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Publications | Masters and Phd thesis

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The human CD8 T stem cell-like memory phenotype appears in the acute phase in Yellow Fever virus vaccination

Marraco Silvia A. Fuertes, Bovay Amandine, Nassiri Sina, Maby-El Hajjami Hélène, Ouertatani-Sakouhi Hajer, Held Werner, Speiser Daniel E..

[DOI][serval:BIB_D644B7DF7CE4]

NFAT5 induction by the tumor microenvironment enforces CD8 T cell exhaustion

Tillé Laure, Cropp Daniela, Bodley Gabrielle, Andreatta Massimo, Charmoy Mélanie, Crespo Isaac, Nassiri Sina, Lourenco Joao, Leblond Marine, Lopez-Rodriguez Cristina et al..

[DOI][serval:BIB_3D15B154D604]

In Press

Elucidating the neurological mechanism of the FLASH effect in juvenile mice exposed to hypofractionated radiotherapy.

Allen B.D., Alaghband Y., Kramár E.A., Ru N., Petit B., Grilj V., Petronek M.S., Pulliam C.F., Kim R.Y., Doan N.L. et al. Neuro-oncology. Peer-reviewed.

[DOI][Pmid][serval:BIB_59C4BBA5ABCD]

preview resource BIB_0C98FBD02368.P001

Patients' experiences with cancer care in Switzerland: Results of a multicentre cross-sectional survey.

Arditi C., Eicher M., Colomer-Lahiguera S., Bienvenu C., Anchisi S., Betticher D., Dietrich P.Y., Duchosal M., Peters S., Peytremann-Bridevaux I. European journal of cancer care pp. e13705. Peer-reviewed.

[URN][DOI][WoS][Pmid][serval:BIB_0C98FBD02368]

International assessment of interobserver reproducibility of flap delineation in head and neck carcinoma.

Beddok A., Guzene L., Coutte A., Thomson D., Yom S., Calugaru V., Blais E., Gilliot O., Racadot S., Pointreau Y. et al. Acta oncologica pp. 1-8. Peer-reviewed.

[DOI][Pmid][serval:BIB_ECADD78C324F]

Ré-irradiation de compression médullaire sur foyer d’hématopoïèse extra médullaire : présentation d’un cas [Re-irradiation of bone marrow compression on a focus of extra medullary hematopoiesis: Presentation of a case]

Bernard G., Bennassi A., Dereme J., Ozsahin M., Kinj R. Cancer radiotherapie. Peer-reviewed.

[DOI][Pmid][serval:BIB_5743992797E8]

The minimal FLASH sparing effect needed to compensate the increase of radiobiological damage due to hypofractionation for late-reacting tissues.

Böhlen T.T., Germond J.F., Bourhis J., Bailat C., Bochud F., Moeckli R. Medical physics. Peer-reviewed.

[DOI][Pmid][serval:BIB_A5B6F25E2105]

A phase 1, open-label study of pasireotide in patients with BRAF- and NRAS wild type, unresectable, and/or metastatic melanoma

Dummer R., Michielin O.A., Nägeli M., Goldinger S.M., Campigotto F., Kriemler-Krahn U., Schmid H., Pedroncelli A., Micaletto S., Schadendorf D. ESMO Open.

[serval:BIB_9AB4FCA2FF27]

EML4-ALK Variant Impacts ALK Resistance Mutations

Früh M, Peters S JCO.

[serval:BIB_FF5B731030A6]

Antibody response and intra-host viral evolution after plasma therapy in COVID-19 patients pre-exposed or not to B-cell-depleting agents.

Gachoud D., Pillonel T., Tsilimidos G., Battolla D., Dumas D., Opota O., Fontana S., Vollenweider P., Manuel O., Greub G. et al. British journal of haematology. Peer-reviewed.

[DOI][WoS][Pmid][serval:BIB_801AF06A907A]

Treatment Characteristics and Real-World Progression-Free Survival in Patients with Unresectable Stage III NSCLC who Received Durvalumab After Chemoradiotherapy: Findings from the PACIFIC-R Study.

