the human telomerase reverse transcriptase (TERT) gene into T lymphocytes results in extension of replicative potential. Blood 98 pp. 597-603. [Web of Science]
Schneider P., Takatsuka H., Wilson A., Mackay F., Tardivel A., Lens S., Cachero T.G., Finke D., Beermann F., Tschopp J., 2001. Maturation of marginal zone and follicular B cells requires B cell activating factor of the tumor necrosis factor family and is independent of B cell maturation antigen. Journal of Experimental Medicine 194(11) pp. 1691-1697. [DOI] [Web of Science] [Pubmed]
Schneider P., Takatsuka H., Wilson A., Mackay F., Tardivel A., Lens S., Cachero T.G., Finke D., Beermann F., Tschopp J., 2001. Maturation of marginal zone and follicular B cells requires B cell activating factor of the tumor necrosis factor family and is independent of B cell maturation antigen. Journal of Experimental Medicine 194(11) pp. 1691-1697. [Document] [DOI] [Web of Science] [Pubmed]
Sliz P., Michielin O., Cerottini J.C., Luescher I., Romero P., Karplus M., Wiley D.C., 2001. Crystal structures of two closely related but antigenically distinct HLA-A2/melanocyte-melanoma tumor-antigen peptide complexes. Journal of immunology 167(6) pp. 3276-3284. [Web of Science] [Pubmed]
Speiser D. E., Colonna M., Ayyoub M., Cella M., Pittet M. J., Batard P., Valmori D., Guillaume P., Lienard D., Cerottini J. C., Romero P., 12-2001. The activatory receptor 2B4 is expressed in vivo by human CD8+ effector alpha beta T cells. Journal of Immunology 167(11) pp. 6165-70. [Web of Science] [Pubmed]
Speiser D.E., Migliaccio M., Pittet M.J., Valmori D., Liénard D., Lejeune F., Reichenbach P., Guillaume P., Lüscher I., Cerottini J.C., Romero P., 2001. Human CD8(+) T cells expressing HLA-DR and CD28 show telomerase activity and are distinct from cytolytic effector T cells. European journal of immunology 31(2) pp. 459-66. [DOI] [Web of Science] [Pubmed]
Trobonjaca Z., Leithäuser F., Möller P., Bluethmann H., Koezuka Y., MacDonald H.R., Reimann J., 2001. MHC-II-independent CD4+ T cells induce colitis in immunodeficient RAG-/- hosts. Journal of Immunology 166(6) pp. 3804-3812. [Web of Science] [Pubmed]
Valmori D., Dutoit V., Rubio-Godoy V., Chambaz C., Liénard D., Guillaume P., Romero P., Cerottini J.C., Rimoldi D., 2001. Frequent cytolytic T-cell responses to peptide MAGE-A10(254-262) in melanoma. Cancer research 61(2) pp. 509-12. [Web of Science] [Pubmed]
Voehringer D., Blaser C., Brawand P., Raulet D.H., Hanke T., Pircher H., 2001. Viral infections induce abundant numbers of senescent CD8 T cells. Journal of Immunology 167(9) pp. 4838-4843. [Pubmed]
Waldburger J.M., Suter T., Fontana A., Acha-Orbea H., Reith W., 2001. Selective abrogation of major histocompatibility complex class II expression on extrahematopoietic cells in mice lacking promoter IV of the class II transactivator gene. Journal of Experimental Medicine 194(4) pp. 393-406. [DOI] [Web of Science] [Pubmed]
Wehrli N., Legler D.F., Finke D., Toellner K.M., Loetscher P., Baggiolini M., MacLennan I.C., Acha-Orbea H., 2001. Changing responsiveness to chemokines allows medullary plasmablasts to leave lymph nodes. European Journal of Immunology 31(2) pp. 609-616. [DOI] [Web of Science] [Pubmed]
Wilson A., MacDonald H.R., Radtke F., 2001. Notch 1-deficient common lymphoid precursors adopt a B cell fate in the thymus. The Journal of experimental medicine 194(7) pp. 1003-1012. [DOI] [Web of Science] [Pubmed]
Wilson A., Maréchal C., MacDonald H.R., 2001. Biased V beta usage in immature thymocytes is independent of DJ beta proximity and pT alpha pairing. Journal of Immunology 166(1) pp. 51-57. [Web of Science] [Pubmed]
Wolfer A., Bakker T., Wilson A., Nicolas M., Ioannidis V., Littman D.R., Lee P.P., Wilson C.B., Held W., MacDonald H.R., Radtke F., 2001. Inactivation of Notch 1 in immature thymocytes does not perturb CD4 or CD8T cell development. Nature immunology 2(3) pp. 235-241. [DOI] [Web of Science] [Pubmed]
2000
Arcaro A., Grégoire C., Boucheron N., Stotz S., Palmer E., Malissen B., Luescher I.F., 2000. Essential role of CD8 palmitoylation in CD8 coreceptor function. Journal of immunology 165(4) pp. 2068-2076. [Web of Science] [Pubmed]
Attinger A., Acha-Orbea H., MacDonald H.R., 2000. Cutting edge: cell autonomous rather than environmental factors control bacterial superantigen-induced T cell anergy in vivo. Journal of Immunology 165(3) pp. 1171-1174. [Web of Science] [Pubmed]
Aude-Garcia C, Attinger A, Housset D, MacDonald HR, Acha-Orbea H, Marche PN, Jouvin-Marche E, 2000. Pairing of Vß6 with certain Va2 family members prevents T cells deletion by Mtv-7 superantigen. Molecular Immunology 37 pp. 1005-1012.
Aude-Garcia C., Attinger A., Housset D., MacDonald H.R., Acha-Orbea H., Marche P.N., Jouvin-Marche E., 2000. Pairing of Vbeta6 with certain Valpha2 family members prevents T cell deletion by Mtv-7 superantigen. Molecular Immunology 37(16) pp. 1005-1012. [Web of Science] [Pubmed]
Berard F., Blanco P., Davoust J., Neidhart-Berard E. M., Nouri-Shirazi M., Taquet N., Rimoldi D., Cerottini J. C., Banchereau J., Palucka A. K., 12-2000. Cross-priming of naive CD8 T cells against melanoma antigens using dendritic cells loaded with killed allogeneic melanoma cells. Journal of Experimental Medicine 192(11) pp. 1535-44. [DOI] [Web of Science] [Pubmed]
Bonelo A., Valmori D., Triponez F., Tiercy J. M., Mentha G., Oberholzer J., Champagne P., Romero J. F., Esposito F., Nebie I., Barbey C., Romero P., Herrera S., Corradin G., Lopez J. A., 11-2000. Generation and characterization of malaria-specific human CD8(+) lymphocyte clones: effect of natural polymorphism on T cell recognition and endogenous cognate antigen presentationby liver cells. European Journal of Immunology 30(11) pp. 3079-88. [DOI] [Web of Science] [Pubmed]
Brawand P., Lemonnier F.A., MacDonald H.R., Cerottini J.C., Held W., 2000. Transgenic expression of Ly49A on T cells impairs a specific antitumor response. Journal of immunology 165(4) pp. 1871-1876. [Web of Science] [Pubmed]
Burri L., Hockendorff J., Boehm U., Klamp T., Dohmen R. J., Levy F., 09-2000. Identification and characterization of a mammalian protein interacting with 20S proteasome precursors. Proceedings of the National Academy of Sciences of the United States of America 97(19) pp. 10348-53. [DOI] [Web of Science] [Pubmed]
Cerottini J.C., Lejeune F., Leyvraz S., Romero P., 2000. L'immunothérapie adoptive. Médecine et Hygiène 58(2299) pp. 992-993.
Chapuis A.G., Paolo Rizzardi G., D'Agostino C., Attinger A., Knabenhans C., Fleury S., Acha-Orbea H., Pantaleo G., 2000. Effects of mycophenolic acid on human immunodeficiency virus infection in vitro and in vivo. Nature Medicine 6(7) pp. 762-768. [DOI] [Web of Science] [Pubmed]
Colucci F., Guy-Grand D., Wilson A., Turner M., Schweighoffer E., Tybulewicz V.L., Di Santo J.P., 2000. A new look at Syk in alpha beta and gamma delta T cell development using chimeric mice with a low competitive hematopoietic environment. Journal of Immunology 164(10) pp. 5140-5145. [Pubmed]
Di Santo J. P., Radtke F., Rodewald H. R., 04-2000. To be or not to be a pro-T? Current Opinion in Immunology 12(2) pp. 159-65. [Pubmed]
Dias Neto E., Correa R.G., Verjovski-Almeida S., Briones M.R., Nagai M.A., da Silva W., Zago M.A., Bordin S., Costa F.F., Goldman G.H., Carvalho A.F., Matsukuma A., Baia G.S., Simpson D.H., Brunstein A., de Oliveira P.S., Bucher P., Jongeneel C.V., O'Hare M.J., Soares F., Brentani R.R., Reis L.F., de Souza S.J., Simpson A.J., 2000. Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. Proceedings of the National Academy of Sciences of the United States of America 97(7) pp. 3491-3496. [Pubmed]
Eberl G., Brawand P., MacDonald H.R., 2000. Selective bystander proliferation of memory CD4+ and CD8+ T cells upon NK T or T cell activation. Journal of Immunology 165(8) pp. 4305-4311. [Web of Science] [Pubmed]
Eberl G., MacDonald H.R., 2000. Selective induction of NK cell proliferation and cytotoxicity by activated NKT cells. European Journal of Immunology 30(4) pp. 985-992. [DOI] [Web of Science] [Pubmed]
Gasser S., Corthésy P., Beerman F., MacDonald H.R., Nabholz M., 2000. Constitutive expression of a chimeric receptor that delivers IL-2/IL-15 signals allows antigen-independent proliferation of CD8+CD44high but not other T cells. Journal of Immunology 164(11) pp. 5659-5667. [Web of Science] [Pubmed]
Gonzalez J. M., Peter K., Esposito F., Nebie I., Tiercy J. M., Bonelo A., Arevalo-Herrera M., Valmori D., Romero P., Herrera S., Corradin G., Lopez J. A., 10-2000. HLA-A*0201 restricted CD8+ T-lymphocyte responses to malaria: identification of new Plasmodium falciparum epitopes by IFN-gamma ELISPOT. Parasite Immunology 22(10) pp. 501-14. [DOI] [Web of Science] [Pubmed]
Held W., Lowin-Kropf B., Raulet D.H., 2000. Generation of short-term murine natural killer cell clones to analyze Ly49 gene expression. Methods in molecular biology 121 pp. 5-12. [DOI] [Pubmed]
Holler N., Kataoka T., Bodmer J.L., Romero P., Romero J., Deperthes D., Engel J., Tschopp J., Schneider P., 2000. Development of improved soluble inhibitors of FasL and CD40L based on oligomerized receptors. Journal of Immunological Methods 237(1-2) pp. 159-173. [Document] [DOI] [Web of Science] [Pubmed]
Hudrisier D., Luescher I. F., 2000. Antigen recognition by CD8 + CTLs. pp. 25-43 in Sitkovsky M.V., Henkart P.A. (eds.) Cytotoxic cells : basic mechanisms and medical applications. Lippincott Williams & Wilkins, Philadelphia.
Jeannin P., Renno T., Goetsch L., Miconnet I., Aubry J. P., Delneste Y., Herbault N., Baussant T., Magistrelli G., Soulas C., Romero P., Cerottini J. C., Bonnefoy J. Y., 12-2000. OmpA targets dendritic cells, induces their maturation and delivers antigen into the MHC class I presentation pathway. Nature Immunology 1(6) pp. 502-9. [DOI] [Web of Science] [Pubmed]
Jongeneel C.V., 02-2000. Searching the expressed sequence tag (EST) databases: panning for genes. Briefings in Bioinformatics 1(1) pp. 76-92. [Pubmed]
Jongeneel C.V., 2000. The need for a human gene index. Bioinformatics 16(12) pp. 1059-1061. [Web of Science] [Pubmed]
Leimeister C., Dale K., Fischer A., Klamt B., Hrabe de Angelis M., Radtke F., McGrew M. J., Pourquie O., Gessler M., 11-2000. Oscillating expression of c-Hey2 in the presomitic mesoderm suggests that the segmentation clock may use combinatorial signaling through multiple interacting bHLH factors. Developmental Biology 227(1) pp. 91-103. [DOI] [Pubmed]
Lowin-Kropf B., Held W., 2000. Positive impact of inhibitory Ly49 receptor-MHC class I interaction on NK cell development. Journal of immunology 165(1) pp. 91-95. [Web of Science] [Pubmed]
Lowin-Kropf B., Kunz B., Beermann F., Held W., 2000. Impaired natural killing of MHC class I-deficient targets by NK cells expressing a catalytically inactive form of SHP-1. Journal of immunology 165(3) pp. 1314-1321. [Web of Science] [Pubmed]
MacDonald H.R., 2000. CD1d-glycolipid tetramers: A new tool to monitor natural killer T cells in health and disease. The Journal of experimental medicine 192(5) pp. F15-F20. [DOI] [Web of Science] [Pubmed]
Michielin O., Luescher I., Karplus M., 2000. Modeling of the TCR-MHC-peptide complex. Journal of molecular biology 300(5) pp. 1205-1235. [DOI] [Web of Science] [Pubmed]
Miconnet I., Servis C., Cerottini J.C., Romero P., Lévy F., 2000. Amino acid identity and/or position determines the proteasomal cleavage of the HLA-A*0201-restricted peptide tumor antigen MAGE-3271-279. Journal of Biological Chemistry 275(35) pp. 26892-26897. [DOI] [Web of Science] [Pubmed]
Migliaccio M., Amacker M., Just T., Reichenbach P., Valmori D., Cerottini J.C., Romero P., Nabholz M., 2000. Ectopic human telomerase catalytic subunit expression maintains telomere length but is not sufficient for CD8+ T lymphocyte immortalization. Journal of Immunology 165(9) pp. 4978-4984. [Web of Science] [Pubmed]
Morel S., Levy F., Burlet-Schiltz O., Brasseur F., Probst-Kepper M., Peitrequin A. L., Monsarrat B., Van Velthoven R., Cerottini J. C., Boon T., Gairin J. E., Van den Eynde B. J., 01-2000. Processing of some antigens by the standard proteasome but not by the immunoproteasome results in poor presentation by dendritic cells. Immunity 12(1) pp. 107-17. [DOI] [Web of Science] [Pubmed]
Nguyen L. T., McKall-Faienza K., Zakarian A., Speiser D. E., Mak T. W., Ohashi P. S., 02-2000. TNF receptor 1 (TNFR1) and CD95 are not required for T cell deletion after virus infection but contribute to peptide-induced deletion under limited conditions. European Journal of Immunology 30(2) pp. 683-8. [DOI] [Web of Science] [Pubmed]
Noppen C., Levy F., Burri L., Zajac P., Remmel E., Schaefer C., Luscher U., Heberer M., Spagnoli G. C., 07-2000. Naturally processed and concealed HLA-A2.1-restricted epitopes from tumor-associated antigen tyrosinase-related protein-2. International Journal of Cancer 87(2) pp. 241-6. [Web of Science] [Pubmed]
Pittet M. J., Speiser D. E., Valmori D., Cerottini J. C., Romero P., 02-2000. Cutting edge: cytolytic effector function in human circulating CD8+ T cells closely correlates with CD56 surface expression. Journal of Immunology 164(3) pp. 1148-52. [Web of Science] [Pubmed]
Radtke F., Ferrero I., Wilson A., Lees R., Aguet M., MacDonald H.R., 2000. Notch1 deficiency dissociates the intrathymic development of dendritic cells and T cells. Journal of Experimental Medicine 191(7) pp. 1085-1094. [DOI] [Web of Science] [Pubmed]
Rimoldi D., Rubio-Godoy V., Dutoit V., Lienard D., Salvi S., Guillaume P., Speiser D., Stockert E., Spagnoli G., Servis C., Cerottini J.C., Lejeune F., Romero P., Valmori D., 2000. Efficient simultaneous presentation of NY-ESO-1/LAGE-1 primary and nonprimary open reading frame-derived CTL epitopes in melanoma. Journal of Immunology 165(12) pp. 7253-7261. [Web of Science] [Pubmed]
Rimoldi D., Salvi S., Schultz-Thater E., Spagnoli G. C., Cerottini J. C., 06-2000. Anti-MAGE-3 antibody 57B and anti-MAGE-1 antibody 6C1 can be used to study different proteins of the MAGE-A family. International Journal of Cancer 86(5) pp. 749-51. [Web of Science] [Pubmed]
Robert B., Guillaume P., Luescher I., Romero P., Mach J.P., 2000. Antibody-conjugated MHC class I tetramers can target tumor cells for specific lysis by T lymphocytes. European journal of immunology 30(11) pp. 3165-7310. [DOI] [Web of Science] [Pubmed]
Romero P., Pittet M.J., Valmori D., Speiser D.E., Cerundolo V., Liénard D., Lejeune F., Cerottini J.C., 2000. Immune monitoring in cancer immunotherapy. Ernst Schering Research Foundation workshop 30 pp. 75-97. [Pubmed]
Scheibenbogen C., Romero P., Rivoltini L., Herr W., Schmittel A., Cerottini J. C., Woelfel T., Eggermont A. M., Keilholz U., 10-2000. Quantitation of antigen-reactive T cells in peripheral blood by IFNgamma-ELISPOT assay and chromium-release assay: a four-centre comparative trial. Journal of Immunological Methods 244(1-2) pp. 81-9. [DOI] [Web of Science] [Pubmed]
Valmori D., Dutoit V., Liénard D., Lejeune F., Speiser D., Rimoldi D., Cerundolo V., Dietrich P.Y., Cerottini J.C., Romero P., 07-2000. Tetramer-guided analysis of TCR beta-chain usage reveals a large repertoire of melan-A-specific CD8+ T cells in melanoma patients. Journal of Immunology 165(1) pp. 533-538. [Web of Science] [Pubmed]
Valmori D., Dutoit V., Liénard D., Rimoldi D., Pittet M.J., Champagne P., Ellefsen K., Sahin U., Speiser D., Lejeune F., Cerottini J.C., Romero P., 08-2000. Naturally occurring human lymphocyte antigen-A2 restricted CD8+ T-cell response to the cancer testis antigen NY-ESO-1 in melanoma patients. Cancer research 60(16) pp. 4499-4506. [Web of Science] [Pubmed]
Valmori D., Lévy F., Miconnet I., Zajac P., Spagnoli G.C., Rimoldi D., Liénard D., Cerundolo V., Cerottini J.C., Romero P., 2000. Induction of potent antitumor CTL responses by recombinant vaccinia encoding a melan-A peptide analogue. Journal of Immunology 164(2) pp. 1125-1131. [Web of Science] [Pubmed]
Wilson A., Ferrero I., MacDonald H.R., Radtke F., 2000. Cutting edge: an essential role for Notch-1 in the development of both thymus-independent and -dependent T cells in the gut. Journal of immunology 165(10) pp. 5397-5400. [Web of Science] [Pubmed]
Wittelsberger A, Keller M, Scarpellino L, Patiny L, Acha-Orbea H, Mutter M, 2000. Pseudoprolines: Targeting a cis conformation in a mimetic of the gp120 V3 loop of HIV-1. Angew. Chem. Int. Ed. 39 pp. 1111-1115.
