Publications from our lab (established 2001)


E. Dorcey, A. Rodriguez-Villalon, P. Salinas, L. Santuari, S. Pradervand, K. Harshman and C.S. Hardtke (2012): Context-dependent dual role of SKI8 homologs in mRNA synthesis and turnover. PLoS Genetics, Vol. 8: e1002652.

D. Pacheco-Villalobos and C.S. Hardtke (2012): Natural genetic variation of root system architecture from Arabidopsis to Brachypodium: towards adaptive value. Philosophical Transactions of the Royal Society B, Vol. 367: pp. 1552-1558.


L. Santuari, E. Scacchi, A. Rodriguez-Villalon, P. Salinas, E.M.N. Dohmann, G. Brunoud, T. Vernoux, R.S. Smith and C.S. Hardtke (2011): Positional information by differential endocytosis splits auxin response to drive Arabidopsis root meristem growth. Current Biology, Vol. 21: pp. 1918-1923.

L. Ragni, K. Nieminen, D. Pacheco-Villalobos, R. Sibout, C. Schwechheimer and C. S. Hardtke
(2011): A direct stimulatory role of mobile gibberellin in Arabidopsis hypocotyl xylem expansion. The Plant Cell, Vol. 23: pp. 1322-1336.

M. Sankar, K. S. Osmont, J. Rolcik, B. Gujas, D. Tarkowska, M. Strnad, I. Xenarios and C. S. Hardtke
(2011): A qualitative continuous model of cellular auxin and brassinosteroid signaling and their crosstalk. Bioinformatics, Vol. 27, pp. 1404-1412.

S. Depuydt and C. S. Hardtke
(2011): Hormone Signalling Crosstalk in Plant Growth Regulation. Current Biology, Vol. 21: pp. R365-R373.

C. S. Hardtke and K. Nieminen
(2011): Advances in identifying and exploiting natural genetic variation. Plant biotechnology and agriculture: Prospects for the 21st century, pp. 195-205.


E. Scacchi, P. Salinas, B. Gujas, L. Santuari, N. Krogan, L. Ragni, T. Berleth and C. S. Hardtke (2010): Spatio-temporal sequence of cross-regulatory events in root meristem growth. Proceedings of the National Academy of Sciences U.S.A., Vol. 107: pp. 22734-22739.

L. Santuari and C. S. Hardtke (2010): The case for resequencing studies of Arabidopsis thaliana accessions: mining the dark matter of natural genetic variation. Faculty of 1000 Reports, Vol 2: pp. 85.

J. Beuchat, E. Scacchi, D. Tarkowska, L. Ragni, M. Strnad and C. S. Hardtke (2010): BRX promotes Arabidopsis shoot growth. New Phytologist, Vol. 188: pp. 23-29.

J. Beuchat, S. Li, L. Ragni, C. Shindo, M. H. Kohn and C. S. Hardtke
(2010): A hyperactive QTL allele of Arabidopsis BRX contributes to natural variation in root growth vigor. Proceedings of the National Academy of Sciences U.S.A., Vol. 107: pp. 8475-8480.

L. Santuari , S. Pradervand , A. M. Amiguet-Vercher , J. Thomas , E. Dorcey , K. Harshman , I. Xenarios , T. E. Juenger and C. S. Hardtke (2010): Substantial deletion overlap among divergent Arabidopsis genomes revealed by intersection of short reads and tiling arrays. Genome Biology, Vol. 11: pp. R4


S. Haye and C. S. Hardtke (2009): The Roundtable on Sustainable Biofuels: plant scientist input needed. Trends in Plant Science, Vol. 14: pp. 409-412.

E. Scacchi, K. S. Osmont, J. Beuchat, P. Salinas, M. Navarrete-Gómez, M. Trigueros, C. Ferrándiz and C. S. Hardtke (2009): Dynamic, auxin-responsive plasma membrane to nucleus movement of Arabidopsis BRX. Development, Vol. 136: pp. 2059-2067.

S. Plantegenet, J. Weber, D. R. Goldstein, G. Zeller, C. Nussbaumer, J. Thomas, D. Weigel, K. Harshman and C. S. Hardtke (2009): Comprehensive analysis of Arabidopsis expression level polymorphisms with simple inheritance. Molecular Systems Biology, 5, 242.

A. Rodrigues, J. Santiago, S. Rubio, A. Saez, K. S. Osmont, J. Gadea, C. S. Hardtke and P. L. Rodriguez (2009): The short-rooted phenotype of the brevis radix mutant partly reflects root ABA hypersensitivity. Plant Physiology, Vol. 149: pp. 1917-28.