Girard N., Bar J., Garrido P., Garassino M.C., McDonald F., Mornex F., Filippi A.R., Smit HJM, Peters S., Field J.K. et al. Journal of thoracic oncology. Peer-reviewed.

[DOI][Pmid][serval:BIB_D36FA0602240]

Design and validation of a dosimetric comparison scheme tailored for ultra-high dose-rate electron beams to support multicenter FLASH preclinical studies.

Gonçalves Jorge P., Melemenidis S., Grilj V., Buchillier T., Manjappa R., Viswanathan V., Gondré M., Vozenin M.C., Germond J.F., Bochud F. et al. Radiotherapy and oncology. Peer-reviewed.

[DOI][Pmid][serval:BIB_FC59EAAA1608]

Molecular markers of response to anti-PD1 therapy in advanced hepatocellular carcinoma.

Haber P.K., Castet F., Torres-Martin M., Andreu-Oller C., Puigvehí M., Maeda M., Radu P., Dufour J.F., Verslype C., Czauderna C. et al. Gastroenterology. Peer-reviewed.

[DOI][Pmid][serval:BIB_5E664B01B65D]

Eribulin as first-line treatment in older patients with advanced breast cancer: A multicenter phase II trial [SAKK 25/14].

Hasler-Strub U., Mueller A., Li Q., Thuerlimann B., Ribi K., Gerber S., von Moos R., Fehr M., Rochlitz C., Zaman K. et al. Journal of geriatric oncology. Peer-reviewed.

[DOI][Pmid][serval:BIB_1D987C9B9D86]

European Association of Neuro-Oncology (EANO) Guidelines for Treatment of Primary Central Nervous System lymphoma (PCNSL).

Hoang-Xuan K., Deckert M., Ferreri AJM, Furtner J., Gallego Perez-Larraya J., Henriksson R., Hottinger A.F., Kasenda B., Lefranc F., Lossos A. et al. Neuro-oncology. Peer-reviewed.

[DOI][Pmid][serval:BIB_E39A5D50A7EF]

Comparing radiolytic production of H<sub>2</sub>O<sub>2</sub> and development of Zebrafish embryos after ultra high dose rate exposure with electron and transmission proton beams.

Kacem H., Psoroulas S., Boivin G., Folkerts M., Grilj V., Lomax T., Martinotti A., Meer D., Ollivier J., Petit B. et al. Radiotherapy and oncology. Peer-reviewed.

[DOI][Pmid][serval:BIB_9CD75B81043D]

Immunobiology of high-grade serous ovarian cancer: lessons for clinical translation.

Kandalaft L.E., Dangaj Laniti D., Coukos G. Nature reviews. Cancer. Peer-reviewed.

[DOI][WoS][Pmid][serval:BIB_7B0D5013539C]

Study protocol for the OligoMetastatic Esophagogastric Cancer (OMEC) project: A multidisciplinary European consensus project on the definition and treatment for oligometastatic esophagogastric cancer.

Kroese T.E., van Rossum PSN, Nilsson M., Lordick F., Smyth E.C., Rosati R., Nafteux P., D'Ugo D., Chaudry M.A., Polkowkski W. et al. European journal of surgical oncology. Peer-reviewed.

[DOI][Pmid][serval:BIB_F9C8EA647E0C]

Lung stereotactic radiation therapy: Intercomparison of irradiation devices in terms of outcome and predictive factors.

Le Reun E., Casutt A., Durham A., Bouchaab H., Romano E., Lovis A., Krueger T., Von Garnier C., Özsahin E.M., Kinj R. Cancer radiotherapie. Peer-reviewed.

[DOI][Pmid][serval:BIB_0833BFD8386F]

Pembrolizumab versus placebo as adjuvant therapy for completely resected stage IB-IIIA non-small-cell lung cancer (PEARLS/KEYNOTE-091): an interim analysis of a randomised, triple-blind, phase 3 trial.