1999
Acha-Orbea H., Finke D., Attinger A., Schmid S., Wehrli N., Vacheron S., Xenarios I., Scarpellino L., Toellner K.M., MacLennan I.C., Luther S.A., 1999. Interplays between mouse mammary tumor virus and the cellular and humoral immune response. Immunological Reviews 168 pp. 287-303. [DOI] [Web of Science] [Pubmed]
Ardavín C., Martín P., Ferrero I., Azcoitia I., Anjuère F., Diggelmann H., Luthi F., Luther S., Acha-Orbea H., 1999. B cell response after MMTV infection: extrafollicular plasmablasts represent the main infected population and can transmit viral infection. Journal of Immunology 162(5) pp. 2538-2545. [Web of Science] [Pubmed]
Astori M., Finke D., Karapetian O., Acha-Orbea H., 1999. Development of T-B cell collaboration in neonatal mice. International Immunology 11(3) pp. 445-451. [Web of Science] [Pubmed]
Bachmann M. F., Speiser D. E., Mak T. W., Ohashi P. S., 07-1999. Absence of co-stimulation and not the intensity of TCR signaling is critical for the induction of T cell unresponsiveness in vivo. European Journal of Immunology 29(7) pp. 2156-66. [DOI] [Web of Science] [Pubmed]
Bakker T.R., Reed D., Renno T., Jongeneel C.V., 01-1999. Efficient adenoviral transfer of NF-kappaB inhibitor sensitizes melanoma to tumor necrosis factor-mediated apoptosis. International Journal of Cancer 80(2) pp. 320-323. [Web of Science] [Pubmed]
Bakker T.R., Renno T., Jongeneel C.V., 03-1999. Impaired fetal thymocyte development after efficient adenovirus-mediated inhibition of NF-kappa B activation. Journal of Immunology 162(6) pp. 3456-3462. [Web of Science] [Pubmed]
Baribaud F., Maillard I., Vacheron S., Brocker T., Diggelmann H., Acha-Orbea H., 1999. Role of dendritic cells in the immune response induced by mouse mammary tumor virus superantigen. Journal of Virology 73(10) pp. 8403-8410. [Web of Science] [Pubmed]
Baribaud F., Shaw A.V., Scarpellino L., Diggelmann H., Acha-Orbea H., 1999. Preferential binding of mouse mammary tumor virus to B lymphocytes. Journal of Virology 73(9) pp. 7899-7902. [Web of Science] [Pubmed]
Bour H., Michielin O., Bousso P., Cerottini J.C., MacDonald H.R., 1999. Dramatic influence of V beta gene polymorphism on an antigen-specific CD8+ T cell response in vivo. Journal of immunology 162(8) pp. 4647-4656. [Web of Science] [Pubmed]
Brawand P, 1999. Longitudinal analysis of specific CD8+ T cell response to Moloney Leukemia virus-induced tumor cells. Université de Lausanne, Faculté de biologie et médecine, (dir.).
Ciernik I.F., Romero P., Berzofsky J.A., Carbone D.P., 1999. Ionizing radiation enhances immunogenicity of cells expressing a tumor-specific T-cell epitope. International journal of radiation oncology, biology, physics 45(3) pp. 735-41. [DOI] [Web of Science] [Pubmed]
Dunbar P. R., Chen J. L., Chao D., Rust N., Teisserenc H., Ogg G. S., Romero P., Weynants P., Cerundolo V., 06-1999. Cutting edge: rapid cloning of tumor-specific CTL suitable for adoptive immunotherapy of melanoma. Journal of Immunology 162(12) pp. 6959-62. [Web of Science] [Pubmed]
Eberl G., Fehling H.J., von Boehmer H., MacDonald H.R., 1999. Absolute requirement for the pre-T cell receptor alpha chain during NK1.1+ TCRalphabeta cell development. European Journal of Immunology 29(6) pp. 1966-1971. [Web of Science] [Pubmed]
Eberl G., Lees R., Smiley S.T., Taniguchi M., Grusby M.J., MacDonald H.R., 1999. Tissue-specific segregation of CD1d-dependent and CD1d-independent NK T cells. Journal of Immunology 162(11) pp. 6410-6419. [Web of Science] [Pubmed]
Eberl G., Lowin-Kropf B., MacDonald H.R., 1999. Cutting edge: NKT cell development is selectively impaired in Fyn- deficient mice. Journal of Immunology 163(8) pp. 4091-4094. [Web of Science] [Pubmed]
Fleischhauer K., Agostino A., Zino E., Mazzi B., Benazzi E., Arevalo-Herrera M., Herrera S., Bordignon C., Romero P., 1999. Molecular characterization of HLA class I in Colombians carrying HLA-A2: high allelic diversity and frequency of heterozygotes at the HLA-B locus. Tissue Antigens 53(6) pp. 519-526. [DOI] [Web of Science] [Pubmed]
Gerber H.P., Hillan K.J., Ryan A.M., Kowalski J., Keller G.A., Rangell L., Wright B.D., Radtke F., Aguet M., Ferrara N., 1999. VEGF is required for growth and survival in neonatal mice. Development 126(6) pp. 1149-1159. [Web of Science] [Pubmed]
Held W., Kunz B., Ioannidis V., Lowin-Kropf B., 1999. Mono-allelic Ly49 NK cell receptor expression. Seminars in immunology 11(5) pp. 349-355. [DOI] [Web of Science] [Pubmed]
Held W., Kunz B., Lowin-Kropf B., van de Wetering M., Clevers H., 1999. Clonal acquisition of the Ly49A NK cell receptor is dependent on the trans-acting factor TCF-1. Immunity 11(4) pp. 433-442. [DOI] [Web of Science] [Pubmed]
Iseli C., Jongeneel C.V., Bucher P., 1999. ESTScan: a program for detecting, evaluating, and reconstructing potential coding regions in EST sequences. Proceedings / ... International Conference On Intelligent Systems For Molecular Biology pp. 138-148. [Pubmed]
Kessler B., Michielin O., Blanchard C.L., Apostolou I., Delarbre C., Gachelin G., Grégoire C., Malissen B., Cerottini J.C., Wurm F., Karplus M., Luescher I.F., 1999. T cell recognition of hapten. Anatomy of T cell receptor binding of a H-2kd-associated photoreactive peptide derivative. The Journal of biological chemistry 274(6) pp. 3622-3631. [DOI] [Web of Science] [Pubmed]
Knecht H, Berger C, McQuain C, Rothenberger S, Bachmann E, Martin J, Esslinger C, Drexler HG, Cai YC, Quesenberry PJ, Odermatt BF, 1999. Latent membrane protein 1 associated signaling pathways are important in tumor cells of Epstein-Barr virus negative Hodgkin's disease. Oncogene 18 pp. 7161-7167.
Kwon Y. T., Levy F., Varshavsky A., 06-1999. Bivalent inhibitor of the N-end rule pathway. Journal of Biological Chemistry 274(25) pp. 18135-9. [DOI] [Web of Science] [Pubmed]
Lengacher S., Reed D., Heumann D., Jongeneel C.V., 06-1999. Genomic organization and chromosomal localization of the mouse lipopolysaccharide binding protein gene. Immunogenetics 49(6) pp. 553-556. [DOI] [Web of Science] [Pubmed]
Levy F., Johnston J. A., Varshavsky A., 01-1999. Analysis of a conditional degradation signal in yeast and mammalian cells. European Journal of Biochemistry 259(1-2) pp. 244-52. [DOI] [Web of Science] [Pubmed]
Marchand M., van Baren N., Weynants P., Brichard V., Dréno B., Tessier M.H., Rankin E., Parmiani G., Arienti F., Humblet Y., Bourlond A., Vanwijck R., Liénard D., Beauduin M., Dietrich P.Y., Russo V., Kerger J., Masucci G., Jäger E., De Greve J., Atzpodien J., Brasseur F., Coulie P.G., van der Bruggen P., Boon T., 1999. Tumor regressions observed in patients with metastatic melanoma treated with an antigenic peptide encoded by gene MAGE-3 and presented by HLA-A1. International Journal of Cancer 80(2) pp. 219-230. [Pubmed]
Marguerat S., MacDonald H.R., Kraehenbuhl J.P., van Meerwijk J.P., 1999. Protection from radiation-induced colitis requires MHC class II antigen expression by cells of hemopoietic origin. Journal of immunology 163(7) pp. 4033-4040. [Web of Science] [Pubmed]
Men Y., Miconnet I., Valmori D., Rimoldi D., Cerottini J. C., Romero P., 03-1999. Assessment of immunogenicity of human Melan-A peptide analogues in HLA-A*0201/Kb transgenic mice. Journal of Immunology 162(6) pp. 3566-73. [Web of Science] [Pubmed]
Nguyen L. T., Duncan G. S., Mirtsos C., Ng M., Speiser D. E., Shahinian A., Marino M. W., Mak T. W., Ohashi P. S., Yeh W. C., 09-1999. TRAF2 deficiency results in hyperactivity of certain TNFR1 signals and impairment of CD40-mediated responses. Immunity 11(3) pp. 379-89. [DOI] [Web of Science] [Pubmed]
Pittet M. J., Valmori D., Dunbar P. R., Speiser D. E., Lienard D., Lejeune F., Fleischhauer K., Cerundolo V., Cerottini J. C., Romero P., 09-1999. High frequencies of naive Melan-A/MART-1-specific CD8(+) T cells in a large proportion of human histocompatibility leukocyte antigen (HLA)-A2 individuals. Journal of Experimental Medicine 190(5) pp. 705-15. [DOI] [Web of Science] [Pubmed]
Radtke F., Wilson A., Stark G., Bauer M., van Meerwijk J., MacDonald H.R., Aguet M., 1999. Deficient T cell fate specification in mice with an induced inactivation of Notch1. Immunity 10(5) pp. 547-558. [DOI] [Web of Science] [Pubmed]
Renno T., Attinger A., Locatelli S., Bakker T., Vacheron S., MacDonald H.R., 1999. Cutting edge: apoptosis of superantigen-activated T cells occurs preferentially after a discrete number of cell divisions in vivo. Journal of Immunology 162(11) pp. 6312-6315. [Web of Science] [Pubmed]
Rimoldi D., Salvi S., Reed D., Coulie P., Jongeneel V. C., De Plaen E., Brasseur F., Rodriguez A. M., Boon T., Cerottini J. C., 09-1999. cDNA and protein characterization of human MAGE-10. International Journal of Cancer 82(6) pp. 901-7. [DOI] [Web of Science] [Pubmed]
Scanlan M.J., Gordan J.D., Williamson B., Stockert E., Bander N.H., Jongeneel V., Gure A.O., Jäger D., Jäger E., Knuth A., Chen Y.T., Old L.J., 1999. Antigens recognized by autologous antibody in patients with renal-cell carcinoma. International Journal of Cancer 83(4) pp. 456-464. [Pubmed]
Schneider P., MacKay F., Steiner V., Hofmann K., Bodmer J.L., Holler N., Ambrose C., Lawton P., Bixler S., Acha-Orbea H., Valmori D., Romero P., Werner-Favre C., Zubler R.H., Browning J.L., Tschopp J., 1999. BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth. Journal of Experimental Medicine 189(11) pp. 1747-1756. [Document] [DOI] [Web of Science] [Pubmed]
Serrano A., Lethé B., Delroisse J.M., Lurquin C., De Plaen E., Brasseur F., Rimoldi D., Boon T., 1999. Quantitative evaluation of the expression of MAGE genes in tumors by limiting dilution of cDNA libraries. International Journal of Cancer. 83(5) pp. 664-669. [Pubmed]
Speiser D.E., Pittet M.J., Valmori D., Dunbar R., Rimoldi D., Liénard D., MacDonald H.R., Cerottini J.C., Cerundolo V., Romero P., 1999. In vivo expression of natural killer cell inhibitory receptors by human melanoma-specific cytolytic T lymphocytes. The Journal of experimental medicine 190(6) pp. 775-782. [DOI] [Web of Science] [Pubmed]
Speiser D.E., Valmori D., Rimoldi D., Pittet M.J., Liénard D., Cerundolo V., MacDonald H.R., Cerottini J.C., Romero P., 1999. CD28-negative cytolytic effector T cells frequently express NK receptors and are present at variable proportions in circulating lymphocytes from healthy donors and melanoma patients. European journal of immunology 29(6) pp. 1990-1999. [DOI] [Web of Science] [Pubmed]
Valmori D., Fonteneau J.F., Valitutti S., Gervois N., Dunbar R., Liénard D., Rimoldi D., Cerundolo V., Jotereau F., Cerottini J.C., Speiser D.E., Romero P., 1999. Optimal activation of tumor-reactive T cells by selected antigenic peptide analogues. International immunology 11(12) pp. 1971-80. [DOI] [Web of Science] [Pubmed]
Valmori D., Gileadi U., Servis C., Dunbar P.R., Cerottini J.C., Romero P., Cerundolo V., Lévy F., 1999. Modulation of proteasomal activity required for the generation of a cytotoxic T lymphocyte-defined peptide derived from the tumor antigen MAGE-3. Journal of Experimental Medicine 189(6) pp. 895-906. [DOI] [Web of Science] [Pubmed]
Valmori D., Pittet M.J., Rimoldi D., Liénard D., Dunbar R., Cerundolo V., Lejeune F., Cerottini J.C., Romero P., 05-1999. An antigen-targeted approach to adoptive transfer therapy of cancer. Cancer Research 59(9) pp. 2167-2173. [Web of Science] [Pubmed]
Valmori D., Pittet M.J., Vonarbourg C., Rimoldi D., Liénard D., Speiser D., Dunbar R., Cerundolo V., Cerottini J.C., Romero P., 1999. Analysis of the cytolytic T lymphocyte response of melanoma patients to the naturally HLA-A*0201-associated tyrosinase peptide 368-376. Cancer research 59(16) pp. 4050-5. [Web of Science] [Pubmed]
Velin D., Fotopoulos G., Kraehenbuhl J.P., Acha-Orbea H., 1999. Systemic antibodies can inhibit mouse mammary tumor virus-driven superantigen response in mucosa-associated lymphoid tissues. Journal of Virology 73(2) pp. 1729-1733. [Web of Science] [Pubmed]
Wilson A., Capone M., MacDonald H.R., 1999. Unexpectedly late expression of intracellular CD3epsilon and TCR gammadelta proteins during adult thymus development. International Immunology 11(10) pp. 1641-1650. [DOI] [Web of Science] [Pubmed]
1998
Bachmann M. F., Speiser D. E., Zakarian A., Ohashi P. S., 10-1998. Inhibition of TCR triggering by a spectrum of altered peptide ligands suggests the mechanism for TCR antagonism. European Journal of Immunology 28(10) pp. 3110-9. [Web of Science] [Pubmed]
Bachmann M. F., Waterhouse P., Speiser D. E., McKall-Faienza K., Mak T. W., Ohashi P. S., 01-1998. Normal responsiveness of CTLA-4-deficient anti-viral cytotoxic T cells. Journal of Immunology 160(1) pp. 95-100. [Web of Science] [Pubmed]
Beutner U., MacDonald H.R., 1998. TCR-MHC class II interaction is required for peripheral expansion of CD4 cells in a T cell-deficient host. International Immunology 10(3) pp. 305-310. [DOI] [Web of Science] [Pubmed]
Bour H., Horvath C., Lurquin C., Cerottini J.C., MacDonald H.R., 1998. Differential requirement for CD4 help in the development of an antigen-specific CD8+ T cell response depending on the route of immunization. Journal of immunology 160(11) pp. 5522-5529. [Web of Science] [Pubmed]
Brawand P., Biasi G., Horvath C., Cerottini J.C., MacDonald H.R., 1998. Flow-microfluorometric monitoring of oligoclonal CD8+ T cell responses to an immunodominant Moloney leukemia virus-encoded epitope in vivo. Journal of immunology 160(4) pp. 1659-1665. [Web of Science] [Pubmed]
Burns K., Martinon F., Esslinger C., Pahl H., Schneider P., Bodmer J.L., Di Marco F., French L., Tschopp J., 1998. MyD88, an adapter protein involved in interleukin-1 signaling. Journal of Biological Chemistry 273(20) pp. 12203-12209. [DOI] [Web of Science] [Pubmed]
Cerottini J. C., Valmori D., Rimoldi D., Romero P., 1998. Human tumor immunotherapy. New opportunities as well as new challenges. Advances in Experimental Medicine and Biology 451 pp. 247-50. [Web of Science] [Pubmed]
Chidgey A.P., Pircher H., MacDonald H.R., Boyd R.L., 1998. An adult thymic stromal-cell suspension model for in vitro positive selection. Developmental Immunology 6(3-4) pp. 157-170. [Pubmed]
D'Souza S., Rimoldi D., Lienard D., Lejeune F., Cerottini J. C., Romero P., 12-1998. Circulating Melan-A/Mart-1 specific cytolytic T lymphocyte precursors in HLA-A2+ melanoma patients have a memory phenotype. International Journal of Cancer 78(6) pp. 699-706. [Web of Science] [Pubmed]
Esslinger C.W., Jongeneel C.V., MacDonald H.R., 1998. Survival-independent function of NF-kappaB/Rel during late stages of thymocyte differentiation. Molecular immunology 35(13) pp. 847-852. [DOI] [Web of Science] [Pubmed]
Ferrero I, Anjuère F, Azcoitia I, Renno T, MacDonald HR Ardavin C, 1998. Viral superantigen-induced negative selection of TCR transgenic CD4+ CD8+ thymocytes depends on activation, but not proliferation. Blood 91 pp. 4248-4254.
