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Anne Ruef

Doctoral Student
Lemanic Neurosciences Program 
University of Lausanne (UNIL)


email: anne.ruef@gmail.com


Laboratoire de recherche en Neuroimagerie - LREN
Departement des neurosciences cliniques
Centre Hospitalier Universitaire Vaudois (CHUV)
Mont Paisible 16
1011 Lausanne



Research interests

My research topic is to understand the mechanisms underlying brain structure changes in Mood disorders and their relationship to the clinical phenotype. I’m interested to find markers that define and predict the evolution of Uni- and Bipolar disorders. For this, I use the last developments of quantitative and diffusion magnetic resonance imaging to investigate brain tissue properties – myelin, iron and water - and link brain structure to clinical and cognitive dimension using mass multivariate linear models.



Maillard AM, Ruef A*, Pizzagalli F, Migliavacca E, Hippolyte L, Adaszewski S, Dukart J, Ferrari C, Conus P, Männik K, Zazhytska M, Siffredi V, Maeder P, Kutalik Z, Kherif F, Hadjikhani N; Beckmann JS, Reymond A, Draganski B, Jacquemont S; 16p11 2 European Consortium (2014). The 16p11.2 locus modulates brain structures common to autism, schizophrenia and obesity. Molecular Psychiatry. (* Shared first authorship).

Ruef A, Curtis L, Moy G, Bessero S, Ba M B, Lazeyras F, Lovblad K-O, Haller S, Malafosse A, Giannakopoulos P and Merlo M. (2012). Magnetic resonance imaging correlates of first-episode psychosis in young adult male patients: combined analysis of grey and white matter. Journal of Psychiatry & Neuroscience : JPN, 37(5), 305–312. doi:10.1503/jpn.110057



Lorio S, Kherif F, Ruef A, Melie-Garcia L, Frackowiak R, Ashburner J, Helms G, Lutti A, Draganski B (2016). Neurobiological origin of spurious brain morphological changes: A quantitative MRI study. Hum Brain Mapp.

Lorio S, Lutti A, Kherif F, Ruef A, Dukart J, Chowdhury R, Frackowiak RS, Ashburner J, Helms G, Weiskopf N, Draganski B (2014). Disentangling in vivo the effects of iron content and atrophy on the ageing human brain. Neuroimage.



CHUV - Rue du Bugnon 46 - CH-1011 Lausanne  -  Tel. +41 21 314 95 93  -  Fax +41 21 314 12 56
Swiss University