O'Brien M., Paz-Ares L., Marreaud S., Dafni U., Oselin K., Havel L., Esteban E., Isla D., Martinez-Marti A., Faehling M. et al. The Lancet. Oncology. Peer-reviewed.

[DOI][Pmid][serval:BIB_AB45342CF3A7]

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Masters thesis

Publications (12)

Neurological adverse events associated with cancer immunotherapies: literature review and database development

DESBAILLETS N., 2020. 36, Université de Lausanne, Faculté de biologie et médecine, HOTTINGER A. (dir.).

[serval:BIB_3DC9613DC448]

Cancer immunotherapy toxicities: A case report and review of the literature

PILLONEL V., 2020. 30, Université de Lausanne, Faculté de biologie et médecine, PETERS S. (dir.).

[serval:BIB_F87BF4F6DC09]

Traitement néoadjuvant par folfirinox pour le cancer du pancréas borderline résécable et localement avancé

GIROD F., 2019. 29, Université de Lausanne, Faculté de biologie et médecine, HALKIC N. (dir.).

[serval:BIB_5D1D59591501]

Effects of baseline medication on immune-related adverse events occurring during combination immunotherapy: an exploratory study

HOSTETTLER M., 2019. 27, Université de Lausanne, Faculté de biologie et médecine, MICHIELIN O. (dir.).

[serval:BIB_481488956F55]

preview resource BIB_CF31BAE8EA59.P001

Etude rétrospective des effets secondaires des immunothérapies oncologiques sur les systèmes endocriniens

SAAS A., 2018. 25, Université de Lausanne, Faculté de biologie et médecine, SYKIOTIS G. (dir.).

[URN][serval:BIB_CF31BAE8EA59]

preview resource BIB_447A8DAAFFEA.P001

Bien-être spirituel et qualité de vie chez les patients atteints d'un cancer pulmonaire avancé : une étude exploratoire

TARASI B., 2018. 29, Université de Lausanne, Faculté de biologie et médecine, MAZZOCATO C. (dir.).

[URN][serval:BIB_447A8DAAFFEA]

preview resource BIB_05D8A7499C74.P001

Protocole de traitement du glioblastome

RAEMY A., 2017. 34, Université de Lausanne, Faculté de biologie et médecine, HOTTINGER A. (dir.).

[URN][serval:BIB_05D8A7499C74]

preview resource BIB_3EE2DE923528.P001

Intérêt du PET/CT au 68Ga-NODAGA-RGD pour l’évaluation de la néoangiogenèse tumorale, dans le cadre des lymphomes non hodgkinien avec extension extra-ganglionnaire

TUNEZ K., 2017. 22, Université de Lausanne, Faculté de biologie et médecine, PRIOR J. (dir.).

[URN][serval:BIB_3EE2DE923528]

preview resource BIB_AD0E970E95CE.P001

CANCER IMMUNOTHERAPY WITH VEGFR-3 TARGETED CAR T-CELLS

KIRITSIS K., 2016. 32, Université de Lausanne, Faculté de biologie et médecine, COUKOS G. (dir.).

[URN][serval:BIB_AD0E970E95CE]

preview resource BIB_6CA64A104A0D.P001

Identification of immune cells in melanoma with single-cell RNA-sequencing

WICKY A., 2016. 28, Université de Lausanne, Faculté de biologie et médecine, GFELLER D. (dir.).

[URN][serval:BIB_6CA64A104A0D]

preview resource BIB_A9FD8716E3C9.P001

Optimisation d'une approche pour l'analyse de l'expression de gènes au niveau unicellulaire chez des sous-populations spécialisées de lymphocytes T CD4+ humaines

DENEREAZ L., 2014. 30, Université de Lausanne, Faculté de biologie et médecine, ROMERO P. (dir.).

