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Liens UNIL
Host laboratories in Bioinformatics
CIG - Center for Integrative Genomics
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Structure, function and evolution of chemosensory systems. |
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Our research aims at understanding, through genomic approaches, how the interplay between various transcription factors and the corresponding regulatory networks, controls metabolic homeostasis in physiological and pathological conditions. The liver and white adipose tissue (WAT), which are important organs with respect to energy balance, are the main targets of our studies. |
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Reseach in the Franken lab focusses on the genetics and energetics of sleep homeostasis and circadian rhythms in the mouse using a variety of –omics (transcriptome, metabolome, epigenome, microRNAs), behavioral (activity, qEEG), imaging (life imaging of gene expression), and modelling techniques. |
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Our group explores the molecular mechanisms and physiological functions of biological timekeeping by circadian clocks in mammals. |
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Influence of genome structure on phenotypes. |
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I am interested in understanding how ecosystems of microbes evolve over time, and how they are shaped by the interactions taking place between individual microbial cells. |
DEE - Department of Ecology and Evolution
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We try to understand how the interplay of population structure, trait architecture, and selection affect evolutionnary processes. For this, we use different approaches, from theory and the development of statistical tools to data mining and field observations. Jérôme Goudet lab |
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We link genome evolution with evolution of development, using bioinformatics. © Images from Wikimedia Commons |
DCB - Department of Computational Biology
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We are interested in applying computational methods and evolutionary modeling to test hypotheses about the evolution and adaptation of species using both genmic, phenotypic and ecological data. |
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We develop and apply methods for the integrative analysis of large-scale biological and clinical data, as well as small regulatory systems. |
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We work on molecular genetics and genomics of hereditary retinal degeneration, an area of research that is a paradigm for both medical genetics and neurodegenerative conditions. |
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Our research by combines the predictive power of computational biology with extensive genetic and molecular analysis of candidates and aims to understand what are the contributions to homeostasis, phenotypic variation and disease of long noncoding RNAs (lincRNAs). |
DMF - Department of Fundamental Microbiology
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We study microbial symbiosis with a focus on gut microbiota-host interactions. Our current work is centered on honey bees and related social bee species. |
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Our group is interested in understanding how ecosystems of microbes evolve over time, and how they are shaped by the interactions taking place between individual microbial cells, strains and species. |
IMUL - Institute of Microbiology
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Our lab aims at better understanding HIV life cycle and its interactions with the human cell, in order to identify novel strategies to eradicate HIV as well as to develop new tools for gene therapy and lab applications. |
IUMSP - Institute of Social and Preventive Medicine
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Development of statistical methods for the better understanding of the genetic architecture of complex traits. |
LICR@UNIL - Ludwig Center for Cancer Research of the UNIL
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We are developing new computational approaches to study the relationship between immune and cancer cells in tumors and how this could help optimizing immunotherapy treatments. |
SIB - Swiss Institute of Bioinformatics
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In the Bioinformatics Core Facility BCF of UniL-SIB we entertain a broad range of collaborations and of bioinformatics activities with a focus on statistical-epidemiological methodology for OMICS data and on applications in medicine and oncology (explorative analyses, prognostic and predictive biomarkers, personalized medicine). |
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Computer-aided protein engineering and drug design for cancer therapy. |
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Consulting for the life and medical research on bioinformatics and computational biology, from infrastructure to analysis methods. |
