Directeur de la plateforme
Bruno M. Humbel graduated in Biochemistry at the Federal Institute of Technology (ETH), Zurich, Switzerland. He was privileged to do his Ph.D., Dr. sc. nat. ETH, research at the Institute of Cell Biology, ETH Zurich, with Dr. Martin Müller, known for his seminal contributions in cryo-preparations and cryo-SEM. My thesis director was Prof. Dr. Hans Moor, the inventor of freeze-etching and high-pressure freezing. After a postdoc period of four years with Prof. Dr. Günter Gerisch at the Max-Planck-Institute for Biochemistry in Munich, I joined the lab for Electron Microscopy and Structure Analysis, Molecular Cell Biology, at Utrecht University in the group of Prof. Dr. Arie J. Verkleij, where I held the position of an associate professor. Since 2010 I am director of the Electron Microscopy Facility at the University of Lausanne.
My main interest is to develop preparation methods for (electron) microscopy, which not only allow a glimpse into life at high resolution, but also enable identification and localisation of the machinery of life within cells. The aim is to visualise the living cell at low resolution and to zoom in to analyse its ultrastructure at high resolution: The gateway to in situ biological nanostructures. Currently, my research focuses on correlative light and electron microscopy and to introduce the FIB-SEM technology, volume microscopy, into life science.
At EMF I support our scientific community in evaluating their projects to find the best suited method to answer the scientific question and to discuss the obtained results. The new developments in technology are meant for the benefit of UNIL and other academic institutions. I am teaching electron microscopy and preparation methods at UNIL and at international workshops.