Ferrero I., Anjuère F., Azcoitia I., Renno T., MacDonald H.R., Ardavín C., 1998. Viral superantigen-induced negative selection of TCR transgenic CD4+ CD8+ thymocytes depends on activation, but not proliferation. Blood 91(11) pp. 4248-4254. [Web of Science] [Pubmed]
Finke D., Mortezavi L., Acha-Orbea H., 1998. Preactivation of B lymphocytes does not enhance mouse mammary tumor virus infection. Journal of Virology 72(9) pp. 7688-7691. [Web of Science] [Pubmed]
Fleischhauer K., Zino E., Arevalo-Herrera M., Herrera S., Valmori D., Cerottini J. C., Benazzi E., Bordignon C., Romero P., 02-1998. Differential expression of HLA-A*02 subtypes in Colombian Blacks and Mestizos. Tissue Antigens 51(2) pp. 204-9. [Web of Science] [Pubmed]
Griffiths E., Ong H., Soloski M. J., Bachmann M. F., Ohashi P. S., Speiser D. E., 10-1998. Tumor defense by murine cytotoxic T cells specific for peptide bound to nonclassical MHC class I. Cancer Research 58(20) pp. 4682-7. [Web of Science] [Pubmed]
Hahne M., Kataoka T., Schröter M., Hofmann K., Irmler M., Bodmer J.L., Schneider P., Bornand T., Holler N., French L.E., Sordat B., Rimoldi D., Tschopp J., 1998. APRIL, a new ligand of the tumor necrosis factor family, stimulates tumor cell growth. Journal of Experimental Medicine 188(6) pp. 1185-1190. [Pubmed]
Hahne M., Kataoka T., Schröter M., Hofmann K., Irmler M., Bodmer J.L., Schneider P., Bornand T., Holler N., French L.E., Sordat B., Rimoldi D., Tschopp J., 1998. APRIL, a new ligand of the tumor necrosis factor family, stimulates tumor cell growth. Journal of Experimental Medicine 188(6) pp. 1185-1190. [DOI] [Web of Science] [Pubmed]
Heumann D., Lengacher S., Le Roy D., Jongeneel C. V., Glauser M. P., 1998. The pathogenic role of LBP in gram-negative sepsis and septic shock. Progress in Clinical and Biological Research 397 pp. 379-86. [Web of Science] [Pubmed]
Hozumi K., Tanaka Y., Sato T., Wilson A., Habu S., 1998. Evidence of stage-specific element for germ-line transcription of the TCR alpha gene located upstream of J alpha49 locus. European Journal of Immunology 28(4) pp. 1368-1378. [Pubmed]
Hudrisier D., Kessler B., Valitutti S., Horvath C., Cerottini J.C., Luescher I.F., 1998. The efficiency of antigen recognition by CD8+ CTL clones is determined by the frequency of serial TCR engagement. Journal of immunology 161(2) pp. 553-62. [Web of Science] [Pubmed]
Keilholz U., Willhauck M., Rimoldi D., Brasseur F., Dummer W., Rass K., de Vries T., Blaheta J., Voit C., Lethé B., Burchill S., 1998. Reliability of reverse transcription-polymerase chain reaction (RT-PCR)-based assays for the detection of circulating tumour cells: a quality-assurance initiative of the EORTC Melanoma Cooperative Group. European Journal of Cancer 34(5) pp. 750-753. [Pubmed]
Kessler B., Hudrisier D., Schroeter M., Tschopp J., Cerottini J.C., Luescher I.F., 1998. Peptide modification or blocking of CD8, resulting in weak TCR signaling, can activate CTL for Fas- but not perforin-dependent cytotoxicity or cytokine production. Journal of immunology 161(12) pp. 6939-6946. [Web of Science] [Pubmed]
MacDonald R.H., Lees R.K., Held W., 1998. Developmentally regulated extinction of Ly-49 receptor expression permits maturation and selection of NK1.1+ T cells. The Journal of experimental medicine 187(12) pp. 2109-2114. [Pubmed]
Maillard I., Launois P., Xenarios I., Louis J.A., Acha-Orbea H., Diggelmann H., 1998. Immune response to mouse mammary tumor virus in mice lacking the alpha/beta interferon or the gamma interferon receptor. Journal of Virology 72(4) pp. 2638-2646. [Web of Science] [Pubmed]
Maillard I., Xenarios I., Diggelmann H., Orbea H.A., 1998. Differential reactivity of TCR Vbeta10 alleles to a mouse mammary tumor virus superantigen. European Journal of Immunology 28(10) pp. 3075-3085. [DOI] [Web of Science] [Pubmed]
Marazzi S., Blum S., Hartmann R., Gundersen D., Schreyer M., Argraves S., von Fliedner V., Pytela R., Rüegg C., 1998. Characterization of human fibroleukin, a fibrinogen-like protein secreted by T lymphocytes. Journal of Immunology 161(1) pp. 138-147. [Web of Science] [Pubmed]
Oddo M., Renno T., Attinger A., Bakker T., MacDonald H.R., Meylan P.R., 1998. Fas ligand-induced apoptosis of infected human macrophages reduces the viability of intracellular Mycobacterium tuberculosis. Journal of immunology 160(11) pp. 5448-5454. [Web of Science] [Pubmed]
Ogg G. S., Rod Dunbar P., Romero P., Chen J. L., Cerundolo V., 09-1998. High frequency of skin-homing melanocyte-specific cytotoxic T lymphocytes in autoimmune vitiligo. Journal of Experimental Medicine 188(6) pp. 1203-8. [DOI] [Web of Science] [Pubmed]
Poyet J.L., Hoeveler A., Jongeneel C.V., 12-1998. Analysis of active site residues of the antiviral protein from summer leaves from Phytolacca americana by site-directed mutagenesis. Biochemical and Biophysical Research Communications 253(3) pp. 582-587. [DOI] [Web of Science] [Pubmed]
Renno T., Attinger A., Rimoldi D., Hahne M., Tschopp J., MacDonald H.R., 1998. Expression of B220 on activated T cell blasts precedes apoptosis. European journal of immunology 28(2) pp. 540-547. [DOI] [Web of Science] [Pubmed]
Robson MacDonald H., Lees R.K., Held W., 1998. Developmentally regulated extinction of Ly-49 receptor expression permits maturation and selection of NK1.1+ T cells. The Journal of Experimental Medicine 187(12) pp. 2109-2114. [Web of Science] [Pubmed]
Romero P., Cerottini J. C., Waanders G. A., 07-1998. Novel methods to monitor antigen-specific cytotoxic T-cell responses in cancer immunotherapy. Molecular Medicine Today 4(7) pp. 305-12. [DOI] [Web of Science] [Pubmed]
Romero P., Dunbar P. R., Valmori D., Pittet M., Ogg G. S., Rimoldi D., Chen J. L., Lienard D., Cerottini J. C., Cerundolo V., 11-1998. Ex vivo staining of metastatic lymph nodes by class I major histocompatibility complex tetramers reveals high numbers of antigen-experienced tumor-specific cytolytic T lymphocytes. Journal of Experimental Medicine 188(9) pp. 1641-50. [DOI] [Web of Science] [Pubmed]
Saldinger P.F., Porta N., Launois P., Louis J.A., Waanders G.A., Bouzouréne H., Michetti P., Blum A.L., Corthésy-Theulaz I.E., 1998. Immunization of BALB/c mice with Helicobacter urease B induces a T helper 2 response absent in Helicobacter infection. Gastroenterology 115(4) pp. 891-897. [DOI] [Web of Science] [Pubmed]
Schilham M.W., Wilson A., Moerer P., Benaissa-Trouw B.J., Cumano A., Clevers H.C., 1998. Critical involvement of Tcf-1 in expansion of thymocytes. Journal of Immunology 161(8) pp. 3984-3991. [Pubmed]
Speiser D. E., Bachmann M. F., Soloski M. J., Forman J., Ohashi P. S., 09-1998. Alloreactive cytotoxic T cells recognize minor transplantation antigens presented by major histocompatibility complex class Ib molecules. Transplantation 66(5) pp. 646-50. [DOI] [Web of Science] [Pubmed]
Speiser D. E., Ohashi P. S., 03-1998. Activation of cytotoxic T cells by solid tumours? Cellular and Molecular Life Sciences 54(3) pp. 263-71. [DOI] [Web of Science] [Pubmed]
Toellner K.M., Luther S.A., Sze D.M., Choy R.K., Taylor D.R., MacLennan I.C., Acha-Orbea H., 1998. T helper 1 (Th1) and Th2 characteristics start to develop during T cell priming and are associated with an immediate ability to induce immunoglobulin class switching. The Journal of Experimental Medicine 187(8) pp. 1193-1204. [Web of Science] [Pubmed]
Toellner K.M., Luther S.A., Sze D.M., Choy R.K., Taylor D.R., MacLennan I.C., Acha-Orbea H., 1998. T helper 1 (Th1) and Th2 characteristics start to develop during T cell priming and are associated with an immediate ability to induce immunoglobulin class switching. Journal of Experimental Medicine 187(8) pp. 1193-1204. [DOI] [Web of Science] [Pubmed]
Valmori D., Fonteneau J.F., Lizana C.M., Gervois N., Liénard D., Rimoldi D., Jongeneel V., Jotereau F., Cerottini J.C., Romero P., 1998. Enhanced generation of specific tumor-reactive CTL in vitro by selected Melan-A/MART-1 immunodominant peptide analogues. Journal of Immunology 160(4) pp. 1750-1758. [Web of Science] [Pubmed]
Valmori D., Gervois N., Rimoldi D., Fonteneau J. F., Bonelo A., Lienard D., Rivoltini L., Jotereau F., Cerottini J. C., Romero P., 12-1998. Diversity of the fine specificity displayed by HLA-A*0201-restricted CTL specific for the immunodominant Melan-A/MART-1 antigenic peptide. Journal of Immunology 161(12) pp. 6956-62. [Web of Science] [Pubmed]
van Meerwijk J.P., Bianchi T., Marguerat S., MacDonald H.R., 1998. Thymic lineage commitment rather than selection causes genetic variations in size of CD4 and CD8 compartments. Journal of Immunology 160(8) pp. 3649-3654. [Web of Science] [Pubmed]
van Meerwijk J.P., Marguerat S., MacDonald H.R., 1998. Homeostasis limits the development of mature CD8+ but not CD4+ thymocytes. Journal of Immunology 160(6) pp. 2730-2734. [Web of Science] [Pubmed]
Wilson A., MacDonald H.R., 1998. A limited role for beta-selection during gamma delta T cell development. Journal of Immunology 161(11) pp. 5851-5854. [Web of Science] [Pubmed]
1997
Acha-Orbea H, 1997. Retrovirus-host interactions. The mouse mammary tumor virus model. Medicina (Buenos Aires) 57 (Suppl II) pp. 43-52.
Acha-Orbea H., 1997. The role of superantigens in resistance to retroviral infection. Trends in Microbiology 5(10) p. 385. [DOI] [Web of Science] [Pubmed]
Anjuère F., Kuznetsov D., Romero P., Cerottini J.C., Jongeneel C.V., Luescher I.F., 1997. Differential roles of T cell receptor alpha and beta chains in ligand binding among H-2Kd-restricted cytolytic T lymphocyte clones specific for a photoreactive Plasmodium berghei circumsporozoite peptide derivative. The Journal of biological chemistry 272(13) pp. 8505-8514. [DOI] [Web of Science] [Pubmed]
Ardavin C., Luthi F., Andersson M., Scarpellino L., Martin P., Diggelmann H., Acha-Orbea H., 1997. Retrovirus-induced target cell activation in the early phases of infection: the mouse mammary tumor virus model. Journal of Virology 71(10) pp. 7295-7299. [Web of Science] [Pubmed]
Bachmann M. F., Kundig T. M., Speiser D. E., McKall-Faienza K., Kishara K., Mak T. W., Ohashi P. S., 01-1997. T-cell-independent antiviral B cell responses in CD45-deficient mice. Cellular Immunology 175(1) pp. 12-5. [DOI] [Web of Science] [Pubmed]
Bachmann M. F., Mariathasan S., Bouchard D., Speiser D. E., Ohashi P. S., 12-1997. Four types of Ca2+ signals in naive CD8+ cytotoxic T cells after stimulation with T cell agonists, partial agonists and antagonists. European Journal of Immunology 27(12) pp. 3414-9. [DOI] [Web of Science] [Pubmed]
Bachmann M. F., McKall-Faienza K., Schmits R., Bouchard D., Beach J., Speiser D. E., Mak T. W., Ohashi P. S., 10-1997. Distinct roles for LFA-1 and CD28 during activation of naive T cells: adhesion versus costimulation. Immunity 7(4) pp. 549-57. [DOI] [Web of Science] [Pubmed]
Bachmann M. F., Ohteki T., Faienza K. M., Zakarian A., Kagi D., Speiser D. E., Ohashi P. S., 11-1997. Altered peptide ligands trigger perforin- rather than Fas-dependent cell lysis. Journal of Immunology 159(9) pp. 4165-70. [Web of Science] [Pubmed]
Bachmann M. F., Oxenius A., Speiser D. E., Mariathasan S., Hengartner H., Zinkernagel R. M., Ohashi P. S., 09-1997. Peptide-induced T cell receptor down-regulation on naive T cells predicts agonist/partial agonist properties and strictly correlates with T cell activation. European Journal of Immunology 27(9) pp. 2195-203. [DOI] [Web of Science] [Pubmed]
Bachmann M. F., Speiser D. E., Ohashi P. S., 08-1997. Functional management of an antiviral cytotoxic T-cell response. Journal of Virology 71(8) pp. 5764-8. [Web of Science] [Pubmed]
Beutner U., Launois P., Ohteki T., Louis J.A., MacDonald H.R., 1997. Natural killer-like T cells develop in SJL mice despite genetically distinct defects in NK1.1 expression and in inducible interleukin-4 production. European Journal of Immunology 27(4) pp. 928-934. [DOI] [Web of Science] [Pubmed]
Biasi G., Facchinetti A., Mezzalira S., MacDonald H.R., 1997. Selective lysis of activated cells in oncorna virus infection. Scandinavian Journal of Immunology 45(4) pp. 366-370. [DOI] [Web of Science] [Pubmed]
Bodmer J.L., Burns K., Schneider P., Hofmann K., Steiner V., Thome M., Bornand T., Hahne M., Schröter M., Becker K., Wilson A., French L.E., Browning J.L., MacDonald H.R., Tschopp J., 1997. TRAMP, a novel apoptosis-mediating receptor with sequence homology to tumor necrosis factor receptor 1 and Fas(Apo-1/CD95). Immunity 6(1) pp. 79-88. [DOI] [Web of Science] [Pubmed]
Bodmer JL, Burns K, Schneider P, Hofmann K, Steiner V, Thome M, Bornand T, Hahne M, Schröter M, Becker K, Wilson A, French LE, Browning JL, MacDonald HR, Tschopp J, 1997. TRAMP, a novel apoptosis-mediating receptor with sequence homology to tumor necrosis factor receptor 1 and Fas(Apo-1/CD95). Immunity 6 pp. 79-88.
Cerottini J. C., Liénard D., Romero P., 1997. A new era for human cancer immunology. The Immunologist 5 pp. 27-32.
Cerottini J. C., Tschopp J., 1997. New knowledge about T-cell cytotoxicity. Annals of Oncology 8 Suppl 2 pp. 75-8. [DOI] [Web of Science] [Pubmed]
Delneste Y., Jeannin P., Potier L., Romero P., Bonnefoy J. Y., 08-1997. N-acetyl-L-cysteine exhibits antitumoral activity by increasing tumor necrosis factor alpha-dependent T-cell cytotoxicity. Blood 90(3) pp. 1124-32. [Web of Science] [Pubmed]
Esslinger C., 1997. Tissue targeted inhibition of transcription factor NF-kappaB in T lymphocytes of transgenic mice. Université de Lausanne, Faculté de biologie et médecine, (dir.).
Esslinger C.W., Wilson A., Sordat B., Beermann F., Jongeneel C.V., 06-1997. Abnormal T lymphocyte development induced by targeted overexpression of IkappaB alpha. Journal of Immunology 158(11) pp. 5075-5078. [Web of Science] [Pubmed]
Ferrero I, Anjuère F, MacDonald HR, Ardavin C, 1997. In vitro negative selection of viral superantigen-reactive thymocytes by thymic dendritic cells. Blood 90 pp. 1943-1951.
Ferrero I., Anjuère F., MacDonald H.R., Ardavín C., 1997. In vitro negative selection of viral superantigen-reactive thymocytes by thymic dendritic cells. Blood 90(5) pp. 1943-1951. [Web of Science] [Pubmed]
French L.E., Wilson A., Hahne M., Viard I., Tschopp J., MacDonald H.R., 1997. Fas ligand expression is restricted to nonlymphoid thymic components in situ. Journal of immunology 159(5) pp. 2196-2202. [Web of Science] [Pubmed]
Hartmann RR, Rimoldi D, Lejeune FJ, Carrel S, 1997. Cell differentiation and cell-cycle alterations by tyrosine kinase inhibitors in human melanoma cells. Melanoma Res. 7 pp. S27-S33.
Irmler M, Thome M, Hahne M, Schneider P, Hofmann K, Steiner V, Bodmer JL, Schröter M, Burns K, Mattmann C, Rimoldi D, French LE, Tschopp J, 1997. Inhibition of death receptor signals by cellular FLIP. Nature 388 pp. 190-195.
Irmler M., Thome M., Hahne M., Schneider P., Hofmann K., Steiner V., Bodmer J.L., Schröter M., Burns K., Mattmann C., Rimoldi D., French L.E., Tschopp J., 1997. Inhibition of death receptor signals by cellular FLIP. Nature 388(6638) pp. 190-195. [Document] [DOI] [Web of Science] [Pubmed]
Kessler B., Hudrisier D., Cerottini J.C., Luescher I.F., 1997. Role of CD8 in aberrant function of cytotoxic T lymphocytes. The Journal of experimental medicine 186(12) pp. 2033-2038. [DOI] [Web of Science] [Pubmed]
Korver W, Roose J, Wilson A, Clevers H, 1997. The winged-helix transcription factor trident is expressed in actively dividing lymphocytes. Immunobiol. 198 pp. 157-161.
Krebs J, Wilson A, Kisielow P, 1997. Calmodulin-dependent protein kinase IV during T-cell development. Biochem. Biophys. Res. Communication 241 pp. 383-389.
Launois P, Maillard I, Pingel S, Swihart KG, Xénarios I, Acha-Orbea H, Diggelmann H, Locksley RM, MacDonald HR, Louis J, 1997. IL-4 rapidly produced by Vbeta4 Valpha8 CD4+ T cells instructs Th2 cell development and susceptibility to Leishmania major in BALB/c mice. Immunity 6 pp. 541-549.
Launois P., Maillard I., Pingel S., Swihart K.G., Xénarios I., Acha-Orbea H., Diggelmann H., Locksley R.M., MacDonald H.R., Louis J.A., 1997. IL-4 rapidly produced by V beta 4 V alpha 8 CD4+ T cells instructs Th2 development and susceptibility to Leishmania major in BALB/c mice. Immunity 6(5) pp. 541-549. [DOI] [Web of Science] [Pubmed]
Livák F., Wilson A., MacDonald H.R., Schatz D.G., 1997. Alpha beta lineage-committed thymocytes can be rescued by the gamma delta T cell receptor (TCR) in the absence of TCR beta chain. European Journal of Immunology 27(11) pp. 2948-2958. [DOI] [Web of Science] [Pubmed]
Luther S.A., Acha-Orbea H., 1997. Mouse mammary tumor virus: immunological interplays between virus and host. Advances in Immunology 65 pp. 139-243. [Web of Science] [Pubmed]
Luther S.A., Acha-Orbea H., 1997. Mouse mammary tumor virus: immunological interplays between virus and host. Advances in Immunology 65 pp. 139-243. [DOI] [Web of Science] [Pubmed]
Luther S.A., Gulbranson-Judge A., Acha-Orbea H., MacLennan I.C., 1997. B cell response and histology of a retroviral infection in vivo. Annals of the New York Academy of Sciences 815 pp. 465-466. [DOI] [Web of Science] [Pubmed]
Luther S.A., Gulbranson-Judge A., Acha-Orbea H., MacLennan I.C., 1997. Viral superantigen drives extrafollicular and follicular B cell differentiation leading to virus-specific antibody production. The Journal of Experimental Medicine 185(3) pp. 551-562. [Web of Science] [Pubmed]
Luther S.A., Gulbranson-Judge A., Acha-Orbea H., MacLennan I.C., 1997. Viral superantigen drives extrafollicular and follicular B cell differentiation leading to virus-specific antibody production. Journal of Experimental Medicine 185(3) pp. 551-562. [DOI] [Web of Science] [Pubmed]
Luther S.A., Maillard I., Luthi F., Scarpellino L., Diggelmann H., Acha-Orbea H., 1997. Early neutralizing antibody response against mouse mammary tumor virus: critical role of viral infection and superantigen-reactive T cells. Journal of Immunology 159(6) pp. 2807-2814. [Web of Science] [Pubmed]
Luther SA, Gulbranson-Judge A, Acha-Orbea H, MacLennan ICM, 1997. B cell response and histology of a retroviral infection in vivo. Annals of the New York Academy of Sciences 815 pp. 465-466.
MacDonald H.R., 1997. Development and function of natural killer 1+ T-cells. Biochemical Society transactions 25(2) pp. 696-699. [Web of Science] [Pubmed]
MacDonald HR, 1997. Development and function of natural killer 1+ T cells. Biochemical Society Transactions 25 pp. 696-699.
MacDonald HR, 1997. Valpha14 NKT cells. A novel lymphoid cell lineage. Japanese Journal of Cancer Research 88(10).
MacLennan I.C., Gulbranson-Judge A., Toellner K.M., Casamayor-Palleja M., Chan E., Sze D.M., Luther S.A., Orbea H.A., 1997. The changing preference of T and B cells for partners as T-dependent antibody responses develop. Immunological Reviews 156 pp. 53-66. [Web of Science] [Pubmed]
Maillard I., Luthi F., Acha-Orbea H., Diggelmann H., 1997. Role of the immune response induced by superantigens in the pathogenesis of microbial infections. Parasitology 115 Suppl pp. S67-S78. [DOI] [Web of Science] [Pubmed]
Maryanski J.L., Casanova J.L., Falk K., Gournier H., Jaulin C., Kourilsky P., Lemonnier F.A., Lüthy R., Rammensee H.G., Rötzschke O., Servis C., López J.A., 1997. The diversity of antigen-specific TCR repertoires reflects the relative complexity of epitopes recognized. Human Immunology 54(2) pp. 117-128. [Web of Science] [Pubmed]
Mertsching E., Wilson A., MacDonald H.R., Ceredig R., 1997. T cell receptor alpha gene rearrangement and transcription in adult thymic gamma delta cells. European Journal of Immunology 27(2) pp. 389-396. [DOI] [Web of Science] [Pubmed]
Reed D. S., Romero P., Rimoldi D., Cerottini J. C., Schaack J., Jongeneel C. V., 09-1997. Construction and characterization of a recombinant adenovirus directing expression of the MAGE-1 tumor-specific antigen. International Journal of Cancer 72(6) pp. 1045-55. [Web of Science] [Pubmed]
Romero P., Gervois N., Schneider J., Escobar P., Valmori D., Pannetier C., Steinle A., Wolfel T., Lienard D., Brichard V., van Pel A., Jotereau F., Cerottini J. C., 09-1997. Cytolytic T lymphocyte recognition of the immunodominant HLA-A*0201-restricted Melan-A/MART-1 antigenic peptide in melanoma. Journal of Immunology 159(5) pp. 2366-74. [Web of Science] [Pubmed]
Serdobova I., Pla M., Reichenbach P., Sperisen P., Ghysdael J., Wilson A., Freeman J., Nabholz M., 1997. Elf-1 contributes to the function of the complex interleukin (IL)-2-responsive enhancer in the mouse IL-2 receptor alpha gene. Journal of Experimental Medicine 185(7) pp. 1211-1221. [Pubmed]
Shimamura M, Ohteki T, Launois P, Garcia AM, MacDonald HR, 1997. Thymus-independent generation of NK1+ T cells in vitro from fetal liver precursors. Journal of Immunology 158 pp. 3682-3689.
