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Department of Oncology

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Publications | Masters and Phd thesis

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Publications

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In Press | 2020 | ...

The human CD8 T stem cell-like memory phenotype appears in the acute phase in Yellow Fever virus vaccination

Marraco Silvia A. Fuertes, Bovay Amandine, Nassiri Sina, Maby-El Hajjami Hélène, Ouertatani-Sakouhi Hajer, Held Werner, Speiser Daniel E..

[DOI][serval:BIB_D644B7DF7CE4]

In Press

STACAS: Sub-Type Anchor Correction for Alignment in Seurat to integrate single-cell RNA-seq data.

Andreatta M., Carmona S.J. Bioinformatics. Peer-reviewed.

[DOI][Pmid][serval:BIB_D3F01C447F08]

Early drop of circulating T cells negatively correlates with the protective immune response to Yellow Fever vaccination.

Bovay A., Speiser D.E., Fuertes Marraco S.A. Human vaccines & immunotherapeutics pp. 1-8. Peer-reviewed.

[DOI][Pmid][serval:BIB_CF63CEAB6BA5]

High-throughput automated organoid culture via stem-cell aggregation in microcavity arrays.

Brandenberg N., Hoehnel S., Kuttler F., Homicsko K., Ceroni C., Ringel T., Gjorevski N., Schwank G., Coukos G., Turcatti G. et al. Nature biomedical engineering. Peer-reviewed.

[DOI][WoS][Pmid][serval:BIB_71E34713FAA0]

Lactate modulation of immune responses in inflammatory versus tumour microenvironments.

Certo M., Tsai C.H., Pucino V., Ho P.C., Mauro C. Nature reviews. Immunology. Peer-reviewed.

[DOI][Pmid][serval:BIB_EEC32C274BAF]

Efficacy of chemotherapy and atezolizumab in patients with non-small-cell lung cancer receiving antibiotics and proton pump inhibitors: pooled post hoc analyses of the OAK and POPLAR trials.

Chalabi M., Cardona A., Nagarkar D.R., Dhawahir Scala A., Gandara D.R., Rittmeyer A., Albert M.L., Powles T., Kok M., Herrera F.G. et al. Annals of oncology. Peer-reviewed.

[DOI][Pmid][serval:BIB_BC73060F5887]

Structural dissimilarity from self drives neoepitope escape from immune tolerance.

Devlin J.R., Alonso J.A., Ayres C.M., Keller GLJ, Bobisse S., Vander Kooi C.W., Coukos G., Gfeller D., Harari A., Baker B.M. Nature chemical biology. Peer-reviewed.

[DOI][WoS][Pmid][serval:BIB_186F0AD1C570]

Enforced PGC-1α expression promotes CD8 T cell fitness, memory formation and antitumor immunity.

Dumauthioz N., Tschumi B., Wenes M., Marti B., Wang H., Franco F., Li W., Lopez-Mejia I.C., Fajas L., Ho P.C. et al. Cellular & molecular immunology. Peer-reviewed.

[DOI][Pmid][serval:BIB_D554C59D6F3C]

Metabolic and epigenetic regulation of T-cell exhaustion.

Franco F., Jaccard A., Romero P., Yu Y.R., Ho P.C. Nature metabolism. Peer-reviewed.

[DOI][Pmid][serval:BIB_C6CC159592FD]

Durable response to palbociclib and letrozole in ovarian cancer with CDKN2A loss.

Frisone D., Charrier M., Clement S., Christinat Y., Thouvenin L., Homicsko K., Michielin O., Bodmer A., Chappuis P.O., McKee T.A. et al. Cancer biology & therapy pp. 1-6. Peer-reviewed.

[DOI][WoS][Pmid][serval:BIB_DDF548EFECDC]

Editorial overview: Pharmaceutical biotechnology: new frontiers in cancer immunotherapy.

Kandalaft L.E., Graciotti M. Current opinion in biotechnology. Peer-reviewed.

[DOI][Pmid][serval:BIB_6F4B29364362]

Intratumoural immunotherapies for unresectable and metastatic melanoma: current status and future perspectives.

