About the Laboratories of Neuroinflammation

Multiple sclerosis (MS) is an auto-inflammatory disease of the central nervous system, where all components of the immune system, innate and adaptive, are involved.In addition to genetic factors, environmental ones play a crucial role in triggering this complex disease.

In the Laboratories of neuroimmunology, we examine how environmental factors, among which Epstein-Barr virus, gut microbiome or cholesterol metabolites favor autoreactivity of B and T cells. To tackle our hypothesis, we use different approaches including animal models, namely the experimental autoimmune encephalomyelitis, human samples analysis (blood, cerebrospinal fluid, urine, stools) of MS patients and a human in vitro model of MS brain, using induced pluripotent stem cells (iPCS).

Chemin des Boveresses 155 - C02-202 - CH-1015 Lausanne
Tel. +41 21 314 25 62
Centre Hospitalier Universitaire Vaudois (CHUV)Université de Lausanne