Shimamura M., Ohteki T., Beutner U., MacDonald H.R., 1997. Lack of directed V alpha 14-J alpha 281 rearrangements in NK1+ T cells. European Journal of Immunology 27(6) pp. 1576-1579. [DOI] [Web of Science] [Pubmed]
Shimamura M., Ohteki T., Launois P., Garcia A.M., MacDonald H.R., 1997. Thymus-independent generation of NK1+ T cells in vitro from fetal liver precursors. Journal of Immunology 158(8) pp. 3682-3689. [Web of Science] [Pubmed]
Speiser D. E., Bachmann M. F., Frick T. W., McKall-Faienza K., Griffiths E., Pfeffer K., Mak T. W., Ohashi P. S., 06-1997. TNF receptor p55 controls early acute graft-versus-host disease. Journal of Immunology 158(11) pp. 5185-90. [Web of Science] [Pubmed]
Speiser D. E., Bachmann M. F., Shahinian A., Mak T. W., Ohashi P. S., 04-1997. Acute graft-versus-host disease without costimulation via CD28. Transplantation 63(7) pp. 1042-4. [DOI] [Web of Science] [Pubmed]
Speiser D. E., Hermans J., van Biezen A., Starobinski M., Jeannet M., Jacobsen N., Niederwieser D., Gratwohl A., Apperley J. F., 06-1997. Haploidentical family member transplants for patients with chronic myeloid leukaemia: a report of the Chronic Leukaemia Working Party of off European Group for Blood and Marrow Transplantation (EBMT). Bone Marrow Transplantation 19(12) pp. 1197-203. [DOI] [Web of Science] [Pubmed]
Speiser D. E., Lee S. Y., Wong B., Arron J., Santana A., Kong Y. Y., Ohashi P. S., Choi Y., 05-1997. A regulatory role for TRAF1 in antigen-induced apoptosis of T cells. Journal of Experimental Medicine 185(10) pp. 1777-83. [DOI] [Web of Science] [Pubmed]
Speiser D. E., Miranda R., Zakarian A., Bachmann M. F., McKall-Faienza K., Odermatt B., Hanahan D., Zinkernagel R. M., Ohashi P. S., 08-1997. Self antigens expressed by solid tumors Do not efficiently stimulate naive or activated T cells: implications for immunotherapy. Journal of Experimental Medicine 186(5) pp. 645-53. [DOI] [Web of Science] [Pubmed]
Vacheron S., Renno T., Acha-Orbea H., 1997. A highly sensitive in vitro infection assay to explore early stages of mouse mammary tumor virus infection. Journal of Virology 71(10) pp. 7289-7294. [Web of Science] [Pubmed]
Valmori D., Lienard D., Waanders G., Rimoldi D., Cerottini J. C., Romero P., 02-1997. Analysis of MAGE-3-specific cytolytic T lymphocytes in human leukocyte antigen-A2 melanoma patients. Cancer Research 57(4) pp. 735-41. [Web of Science] [Pubmed]
van Meerwijk J.P., Marguerat S., Lees R.K., Germain R.N., Fowlkes B.J., MacDonald H.R., 1997. Quantitative impact of thymic clonal deletion on the T cell repertoire. The Journal of Experimental Medicine 185(3) pp. 377-383. [DOI] [Web of Science] [Pubmed]
Waanders G. A., Rimoldi D., Lienard D., Carrel S., Lejeune F., Dietrich P. Y., Cerottini J. C., Romero P., 05-1997. Melanoma-reactive human cytotoxic T lymphocytes derived from skin biopsies of delayed-type hypersensitivity reactions induced by injection of an autologous melanoma cell line. Clinical Cancer Research 3(5) pp. 685-96. [Web of Science] [Pubmed]
Yeh W. C., Shahinian A., Speiser D., Kraunus J., Billia F., Wakeham A., de la Pompa J. L., Ferrick D., Hum B., Iscove N., Ohashi P., Rothe M., Goeddel D. V., Mak T. W., 11-1997. Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice. Immunity 7(5) pp. 715-25. [DOI] [Web of Science] [Pubmed]
1996
Acha-Orbea H, 1996. Superantigens of mouse mammary tumour virus : Implications for diabetes ? pp. 111-119 in Diabetes/Metabolism Reviews. John Wiley & Sons Ltd.
Ardavin C, Waanders G, Ferrero I, Anjuère F, Acha-Orbea H, MacDonald HR, 1996. Expression and presentation of endogenous mouse mammary tumor virus superantigens by thymic and splenic dendritic cells and B cells. Journal of Immunology 157 pp. 2789-2794.
Ardavín C., Waanders G., Ferrero I., Anjuère F., Acha-Orbea H., MacDonald H.R., 1996. Expression and presentation of endogenous mouse mammary tumor virus superantigens by thymic and splenic dendritic cells and B cells. Journal of Immunology 157(7) pp. 2789-2794. [Web of Science] [Pubmed]
Bachmann M. F., Sebzda E., Kundig T. M., Shahinian A., Speiser D. E., Mak T. W., Ohashi P. S., 09-1996. T cell responses are governed by avidity and co-stimulatory thresholds. European Journal of Immunology 26(9) pp. 2017-22. [DOI] [Web of Science] [Pubmed]
Carrel S., Schreyer M., Spagnoli G., Cerottini J. C., Rimoldi D., 07-1996. Monoclonal antibodies against recombinant-MAGE-1 protein identify a cross-reacting 72-kDa antigen which is co-expressed with MAGE-1 protein in melanoma cells. International Journal of Cancer 67(3) pp. 417-22. [DOI] [Web of Science] [Pubmed]
Cerottini J.C., Liénard D., Romero P., 1996. Recognition of tumor-associated antigens by T-lymphocytes: perspectives for peptide-based vaccines. Annals of Oncology 7(4) pp. 339-342. [Web of Science] [Pubmed]
Chvatchko Y, Valera S, Aubry JP, Renno T, Buell G, Bonnefoy JY, 1996. The involvement of an ATP-gated ion channel, P2x1, in thymocyte apoptosis. Immunity 5 pp. 275-283.
Ghislain M., Dohmen R. J., Levy F., Varshavsky A., 09-1996. Cdc48p interacts with Ufd3p, a WD repeat protein required for ubiquitin-mediated proteolysis in Saccharomyces cerevisiae. EMBO Journal 15(18) pp. 4884-99. [Web of Science] [Pubmed]
Grégoire C., Lin S.Y., Mazza G., Rebai N., Luescher I.F., Malissen B., 1996. Covalent assembly of a soluble T cell receptor-peptide-major histocompatibility class I complex. Proceedings of the National Academy of Sciences of the United States of America 93(14) pp. 7184-7189. [DOI] [Web of Science] [Pubmed]
Hahne M., Renno T., Schroeter M., Irmler M., French L., Bornard T., MacDonald H.R., Tschopp J., 1996. Activated B cells express functional Fas ligand. European journal of immunology 26(3) pp. 721-724. [DOI] [Web of Science] [Pubmed]
Hahne M., Rimoldi D., Schröter M., Romero P., Schreier M., French L.E., Schneider P., Bornand T., Fontana A., Lienard D., Cerottini J., Tschopp J., 1996. Melanoma cell expression of Fas(Apo-1/CD95) ligand: implications for tumor immune escape. Science 274(5291) pp. 1363-1366. [DOI] [Web of Science] [Pubmed]
Herman J., van der Bruggen P., Luescher I.F., Mandruzzato S., Romero P., Thonnard J., Fleischhauer K., Boon T., Coulie P.G., 1996. A peptide encoded by the human MAGE3 gene and presented by HLA-B44 induces cytolytic T lymphocytes that recognize tumor cells expressing MAGE3. Immunogenetics 43(6) pp. 377-383. [DOI] [Web of Science] [Pubmed]
Jaeger E., Bernhard H., Romero P., Ringhoffer M., Arand M., Karbach J., Ilsemann C., Hagedorn M., Knuth A., 04-1996. Generation of cytotoxic T-cell responses with synthetic melanoma-associated peptides in vivo: implications for tumor vaccines with melanoma-associated antigens. International Journal of Cancer 66(2) pp. 162-9. [DOI] [Web of Science] [Pubmed]
Kessler B, Romero P, Luescher IF, 1996. Molecular principles of antigen recognition by cytotoxic R lymphocytes. pp. 15-28 in Actualités de chimie thérapeutique - 22ème série. Elsevier, Amsterdam,
Kessler B., Romero P., Luescher I. F., 1996. Molecular principles of antigen recognition by cytotoxic R lymphocytes. 15-28 p.
Krummenacher C., Diggelmann H., Acha-Orbea H., 1996. In vivo effects of a recombinant vaccinia virus expressing a mouse mammary tumor virus superantigen. Journal of Virology 70(5) pp. 3026-3031. [Web of Science] [Pubmed]
Levy F., Johnsson N., Rumenapf T., Varshavsky A., 05-1996. Using ubiquitin to follow the metabolic fate of a protein. Proceedings of the National Academy of Sciences of the United States of America 93(10) pp. 4907-12. [DOI] [Web of Science] [Pubmed]
Luescher I.F., Romero P., Kuznetsov D., Rimoldi D., Coulie P., Cerottini J.C., Jongeneel C.V., 1996. HLA photoaffinity labeling reveals overlapping binding of homologous melanoma-associated gene peptides by HLA-A1, HLA-A29, and HLA-B44. The Journal of biological chemistry 271(21) pp. 12463-12471. [DOI] [Web of Science] [Pubmed]
Luther S.A., Acha-Orbea H., 1996. Immune response to mouse mammary tumour virus. Current Opinion in Immunology 8(4) pp. 498-502. [DOI] [Web of Science] [Pubmed]
MacDonald H.R., 1996. Superantigens in disease. Springer Seminars in Immunopathology 17(4) pp. 283-284. [DOI] [Web of Science] [Pubmed]
Maillard I., Erny K., Acha-Orbea H., Diggelmann H., 1996. A V beta 4-specific superantigen encoded by a new exogenous mouse mammary tumor virus. European Journal of Immunology 26(5) pp. 1000-1006. [DOI] [Web of Science] [Pubmed]
Maryanski J.L., Jongeneel C.V., Bucher P., Casanova J.L., Walker P.R., 01-1996. Single-cell PCR analysis of TCR repertoires selected by antigen in vivo: a high magnitude CD8 response is comprised of very few clones. Immunity 4(1) pp. 47-55. [DOI] [Web of Science] [Pubmed]
Mulcahy K.A., Rimoldi D., Brasseur F., Rodgers S., Liénard D., Marchand M., Rennie I.G., Murray A.K., McIntyre C.A., Platts K.E., Leyvraz S., Boon T., Rees R.C., 1996. Infrequent expression of the MAGE gene family in uveal melanomas. International journal of cancer. Journal international du cancer 66(6) pp. 738-42. [DOI] [Web of Science] [Pubmed]
Ohteki T., MacDonald H.R., 1996. Stringent V beta requirement for the development of NK1.1+ T cell receptor-alpha/beta+ cells in mouse liver. The Journal of experimental medicine 183(3) pp. 1277-1282. [DOI] [Web of Science] [Pubmed]
Radtke F., Hug M., Georgiev O., Matsuo K., Schaffner W., 01-1996. Differential sensitivity of zinc finger transcription factors MTF-1, Sp1 and Krox-20 to CpG methylation of their binding sites. Biological Chemistry Hoppe-Seyler 377(1) pp. 47-56. [Pubmed]
Regan J., Monteiro F., Speiser D., Kalil J., Pouletty P., Buelow R., 07-1996. Pretransplant rejection risk assessment through enzyme-linked immunosorbent assay analysis of anti-HLA class I antibodies. American Journal of Kidney Diseases 28(1) pp. 92-8. [DOI] [Web of Science] [Pubmed]
Renard V., Delon J., Luescher I.F., Malissen B., Vivier E., Trautmann A., 1996. The CD8 beta polypeptide is required for the recognition of an altered peptide ligand as an agonist. European journal of immunology 26(12) pp. 2999-3007. [DOI] [Web of Science] [Pubmed]
Renard V., Romero P., Vivier E., Malissen B., Luescher I.F., 1996. CD8 beta increases CD8 coreceptor function and participation in TCR-ligand binding. The Journal of experimental medicine 184(6) pp. 2439-4244. [DOI] [Web of Science] [Pubmed]
Renno T., Acha-Orbea H., 1996. Superantigens in autoimmune diseases: still more shades of gray. Immunological Reviews 154 pp. 175-191. [DOI] [Web of Science] [Pubmed]
Renno T., Hahne M., Tschopp J., MacDonald H.R., 1996. Peripheral T cells undergoing superantigen-induced apoptosis in vivo express B220 and upregulate Fas and Fas ligand. The Journal of experimental medicine 183(2) pp. 431-437. [DOI] [Web of Science] [Pubmed]
Renno T., Hahne M., Tschopp J., MacDonald H.R., 1996. Peripheral T cells undergoing superantigen-induced apoptosis in vivo express B220 and upregulate Fas and Fas ligand. Journal of Experimental Medicine 183(2) pp. 431-437. [Web of Science] [Pubmed]
Romero P., 1996. Cytolytic T lymphocyte responses of cancer patients to tumor-associated antigens. Springer Seminars in Immunopathology 18(2) pp. 185-98. [DOI] [Web of Science] [Pubmed]
Speiser D. E., Loliger C. C., Siren M. K., Jeannet M., 06-1996. Pretransplant cytotoxic donor T-cell activity specific to patient HLA class I antigens correlating with mortality after unrelated BMT. British Journal of Haematology 93(4) pp. 935-9. [Web of Science] [Pubmed]
Speiser D. E., Sebzda E., Ohteki T., Bachmann M. F., Pfeffer K., Mak T. W., Ohashi P. S., 12-1996. Tumor necrosis factor receptor p55 mediates deletion of peripheral cytotoxic T lymphocytes in vivo. European Journal of Immunology 26(12) pp. 3055-60. [DOI] [Web of Science] [Pubmed]
Speiser D. E., Tiercy J. M., Rufer N., Grundschober C., Gratwohl A., Chapuis B., Helg C., Loliger C. C., Siren M. K., Roosnek E., Jeannet M., 05-1996. High resolution HLA matching associated with decreased mortality after unrelated bone marrow transplantation. Blood 87(10) pp. 4455-62. [Web of Science] [Pubmed]
Svensson K., Levy F., Sundberg U., Boman H. G., Hendil K. B., Kvist S., 04-1996. Proteasomes generate in vitro a natural peptide of influenza-A nucleoprotein functional in HLA-B27 antigen assembly. International Immunology 8(4) pp. 467-78. [DOI] [Web of Science] [Pubmed]
Velin D., Acha-Orbea H., Kraehenbuhl J.P., 1996. The neonatal Fc receptor is not required for mucosal infection by mouse mammary tumor virus. Journal of Virology 70(10) pp. 7250-7254. [Web of Science] [Pubmed]
Walker PR, Wilson A, Bucher P, Maryanski JL, 1996. Memory TCR repertoires analysed long-term reflect those selected during the primary response. International Immunology 8(7) pp. 1131-1138.
Zarour H., De Smet C., Lehmann F., Marchand M., Lethe B., Romero P., Boon T., Renauld J. C., 07-1996. The majority of autologous cytolytic T-lymphocyte clones derived from peripheral blood lymphocytes of a melanoma patient recognize an antigenic peptide derived from gene Pmel17/gp100. Journal of Investigative Dermatology 107(1) pp. 63-7. [DOI] [Web of Science] [Pubmed]
1995
Acha-Orbea H., MacDonald H.R., 1995. Superantigens of mouse mammary tumor virus. Annual Review of Immunology 13 pp. 459-486. [DOI] [Web of Science] [Pubmed]
Albrecht H., Schook L. B., Jongeneel C. V., 1995. Nuclear migration of NF-kappa B correlates with TNF-alpha mRNA accumulation. Journal of Inflammation 45(1) pp. 64-71. [Web of Science] [Pubmed]
Anjuère F., Horvath C., Cerottini J.C., Luescher I.F., 1995. Induction of CTL in vivo by major histocompatibility complex class I-peptide complexes covalently associated on the cell surface. European journal of immunology 25(6) pp. 1535-1540. [DOI] [Web of Science] [Pubmed]
Anjuère F., Layer A., Cerottini J.C., Servis C., Luescher I.F., 1995. Synthesis of a radioiodinated photoreactive MAGE-1 peptide derivative and photoaffinity labeling of cell-associated human leukocyte antigen-A1 molecules. Analytical biochemistry 229(1) pp. 61-67. [DOI] [Web of Science] [Pubmed]
Braun M.Y., Jouvin-Marche E., Marche P.N., MacDonald H.R., Acha-Orbea H., 1995. T cell receptor V beta repertoire in mice lacking endogenous mouse mammary tumor provirus. European Journal of Immunology 25(3) pp. 857-862. [DOI] [Web of Science] [Pubmed]
Buchmüller-Rouiller Y., Corrandin S.B., Smith J., Schneider P., Ransijn A., Jongeneel C.V., Mauël J., 1995. Role of glutathione in macrophage activation: effect of cellular glutathione depletion on nitrite production and leishmanicidal activity. Cellular Immunology 164(1) pp. 73-80. [DOI] [Web of Science] [Pubmed]
Déglon N., Wilson A., Desponds C., Laurent P., Bron C., Fasel N., 1995. Fatty acids regulate Thy-1 antigen mRNA stability in T lymphocyte precursors. European Journal of Biochemistry 231(3) pp. 687-696. [DOI] [Web of Science] [Pubmed]
Held W., Roland J., Raulet D. H., 07-1995. Allelic exclusion of Ly49-family genes encoding class I MHC-specific receptors on NK cells. Nature 376(6538) pp. 355-8. [DOI] [Web of Science] [Pubmed]
Irmler M., Hertig S., MacDonald H.R., Sadoul R., Becherer J.D., Proudfoot A., Solari R., Tschopp J., 1995. Granzyme A is an interleukin 1 beta-converting enzyme. The Journal of experimental medicine 181(5) pp. 1917-1922. [DOI] [Web of Science] [Pubmed]
Jongeneel C.V., 07-1995. Transcriptional regulation of the tumor necrosis factor alpha gene. Immunobiology 193(2-4) pp. 210-216. [Web of Science] [Pubmed]
Jongeneel C.V., Beutler B., 1995. Genetic polymorphism in the human TNF region: correlation or causation? Journal of Inflammation 46(1) pp. iii-ivi. [Pubmed]
Launois P., Ohteki T., Swihart K., MacDonald H.R., Louis J.A., 1995. In susceptible mice, Leishmania major induce very rapid interleukin-4 production by CD4+ T cells which are NK1.1-. European Journal of Immunology 25(12) pp. 3298-3307. [DOI] [Web of Science] [Pubmed]
Lengacher S., Jongeneel C. V., Le Roy D., Lee J. D., Kravchenko V., Ulevitch R. J., Glauser M. P., Heumann D., 1995. Reactivity of murine and human recombinant LPS-binding protein (LBP) within LPS and gram negative bacteria. Journal of Inflammation 47(4) pp. 165-72. [Web of Science] [Pubmed]
Lisby S., Muller K. M., Jongeneel C. V., Saurat J. H., Hauser C., 03-1995. Nickel and skin irritants up-regulate tumor necrosis factor-alpha mRNA in keratinocytes by different but potentially synergistic mechanisms. International Immunology 7(3) pp. 343-52. [DOI] [Web of Science] [Pubmed]
Luescher I.F., Anjuère F., Peitsch M.C., Jongeneel C.V., Cerottini J.C., Romero P., 07-1995. Structural analysis of TCR-ligand interactions studied on H-2Kd-restricted cloned CTL specific for a photoreactive peptide derivative. Immunity 3(1) pp. 51-63. [DOI] [Web of Science] [Pubmed]
Luescher I.F., Vivier E., Layer A., Mahiou J., Godeau F., Malissen B., Romero P., 1995. CD8 modulation of T-cell antigen receptor-ligand interactions on living cytotoxic T lymphocytes. Nature 373(6512) pp. 353-356. [DOI] [Web of Science] [Pubmed]
MacDonald H.R., 1995. NK1.1+ T cell receptor-alpha/beta+ cells: new clues to their origin, specificity, and function. The Journal of experimental medicine 182(3) pp. 633-638. [DOI] [Web of Science] [Pubmed]
MacDonald H.R., Bommhardt U., Cerottini J.C., 05-1995. Developmentally regulated expression of P-glycoprotein (multidrug resistance) activity in mouse thymocytes. European journal of immunology 25(5) pp. 1457-1460. [DOI] [Web of Science] [Pubmed]
Nabholz M., Soldaini E., Sperisen P., Pla M., Wang S.M., MacDonald H.R., Reichenbach P., Beermann F., Bucher P., 1995. The cis-acting elements controlling mouse IL-2R alpha transcription. Immunobiology 193(2-4) pp. 259-262. [Web of Science] [Pubmed]