Middleton M.R., Hoeller C., Michielin O., Robert C., Caramella C., Öhrling K., Hauschild A. British journal of cancer. Peer-reviewed.

[DOI][WoS][Pmid][serval:BIB_ED664BCFFB6F]

A multicentre randomised phase III trial comparing pembrolizumab vs single-agent chemotherapy for advanced pre-treated malignant pleural mesothelioma: the European Thoracic Oncology Platform (ETOP 9-15) PROMISE-meso trial.

Popat S., Curioni-Fontecedro A., Dafni U., Shah R., O'Brien M., Pope A., Fisher P., Spicer J., Roy A., Gilligan D. et al. Annals of oncology. Peer-reviewed.

[URN][DOI][Pmid][serval:BIB_0FC8052F2621]

Optimized low-dose combinatorial drug treatment boosts selectivity and efficacy of colorectal carcinoma treatment.

Zoetemelk M., Ramzy G.M., Rausch M., Koessler T., van Beijnum J.R., Weiss A., Mieville V., Piersma S.R., de Haas R.R., Delucinge-Vivier C. et al. Molecular oncology. Peer-reviewed.

[DOI][WoS][Pmid][serval:BIB_6B1C1DF10DF7]

2020

Integrated proteogenomic deep sequencing and analytics accurately identify non-canonical peptides in tumor immunopeptidomes

Chong Chloe, Müller Markus, Pak HuiSong, Harnett Dermot, Huber Florian, Grun Delphine, Leleu Marion, Auger Aymeric, Arnaud Marion, Stevenson Brian J. et al., 2020/12. Nature Communications, 11 (1). Peer-reviewed.

[DOI][Pmid][serval:BIB_03EA897A1141]

CIITA-transduced glioblastoma cells uncover a rich repertoire of clinically relevant tumor-associated HLA-II antigens

Greta Forlani, Justine Michaux, HuiSong Pak, Florian Huber, Elodie Lauret Marie Joseph, Elise Ramia, Brian J Stevenson, Michael Linnebacher, Roberto Accolla, Michal Bassani-Sternberg, 2020/09/22. Molecular & Cellular Proteomics. Peer-reviewed.

[DOI][serval:BIB_848F6AADEDBE]

What Role Can Process Mining Play in Recurrent Clinical Guidelines Issues? A Position Paper.

Gatta R., Vallati M., Fernandez-Llatas C., Martinez-Millana A., Orini S., Sacchi L., Lenkowicz J., Marcos M., Munoz-Gama J., Cuendet M.A. et al., 2020/09/11. International journal of environmental research and public health, 17 (18) pp. E6616. Peer-reviewed.

[DOI][Pmid][serval:BIB_F0FD74FBD2EB]

Survival of the fetus: cervical cancer and pregnancy, a challenging combination.

Levy L., Meuwly J.Y., Sarivalasis A., Achtari C., Mathevet P., Herrera F.G., 2020/09/05. Lancet, 396 (10252) p. 725. Peer-reviewed.

[DOI][Pmid][serval:BIB_16AC5A00A805]

T-cell repertoire analysis and metrics of diversity and clonality.

Chiffelle J., Genolet R., Perez M.A., Coukos G., Zoete V., Harari A., 2020/09/01. Current opinion in biotechnology, 65 pp. 284-295. Peer-reviewed.

[DOI][Pmid][serval:BIB_598F3EDCA20B]

High versus low dose irradiation for tumor immune reprogramming.

de Olza M.O., Bourhis J., Irving M., Coukos G., Herrera F.G., 2020/09/01. Current opinion in biotechnology, 65 pp. 268-283. Peer-reviewed.

[DOI][Pmid][serval:BIB_330632946BBD]

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Masters thesis

Publications (2)

Effects of baseline medication on immune-related adverse events occurring during combination immunotherapy: an exploratory study

HOSTETTLER M., 2019. 27, Université de Lausanne, Faculté de biologie et médecine, MICHIELIN O. (dir.).

