Jessica Delhaye

My research interest is the ecology and evolution of host-parasite interactions. Just like competition and predation, parasitism has a huge impact on a variety of species. Parasite species develop different mechanisms which confer on them the ability to live, grow and reproduce in their hosts, and which make them more or less virulent to these hosts. This induces the emergence of numerous defense adaptations in infected species (intermediate and definitive hosts) and implicates trade-offs between parasite defence and other life history traits like self-maintenance (food intake, ageing) and reproduction (sexual trait development, health signaling, breeding success).
Oxidative stress appears when an oxidative imbalance occurs. Pro-oxidants are natural byproducts of metabolism. These components are released by mitochondrial transport chain, during the mitochondrial respiration and ATP production, and by immune cells involved in immune response. When they are not sufficiently counteracted by antioxidant defenses, pro-oxidants induce cellular damage to lipids, proteins and DNA.
Research have shown that pro-oxidant production, antioxidant availability and amount of oxidative damage could be linked to a lot of other parameters like self-maintenance, ageing, fight against parasites, secondary sexual trait development, breeding success, etc…
My PhD project is about the host-parasite interaction between great tits (Parus major) and the malaria parasite (Plasmodium sp.) and its vector mosquitoes (Culex pipiens). One major aspect of the project is the effect of host-parasite interaction on host oxidative stress.



Biophore - CH-1015 Lausanne
Tel. +41 21 692 41 60
Fax +41 21 692 41 65