Radtke F., Georgiev O., Muller H. P., Brugnera E., Schaffner W., 06-1995. Functional domains of the heavy metal-responsive transcription regulator MTF-1. Nucleic Acids Research 23(12) pp. 2277-86. [Pubmed]
Renno T., Hahne M., MacDonald H.R., 1995. Proliferation is a prerequisite for bacterial superantigen-induced T cell apoptosis in vivo. The Journal of experimental medicine 181(6) pp. 2283-2287. [DOI] [Web of Science] [Pubmed]
Romero P., Pannetier C., Herman J., Jongeneel C. V., Cerottini J. C., Coulie P. G., 10-1995. Multiple specificities in the repertoire of a melanoma patient's cytolytic T lymphocytes directed against tumor antigen MAGE-1.A1. Journal of Experimental Medicine 182(4) pp. 1019-28. [DOI] [Web of Science] [Pubmed]
Rosat J.P., Conceiçao-Silva F., Waanders G.A., Beermann F., Wilson A., Owen M.J., Hayday A.C., Huang S., Aguet M., MacDonald H.R., 1995. Expansion of gamma delta+ T cells in BALB/c mice infected with Leishmania major is dependent upon Th2-type CD4+ T cells. Infection and Immunity 63(8) pp. 3000-3004. [Web of Science] [Pubmed]
Rufer N., Tiercy J. M., Breur-Vriesendorp B., Gauchat-Feiss D., Shi X., Slavcev A., Lardy N., Speiser D., Gratwohl A., Chapuis B., Jeannet M., Roosnek E., 11-1995. Histoincompatibilities in ABDR-matched unrelated donor recipient combinations. Bone Marrow Transplantation 16(5) pp. 641-6. [Pubmed]
Soldaini E., Pla M., Beermann F., Espel E., Corthésy P., Barangé S., Waanders G.A., MacDonald H.R., Nabholz M., 1995. Mouse interleukin-2 receptor alpha gene expression. Delimitation of cis-acting regulatory elements in transgenic mice and by mapping of DNase-I hypersensitive sites. The Journal of biological chemistry 270(18) pp. 10733-10742. [DOI] [Web of Science] [Pubmed]
Verbeek S., Izon D., Hofhuis F., Robanus-Maandag E., te Riele H., van de Wetering M., Oosterwegel M., Wilson A., MacDonald H.R., Clevers H., 1995. An HMG-box-containing T-cell factor required for thymocyte differentiation. Nature 374(6517) pp. 70-74. [DOI] [Web of Science] [Pubmed]
Waanders G.A., Lees R.K., Held W., MacDonald H.R., 1995. Quantitation of endogenous mouse mammary tumor virus superantigen expression by lymphocyte subsets. European journal of immunology 25(9) pp. 2632-2637. [DOI] [Web of Science] [Pubmed]
Walker P.R., Ohteki T., Lopez J.A., MacDonald H.R., Maryanski J.L., 1995. Distinct phenotypes of antigen-selected CD8 T cells emerge at different stages of an in vivo immune response. Journal of immunology 155(7) pp. 3443-3452. [Web of Science] [Pubmed]
Wan M., Heuchel R., Radtke F., Hunziker P. E., Kagi J. H., 06-1995. Regulation of metallothionein gene expression in Cd- or Zn-adapted RK-13 cells. Experientia 51(6) pp. 606-11. [Pubmed]
Wilson A., MacDonald H.R., Malissen B., 1995. Expression of genes encoding the pre-TCR and CD3 complex during thymus development. International immunology 7(10) pp. 1659-1664. [DOI] [Web of Science] [Pubmed]
1994
Bazzoni F., Kruys V., Shakhov A., Jongeneel C. V., Beutler B., 01-1994. Analysis of tumor necrosis factor promoter responses to ultraviolet light. Journal of Clinical Investigation 93(1) pp. 56-62. [DOI] [Web of Science] [Pubmed]
Blum S., Milesi R., Tratkiewicz J., Olive D., Gallati H., Cerottini J. C., von Fliedner V., 06-1994. Rapid induction of cytolytic T cells via CD28 stimulation for cellular immunotherapy. Therapeutic Immunology 1(3) pp. 143-52. [Pubmed]
Bommhardt U., Cerottini J. C., MacDonald H. R., 12-1994. Heterogeneity in P-glycoprotein (multidrug resistance) activity among murine peripheral T cells: correlation with surface phenotype and effector function. European Journal of Immunology 24(12) pp. 2974-81. [DOI] [Web of Science] [Pubmed]
Boon T., Cerottini J. C., Van den Eynde B., van der Bruggen P., Van Pel A., 1994. Tumor antigens recognized by T lymphocytes. Annual Review of Immunology 12 pp. 337-65. [DOI] [Web of Science] [Pubmed]
Brugnera E., Georgiev O., Radtke F., Heuchel R., Baker E., Sutherland G. R., Schaffner W., 08-1994. Cloning, chromosomal mapping and characterization of the human metal-regulatory transcription factor MTF-1. Nucleic Acids Research 22(15) pp. 3167-73. [Pubmed]
Claeys D., Karapetian O., Saraga E., Schreyer M., Louis J., Acha-Orbea H., Blum A.L., Kraehenbuhl J.P., 1994. Mouse mammary tumor virus superantigens and murine autoimmune gastritis. Gastroenterology 107(4) pp. 924-933. [Web of Science] [Pubmed]
da Conceicao-Silva F., Perlaza B. L., Louis J. A., Romero P., 11-1994. Leishmania major infection in mice primes for specific major histocompatibility complex class I-restricted CD8+ cytotoxic T cell responses. European Journal of Immunology 24(11) pp. 2813-7. [DOI] [Web of Science] [Pubmed]
Gaugler B., Van den Eynde B., van der Bruggen P., Romero P., Gaforio J. J., De Plaen E., Lethe B., Brasseur F., Boon T., 03-1994. Human gene MAGE-3 codes for an antigen recognized on a melanoma by autologous cytolytic T lymphocytes. Journal of Experimental Medicine 179(3) pp. 921-30. [DOI] [Web of Science] [Pubmed]
Held W., Acha-Orbea H., MacDonald H.R., Waanders G.A., 1994. Superantigens and retroviral infection: insights from mouse mammary tumor virus. Immunology Today 15(4) pp. 184-190. [DOI] [Web of Science] [Pubmed]
Held W., Waanders G.A., Acha-Orbea H., MacDonald H.R., 1994. Reverse transcriptase-dependent and -independent phases of infection with mouse mammary tumor virus: implications for superantigen function. Journal of Experimental Medicine 180(6) pp. 2347-2351. [DOI] [Web of Science] [Pubmed]
Held W., Waanders G.A., MacDonald H.R., Acha-Orbea H., 1994. MHC class II hierarchy of superantigen presentation predicts efficiency of infection with mouse mammary tumor virus. International Immunology 6(9) pp. 1403-1407. [DOI] [Web of Science] [Pubmed]
Jongeneel C. V., 1994. Regulation of the TNF alpha gene. Progress in Clinical and Biological Research 388 pp. 367-81. [Pubmed]
Karapetian O., Shakhov A.N., Kraehenbuhl J.P., Acha-Orbea H., 1994. Retroviral infection of neonatal Peyer's patch lymphocytes: the mouse mammary tumor virus model. Journal of Experimental Medicine 180(4) pp. 1511-1516. [DOI] [Web of Science] [Pubmed]
Luescher I.F., Cerottini J.C., Romero P., 1994. Photoaffinity labeling of the T cell receptor on cloned cytotoxic T lymphocytes by covalent photoreactive ligand. The Journal of biological chemistry 269(8) pp. 5574-5582. [Web of Science] [Pubmed]
Luther S., Shakhov A.N., Xenarios I., Haga S., Imai S., Acha-Orbea H., 1994. New infectious mammary tumor virus superantigen with V beta-specificity identical to staphylococcal enterotoxin B (SEB). European Journal of Immunology 24(8) pp. 1757-1764. [DOI] [Web of Science] [Pubmed]
MacDonald H.R., Acha-Orbea H., 1994. Diabetes. Superantigen as suspect. Nature 371(6495) pp. 283-284. [DOI] [Web of Science] [Pubmed]
Romero P., Cerottini J.C., Luescher I.F., 1994. Efficient in vivo induction of CTL by cell-associated covalent H-2Kd-peptide complexes. Journal of immunological methods 171(1) pp. 73-84. [DOI] [Web of Science] [Pubmed]
Rufer N., Breur-Vriesendorp B., Tiercy J. M., Gauchat-Feiss D., Shi X., Slavcev A., Lardy N., Chapuis B., Gratwohl A., Speiser D., Jeannet M., Roosnek E., 09-1994. HLA-B35-subtype mismatches in ABDR serologically matched unrelated donor-recipient pairs. Human Immunology 41(1) pp. 96-101. [DOI] [Web of Science] [Pubmed]
Schook L. B., Albrecht H., Gallay P., Jongeneel C. V., 10-1994. Cytokine regulation of TNF-alpha mRNA and protein production by unprimed macrophages from C57Bl/6 and NZW mice. Journal of Leukocyte Biology 56(4) pp. 514-20. [Web of Science] [Pubmed]
Speiser D. E., Jeannet M., Goumaz C., Tiercy J. M., 12-1994. HLA-DRB1 matched kidneys are preferentially HLA-A and -B compatible and survive longer. Transplant Immunology 2(4) pp. 350-2. [Pubmed]
Speiser D. E., Tiercy J. M., Rufer N., Chapuis B., Morell A., Kern M., Gmur J., Gratwohl A., Roosnek E., Jeannet M., 06-1994. Relation between the resolution of HLA-typing and the chance of finding an unrelated bone marrow donor. Bone Marrow Transplantation 13(6) pp. 805-9. [Web of Science] [Pubmed]
Speiser D.E., Wyler C.A., Siegrist C.A., 06-1994. HIV-1 in newborns. New England Journal of Medicine 330(26) pp. 1905-1906. [DOI] [Web of Science] [Pubmed]
Tiercy J. M., Djavad N., Rufer N., Speiser D. E., Jeannet M., Roosnek E., 11-1994. Oligotyping of HLA-A2, -A3, and -B44 subtypes. Detection of subtype incompatibilities between patients and their serologically matched unrelated bone marrow donors. Human Immunology 41(3) pp. 207-15. [DOI] [Web of Science] [Pubmed]
Wilson A., Held W., MacDonald H.R., 1994. Two waves of recombinase gene expression in developing thymocytes. The Journal of experimental medicine 179(4) pp. 1355-1360. [DOI] [Web of Science] [Pubmed]
1993
Acha-Orbea H., 1993. Anti-T-cell receptor V beta antibodies in autoimmunity. Immunology Series 59 pp. 193-202. [Pubmed]
Acha-Orbea H., 1993. Bacterial and viral superantigens: roles in autoimmunity? Annals of the Rheumatic Diseases 52 Suppl 1 pp. S6-16. [DOI] [Web of Science] [Pubmed]
Acha-Orbea H., 1993. Roles of superantigens in microbial infections? Research in Immunology 144(3) pp. 198-201; discussion 214-22. [DOI] [Web of Science] [Pubmed]
Acha-Orbea H., 1993. T-cell receptors in autoimmune disease. Immunology Series 59 pp. 131-142. [Pubmed]
Acha-Orbea H., Held W., Waanders G.A., Shakhov A.N., Scarpellino L., Lees R.K., MacDonald H.R., 1993. Exogenous and endogenous mouse mammary tumor virus superantigens. Immunological Reviews 131(1) pp. 5-25. [DOI] [Web of Science] [Pubmed]
Acha-Orbea H., MacDonald H.R., 1993. Subversion of host immune responses by viral superantigens. Trends in Microbiology 1(1) pp. 32-34. [DOI] [Pubmed]
Båvik C.O., Lévy F., Hellman U., Wernstedt C., Eriksson U., 09-1993. The retinal pigment epithelial membrane receptor for plasma retinol-binding protein. Isolation and cDNA cloning of the 63-kDa protein. Journal of Biological Chemistry 268(27) pp. 20540-20546. [Web of Science] [Pubmed]
Beghdadi-Rais C., Schreyer M., Rousseaux M., Borel P., Eisenberg R.J., Cohen G.H., Bron C., Fasel N., 1993. Carboxyl terminus structural requirements for glycosyl-phosphatidylinositol anchor addition to cell surface proteins. Journal of Cell Science 105(3) pp. 831-840. [Web of Science] [Pubmed]
Beris P., Darbellay R., Speiser D., Kirchner V., Miescher P. A., 03-1993. De novo initiation codon mutation (ATG-->ACG) of the beta-globin gene causing beta-thalassemia in a Swiss family. American Journal of Hematology 42(3) pp. 248-53. [DOI] [Web of Science] [Pubmed]
Casanova J.L., Martinon F., Gournier H., Barra C., Pannetier C., Regnault A., Kourilsky P., Cerottini J.C., Maryanski J.L., 1993. T cell receptor selection by and recognition of two class I major histocompatibility complex-restricted antigenic peptides that differ at a single position. Journal of Experimental Medicine 177(3) pp. 811-820. [DOI] [Web of Science] [Pubmed]
Cerottini J. C., 01-1993. Actualites lausannoises de cancerologie. [Current aspects of oncology in Lausanne]. Revue Médicale de la Suisse Romande 113(1) pp. 7-8. [Pubmed]
Eberl G., Sabbatini A., Servis C., Romero P., Maryanski J. L., Corradin G., 11-1993. MHC class I H-2Kd-restricted antigenic peptides: additional constraints for the binding motif. International Immunology 5(11) pp. 1489-92. [DOI] [Web of Science] [Pubmed]
Franzeck U. K., Haselbach P., Speiser D., Bollinger A., 02-1993. Microangiopathy of cutaneous blood and lymphatic capillaries in chronic venous insufficiency (CVI). Yale Journal of Biology and Medicine 66(1) pp. 37-46. [Web of Science] [Pubmed]
Frick T. W., Speiser D. E., Bimmler D., Largiader F., 1993. Drug-induced acute pancreatitis: further criticism. Digestive Diseases 11(2) pp. 113-32. [DOI] [Web of Science] [Pubmed]
Gallay P., Jongeneel C.V., Barras C., Burnier M., Baumgartner J.D., Glauser M.P., Heumann D., 06-1993. Short time exposure to lipopolysaccharide is sufficient to activate human monocytes. Journal of Immunology 150(11) pp. 5086-5093. [Web of Science] [Pubmed]
Hauser C., Orbea H.A., 1993. Superantigens and their role in immune-mediated disease. Journal of Investigative Dermatology 101(4) pp. 503-505. [DOI] [Web of Science] [Pubmed]
Held W., Shakhov A.N., Izui S., Waanders G.A., Scarpellino L., MacDonald H.R., Acha-Orbea H., 1993. Superantigen-reactive CD4+ T cells are required to stimulate B cells after infection with mouse mammary tumor virus. Journal of Experimental Medicine 177(2) pp. 359-366. [DOI] [Web of Science] [Pubmed]
Held W., Waanders G.A., Shakhov A.N., Scarpellino L., Acha-Orbea H., MacDonald H.R., 1993. Superantigen-induced immune stimulation amplifies mouse mammary tumor virus infection and allows virus transmission. Cell 74(3) pp. 529-540. [DOI] [Web of Science] [Pubmed]
Jeannet M., Tiercy J. M., Roosnek E., Speiser D., 06-1993. HLA and bone marrow transplantation: techniques and strategy for tissue typing. Nouvelle Revue Française d'Hématologie 35(3) pp. 273-4. [Web of Science] [Pubmed]
Kvist S., Levy F., 04-1993. Early events in the assembly of MHC class I antigens. Seminars in Immunology 5(2) pp. 105-16. [DOI] [Pubmed]
Kyburz D., Aichele P., Speiser D. E., Hengartner H., Zinkernagel R. M., Pircher H., 08-1993. T cell immunity after a viral infection versus T cell tolerance induced by soluble viral peptides. European Journal of Immunology 23(8) pp. 1956-62. [DOI] [Web of Science] [Pubmed]
Kyburz D., Speiser D. E., Aebischer T., Hengartner H., Zinkernagel R. M., 06-1993. Virus-specific cytotoxic T cell-mediated lysis of lymphocytes in vitro and in vivo. Journal of Immunology 150(11) pp. 5051-8. [Web of Science] [Pubmed]
Kyburz D., Speiser D. E., Battegay M., Hengartner H., Zinkernagel R. M., 07-1993. Lysis of infected cells in vivo by antiviral cytolytic T cells demonstrated by release of cell internal viral proteins. European Journal of Immunology 23(7) pp. 1540-5. [DOI] [Web of Science] [Pubmed]
Lambert J.F., Acha-Orbea H., Kolb E., Diggelmann H., 1993. The 3' half of the mouse mammary tumor virus orf gene is not sufficient for its superantigen function in transgenic mice. Molecular Immunology 30(16) pp. 1399-1404. [DOI] [Web of Science] [Pubmed]
Maryanski J. L., Luthy R., Romero P., Healy F., Drouet C., Casanova J. L., Jaulin C., Kourilsky P., Corradin G., 04-1993. The interaction of antigenic peptides with the H-2Kd MHC class I molecule. Seminars in Immunology 5(2) pp. 95-104. [DOI] [Pubmed]
Parish N.M., Acha-Orbea H., Simpson E., Qin S.X., Lund T., Cooke A., 1993. A comparative study of T-cell receptor V beta usage in non-obese diabetic (NOD) and I-E transgenic NOD mice. Immunology 78(4) pp. 606-610. [Web of Science] [Pubmed]
Peitsch M. C., Jongeneel C. V., 02-1993. A 3-D model for the CD40 ligand predicts that it is a compact trimer similar to the tumor necrosis factors. International Immunology 5(2) pp. 233-8. [DOI] [Web of Science] [Pubmed]
Pociot F., Briant L., Jongeneel C. V., Molvig J., Worsaae H., Abbal M., Thomsen M., Nerup J., Cambon-Thomsen A., 01-1993. Association of tumor necrosis factor (TNF) and class II major histocompatibility complex alleles with the secretion of TNF-alpha and TNF-beta by human mononuclear cells: a possible link to insulin-dependent diabetes mellitus. European Journal of Immunology 23(1) pp. 224-31. [DOI] [Web of Science] [Pubmed]
Radtke F., Heuchel R., Georgiev O., Hergersberg M., Gariglio M., Dembic Z., Schaffner W., 04-1993. Cloned transcription factor MTF-1 activates the mouse metallothionein I promoter. EMBO Journal 12(4) pp. 1355-62. [Pubmed]
Romero P., Maryanski J.L., Luescher I.F., 1993. Photoaffinity labeling of the T cell receptor on living cytotoxic T lymphocytes. Journal of immunology 150(9) pp. 3825-3831. [Web of Science] [Pubmed]
Roosnek E., Hogendijk S., Zawadynski S., Speiser D., Tiercy J. M., Helg C., Chapuis B., Gratwohl A., Gmur J., Seger R., Jeannet M., 09-1993. The frequency of pretransplant donor cytotoxic T cell precursors with anti-host specificity predicts survival of patients transplanted with bone marrow from donors other than HLA-identical siblings. Transplantation 56(3) pp. 691-6. [DOI] [Web of Science] [Pubmed]
Rufer N., Breur-Vriesendorp B. S., Tiercy J. M., Slavcev A. S., Lardy N. M., Francis P., Kressig R., Speiser D. E., Helg C., Chapuis B., Gratwohl A., Jeannet M., Roosnek E., 11-1993. High-resolution histocompatibility testing of a group of sixteen B44-positive, ABDR serologically matched unrelated donor-recipient pairs. Analysis of serologically undisclosed incompatibilities by cellular techniques, isoelectrofocusing, and HLA oligotyping. Human Immunology 38(3) pp. 235-9. [DOI] [Web of Science] [Pubmed]
Rufer N., Tiercy J.M., Speiser D., Helg C., Gratwohl A., Chapuis B., Jeannet M., Roosnek E., 1993. Characterization of pretransplant CTL activity in "perfectly matched" unrelated bone marrow donor/recipient combinations. Bone Marrow Transplantation 11(Suppl. 1) pp. 20-23. [Web of Science] [Pubmed]
Shakhov A.N., Wang H., Acha-Orbea H., Pauley R.J., Wei W.Z., 1993. A new infectious mammary tumor virus in the milk of mice implanted with C4 hyperplastic alveolar nodules. European Journal of Immunology 23(11) pp. 2765-2769. [DOI] [Web of Science] [Pubmed]
Siegrist C. A., Wyler C. A., Gerritsen E. J., Perrin L., Speiser D., Suter S., 12-1993. Specific tolerance to HIV-1 antigens in an infant with rapid progression to AIDS. AIDS 7(12) pp. 1683-4. [DOI] [Web of Science] [Pubmed]
Tiercy J. M., Roosnek E., Speiser D., Cros P., Allibert P., Mach B., Jeannet M., 10-1993. Replacement of HLA class II serology by the HLA-DR microtitre plate oligotyping assay: a one-year experience in unrelated bone marrow donor selection. British Journal of Haematology 85(2) pp. 417-8. [DOI] [Web of Science] [Pubmed]
