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Martinon Fabio, Associate Professor


 

Biography

Fabio Martinon received his PhD in 2003 from the University of Lausanne for his work on the characterization of the Inflammasome in the laboratory of Jürg Tschopp. After a short post-doctoral fellowship in Jürg Tschopp’s laboratory, he moved in 2006 to the laboratory of Laurie Glimcher at the Harvard School of Public Health, where he investigated the link between inflammatory programs and the endoplasmic reticulum stress response. In August 2010 he joined the Department of Biochemistry as Assistant Professor. His current research focuses on the characterization of signaling pathways emerging from the endoplasmic reticulum.

Research interests

Cellular stress is a hallmark of severe pathogenic insults that leads to the activation of adaptation programs aimed at restoring tissue homeostasis. This state of reversible malfunction is defined by the notion of stress. Tissue stress and malfunction promotes low-grade inflammation that helps the tissue to cope with damage and restore tissue function. This low-grade inflammation also termed para-inflammation illustrates how stress and possibly stress response pathways can regulate immunity. A variety of diseases are characterized by inflammation and cellular homeostasis deregulation including viral infections, cancer and autoinflammatory syndromes. However, the mechanisms and the role of these stress responses and their impact on the inflammatory pathways are poorly understood. We developed a research program aimed at identifying stress-signaling pathways that regulate inflammation. Our research is aimed at characterizing the stress-inflammation connection in autoinflammatory diseases and cancer.
 

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Publications

 
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Person Position Contact
Bojan Bujisic Postdoctoral fellow Unisciences
Sérgio De Freitas Ribeiro Postdoctoral fellow Unisciences
Mélanie Op PhD student Unisciences
Katerina Theodoropoulou Visiting Scientist
Léa Zaffalon Technician Unisciences

Alumni

Aude de Gassart Postdoctoral fellow
Jérôme Lugrin Postdoctoral fellow
Benoît Allaz Trainee
Yvan Jamilloux Visiting Ph.D student
Antonia Di Micco Ph.D student
Gianluca Frera Ph.D student
Rémy Tallant Ph.D student
Emma Proïcs Erasmus student
Rébecca Panes Premaster student 2013
Marianne Ethenoz Technician
Einar Castillo Technician
Evgeniia Prokhorova SUR Programme 2016 Lomonosov Moscow State University
Zaiyue Shu Student SUR Programme 2013 Shanghai Jiao Tong University
Patricia Renck Nunes Premaster student 2012 UNIL
Nicoletta Corti Premaster student 2012 UNIL
Malak Benslimane Student SUR Programme 2012 Univ. of Wisconsin at Madison
Basiglio Giangreco Premaster student 2011 UNIL

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Contact

Martinon_web2.jpg

Fabio Martinon

fabio.martinon@unil.ch

Tel: + 41 21 692 5695

Chemin des Boveresses 155 - CH-1066 Epalinges  - Switzerland  -  Tel. +41 21 692 5700  -  Fax +41 21 692 5705
Swiss University