Auditory Sensation & Perception

Object Recognition | Perceptual Decision-Making & Cognitive Control | Spatial Processing & Learning-induced Plasticity
 

Object Recognition

Principal  Investigators

  • Prof. Micah M. Murray
  • Prof. Stephanie Clarke (Neuropsychology and Neurorehabilitation Service, CHUV-UNIL)

Overview

This line of research, carried out in close collaboration with the group of Prof. Stephanie Clarke (Neuropsychology and Neurorehabilitation Service, CHUV-UNIL), identifies the spatio-temporal brain dynamics by whcih sounds are recognized as objects. This includes, but is not limited to, categorical discrimination, priming/learning, vocalization discrimination, action-related associations, as well as the interplay between sound identity and sound localization on object processing.

Representative Publications

  • Bourquin NM, Murray MM, Clarke S (2013) Position-independent and position-linked representations of sound objects. Neuroimage, 73: 40-49.
  • Bourquin NM, Spierer L, Murray MM, Clarke S. (2012) Neural plasticity associated with recently versus often heard objects. Neuroimage 62: 1800-1806.
  • De Lucia M, Tzovara A, Bernasconi F, Spierer L, Murray MM. (2012) Auditory perceptual decision-making based on semantic categorization of environmental sounds. Neuroimage, 60: 1704-15.
  • De Lucia M, Clarke S, Murray MM. (2010). A temporal hierarchy for conspecific vocalization discrimination in humans. Journal of Neuroscience, 30:11210-11221.
  • De Lucia M, Cocchi L, Martuzzi R, Meuli R, Clarke S, Murray MM. (2010) Perceptual and semantic contributions to repetition priming of environmental sounds. Cerebral Cortex, 20: 1676-1684.
  • De Lucia M, Camen C, Clarke S, Murray MM. (2009) The role of actions in auditory object discrimination. Neuroimage, 48: 476-486.
  • Aeschlimann M, Knebel JF, Murray MM, Clarke S. (2008) Emotional pre-eminence of human vocalizations. Brain Topography 20: 239-248.
  • Murray MM, Camen C, Spierer L, Clarke S (2008) Plastic representations of environmental sounds revealed by electrical neuroimaging. Neuroimage 39: 847-856.
  • Murray MM, Camen C, Andino SLG, Bovet P, Clarke S (2006) Rapid brain discrimination of sounds of objects. Journal of Neuroscience 26: 1293-1302.

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Perceptual Decision-Making & Cognitive Control

Principal Investigators

Overview

The neural mechanisms that allow conscious access to incoming sensory stimuli has been mainly investigated in the visual and somatosensory modalities. In the auditory domain, this research has been based almost exclusively on linguistic materials. This project identifies the neural mechanisms that link the sensory evidence to the perceptual decision using various types of auditory stimuli. In particular I seek to understand how auditory stimuli are represented as a function of subjects' conscious access, experimental task and context, and how these representations relate to the perceptual decision.

Representative Publications

  • De Lucia M, Tzovara A, Bernasconi F, Spierer L, Murray MM. (2012) Auditory perceptual decision-making based on semantic categorization of environmental sounds. Neuroimage 60: 1704-15.
  • Manual A, Bernasconi F, Murray MM, Spierer L. (2012) Spatio-temporal brain dynamics mediating post-error behavioral adjustments. Journal of Cognitive Neuroscience, 24: 1331-1343.
  • Bernasconi F, De Lucia M, Tzovara A, Manual A, Murray MM, Spierer L. (2011). Noise in brain activity engenders perception and influences discrimination sensitivity. Journal of Neuroscience, 31:17971–17981.
  • Manuel A, Grivel J, Bernasconi F, Murray MM, Spierer L. (2010) Brain dynamics underlying training-induced improvement in suppressing inappropriate action. Journal of Neuroscience, 30:13670-8.

 

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Spatial Processing & Learning-induced Plasticity

Principal Investigators

Overview

This line of research investigates how the spatial position of sounds is encoded and how these representations can be made plastic via training/learning. This is of particular relevance in clinical populations in whom spatial representations are impaired and disrupt not only spatial analysis of auditory scenes, but also functions linked to object recognition. This work is carried in close collaboration with Prof. Stephanie Clarke (Neuropsychology and Neurorehabilitation Service, CHUV-UNIL) and Dr. Lucas Spierer (Neurology Department, University of Fribourg).

Representative Publications

  • Spierer L, De Lucia M, Bernasconi F, Grivel J, Bourquin N, Clarke S, Murray MM (2011). Learning-induced plasticity in human audition: objects, space, and time. Hearing Research 271, 88-102.
  • Spierer L, Bellmann-Thiran A, Maeder P, Murray MM, Clarke S. (2009) Hemispheric competence for auditory spatial representation. Brain 132: 1953–1966.
  • Murray MM, Spierer L. (2009) Auditory spatio-temporal brain dynamics and their consequences for multisensory interactions in humans. Hearing Research, 258: 118-130.
  • Spierer L, Bourquin N, Tardif E, Murray MM, Clarke S. (2009) Right hemispheric dominance for echo suppression. Neuropsychologia 47: 465-472.
  • Spierer L, Murray MM, Tardif E, Clarke S. (2008) The path to success in auditory spatial discrimination: Electrical neuroimaging responses within the supratemporal plane predict performance outcome. Neuroimage 41:493-503.
  • Tardif E, Spierer L, Clarke S, Murray MM. (2008) Interactions between auditory ‘what’ and ‘where’ pathways enhance sub-threshold discrimination of frequency and position. Neuropsychologia, 46: 952-960.
  • Spierer L, Tardif E, Sperdin H, Murray MM, Clarke S (2007) Learning-induced plasticity in auditory spatial representations revealed by electrical neuroimaging. Journal of Neuroscience 27: 5474-5483.
  • De Santis L, Clarke S, Murray MM (2007) Automatic and intrinsic auditory ‘what’ and ‘where’ processing in humans revealed by electrical neuroimaging. Cerebral Cortex 17: 9-17.
  • Tardif E, Murray MM, Meylan R, Spierer L, Clarke S (2006) The spatio-temporal brain dynamics of processing and integrating sound localization cues in humans. Brain Res 1092: 161-176.
  • Ducommun CY, Murray MM, Thut G, Bellmann A, Viaud-Delmon I, Clarke S, Michel CM (2002) Segregated processing of auditory motion and auditory location: an ERP mapping study. Neuroimage 16: 76-88.

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