Waanders G.A., Shakhov A.N., Held W., Karapetian O., Acha-Orbea H., MacDonald H.R., 1993. Peripheral T cell activation and deletion induced by transfer of lymphocyte subsets expressing endogenous or exogenous mouse mammary tumor virus. Journal of Experimental Medicine 177(5) pp. 1359-1366. [DOI] [Web of Science] [Pubmed]
1992
Acha-Orbea H., 1992. Retroviral superantigens. Chemical Immunology 55 pp. 65-86. [Web of Science] [Pubmed]
Acha-Orbea H., Held W., Scarpellino L., Shakhov A.N., 1992. Mls: a link between immunology and retrovirology. International Reviews of Immunology 8(4) pp. 327-336. [Pubmed]
Acha-Orbea H., Scarpellino L., Shakhov A.N., Held W., MacDonald H.R., 1992. Inhibition of mouse mammary tumor virus-induced T cell responses in vivo by antibodies to an open reading frame protein. Journal of Experimental Medicine 176(6) pp. 1769-1772. [DOI] [Web of Science] [Pubmed]
Acha-Orbea H., Waanders G.A., Shakhov A.N., Held W., 1992. Infectious minor lymphocyte stimulating (Mls) antigens. Seminars in Immunology 4(5) pp. 297-303. [Pubmed]
Albrecht H., Shakhov A. N., Jongeneel C. V., 10-1992. trans activation of the tumor necrosis factor alpha promoter by the human T-cell leukemia virus type I Tax1 protein. Journal of Virology 66(10) pp. 6191-3. [Web of Science] [Pubmed]
Casanova J. L., Cerottini J. C., Matthes M., Necker A., Gournier H., Barra C., Widmann C., MacDonald H. R., Lemonnier F., Malissen B., Maryanski J.L, 08-1992. H-2-restricted cytolytic T lymphocytes specific for HLA display T cell receptors of limited diversity. Journal of Experimental Medicine 176(2) pp. 439-47. [DOI] [Web of Science] [Pubmed]
Cerottini J. C., von Fliedner V., Boon T., 01-1992. Recognition of tumor-associated antigens by T lymphocytes: from basic concepts to new approaches. Annals of Oncology 3(1) pp. 11-6. [Web of Science] [Pubmed]
Godeau F., Casanova J.L., Luescher I.F., Fairchild K.D., Delarbre C., Saucier C., Gachelin G., Kourilsky P., 1992. Binding of low concentration of peptide to H-2Kd produced in insect cells requires mouse beta 2-microglobulin co-expression. International immunology 4(2) pp. 265-275. [DOI] [Web of Science] [Pubmed]
Godeau F., Luescher I.F., Ojcius D.M., Saucier C., Mottez E., Cabanie L., Kourilsky P., 1992. Purification and ligand binding of a soluble class I major histocompatibility complex molecule consisting of the first three domains of H-2Kd fused to beta 2-microglobulin expressed in the baculovirus-insect cell system. The Journal of biological chemistry 267(34) pp. 24223-24229. [Web of Science] [Pubmed]
Held W., Shakhov A.N., Waanders G., Scarpellino L., Luethy R., Kraehenbuhl J.P., MacDonald H.R., Acha-Orbea H., 1992. An exogenous mouse mammary tumor virus with properties of Mls-1a (Mtv-7). Journal of Experimental Medicine 175(6) pp. 1623-1633. [DOI] [Web of Science] [Pubmed]
Jaulin C., Casanova J.L., Romero P., Luescher I., Cordey A.S., Maryanski J.L., Kourilsky P., 1992. Highly diverse T cell recognition of a single Plasmodium berghei peptide presented by a series of mutant H-2Kd molecules. Journal of immunology 149(12) pp. 3990-3994. [Web of Science] [Pubmed]
Jaulin C., Romero P., Luescher I.F., Casanova J.L., Prochnicka-Chalufour A., Langlade-Demoyen P., Maryanski J.L., Kourilsky P., 1992. Most residues on the floor of the antigen binding site of the class I MHC molecule H-2Kd influence peptide presentation. International immunology 4(8) pp. 945-953. [DOI] [Web of Science] [Pubmed]
Koh D.R., Fung-Leung W.P., Ho A., Gray D., Acha-Orbea H., Mak T.W., 1992. Less mortality but more relapses in experimental allergic encephalomyelitis in CD8-/- mice. Science 256(5060) pp. 1210-1213. [DOI] [Web of Science] [Pubmed]
López J.A., Luescher I.F., Cerottini J.C., 1992. Direct binding of peptides to MHC class I molecules on living cells. Analysis at the single cell level. Journal of immunology 149(12) pp. 3827-3835. [Web of Science] [Pubmed]
Luescher I.F., Lóez J.A., Malissen B., Cerottini J.C., 1992. Interaction of antigenic peptides with MHC class I molecules on living cells studied by photoaffinity labeling. Journal of immunology 148(4) pp. 1003-1011. [Web of Science] [Pubmed]
Pircher H., Rebai N., Groettrup M., Gregoire C., Speiser D. E., Happ M. P., Palmer E., Zinkernagel R. M., Hengartner H., Malissen B., 02-1992. Preferential positive selection of V alpha 2+ CD8+ T cells in mouse strains expressing both H-2k and T cell receptor V alpha a haplotypes: determination with a V alpha 2-specific monoclonal antibody. European Journal of Immunology 22(2) pp. 399-404. [DOI] [Web of Science] [Pubmed]
Rocken M., Muller K. M., Saurat J. H., Muller I., Louis J. A., Cerottini J. C., Hauser C., 01-1992. Central role for TCR/CD3 ligation in the differentiation of CD4+ T cells toward A Th1 or Th2 functional phenotype. Journal of Immunology 148(1) pp. 47-54. [Web of Science] [Pubmed]
Rodrigues M., Nussenzweig R. S., Romero P., Zavala F., 04-1992. The in vivo cytotoxic activity of CD8+ T cell clones correlates with their levels of expression of adhesion molecules. Journal of Experimental Medicine 175(4) pp. 895-905. [DOI] [Web of Science] [Pubmed]
Romero P., Eberl G., Casanova J.L., Cordey A.S., Widmann C., Luescher I.F., Corradin G., Maryanski J.L., 1992. Immunization with synthetic peptides containing a defined malaria epitope induces a highly diverse cytotoxic T lymphocyte response. Evidence that two peptide residues are buried in the MHC molecule. Journal of immunology 148(6) pp. 1871-1878. [Web of Science] [Pubmed]
Rothe H., Schuller I., Richter G., Jongeneel C. V., Kiesel U., Diamantstein T., Blankenstein T., Kolb H., 09-1992. Abnormal TNF production in prediabetic BB rats is linked to defective CD45R expression. Immunology 77(1) pp. 1-6. [Web of Science] [Pubmed]
Schneider R., Pircher H., Speiser D. E., Zinkernagel R., Hengartner H., 08-1992. Kinetics of clonal deletion varies with tolerizing antigen. Thymus 20(1) pp. 5-15. [Web of Science] [Pubmed]
Speiser D. E., Pircher H., Ohashi P. S., Kyburz D., Hengartner H., Zinkernagel R. M., 05-1992. Clonal deletion induced by either radioresistant thymic host cells or lymphohemopoietic donor cells at different stages of class I-restricted T cell ontogeny. Journal of Experimental Medicine 175(5) pp. 1277-83. [DOI] [Web of Science] [Pubmed]
Speiser D. E., Roosnek E., Jeannet M., Zinkernagel R. M., 04-1992. T-cell immunoincompetence in allogeneic chimerism. New England Journal of Medicine 326(15) pp. 1028-9. [Web of Science] [Pubmed]
Speiser D. E., Stubi U., Zinkernagel R. M., 01-1992. Extrathymic positive selection of alpha beta T-cell precursors in nude mice. Nature 355(6356) pp. 170-2. [DOI] [Web of Science] [Pubmed]
Traversari C., van der Bruggen P., Luescher I.F., Lurquin C., Chomez P., Van Pel A., De Plaen E., Amar-Costesec A., Boon T., 1992. A nonapeptide encoded by human gene MAGE-1 is recognized on HLA-A1 by cytolytic T lymphocytes directed against tumor antigen MZ2-E. The Journal of experimental medicine 176(5) pp. 1453-1457. [DOI] [Web of Science] [Pubmed]
von Fliedner V., Miescher S., Gerain J., Gallati H., Barras C., Heumann D., Cerottini J. C., 01-1992. Production of tumor necrosis factor-alpha by naive or memory T lymphocytes activated via CD28. Cellular Immunology 139(1) pp. 198-207. [DOI] [Web of Science] [Pubmed]
Widmann C., Romero P., Maryanski J. L., Corradin G., Valmori D., 10-1992. T helper epitopes enhance the cytotoxic response of mice immunized with MHC class I-restricted malaria peptides. Journal of Immunological Methods 155(1) pp. 95-9. [DOI] [Web of Science] [Pubmed]
1991
Acha-Orbea H., 1991. Limited heterogeneity of autoantigens and T cells in autoimmune diseases? Research in Immunology 142(5-6) pp. 487-490. [DOI] [Web of Science] [Pubmed]
Acha-Orbea H., Palmer E., 1991. Mls--a retrovirus exploits the immune system. Immunology Today 12(10) pp. 356-361. [DOI] [Web of Science] [Pubmed]
Acha-Orbea H., Scarpellino L., 1991. Nonobese diabetic and nonobese nondiabetic mice have unique MHC class II haplotypes. Immunogenetics 34(1) pp. 57-59. [DOI] [Web of Science] [Pubmed]
Acha-Orbea H., Shakhov A.N., Scarpellino L., Kolb E., Müller V., Vessaz-Shaw A., Fuchs R., Blöchlinger K., Rollini P., Billotte J., Sarafidou M., MacDonald H.R., Diggelmann H., 1991. Clonal deletion of V beta 14-bearing T cells in mice transgenic for mammary tumour virus. Nature 350(6315) pp. 207-211. [DOI] [Web of Science] [Pubmed]
Cerottini J.C., Luescher I.F., 1991. Direct analysis of peptide binding to cell-associated MHC class I molecules. Immunology letters 30(2) pp. 171-175. [DOI] [Web of Science] [Pubmed]
Drouet C., Shakhov A. N., Jongeneel C. V., 09-1991. Enhancers and transcription factors controlling the inducibility of the tumor necrosis factor-alpha promoter in primary macrophages. Journal of Immunology 147(5) pp. 1694-700. [Web of Science] [Pubmed]
Healy F., Drouet C., Romero P., Jaulin C., Maryanski J. L., 12-1991. Conversion of a self peptide sequence into a Kd-restricted neo-antigen by a Tyr substitution. Journal of Experimental Medicine 174(6) pp. 1657-60. [DOI] [Web of Science] [Pubmed]
Herrmann T., Romero P., Sartoris S., Paiola F., Accolla R. S., Maryanski J. L., MacDonald H. R., 04-1991. Staphylococcal enterotoxin-dependent lysis of MHC class II negative target cells by cytolytic T lymphocytes. Journal of Immunology 146(8) pp. 2504-12. [Web of Science] [Pubmed]
Jongeneel C. V., Briant L., Udalova I. A., Sevin A., Nedospasov S. A., Cambon-Thomsen A., 11-1991. Extensive genetic polymorphism in the human tumor necrosis factor region and relation to extended HLA haplotypes. Proceedings of the National Academy of Sciences of the United States of America 88(21) pp. 9717-21. [DOI] [Web of Science] [Pubmed]
Luescher I.F., Romero P., Cerottini J.C., Maryanski J.L., 1991. Specific binding of antigenic peptides to cell-associated MHC class I molecules. Nature 351(6321) pp. 72-74. [DOI] [Web of Science] [Pubmed]
Maryanski J. L., Romero P., Van Pel A., Boon T., Salemme F. R., Cerottini J. C., Corradin G., 10-1991. The identification of tyrosine as a common key residue in unrelated H-2Kd restricted antigenic peptides. International Immunology 3(10) pp. 1035-42. [DOI] [Web of Science] [Pubmed]
Rodrigues M. M., Cordey A. S., Arreaza G., Corradin G., Romero P., Maryanski J. L., Nussenzweig R. S., Zavala F., 06-1991. CD8+ cytolytic T cell clones derived against the Plasmodium yoelii circumsporozoite protein protect against malaria. International Immunology 3(6) pp. 579-85. [DOI] [Web of Science] [Pubmed]
Romero P., Corradin G., Luescher I.F., Maryanski J.L., 1991. H-2Kd-restricted antigenic peptides share a simple binding motif. The Journal of experimental medicine 174(3) pp. 603-612. [DOI] [Web of Science] [Pubmed]
Speiser D. E., Bollinger A., 02-1991. Microangiopathy in mild chronic venous incompetence (CVI): morphological alterations and increased transcapillary diffusion detected by fluorescence videomicroscopy. International Journal of Microcirculation; Clinical and Experimental 10(1) pp. 55-66. [Web of Science] [Pubmed]
Speiser D. E., Brandle R., Lees R. K., Schneider R., Zinkernagel R. M., MacDonald H. R., 02-1991. Neonatal tolerance to MIs-1a determinants: deletion or anergy of V beta 6+ T lymphocytes depending upon MHC compatibility of neonatally injected cells. International Immunology 3(2) pp. 127-34. [DOI] [Web of Science] [Pubmed]
Widmann C., Maryanski J. L., Romero P., Corradin G., 12-1991. Differential stability of antigenic MHC class I-restricted synthetic peptides. Journal of Immunology 147(11) pp. 3745-51. [Web of Science] [Pubmed]
1990
Acha-Orbea H., McDevitt H.O., 1990. The role of class II molecules in development of insulin-dependent diabetes mellitus in mice, rats and humans. Current Topics in Microbiology and Immunology 156 pp. 103-119. [Web of Science] [Pubmed]
Acha-Orbea H., Scarpellino L., Hertig S., Dupuis M., Tschopp J., 1990. Inhibition of lymphocyte mediated cytotoxicity by perforin antisense oligonucleotides. EMBO Journal 9(12) pp. 3815-3819. [Web of Science] [Pubmed]
Gabathuler R., Levy F., Kvist S., 08-1990. Requirements for the association of adenovirus type 2 E3/19K wild-type and mutant proteins with HLA antigens. Journal of Virology 64(8) pp. 3679-85. [Web of Science] [Pubmed]
Held W., MacDonald H.R., Mueller C., 1990. Expression of genes encoding cytotoxic cell-associated serine proteases in thymocytes. International immunology 2(1) pp. 57-62. [DOI] [Web of Science] [Pubmed]
Held W., MacDonald H.R., Weissman I.L., Hess M.W., Mueller C., 1990. Genes encoding tumor necrosis factor alpha and granzyme A are expressed during development of autoimmune diabetes. Proceedings of the National Academy of Sciences of the United States of America 87(6) pp. 2239-2243. [DOI] [Web of Science] [Pubmed]
Held W., Mueller C., MacDonald H.R., 1990. Expression of T cell receptor genes in the thymus: localization of transcripts in situ and comparison of mature and immature subsets. European journal of immunology 20(9) pp. 2133-2136. [DOI] [Web of Science] [Pubmed]
Jongeneel C.V., Acha-Orbea H., Blankenstein T., 1990. A polymorphic microsatellite in the tumor necrosis factor alpha promoter identifies an allele unique to the NZW mouse strain. Journal of Experimental Medicine 171(6) pp. 2141-2146. [DOI] [Web of Science] [Pubmed]
MacDonald H. R., Budd R. C., Cerottini J. C., 1990. Pgp-1 (Ly 24) as a marker of murine memory T lymphocytes. Current Topics in Microbiology and Immunology 159 pp. 97-109. [Web of Science] [Pubmed]
Romero P., Maryanski J. L., Cordey A. S., Corradin G., Nussenzweig R. S., Zavala F., 08-1990. Isolation and characterization of protective cytolytic T cells in a rodent malaria model system. Immunology Letters 25(1-3) pp. 27-31. [DOI] [Web of Science] [Pubmed]
Shakhov A. N., Collart M. A., Vassalli P., Nedospasov S. A., Jongeneel C. V., 01-1990. Kappa B-type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factor alpha gene in primary macrophages. Journal of Experimental Medicine 171(1) pp. 35-47. [DOI] [Web of Science] [Pubmed]
Shakhov A. N., Kuprash D. V., Azizov M. M., Jongeneel C. V., Nedospasov S. A., 11-1990. Structural analysis of the rabbit TNF locus, containing the genes encoding TNF-beta (lymphotoxin) and TNF-alpha (tumor necrosis factor). Gene 95(2) pp. 215-21. [DOI] [Web of Science] [Pubmed]
Speiser D. E., Zinkernagel R. M., 12-1990. Thymic MHC class I gene regulation of susceptibility to lymphocytic choriomeningitis. Thymus 16(3-4) pp. 187-93. [Web of Science] [Pubmed]
Speiser D. E., Zurcher T., Ramseier H., Hengartner H., Staeheli P., Haller O., Zinkernagel R. M., 03-1990. Nuclear myxovirus-resistance protein Mx is a minor histocompatibility antigen. Proceedings of the National Academy of Sciences of the United States of America 87(5) pp. 2021-5. [DOI] [Web of Science] [Pubmed]
Tsuji M., Romero P., Nussenzweig R. S., Zavala F., 11-1990. CD4+ cytolytic T cell clone confers protection against murine malaria. Journal of Experimental Medicine 172(5) pp. 1353-7. [DOI] [Web of Science] [Pubmed]
1989
Carrel S., Lamarre D., Isler P., Rapin C., Fleury S., Salvi S., Sekaly R. P., Cerottini J. C., 08-1989. A positive signal is transduced via surface CD4 molecules. Research in Immunology 140(5-6) pp. 545-61. [Web of Science] [Pubmed]
Cerottini J. C., 03-1989. Reponse immunitaire: aspects nouveaux. [Immune response: current aspects]. Revue Médicale de la Suisse Romande 109(3) pp. 201-3. [Pubmed]
Cerottini J. C., MacDonald H. R., 1989. The cellular basis of T-cell memory. Annual Review of Immunology 7 pp. 77-89. [DOI] [Web of Science] [Pubmed]
Heber-Katz E., Acha-Orbea H., 1989. The V-region disease hypothesis: evidence from autoimmune encephalomyelitis. Immunology Today 10(5) pp. 164-169. [DOI] [Web of Science] [Pubmed]
Jongeneel C. V., Bouvier J., Bairoch A., 01-1989. A unique signature identifies a family of zinc-dependent metallopeptidases. FEBS Letters 242(2) pp. 211-4. [DOI] [Web of Science] [Pubmed]
Jongeneel C. V., Quackenbush E. J., Ronco P., Verroust P., Carrel S., Letarte M., 02-1989. Common acute lymphoblastic leukemia antigen expressed on leukemia and melanoma cell lines has neutral endopeptidase activity. Journal of Clinical Investigation 83(2) pp. 713-7. [DOI] [Web of Science] [Pubmed]
Jongeneel C. V., Shakhov A. N., Nedospasov S. A., Cerottini J. C., 03-1989. Molecular control of tissue-specific expression at the mouse TNF locus. European Journal of Immunology 19(3) pp. 549-52. [Web of Science] [Pubmed]
MacDonald H. R., Speiser D., Lees R., Schneider R., Zinkernagel R. M., Hengartner H., 1989. Positive and negative selection of the T-cell antigen receptor repertoire in nontransgenic mice. Cold Spring Harbor Symposia on Quantitative Biology 54 Pt 1 pp. 129-33. [Pubmed]
Maryanski J. L., Abastado J. P., Corradin G., Cerottini J. C., 1989. Structural features of peptides recognized by H-2Kd-restricted T cells. Cold Spring Harbor Symposia on Quantitative Biology 54 Pt 1 pp. 545-50. [Pubmed]
Monod L., Diserens A. C., Jongeneel C. V., Carrel S., Ronco P., Verroust P., de Tribolet N., 11-1989. Human glioma cell lines expressing the common acute lymphoblastic leukemia antigen (cALLa) have neutral endopeptidase activity. International Journal of Cancer 44(5) pp. 948-51. [DOI] [Web of Science] [Pubmed]
Romero P., Beran M., Shtalrid M., Andersson B., Talpaz M., Blick M., 01-1989. Alternative 5' end of the bcr-abl transcript in chronic myelogenous leukemia. Oncogene 4(1) pp. 93-8. [Web of Science] [Pubmed]
Romero P., Maryanski J. L., Corradin G., Nussenzweig R. S., Nussenzweig V., Zavala F., 09-1989. Cloned cytotoxic T cells recognize an epitope in the circumsporozoite protein and protect against malaria. Nature 341(6240) pp. 323-6. [DOI] [Web of Science] [Pubmed]