[URN][serval:BIB_A9FD8716E3C9]

preview resource BIB_1098EE681B9C.P001

Le mélanome et les polymorphismes associés au dysfonctionnement du système immunitaire

Naso S., 2012. 25, Université de Lausanne, Faculté de biologie et médecine, Romero P (dir.).

[URN][serval:BIB_1098EE681B9C]

Phd thesis

In preparation (2)

PD-1 preserves the stem-like properties of memory-like CD8+ T cells during chronic viral infection

Maier Julia Malaika, Université de Lausanne, Faculté de biologie et médecine, Held Werner (dir.).

[URN][serval:BIB_BA6CDD6096C9]

preview resource BIB_AFACC70D6A3C.P002

Developmental origin of central memory CD8+ T cells

Pais Ferreira Daniela, Université de Lausanne, Faculté de biologie et médecine, Held Werner (dir.).

[URN][serval:BIB_AFACC70D6A3C]

Publications (35)

Mapping the fate of CD8+ T cells during acute and chronic viral infection

Gomes da Silva Joana, 2022/03/04., Université de Lausanne, Faculté de biologie et médecine, HELD Werner (dir.).

[URN][serval:BIB_134EA7DCB378]

Dual antigen targeted chimeric antigen receptor T cell therapy for multiple myeloma

CAMVIEL Nicolas, 2022., Université de Lausanne, Faculté de biologie et médecine, Arber Caroline (dir.).

[serval:BIB_85F245E0AE55]

Développement de thérapies par lymphocytes T à récepteur chimérique antigénique pour le traitement de la leucémie myéloïde aigue

LANZ Inès, 2022., Université de Lausanne, Faculté de biologie et médecine, Arber Caroline (dir.).

[serval:BIB_24D69F70B29B]

PD-l preserves the stem-like properties of memorylike CD8+ T cells during chronic viral infection

MAIER Julia Malaika, 2022., Université de Lausanne, Faculté de biologie et médecine, Held Werner (dir.).

[URN][serval:BIB_8F0F5A35E056]

preview resource BIB_5EF9D31ADF10.P002

Characterization of the interaction between circulating human Innate Lymphoid Cell Progenitors and endothelial cells

Vanoni Giulia, 2021/02/10., Université de Lausanne, Faculté de biologie et médecine, Romero Pedro (dir.).

[URN][serval:BIB_5EF9D31ADF10]

Characterization of the responsiveness of patient- derived melanoma cells to T cell-derived cytokines

MARTIGNIER Christophe, 2021., Université de Lausanne, Faculté de biologie et médecine, Speiser Daniel E. (dir.).

[URN][serval:BIB_6F2AC667E988]

preview resource BIB_9B9FC01687DF.P001

Slowness Predicts Mortality: A Comparative Analysis of Walking Speed And Moberg Picking-Up Tests

MEYER May-Lucie, 2021., Université de Lausanne, Faculté de biologie et médecine, Santos-Eggimann Brigitte (dir.).

[URN][serval:BIB_9B9FC01687DF]

preview resource BIB_22651FF6D862.P002

Novel antibody-based therapeutic approaches for redirecting T cell effector functions towards tumors expressing CD248 (TEM1)

Fierle Julie Katrin, 2020/04/06., Université de Lausanne, Faculté de biologie et médecine, Coukos George (dir.).

[URN][serval:BIB_22651FF6D862]

preview resource BIB_7417869DA8E8.P002

Development of novel methods for high-throughput analyses of human tumor antigen-specific CD4 T cell responses

Rockinger Georg Alexander, 2020/02/28., Université de Lausanne, Faculté de biologie et médecine, Romero Pedro (dir.).

[URN][serval:BIB_7417869DA8E8]

Rendering adoptively transferred T cells resistant to cyclic adenosine monophosphate-mediated suppression

Alatzoglou Dimitrios, 2020., Université de Lausanne, Faculté de biologie et médecine, Coukos George (dir.).

