Department of Physiology (CHUV-UNIL)
Department of Neurology (University of Fribourg)
German Institute of Human Nutrition Potsdam-Rehbrücke
Nestle Research Center
This interdisciplinary project combines the expertise of two research groups to better understand links between brain activity, hormone secretion, and eating behaviour. On the one hand, the Service of Endocrinology, Diabetes and Metabolism (SEDM) has established methods for the monitoring of gastric hormones linked to glucose homeostasis (Rodieux et al., 2008). On other hand, the EEG Brain Mapping Core of the Center for Biomedical Imaging (EEG-CIBM) has used electrical neuroimaging methods to identify how the brain tracks the energetic value of food images (Toepel et al., 2009). Also, the project aims at determining the parallels between Roux-en-Y gastric bypass (RYGB) - and its associated effects on gastric hormone levels and eating behaviour - and brain activity during visual food discrimination. For this purpose, hormone blood measures are correlated with neural responses as measured by electroencephalography (EEG) in healthy normal-weighted and obese controls without surgery, as well as in RYGB patients before and after food intake.