Schneider R., Lees R., Pedrazzini T., Odermatt B., Speiser D. E., Zinkernagel R. M., Hengartner H., MacDonald H. R., 1989. Fate of potentially self-reactive T cells in neonatal mice: analysis of V beta 6+ T cells in Mlsa mice. Thymus 13(1-2) pp. 35-43. [Web of Science] [Pubmed]
Speiser D. E., Kolb E., Schneider R., Pircher H., Hengartner H., MacDonald H. R., Zinkernagel R. M., 1989. Tolerance to Mlsa by clonal deletion of V beta 6+ T cells in bone marrow and thymus chimeras. Thymus 13(1-2) pp. 27-33. [Web of Science] [Pubmed]
Speiser D. E., Lees R. K., Hengartner H., Zinkernagel R. M., MacDonald H. R., 12-1989. Positive and negative selection of T cell receptor V beta domains controlled by distinct cell populations in the thymus. Journal of Experimental Medicine 170(6) pp. 2165-70. [DOI] [Web of Science] [Pubmed]
Speiser D. E., Schneider R., Hengartner H., MacDonald H. R., Zinkernagel R. M., 08-1989. Clonal deletion of self-reactive T cells in irradiation bone marrow chimeras and neonatally tolerant mice. Evidence for intercellular transfer of Mlsa. Journal of Experimental Medicine 170(2) pp. 595-600. [DOI] [Web of Science] [Pubmed]
Unanue E. R., Cerottini J. C., 11-1989. Antigen presentation. FASEB Journal 3(13) pp. 2496-502. [Web of Science] [Pubmed]
1988
Carrel S., Moretta A., Pantaleo G., Tambussi G., Isler P., Perussia B., Cerottini J. C., 03-1988. Stimulation and proliferation of CD4+ peripheral blood T lymphocytes induced by an anti-CD4 monoclonal antibody. European Journal of Immunology 18(3) pp. 333-9. [DOI] [Web of Science] [Pubmed]
Cerottini J. C., Budd R. C., MacDonald H. R., 1988. Phenotypic identification of memory cytolytic T lymphocytes in a subset of Lyt-2+ cells. Annals of the New York Academy of Sciences 532 pp. 68-75. [DOI] [Web of Science] [Pubmed]
Goldhirsch A., Greiner R., Dreher E., Sessa C., Krauer F., Forni M., Jungi F.W., Brunner K.W., Veraguth P., Engeler V., Leyvraz S, Siegenthaler P, Gloor E, Buser K, Gelber RD, Cavalli F, 1988. Treatment of advanced ovarian cancer with surgery, chemotherapy, and consolidation of response by whole-abdominal radiotherapy. Cancer 62(1) pp. 40-47. [DOI] [Web of Science] [Pubmed]
Isler P., Salvi S., Rapin C., Giuffre L., Cerottini J. C., Carrel S., 10-1988. Antigen-independent activation of T cells mediated by a novel cell surface heterodimer (Tp135-145). European Journal of Immunology 18(10) pp. 1491-8. [DOI] [Web of Science] [Pubmed]
Jongeneel C. V., Nedospasov S. A., Plaetinck G., Naquet P., Cerottini J. C., 03-1988. Expression of the tumor necrosis factor locus is not necessary for the cytolytic activity of T lymphocytes. Journal of Immunology 140(6) pp. 1916-22. [Web of Science] [Pubmed]
Letarte M., Vera S., Tran R., Addis J. B., Onizuka R. J., Quackenbush E. J., Jongeneel C. V., McInnes R. R., 10-1988. Common acute lymphocytic leukemia antigen is identical to neutral endopeptidase. Journal of Experimental Medicine 168(4) pp. 1247-53. [DOI] [Web of Science] [Pubmed]
Louis J., Cerottini J. C., 1988. Reconnaissance des antigenes par les lymphocytes T et B. [Recognition of antigens by lymphocytes T and B]. Annales de Biologie Clinique 46(4) pp. 269-71. [Web of Science] [Pubmed]
MacDonald H.R., Schneider R., Lees R.K., Howe R.C., Acha-Orbea H., Festenstein H., Zinkernagel R.M., Hengartner H., 1988. T-cell receptor V beta use predicts reactivity and tolerance to Mlsa-encoded antigens. Nature 332(6159) pp. 40-45. [DOI] [Web of Science] [Pubmed]
Maryanski J. L., Pala P., Cerottini J. C., Corradin G., 04-1988. Synthetic peptides as antigens and competitors in recognition by H-2-restricted cytolytic T cells specific for HLA. Journal of Experimental Medicine 167(4) pp. 1391-405. [DOI] [Web of Science] [Pubmed]
Pala P., Bodmer H. C., Pemberton R. M., Cerottini J. C., Maryanski J. L., Askonas B. A., 10-1988. Competition between unrelated peptides recognized by H-2-Kd restricted T cells. Journal of Immunology 141(7) pp. 2289-94. [Web of Science] [Pubmed]
Pala P., Corradin G., Strachan T., Sodoyer R., Jordan B. R., Cerottini J. C., Maryanski J. L., 02-1988. Mapping of HLA epitopes recognized by H-2-restricted cytotoxic T lymphocytes specific for HLA using recombinant genes and synthetic peptides. Journal of Immunology 140(3) pp. 871-7. [Web of Science] [Pubmed]
Payne J., Huber B.T., Cannon N.A., Schneider R., Schilham M.W., Acha-Orbea H., MacDonald H.R., Hengartner H., 10-1988. Two monoclonal rat antibodies with specificity for the beta-chain variable region V beta 6 of the murine T-cell receptor. Proceedings of the National Academy of Sciences of the United States of America 85(20) pp. 7695-7698. [DOI] [Web of Science] [Pubmed]
Tschopp J., Jongeneel C. V., 04-1988. Cytotoxic T lymphocyte mediated cytolysis. Biochemistry 27(8) pp. 2641-6. [DOI] [Web of Science] [Pubmed]
1987
Budd R. C., Cerottini J. C., Horvath C., Bron C., Pedrazzini T., Howe R. C., MacDonald H. R., 05-1987. Distinction of virgin and memory T lymphocytes. Stable acquisition of the Pgp-1 glycoprotein concomitant with antigenic stimulation. Journal of Immunology 138(10) pp. 3120-9. [Web of Science] [Pubmed]
Budd R. C., Cerottini J. C., MacDonald H. R., 02-1987. Phenotypic identification of memory cytolytic T lymphocytes in a subset of Lyt-2+ cells. Journal of Immunology 138(4) pp. 1009-13. [Web of Science] [Pubmed]
Budd R. C., Cerottini J. C., MacDonald H. R., 06-1987. Selectively increased production of interferon-gamma by subsets of Lyt-2+ and L3T4+ T cells identified by expression of Pgp-1. Journal of Immunology 138(11) pp. 3583-6. [Web of Science] [Pubmed]
Carrel S., Isler P., Salvi S., Giuffrè L., Pantaleo G., Mach J.P., Cerottini J.C., 10-1987. Identification of a novel 45-kDa cell surface molecule involved in activation of the human Jurkat T cell line. European journal of immunology 17(10) pp. 1395-1402. [DOI] [Web of Science] [Pubmed]
Carrel S., Salvi S., Giuffre L., Isler P., Cerottini J. C., 06-1987. A novel 90-kDa polypeptide (Tp90) possibly involved in an antigen-independent pathway of T cell activation. European Journal of Immunology 17(6) pp. 835-41. [DOI] [Web of Science] [Pubmed]
Cerottini J. C., 07-1987. Lymphocytes: donnees recentes. [Lymphocytes: recent findings]. Schweizerische Medizinische Wochenschrift 117(29) pp. 1061-5. [Web of Science] [Pubmed]
Muller U., Jongeneel C. V., Nedospasov S. A., Lindahl K. F., Steinmetz M., 01-1987. Tumour necrosis factor and lymphotoxin genes map close to H-2D in the mouse major histocompatibility complex. Nature 325(6101) pp. 265-7. [DOI] [Web of Science] [Pubmed]
Patarroyo M. E., Romero P., Torres M. L., Clavijo P., Moreno A., Martinez A., Rodriguez R., Guzman F., Cabezas E., 08-1987. Induction of protective immunity against experimental infection with malaria using synthetic peptides. Nature 328(6131) pp. 629-32. [DOI] [Web of Science] [Pubmed]
Romero P., Heimer E. P., Herrera S., Felix A. M., Nussenzweig R. S., Zavala F., 09-1987. Antigenic analysis of the repeat domain of the circumsporozoite protein of Plasmodium vivax. Journal of Immunology 139(5) pp. 1679-82. [Web of Science] [Pubmed]
Semon D., Kawashima E., Jongeneel C. V., Shakhov A. N., Nedospasov S. A., 11-1987. Nucleotide sequence of the murine TNF locus, including the TNF-alpha (tumor necrosis factor) and TNF-beta (lymphotoxin) genes. Nucleic Acids Research 15(21) pp. 9083-4. [DOI] [Web of Science] [Pubmed]
Titus R. G., Milon G., Marchal G., Vassalli P., Cerottini J. C., Louis J. A., 10-1987. Involvement of specific Lyt-2+ T cells in the immunological control of experimentally induced murine cutaneous leishmaniasis. European Journal of Immunology 17(10) pp. 1429-33. [DOI] [Web of Science] [Pubmed]
1986
Budd R. C., Cerottini J. C., MacDonald H. R., 12-1986. Cultured Lyt-2- L3T4- T lymphocytes from normal thymus or lpr mice express a broad spectrum of cytolytic activity. Journal of Immunology 137(12) pp. 3734-41. [Web of Science] [Pubmed]
Engers H. D., Brunner K. T., Cerottini J. C., 1986. Cytolytic activity mediated by T lymphocytes. Methods in Enzymology 132 pp. 437-45. [Pubmed]
Gromkowski S. H., Brown T. C., Cerutti P. A., Cerottini J. C., 02-1986. DNA of human Raji target cells is damaged upon lymphocyte-mediated lysis. Journal of Immunology 136(3) pp. 752-6. [Web of Science] [Pubmed]
Lowenthal J. W., Cerottini J. C., MacDonald H. R., 08-1986. Interleukin 1-dependent induction of both interleukin 2 secretion and interleukin 2 receptor expression by thymoma cells. Journal of Immunology 137(4) pp. 1226-31. [Web of Science] [Pubmed]
MacDonald H.R., Blanc C., Lees R.K., Sordat B., 1986. Abnormal distribution of T cell subsets in athymic mice. Journal of Immunology 136(12) pp. 4337-4339. [Web of Science] [Pubmed]
Maryanski J. L., Pala P., Corradin G., Jordan B. R., Cerottini J. C., 12-1986. H-2-restricted cytolytic T cells specific for HLA can recognize a synthetic HLA peptide. Nature 324(6097) pp. 578-9. [DOI] [Web of Science] [Pubmed]
Milon G., Titus R. G., Cerottini J. C., Marchal G., Louis J. A., 02-1986. Higher frequency of Leishmania major-specific L3T4+ T cells in susceptible BALB/c as compared with resistant CBA mice. Journal of Immunology 136(4) pp. 1467-71. [Web of Science] [Pubmed]
Nedospasov S. A., Hirt B., Shakhov A. N., Dobrynin V. N., Kawashima E., Accolla R. S., Jongeneel C. V., 10-1986. The genes for tumor necrosis factor (TNF-alpha) and lymphotoxin (TNF-beta) are tandemly arranged on chromosome 17 of the mouse. Nucleic Acids Research 14(19) pp. 7713-25. [DOI] [Web of Science] [Pubmed]
Romero P., Blick M., Talpaz M., Murphy E., Hester J., Gutterman J., 03-1986. C-sis and C-abl expression in chronic myelogenous leukemia and other hematologic malignancies. Blood 67(3) pp. 839-41. [Web of Science] [Pubmed]
1985
Budd R. C., MacDonald H. R., Lowenthal J. W., Davignon J. L., Izui S., Cerottini J. C., 12-1985. Growth and differentiation in vitro of the accumulating Lyt-2-/L3T4- subset in lpr mice. Journal of Immunology 135(6) pp. 3704-11. [Web of Science] [Pubmed]
Davignon J. L., Budd R. C., Ceredig R., Piguet P. F., MacDonald H. R., Cerottini J. C., Vassalli P., Izui S., 10-1985. Functional analysis of T cell subsets from mice bearing the lpr gene. Journal of Immunology 135(4) pp. 2423-8. [Web of Science] [Pubmed]
MacDonald H. R., Bron C., Rousseaux M., Horvath C., Cerottini J. C., 05-1985. Production and characterization of monoclonal anti-Thy-1 antibodies that stimulate lymphokine production by cytolytic T cell clones. European Journal of Immunology 15(5) pp. 495-501. [DOI] [Web of Science] [Pubmed]
Maryanski J. L., Moretta A., Jordan B., De Plaen E., Van Pel A., Boon T., Cerottini J. C., 11-1985. Human T cell recognition of cloned HLA class I gene products expressed on DNA transfectants of mouse mastocytoma P815. European Journal of Immunology 15(11) pp. 1111-7. [DOI] [Web of Science] [Pubmed]
Shimonkevitz R., Cerottini J. C., MacDonald H. R., 1985. Requirement for Lyt-2/3 molecules on allospecific cytolytic T lymphocyte clones is dependent upon target cell antigen density. Advances in Experimental Medicine and Biology 184 pp. 343-53. [Web of Science] [Pubmed]
Titus R. G., Ceredig R., Cerottini J. C., Louis J. A., 09-1985. Therapeutic effect of anti-L3T4 monoclonal antibody GK1.5 on cutaneous leishmaniasis in genetically-susceptible BALB/c mice. Journal of Immunology 135(3) pp. 2108-14. [Web of Science] [Pubmed]
Troye-Blomberg M., Andersson G., Stoczkowska M., Shabo R., Romero P., Patarroyo M. E., Wigzell H., Perlmann P., 11-1985. Production of IL 2 and IFN-gamma by T cells from malaria patients in response to Plasmodium falciparum or erythrocyte antigens in vitro. Journal of Immunology 135(5) pp. 3498-504. [Web of Science] [Pubmed]
1984
Harris D. T., MacDonald H. R., Cerottini J. C., 01-1984. Antigen recognition by H-2-restricted cytolytic T lymphocytes is not mediated by two independent receptors. Journal of Experimental Medicine 159(1) pp. 330-5. [DOI] [Web of Science] [Pubmed]
Harris D. T., MacDonald H. R., Cerottini J. C., 01-1984. Direct transfer of antigen-specific cytolytic activity to noncytolytic cells upon fusion with liposomes derived from cytolytic T cell clones. Journal of Experimental Medicine 159(1) pp. 261-75. [DOI] [Web of Science] [Pubmed]
Kelso A., MacDonald H. R., Smith K. A., Cerottini J. C., Brunner K. T., 06-1984. Interleukin 2 enhancement of lymphokine secretion by T lymphocytes: analysis of established clones and primary limiting dilution microcultures. Journal of Immunology 132(6) pp. 2932-8. [Web of Science] [Pubmed]
Maryanski J. L., MacDonald H. R., Lees R. K., Sordat B., Cerottini J. C., 1984. Alloreactive cytolytic T lymphocyte precursor cells in aged C57Bl/6 nu/nu mice: frequency and cell surface phenotype. Experimental Cell Biology 52(1-2) pp. 21-4. [Web of Science] [Pubmed]
Moretta A., Pantaleo G., Mingari M. C., Melioli G., Moretta L., Cerottini J. C., 02-1984. Assignment of human natural killer (NK)-like cells to the T cell lineage. Single allospecific T cell clones lyse specific or NK-sensitive target cells via distinct recognition structures. European Journal of Immunology 14(2) pp. 121-5. [DOI] [Web of Science] [Pubmed]
Moretta A., Pantaleo G., Mingari M. C., Moretta L., Cerottini J. C., 03-1984. Clonal heterogeneity in the requirement for T3, T4, and T8 molecules in human cytolytic T lymphocyte function. Journal of Experimental Medicine 159(3) pp. 921-34. [DOI] [Web of Science] [Pubmed]
Sekaly R. P., MacDonald H. R., Nabholz M., Smith K. A., Cerottini J. C., 10-1984. Regulation of the rate of cell cycle progression in quiescent cytolytic T cells by T cell growth factor: analysis by flow microfluorometry. Journal of Cellular Physiology 121(1) pp. 159-66. [DOI] [Web of Science] [Pubmed]
1983
Kanagawa O., Louis J. A., Engers H. D., Cerottini J. C., 01-1983. Effect of sublethal whole-body irradiation on subsequent secondary cytolytic T cell responses in vitro. Journal of Immunology 130(1) pp. 24-8. [Web of Science] [Pubmed]
Mazingue C., Dessaint J. P., Schmitt-Verhulst A. M., Cerottini J. C., Capron A., 1983. Inhibition of cytotoxic T lymphocytes by a schistosome-derived inhibitory factor is independent of an inhibition of the production of interleukin 2. International Archives of Allergy and Applied Immunology 72(1) pp. 22-9. [DOI] [Web of Science] [Pubmed]
Moretta A., Mingari M. C., Cerottini J. C., Fauci A. S., Moretta L., 02-1983. Relationship between expression of Fc gamma receptors or Ia antigens and cytolytic activities of alloactivated human T cells. Clinical Immunology and Immunopathology 26(2) pp. 232-9. [DOI] [Web of Science] [Pubmed]
Moretta A., Pantaleo G., Moretta L., Cerottini J. C., Mingari M. C., 02-1983. Direct demonstration of the clonogenic potential of every human peripheral blood T cell. Clonal analysis of HLA-DR expression and cytolytic activity. Journal of Experimental Medicine 157(2) pp. 743-54. [DOI] [Web of Science] [Pubmed]
Moretta A., Pantaleo G., Moretta L., Mingari M. C., Cerottini J. C., 08-1983. Quantitative assessment of the pool size and subset distribution of cytolytic T lymphocytes within human resting or alloactivated peripheral blood T cell populations. Journal of Experimental Medicine 158(2) pp. 571-85. [DOI] [Web of Science] [Pubmed]
1982
Brunner K. T., Weiss A., Cerottini J. C., MacDonald H. R., 09-1982. Clonal analysis of the T lymphocyte response to murine sarcoma virus-induced tumors. Transplantation Proceedings 14(3) pp. 556-8. [Web of Science] [Pubmed]
Kanagawa O., Louis J., Cerottini J. C., 05-1982. Frequency and cross-reactivity od cytolytic T lymphocyte precursors reacting against male alloantigens. Journal of Immunology 128(5) pp. 2362-6. [Web of Science] [Pubmed]
Kelso A., Glasebrook A. L., Brunner K. T., Kanagawa O., Engers H. D., MacDonald H. R., Cerottini J. C., 1982. Production of macrophage activating factor by cytolytic and noncytolytic T lymphocyte clones. Advances in Experimental Medicine and Biology 155 pp. 493-8. [Web of Science] [Pubmed]
MacDonald H. R., Glasebrook A. L., Acuto O., Kelso A., Bron C., Cerottini J. C., 1982. Heterogeneity of inhibition of cytolytic T lymphocyte clones by monoclonal anti-Lyt-2/3 antibodies: parallel effects on cytolysis, proliferation and lymphokine secretion. Advances in Experimental Medicine and Biology 146 pp. 533-45. [Web of Science] [Pubmed]
MacDonald H. R., Glasebrook A. L., Cerottini J. C., 12-1982. Clonal heterogeneity in the functional requirement for Lyt-2/3 molecules on cytolytic T lymphocytes: analysis by antibody blocking and selective trypsinization. Journal of Experimental Medicine 156(6) pp. 1711-22. [DOI] [Web of Science] [Pubmed]
MacDonald H. R., Sekaly R. P., Kanagawa O., Thiernesse N., Taswell C., Cerottini J. C., Weiss A., Glasebrook A. L., Engers H. D., Kelso A., Brunner K. T., Bron C., 03-1982. Cytolytic T lymphocyte clones. Immunobiology 161(1-2) pp. 84-106. [Web of Science] [Pubmed]
Maryanski J. L., Van Snick J., Cerottini J. C., Boon T., 05-1982. Immunogenic variants obtained by mutagenesis of mouse mastocytoma P815. III. Clonal analysis of the syngeneic cytolytic T lymphocyte response. European Journal of Immunology 12(5) pp. 401-6. [DOI] [Web of Science] [Pubmed]
Moretta A., Accolla R. S., Cerottini J. C., 02-1982. IL-2-mediated T cell proliferation in humans is blocked by a monoclonal antibody directed against monomorphic determinants of HLA-DR antigens. Journal of Experimental Medicine 155(2) pp. 599-604. [DOI] [Web of Science] [Pubmed]
1981
Brunner K. T., MacDonald H. R., Cerottini J. C., 08-1981. Quantitation and clonal isolation of cytolytic T lymphocyte precursors selectively infiltrating murine sarcoma virus-induced tumors. Journal of Experimental Medicine 154(2) pp. 362-73. [DOI] [Web of Science] [Pubmed]