C. Shindo, G. Bernasconi and C. S. Hardtke (2008): Intra-specific competition reveals conditional fitness effects of single gene polymorphism at the Arabidopsis root growth regulator BRX. New Phytologist, Vol. 180: pp. 71-80.

K. S. Osmont and C. S. Hardtke (2008): The topless plant developmental phenotype explained! Genome Biology, Vol. 9: pp. 219-222.

R. Sibout, S. Plantegenet and C. S. Hardtke (2008): Flowering as a condition for xylem expansion in Arabidopsis hypocotyl & root. Current Biology, Vol. 18: pp. 458-463.

C. S. Hardtke and K. U. Torii (2008): Plant growth and development - the new wave. Current Opinions in Plant Biology, Vol. 11: pp. 1-3.


C. S. Hardtke, E. Dorcey, K. S. Osmont and R. Sibout (2007): Phytohormone collaboration: zooming in on auxin-brassinosteroid interactions. Trends in Cell Biology, Vol. 17: pp. 485-492.

C. S. Hardtke (2007): Transcriptional auxin-brassinosteroid crosstalk: who's talking? BioEssays, Vol. 29: pp. 1115-1123.

K. S. Osmont, R. Sibout and C. S. Hardtke (2007): Hidden Branches: Developments in Root System Architecture. Annual Review of Plant Biology, Vol. 58: pp. 93-113.

C. Shindo, G. Bernasconi and C. S. Hardtke (2007): Natural genetic variation in Arabidopsis: tools, traits and prospects for Evolutionary Ecology. Annals of Botany, Vol. 99: pp. 1043-1054.


R. Sibout, P. Sukuma, C. Hettiarachchi, M. Holm, G. K. Muday and C. S. Hardtke (2006): Opposite root growth phenotypes of hy5 vs. hy5 hyh mutants correlate with increased constitutive auxin signaling. PLoS Genetics, Vol. 2: pp. 1898-1911, e202. Open Access link

C. F. Mouchel, K. S. Osmont and C. S. Hardtke (2006): BRX mediates feedback between brassinosteroid levels and auxin signalling in root growth. Nature, Vol. 443: pp. 458-461. PubMed link

G. C. Briggs, K. S. Osmont, C. Shindo, R. Sibout and C. S. Hardtke (2006): Unequal genetic redundancies in Arabidopsis - a neglected phenomenon? Trends in Plant Sciences, Vol. 11: pp. 492-498. PubMed link

G. C. Briggs, C. F. Mouchel and C. S. Hardtke (2006): Characterization of the plant-specific BRX gene family reveals limited genetic redundancy despite high sequence conservation. Plant Physiology, Vol. 140: pp. 1306-1316. PubMed link

C. S. Hardtke (2006): Root development: Branching into novel spheres. Current Opinions in Plant Biology, Vol. 9: pp. 66-71. PubMed link


C. F. Mouchel, G. C. Briggs and C. S. Hardtke (2004): Natural genetic variation in Arabidopsis identifies BREVIS RADIX, a novel regulator of cell proliferation and elongation in the root. Genes & Development, Vol. 18: pp. 700-714. PubMed link

C. P. Cluis, C. F. Mouchel and C. S. Hardtke (2004): The Arabidopsis transcription factor HY5 integrates light and hormone signaling pathways. The Plant Journal, Vol. 38: pp. 332-347. PubMed link

C. S. Hardtke, W. Ckurshumova, D. P. Vidaurre, S. A. Singh, G. Stamatiou, S. B. Tiwari, G. Hagen, T. J. Guilfoyle and T. Berleth (2004): Overlapping and non-redundant functions of the Arabidopsis Auxin Response Factors MONOPTEROS and NONPHOTOTROPIC HYPOCOTYL 4. Development, Vol. 131: pp. 1089-1100. PubMed link


C. S. Hardtke (2003): Gibberellin Signaling: GRASs Growing Roots. Current Biology, Vol. 13: pp. R366-R367. PubMed link


P. Kosarev, K. F. X. Mayer and C. S. Hardtke (2002): Evaluation and classification of RING finger domains encoded by the Arabidopsis genome. Genome Biology, Vol. 3: pp. 16.1-16.12. Open Access link

C. S. Hardtke, H. Okamoto, C. Stoop-Myer and X.-W. Deng (2002): Biochemical evidence for ubiquitin ligase activity of the COP1 interacting protein CIP8. The Plant Journal, Vol. 30: pp. 385-394. PubMed link