Microbial Pathogenesis


 

Microbial pathogenesis

Staphylococcus aureus causes a wide spectrum of infections in humans. Virulence in S. aureus is mediated by cell wall-associated and secreted proteins. Cell wall-associated proteins enable the bacteria to adhere to tissue components. Our studies have focused on the contribution to virulence of bacterial surface adhesins, such as the fibrinogen-binding protein, or clumping factor A (ClfA), and the fibronectin-binding protein A (FnbA), using a gene transfer approach. Our current work addressed how these proteins interact in the initiation and further development of the infection process.

Contact:

Philippe Moreillon
Prof. honoraire

DMF
Quartier UNIL-Sorge
Bâtiment Biophore 2415.2
CH - 1015 Lausanne
Phone: 021 692 56 09
email : 
Philippe.Moreillon -at/unil.ch 

Biophore - CH-1015 Lausanne
Switzerland
Tel. +41 21 692 56 00
Fax +41 21 692 56 05