[serval:BIB_3C12BAADB14B]

NeoTIL: Enriched TIL cultures for tumor antigen discovery and next-generation cellular immunotherapy

Arnaud Marion, 2020., Université de Lausanne, Faculté de biologie et médecine, Harari Alexandre (dir.).

[serval:BIB_5836F8B4B8EE]

preview resource BIB_E74407D0442F.P002

Implementation of the Symptom Navi Program for cancer patients in ambulatory services: A cluster randomised pilot study (Symptom Navi Pilot Study)

BANA Marika, 2020., Université de Lausanne, Faculté de biologie et médecine, Eicher Manuela (dir.).

[URN][serval:BIB_E74407D0442F]

Immunoreactivity of ovarian cancer and responses to targeted therapy and immunotherapy

Bruand Marine, 2020., Université de Lausanne, Faculté de biologie et médecine, Coukos George (dir.).

[serval:BIB_77A2A01AA965]

preview resource BIB_E6A1E69D2351.P001

An Integrated Immunopeptidomics and Proteogenomics Framework to Discover Non-Canonical Targets for Cancer Immunotherapy

CHONG Chloe, 2020., Université de Lausanne, Faculté de biologie et médecine, Coukos George (dir.).

[URN][serval:BIB_E6A1E69D2351]

Novel Combinatorial Gene-Engineered T-cell Transfer Strategy that Reprograms the Tumor Immune Landscape for Enhanced Tumor Control and Survival

Corria Osorio Angel de Jesus, 2020., Université de Lausanne, Faculté de biologie et médecine, Coukos George (dir.).

[serval:BIB_40F8F4BC12AB]

Enforced PGC-1ɑ expression promotes CD8 T cell fitness, memory formation and anti-tumor immunity

DUMAUTHIOZ Nina, 2020., Université de Lausanne, Faculté de biologie et médecine, Romero Pedro (dir.).

[serval:BIB_2D4ABE6915B2]

Identification of structural determinants of Iight chain amyloidosis

Garofalo Maura, 2020., Université de Lausanne, Faculté de biologie et médecine, Michielin Olivier (dir.).

[serval:BIB_3C9116AAC4B7]

preview resource BIB_5172A4EA1817.P001

Deciphering the Landscape of HLA class-I and class-II Phosphopeptidomes leads to Robust Predictions of Phosphorylated HLA ligands

SOLLEDER Marthe, 2020., Université de Lausanne, Faculté de biologie et médecine, Gfeller David (dir.).

[URN][serval:BIB_5172A4EA1817]

preview resource BIB_C4EC0725191A.P001

D-AREdevil: a novel approach for discovering disease-associated rare cell populations in mass cytometry data

SUFFIOTTI Madeleine, 2020., Université de Lausanne, Faculté de biologie et médecine, Pantaleo Giuseppe (dir.).

[URN][serval:BIB_C4EC0725191A]

CD36-mediated metabolic adaptation supports regulatory T cell survival and function in tumors

Wang Haiping, 2020., Université de Lausanne, Faculté de biologie et médecine, Ho Ping-Chih (dir.).

[serval:BIB_CD6DDB37D481]

Control of perivascular cell differentiation by endothelial cells

Wetterwald Laureline, 2020., Université de Lausanne, Faculté de biologie et médecine, Petrova Tatiana (dir.).

[serval:BIB_B26A56531CD1]

preview resource BIB_5EBE536D2CB3.P003

Molecular and functional immune determinants associated with the optimal immunogenicity of Yellow Fever vaccination in humans

Bovay Amandine Xuan Kim, 2019/06/07., Université de Lausanne, Faculté de biologie et médecine, Speiser Daniel (dir.).

[URN][serval:BIB_5EBE536D2CB3]

Study and modulation of the immune microenvironment in a pre-clinical lung cancer model to optimize radiation-therapy efficiency.

Boivin Gael, Vozenin Marie-Catherine, 2019., Université de Lausanne, Faculté de biologie et médecine, Bourhis Jean (dir.).