[serval:BIB_481488956F55]

preview resource BIB_AD0E970E95CE.P001

CANCER IMMUNOTHERAPY WITH VEGFR-3 TARGETED CAR T-CELLS

KIRITSIS K., 2016. 32, Université de Lausanne, Faculté de biologie et médecine, COUKOS G. (dir.).

[URN][serval:BIB_AD0E970E95CE]

Phd thesis

Publications (12)

preview resource BIB_22651FF6D862.P002

Novel antibody-based therapeutic approaches for redirecting T cell effector functions towards tumors expressing CD248 (TEM1)

Fierle Julie Katrin, 2020/04/06., Université de Lausanne, Faculté de biologie et médecine, Coukos George (dir.).

[URN][serval:BIB_22651FF6D862]

preview resource BIB_7417869DA8E8.P002

Development of novel methods for high-throughput analyses of human tumor antigen-specific CD4 T cell responses

Rockinger Georg Alexander, 2020/02/28., Université de Lausanne, Faculté de biologie et médecine, Romero Pedro (dir.).

[URN][serval:BIB_7417869DA8E8]

An Integrated Immunopeptidomics and Proteogenomics Framework to Discover Non-Canonical Targets for Cancer Immunotherapy

CHONG Chloe, 2020., Université de Lausanne, Faculté de biologie et médecine, Coukos George (dir.).

[URN][serval:BIB_E6A1E69D2351]

Enforced PGC-1ɑ expression promotes CD8 T cell fitness, memory formation and anti-tumor immunity

DUMAUTHIOZ Nina, 2020., Université de Lausanne, Faculté de biologie et médecine, Romero Pedro (dir.).

[serval:BIB_2D4ABE6915B2]

preview resource BIB_5EBE536D2CB3.P003

Molecular and functional immune determinants associated with the optimal immunogenicity of Yellow Fever vaccination in humans

Bovay Amandine Xuan Kim, 2019/06/07., Université de Lausanne, Faculté de biologie et médecine, Speiser Daniel (dir.).

[URN][serval:BIB_5EBE536D2CB3]

Cytolytic CD4 T cells: Analysis of a novel T cell candidate for human tumor immunotherapy

Cachot Amélie, 2019., Université de Lausanne, Faculté de biologie et médecine, Romero Pedro (dir.).

[serval:BIB_F0A6BE95CE46]

Molecular mechanisms regulating TCR affinity-improved T cells against the NY-ESO-1 tumor antigen

ERDES Efe, 2019., Université de Lausanne, Faculté de biologie et médecine, Rufer Nathalie (dir.).

[serval:BIB_6F539C8E9170]

Identification and Isolation of Highly Functional Tumor-Specific CD8 T Cenis for Adoptive Cell Transfer Therapy

MAGNIN Morgane, 2019., Université de Lausanne, Faculté de biologie et médecine, HARARI Alexandre (dir.).

[URN][serval:BIB_E25A9568380B]

Molecular mechanisms of lymphatic vascular maintenance and repair

Saygili-Demir Cansaran, 2019., Université de Lausanne, Faculté de biologie et médecine, Petrova Tatiana (dir.).

[serval:BIB_A491C5859416]

preview resource BIB_08CEE3B79D75.P003

Molecular determinants governing CD8+ T cell mediated anti-tumor immunity

Martinez-Usatorre Amaia, 2018/04/27. 117, Université de Lausanne, Faculté de biologie et médecine, Romero Pedro (dir.).

[URN][serval:BIB_08CEE3B79D75]

preview resource BIB_786BC3B46C6D.P002

Harnessing iNKT and CD8 T cells for Immunotherapy of Cancer

Tschumi Benjamin Olivier, 2018/03/13. 117, Université de Lausanne, Faculté de biologie et médecine, Romero Pedro (dir.).

[URN][serval:BIB_786BC3B46C6D]

preview resource BIB_9F9512EEBA1F.P001

Characterization of local and systemic immune-modulation in melanoma patients

Bordy N., 2015. 204, Université de Lausanne, Faculté de biologie et médecine, Speiser D., Swartz M. (dir.).

[URN][serval:BIB_9F9512EEBA1F]

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