MacDonald H. R., Mach J. P., Schreyer M., Zaech P., Cerottini J. C., 03-1981. Flow cytofluorometric analysis of the binding of Vicia villosa lectin to T lymphoblasts: lack of correlation with cytolytic function. Journal of Immunology 126(3) pp. 883-6. [Web of Science] [Pubmed]
MacDonald H. R., Thiernesse N., Cerottini J. C., 05-1981. Inhibition of T cell-mediated cytolysis by monoclonal antibodies directed against Lyt-2: heterogeneity of inhibition at the clonal level. Journal of Immunology 126(5) pp. 1671-5. [Web of Science] [Pubmed]
Maryanski J. L., MacDonald H. R., Sordat B., Cerottini J. C., 12-1981. Cell surface phenotype of cytolytic T lymphocyte precursors in aged nude mice. European Journal of Immunology 11(12) pp. 968-72. [DOI] [Web of Science] [Pubmed]
Maryanski J. L., MacDonald H. R., Sordat B., Cerottini J. C., 03-1981. Cytolytic T lymphocyte precursor cells in congenitally athymic C57BL/6 nu/nu mice: quantitation, enrichment, and specificity. Journal of Immunology 126(3) pp. 871-6. [Web of Science] [Pubmed]
Moretta L., Mingari M. C., Sekaly P. R., Moretta A., Chapuis B., Cerottini J. C., 08-1981. Surface markers of cloned human T cells with various cytolytic activities. Journal of Experimental Medicine 154(2) pp. 569-74. [DOI] [Web of Science] [Pubmed]
Moretta L., Moretta A., Canonica G. W., Bacigalupo A., Mingari M. C., Cerottini J. C., 1981. Receptors for immunoglobulins on resting and activated human T cells. Immunological Reviews 56 pp. 141-62. [DOI] [Web of Science] [Pubmed]
Sekaly R. P., MacDonald H. R., Zaech P., Glasebrook A. L., Cerottini J. C., 08-1981. Cytolytic T lymphocyte function is independent of growth phase and position in the mitotic cycle. Journal of Experimental Medicine 154(2) pp. 575-80. [DOI] [Web of Science] [Pubmed]
1980
Chapuis B., Louis J., Barrelet L., Dialdas J., Dragon V., Cerottini J. C., 05-1980. Complexes antigene-anticorps circulants et cancer. [Circulating antibody complexes and cancer]. Schweizerische Medizinische Wochenschrift 110(21) pp. 796-801. [Web of Science] [Pubmed]
Degiovanni G., Cerottini J. C., Brunner K. T., 01-1980. Generation of cytolytic T lymphocytes in vitro. XI. Accessory cell requirement in secondary responses to particulate alloantigen. European Journal of Immunology 10(1) pp. 40-5. [DOI] [Web of Science] [Pubmed]
Dent P. B., Louis J. A., McCulloch P. B., Dunnett C. W., Cerottini J. C., 01-1980. Correlation of elevated C1q binding activity and carcinoembryonic antigen levels with clinical features and prognosis in bronchogenic carcinoma. Cancer 45(1) pp. 130-6. [DOI] [Web of Science] [Pubmed]
Ishiyama H., Louis J. A., Cerottini J. C., 03-1980. Polyclonal antibody synthesis and autoantibody formation in mice inoculated with murine sarcoma virus. Clinical Immunology and Immunopathology 15(3) pp. 456-64. [DOI] [Web of Science] [Pubmed]
MacDonald H. R., Cerottini J. C., Ryser J. E., Maryanski J. L., Taswell C., Widmer M. B., Brunner K. T., 1980. Quantitation and cloning of cytolytic T lymphocytes and their precursors. Immunological Reviews 51 pp. 93-123. [DOI] [Web of Science] [Pubmed]
1979
David A., Bernard J., Thiernesse N., Nicolas G., Cerottini J. C., Zagury D., 01-1979. Le processus d'exocytose lysosomale localisee est-il responsable de l'action cytolytique des lymphocytes T tuers? [Is the process of localized lysosomal exocytosis responsible for the cytolytic action of killer T-lymphocytes?]. Comptes Rendus des Seances de l'Academie des Sciences. Serie D, Sciences Naturelles 288(4) pp. 441-4. [Web of Science] [Pubmed]
Degiovanni G., Maryanski J. L., Cerottini J. C., Brunner K. T., 1979. Generation of cytolytic T lymphocytes in vitro. XII. Detection of memory CTL precursors in peripheral blood of alloimmune mice. Scandinavian Journal of Immunology 10(5) pp. 473-8. [DOI] [Web of Science] [Pubmed]
Dent P. B., Louis J. A., McCulloch P. B., Dunnett C. W., Cerottini J. C., 06-1979. Application of tumor marker analysis to patients with lung cancer. Schweizerische Medizinische Wochenschrift 109(22) pp. 827-30. [Web of Science] [Pubmed]
MacDonald H. R., Cerottini J. C., 06-1979. Inhibition of T cell-mediated cytolysis by 2-deoxy-D-glucose:dissociation of the inhibitory effect from glycoprotein synthesis. European Journal of Immunology 9(6) pp. 466-70. [DOI] [Web of Science] [Pubmed]
Maryanski J. L., Cerottini J. C., Brunner K. T., 01-1979. Generation of cytolytic T lymphocytes in vitro. X. Induction of primary and secondary CTL responses by the mitogen sodium periodate. Journal of Immunology 122(1) pp. 342-9. [Web of Science] [Pubmed]
Perussia B., Trinchieri G., Cerottini J. C., 03-1979. Analysis of human lymphocyte subpopulations responsible for antibody-dependent and spontaneous cell-mediated cytotoxicity. Transplantation Proceedings 11(1) pp. 793-5. [Web of Science] [Pubmed]
Perussia B., Trinchieri G., Cerottini J. C., 08-1979. Functional studies of Fc receptor-bearing human lymphocytes: effect of treatment with proteolytic enzymes. Journal of Immunology 123(2) pp. 681-7. [Web of Science] [Pubmed]
Trinchieri G., Perussia B., Santoli D., Cerottini J. C., 03-1979. Human natural killer cells. Transplantation Proceedings 11(1) pp. 807-10. [Web of Science] [Pubmed]
Zagury D., Bernard J., Jeannesson P., Thiernesse N., Cerottini J. C., 10-1979. Studies on the mechanism of T cell-mediated lysis at the single effector cell level. I. Kinetic analysis of lethal hits and target cell lysis in multicellular conjugates. Journal of Immunology 123(4) pp. 1604-9. [Web of Science] [Pubmed]
1978
Cerottini J. C., Chapuis B., Mach J. P., Louis J., 12-1978. Aspects immunologiques du cancer bronchique. [Immunological aspects of bronchial carcinoma (author's transl)]. Therapeutische Umschau 35(12) pp. 988-92. [Web of Science] [Pubmed]
Heiniger H. J., Brunner K. T., Cerottini J. C., 11-1978. Cholesterol is a critical cellular component for T-lymphocyte cytotoxicity. Proceedings of the National Academy of Sciences of the United States of America 75(11) pp. 5683-7. [DOI] [Web of Science] [Pubmed]
Linna T. J., Engers H. D., Cerottini J. C., Brunner K. T., 05-1978. Inhibition of cytolytic T lymphocyte activity with subcellular alloantigen preparations and with unlabeled allogeneic target cells. Journal of Immunology 120(5) pp. 1544-9. [Web of Science] [Pubmed]
1977
Cerottini J. C., 12-1977. Concepts recents de l'immunite a mediation cellulaire. [Recent concepts in cell mediated immunity]. Schweizerische Medizinische Wochenschrift 107(48) pp. 1717-21. [Web of Science] [Pubmed]
Cerottini J. C., 11-1977. Lymphoid cells as effectors of immunologic cytolysis. Hospital Practice 12(11) pp. 57-68. [Web of Science] [Pubmed]
1976
Cerottini J. C., Engers H. D., Fitch F. W., Brunner K. T., 09-1976. Generation of cytolytic t lymphocytes in vitro from alloimmune spleen cells. Transplantation Proceedings 8(3) pp. 387-91. [Web of Science] [Pubmed]
Fitch F. W., Engers H. D., Cerottini J. C., Bruner K. T., 03-1976. Generation of cytotoxic T lymphocytes in vitro. VII. Suppressive effect of irradiated MLC cells on CTL response. Journal of Immunology 116(3) pp. 716-23. [Web of Science] [Pubmed]
Harris J. W., MacDonald H. R., Engers H. D., Fitch F. W., Cerottini J., 04-1976. Increased cytolytic T lymphocyte activity induced by 2-mercaptoethanol in mixed leukocyte cultures: kinetics and possible mechanisms of action. Journal of Immunology 116(4) pp. 1071-7. [Web of Science] [Pubmed]
Thomas K., Engers H. D., Cerottini J. C., Brunner K. T., 04-1976. Enzymatic removal of H-2 alloantigens from the surface of P815-(X2) mouse tumor cells. European Journal of Immunology 6(4) pp. 257-62. [DOI] [Web of Science] [Pubmed]
1975
Engers H. D., MacDonald H. R., Cerottini J. C., Brunner K. T., 03-1975. Effect of delayed addition of 2-mercaptoethanol on the generation of mouse cytotoxic T lymphocytes in mixed leukocyte cultures. European Journal of Immunology 5(3) pp. 223-5. [DOI] [Web of Science] [Pubmed]
Engers H. D., Thomas K., Cerottini J. C., Brunner K. T., 08-1975. Generation of cytotoxic T lymphocytes in vitro. V. Response of normal and immune spleen cells to subcellular alloantigens. Journal of Immunology 115(2) pp. 356-60. [Web of Science] [Pubmed]
Fitch F. W., Engers H. D., MacDonald H. R., Cerottini J. C., Brunner K. T., 12-1975. Generation of cytotoxic T lymphocytes in vitro. VI. Effect of cell density on response in mixed leukocyte cultures. Journal of Immunology 115(6) pp. 1688-94. [Web of Science] [Pubmed]
MacDonald H. R., Sordat B., Cerottini J. C., Brunner K. T., 09-1975. Generation of cytotoxic T lymphocytes in vitro. IV. Functional activation of memory cells in the absence of DNA synthesis. Journal of Experimental Medicine 142(3) pp. 622-36. [DOI] [Web of Science] [Pubmed]
Plata F., Cerottini J. C., Brunner K. T., 04-1975. Primary and secondary in vitro generation of cytolytic T lymphocytes in the murine sarcoma virus system. European Journal of Immunology 5(4) pp. 227-33. [DOI] [Web of Science] [Pubmed]
1974
Cerottini J. C., Brunner K. T., 1974. Cell-mediated cytotoxicity, allograft rejection, and tumor immunity. Advances in Immunology 18 pp. 67-132. [Pubmed]
Cerottini J. C., Engers H. D., Macdonald H. R., Brunner T., 09-1974. Generation of cytotoxic T lymphocytes in vitro. I. Response of normal and immune mouse spleen cells in mixed leukocyte cultures. Journal of Experimental Medicine 140(3) pp. 703-17. [DOI] [Web of Science] [Pubmed]
Cerottini J. C., Mach J. P., 09-1974. Cancer et immunite [Cancer and immunity]. Revue Médicale de la Suisse Romande 94(9) pp. 675-84. [Pubmed]
Macdonald H. R., Engers H. D., Cerottini J. C., Brunner K. T., 09-1974. Generation of cytotoxic T lymphocytes in vitro. II. Effect of repeated exposure to alloantigens on the cytotoxic activity of long-term mixed leukocyte cultures. Journal of Experimental Medicine 140(3) pp. 718-30. [DOI] [Web of Science] [Pubmed]
Mach J. P., Carrel S., Merenda C., Sordat B., Cerottini J. C., 04-1974. In vivo localisation of radiolabelled antibodies to carcinoembryonic antigen in human colon carcinoma grafted into nude mice. Nature 248(450) pp. 704-6. [DOI] [Web of Science] [Pubmed]
1973
Cerottini J. C., MacDonald H. R., Brunner K. T., 12-1973. Formation of cytotoxic lymphocytes in mixed leukocyte culture systems: introduction. Transplantation Proceedings 5(4) pp. 1621-4. [Web of Science] [Pubmed]
Cerottini J. C., Mach J. P., Isliker H., 12-1973. L'utilite des tests immunologiques en cancerologie. [Use of immunologic tests in cancerology]. Helvetica Chirurgica Acta 40(5) pp. 551-9. [Web of Science] [Pubmed]
Shortman K., Byrd W. J., Cerottini J. C., Brunner K. T., 01-1973. Characterisation and separation of mouse lymphocyte subpopulations responding to phytohemagglutinin and pokeweed mitogens. Cellular Immunology 6(1) pp. 25-40. [DOI] [Web of Science] [Pubmed]
Vasudevan D. M., Brunner K. T., Cerottini J. C., 08-1973. Increased cytolytic effect of immune lymphocytes in a syngeneic tumour system following simple purification procedures. British Journal of Cancer. Supplement 1 pp. 35-6. [Web of Science] [Pubmed]
1972
Cerottini J. C., 08-1972. Aspects cellulaires de l'induction de la reponse immunitaire. [Cellular aspects of the induction of the immune response]. Schweizerische Medizinische Wochenschrift 102(33) pp. 1138-41. [Web of Science] [Pubmed]
Cerottini J. C., Brunner K. T., 04-1972. Lymphocytes cytotoxiques et immunite antitumorale. [Cytotoxic lymphocytes and anti-tumor immunity]. Annales de l Institut Pasteur 122(4) pp. 659-68. [Web of Science] [Pubmed]
Cerottini J. C., Brunner K. T., 06-1972. Reversible inhibition of lymphocyte-mediated cytotoxicity by cytochalasin B. Nat New Biol 237(78) pp. 272-3. [Web of Science] [Pubmed]
Cerottini J. C., Freedman L. R., Brunner K. T., 09-1972. In vivo activity of cytotoxic lymphocytes. Transplantation Proceedings 4(3) pp. 299-301. [Web of Science] [Pubmed]
Freedman L. R., Cerottini J. C., Brunner K. T., 12-1972. In vivo studies of the role of cytotoxic T cells in tumor allograft immunity. Journal of Immunology 109(6) pp. 1371-8. [Web of Science] [Pubmed]
Grey H. M., Kubo R. T., Cerottini J. C., 11-1972. Thymus-derived (T) cell immunoglobulins. Presence of a receptor site for IgG and absence of large amounts of "buried" Ig determinants on T cells. Journal of Experimental Medicine 136(5) pp. 1323-8. [DOI] [Web of Science] [Pubmed]
Shortman K., Brunner K. T., Cerottini J. C., 06-1972. Separation of stages in the development of the "T" cells involved in cell-mediated immunity. Journal of Experimental Medicine 135(6) pp. 1375-91. [DOI] [Web of Science] [Pubmed]
Shortman K., Byrd W., Williams N., Brunner K. T., Cerottini J. C., 06-1972. The separation of different cell classes from lymphoid organs. The relationship between the adherence properties and the buoyant density of sub-populations of "B" and "T" lymphocytes. Australian Journal of Experimental Biology and Medical Science 50(3) pp. 323-36. [Web of Science] [Pubmed]
Shortman K., Cerottini J. C., Brunner K. T., 08-1972. The separation of sub-populations of T and B lymphocytes. European Journal of Immunology 2(4) pp. 313-9. [DOI] [Web of Science] [Pubmed]
1971
Cerottini J. C., 02-1971. Structure et activite biologique des anticorps. [Structure and biological activity of antibodies]. Schweizerische Medizinische Wochenschrift 101(6) pp. 177-81. [Web of Science] [Pubmed]
Cerottini J. C., Unanue E. R., 03-1971. Genetic control of the immune response of mice to hemocyanin. I. Th role of macrophages. Journal of Immunology 106(3) pp. 732-9. [Web of Science] [Pubmed]
Nordin A. A., Cerottini J. C., Brunner K. T., 01-1971. The antibody response of mice to allografts as determined by a plaque assay with allogeneic target cells. European Journal of Immunology 1(1) pp. 55-6. [Pubmed]
Pelet J., Brunner K. T., Nordin A. A., Cerottini J. C., 08-1971. The relative distribution of cytotoxic lymphocytes and of alloantibody-forming cells in albumin density gradients. European Journal of Immunology 1(4) pp. 238-42. [Pubmed]
1970
Cerottini J. C., Nordin A. A., Brunner K. T., 07-1970. In vitro cytotoxic activity of thymus cells sensitized to alloantigens. Nature 227(5253) pp. 72-3. [DOI] [Web of Science] [Pubmed]
Cerottini J. C., Nordin A. A., Brunner K. T., 12-1970. Specific in vitro cytotoxicity of thymus-derived lymphocytes sensitized to alloantigens. Nature 228(5278) pp. 1308-9. [DOI] [Web of Science] [Pubmed]
Cerottini J. C., Trnka Z., 1970. The role of persisting antigen in the development of immunological memory. International Archives of Allergy and Applied Immunology 38(1) pp. 37-41. [DOI] [Web of Science] [Pubmed]
Unanue E. R., Cerottini J. C., 04-1970. The function of macrophages in the immune response. Seminars in Hematology 7(2) pp. 225-48. [Web of Science] [Pubmed]
Unanue E. R., Cerottini J. C., 04-1970. The immunogenicity of antigen bound to the plasma membrane of macrophages. Journal of Experimental Medicine 131(4) pp. 711-25. [DOI] [Web of Science] [Pubmed]
1969
Cerottini J. C., Grey H. M., 12-1969. Binding properties of monoclonal gammaG-antiglobulin factors with human gamma G. Annals of the New York Academy of Sciences 168(1) pp. 76-83. [DOI] [Web of Science] [Pubmed]
Cerottini J. C., Lambert P. H., Dixon F. J., 11-1969. Comparison of the immune responsiveness of NZB and NZB X NZW F1 hybrid mice with that of other strains of mice. Journal of Experimental Medicine 130(5) pp. 1093-105. [DOI] [Web of Science] [Pubmed]
Cerottini J. C., McConahey P. J., Dixon F. J., 08-1969. Specificity of the immunosuppression caused by passive administration of antibody. Journal of Immunology 103(2) pp. 268-75. [Web of Science] [Pubmed]
Cerottini J. C., McConahey P. J., Dixon F. J., 04-1969. The immunosuppressive effect of passively administered antibody IgG fragments. Journal of Immunology 102(4) pp. 1008-15. [Web of Science] [Pubmed]
Unanue E. R., Cerottini J. C., Bedford M., 06-1969. Persistence of antigen on the surface of macrophages. Nature 222(5199) pp. 1193-5. [DOI] [Web of Science] [Pubmed]
1968
Cerottini J. C., 09-1968. An antigen-binding capacity test for human immunoglobulin G (IgG) fragments. Journal of Immunology 101(3) pp. 433-8. [Web of Science] [Pubmed]
Cerottini J. C., Fitch F., 1968. Complement-fixing ability and antibody activity of rabbit F(ab')2 antibody. International Archives of Allergy and Applied Immunology 34(2) pp. 188-200. [DOI] [Web of Science] [Pubmed]
McConahey P. J., Cerottini J. C., Dixon F. J., 05-1968. An approach to the quantitation of immunogenic antigen. Journal of Experimental Medicine 127(5) pp. 1003-11. [DOI] [Web of Science] [Pubmed]
1967
Cerottini J. C., Brunner K. T., 10-1967. Localization of mouse isoantigens on the cell surface as revealed by immunofluorescence. Immunology 13(4) pp. 395-403. [Web of Science] [Pubmed]
Cerottini J. C., Webb T., 1967. Preparation and use of specifically purified antibodies for immunofluorescent labeling. Acta Histochemica 27(2) pp. 225-34. [Web of Science] [Pubmed]
Levinthal J. D., Cerottini J. C., Ahmad-Zadeh C., Wicker R., 03-1967. The detection of intracellular adenovirus type 12 antigens by indirect immunoferritin technique. International Journal of Cancer 2(2) pp. 85-102. [DOI] [Web of Science] [Pubmed]
Levinthal J. D., Wicker R., Cerottini J. C., 03-1967. Study of intracellular SV40 antigens by indirect immunoferritin technique. Virology 31(3) pp. 555-8. [DOI] [Web of Science] [Pubmed]
1966
1964
Cerottini J. C., Jaton J., Froidevaux T., Isliker H., 1964. Immunofluorescence 'a l'aide de fragments d'anticorps. [Immunofluorescence by Means of Antibody Fragments.]. Helvetica Physiologica et Pharmacologica Acta 22 pp. C9-12. [Web of Science] [Pubmed]

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