Publications

Links | 2019 | 2017 | 2016 | 2015 | Selected Publications
 

Links

Unisciences: www.unil.ch/unisciences/lilianetenenbaum

ORCID (Open Researcher and Contributor ID):ID 0000-0003-4619-9660

 

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2019

Lasbleiz C , Mestre-Frances N, Devau G, Luquin R, Tenenbaum L, Kremer EJ , Verdier J-M. (2019). Combining gene transfer and nonhuman primates to better understand and treat Parkinson’s disease. Front. Mol. Neurosci. doi: 10.3389/fnmol.2019.00010.

 

Dwir, D., Giangreco, B., Xin, L., Tenenbaum, L., Cabungcal, J.-H., Steullet, P., Goupil, A. , Cleusix, M., Jenni, R., Baumann, P. , Klauser, P. , Conus, P., Tirouvanziam, R.,  Cuenod, M,  KDo. .Q. (2019). MMP9 / RAGE pathway overactivation mediates redox dysregulation and neuroinflammation, leading to inhibitory / excitatory imbalance: a reverse translation study in schizophrenia patients. Mol. Psychiat.  doi: 10.1038/s41380-019-0393-5.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

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2017

Tenenbaum L. and Humbert-Claude M. (2017). Glial cell line-Derived Neurotrophic Factor gene delivery in Parkinson’s disease: a delicate balance between neuroprotection, trophic effects and unwanted compensatory mechanisms. Front. Neuroanat. doi: 10.3389/fnana.2017.00029

Liu, S., Sandner, B., Schackel, T., Nicholson, L., Chtarto, A., Tenenbaum, L., Puttagunta, R., Müller, R., Weidner, R., Blesch, A. (2017). Regulated Viral BDNF Delivery in Combination with Schwann Cells Promotes Axonal Regeneration through Capillary Alginate Hydrogels after Spinal Cord Injury. Acta Biomater. 2017;60:167-180

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2016

Barroso-Chinea P., Cruz-Muros I., Afonso-Oramas D., Castro-Hernández J., Salas-Hernández J., Chtarto A., Luis-Ravelo D., Humbert-Claude M., Tenenbaum L. and González-Hernández T. (2016).
Long-term controlled GDNF over-expression reduces dopamine transporter activity without affecting tyrosine hydroxylase expression in the rat mesostriatal system. Neurobiol. Dis. 88 : 44–54.

Chtarto A,  Humbert-Claude M and Bockstael O, Das AT, Boutry S, Breger L, Barroso-Chinea P, Klaver B, Melas C, González-Hernández T, Müller R, DeWitte O, Levivier M, Lundberg C, Berkhout B, and Tenenbaum L . (2016) A regulatable AAV vector mediating GDNF biological effects at clinically-approved sub-antimicrobial doxycycline doses.  Mol. Ther. Methods and Clin. Dev.. 5, 16027; doi:10.1038.

Das A.T., Tenenbaum L., and Berkhout B. (2016). Tet-On systems for doxycycline-inducible gene expression. Curr Gene Ther. 16:156-67.

Bazewicz,M., Draganova,D., Makhoula, M, Chtarto,A., Elmaleh,V, Tenenbaum,L., Caspers,L., Bruyns,C., Willermain,F. (2016). Effect of SOCS1 overexpression on RPE cell activation by proinflammatory cytokines. Neuroscience Letters 630:209–215.

Humbert-Claude M, Duc D, Dwir D, Thieren L, Sandström von Tobel J, Begka C, Legueux F, Velin D, Maillard MH, Do KQ, Monnet-Tschudi F, Tenenbaum L. (2016). Tollip, an early regulator of the acute inflammatory response in the substantia nigra. J Neuroinflammation: 13(1):303.

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2015

Hanna-El-Daher, L., Béard, E., Henry, H., Tenenbaum, L. and Braissant, O. (2015). Mild elevation of guanidinoacetate under partial GAMT deficiency strongly affects brain cell development. Neurobiol. Dis. 79 :14-27

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Selected Publications

Tenenbaum L. , J.L.Darling and E.Hooghe-Peters (1994). Adeno-associated virus (AAV) as a vector for gene transfer into glial cells of the central nervous system. Gene Ther, vol.1, suppl.1,80.

Tenenbaum L., F.Jurysta, A.Stathopoulos, Z.Puschban, C.Melas, W.T.J.M.C. Hermens, J.Verhaagen, B.Pichon, T.Velu and M.Levivier. (2000). Tropism of AAV-2 vectors for neurons of the globus pallidus. NeuroReport, 11,2277-2283.

Tenenbaum L., A. Chtarto, E. Lehtonen, D. Blum , V. Baekelandt, T.Velu, J.Brotchi and M. Levivier (2002). Neuroprotective Gene Therapy for Parkinson’s disease. Curr. Gene Ther. 2, 451-483.

Chtarto A., H.U.Bender, C.O.Hanemann, T.Kemp, E.Lehtonen, M. Levivier , J. Brotchi, T.Velu and L. Tenenbaum (2003. Tetracycline-inducible transgene expression mediated by a single AAV vector. Gene Ther. 10, 86-96.

L.Tenenbaum, E.Lehtonen and P.Monahan. (2003). Evaluation of risks related to the use of adeno-associated virus-based vectors. Curr. Gene Ther. 3: 545-565.

Tenenbaum L., A. Chtarto, E. Lehtonen, T.Velu, J.Brotchi and M. Levivier (2004). Recombinant AAV-mediated gene delivery to the Central Nervous System. J. Gene Med. 6 Suppl 1:S212-22.

Tenenbaum L., M. Peschanski, C.Melas F.Rodesh, E.Lehtonen, A.Stathopoulos, A.Chtarto, T. Velu, J.Brotchi and M. Levivier (2004). Efficient early and sustained transduction of human fetal mesencephalon using AAV2 vectors. Cell Transplant 13, 565-571.

 

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