[serval:BIB_AB942FA3E259]

Cytolytic CD4 T cells: Analysis of a novel T cell candidate for human tumor immunotherapy

Cachot Amélie, 2019., Université de Lausanne, Faculté de biologie et médecine, Romero Pedro (dir.).

[serval:BIB_F0A6BE95CE46]

Molecular mechanisms regulating TCR affinity-improved T cells against the NY-ESO-1 tumor antigen

ERDES Efe, 2019., Université de Lausanne, Faculté de biologie et médecine, Rufer Nathalie (dir.).

[serval:BIB_6F539C8E9170]

preview resource BIB_E25A9568380B.P001

Identification and Isolation of Highly Functional Tumor-Specific CD8 T Cenis for Adoptive Cell Transfer Therapy

MAGNIN Morgane, 2019., Université de Lausanne, Faculté de biologie et médecine, HARARI Alexandre (dir.).

[URN][serval:BIB_E25A9568380B]

Molecular mechanisms of lymphatic vascular maintenance and repair

Saygili-Demir Cansaran, 2019., Université de Lausanne, Faculté de biologie et médecine, Petrova Tatiana (dir.).

[serval:BIB_A491C5859416]

preview resource BIB_1C9878253833.P002

Normal Brain, Neural Stem Cells and Glioblastoma Responses to FLASH Irradiation

Montay-Gruel Pierre, 2018/08/24. 258, Université de Lausanne, Faculté de biologie et médecine, Vozenin Marie-Catherine (dir.).

[URN][serval:BIB_1C9878253833]

preview resource BIB_08CEE3B79D75.P003

Molecular determinants governing CD8+ T cell mediated anti-tumor immunity

Martinez-Usatorre Amaia, 2018/04/27. 117, Université de Lausanne, Faculté de biologie et médecine, Romero Pedro (dir.).

[URN][serval:BIB_08CEE3B79D75]

preview resource BIB_786BC3B46C6D.P002

Harnessing iNKT and CD8 T cells for Immunotherapy of Cancer

Tschumi Benjamin Olivier, 2018/03/13. 117, Université de Lausanne, Faculté de biologie et médecine, Romero Pedro (dir.).

[URN][serval:BIB_786BC3B46C6D]

preview resource BIB_9F9512EEBA1F.P001

Characterization of local and systemic immune-modulation in melanoma patients

Bordy N., 2015. 204, Université de Lausanne, Faculté de biologie et médecine, Speiser D., Swartz M. (dir.).

[URN][serval:BIB_9F9512EEBA1F]

preview resource BIB_D0E8499331FE.P001

The reasons for discrepancies in target volume delineation: a SASRO study on head-and-neck and prostate cancer

Jeanneret Sozzi W., 2006. 8, Université de Lausanne, Faculté de biologie et médecine, Mirimanoff R.-O. (dir.).

[URN][serval:BIB_D0E8499331FE]

preview resource BIB_31C9E8336D36.P001

Pronostic factors in solitary plasmacytoma of the bone: A Rare Cancer Network study

Knobel D., 2006. 9, Université de Lausanne, Faculté de biologie et médecine, Ozsahin E.M. (dir.).

[URN][serval:BIB_31C9E8336D36]

preview resource BIB_2B983A4B5188.P001

Primary spinal epidural lymphoma: patients' profile, outcome, and prognostic factors: a multicenter Rare Cancer Network study

Monnard V., 2006. 7, Université de Lausanne, Faculté de biologie et médecine, Mirimanoff R.-O. (dir.).

[URN][serval:BIB_2B983A4B5188]

Radiothérapie trifractionnée accélérée seule ou alternée avec la chimiothérapie chez des patients souffrant d'un cancer localement évolué de la sphère ORL : analyse de la toxicité tardive

Laszlo André, 2001. 7, Université de Lausanne, Faculté de médecine, Mirimanoff René-Olivier (dir.).

[URN][serval:BIB_03C435C3DD4B]

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