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Department of Oncology

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Publications | Masters and Phd thesis

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In Press | 2020 | ...

The human CD8 T stem cell-like memory phenotype appears in the acute phase in Yellow Fever virus vaccination

Marraco Silvia A. Fuertes, Bovay Amandine, Nassiri Sina, Maby-El Hajjami Hélène, Ouertatani-Sakouhi Hajer, Held Werner, Speiser Daniel E..

[DOI][serval:BIB_D644B7DF7CE4]

In Press

Early drop of circulating T cells negatively correlates with the protective immune response to Yellow Fever vaccination.

Bovay A., Speiser D.E., Fuertes Marraco S.A. Human vaccines & immunotherapeutics pp. 1-8. Peer-reviewed.

[DOI][Pmid][serval:BIB_CF63CEAB6BA5]

Lactate modulation of immune responses in inflammatory versus tumour microenvironments.

Certo M., Tsai C.H., Pucino V., Ho P.C., Mauro C. Nature reviews. Immunology. Peer-reviewed.

[DOI][Pmid][serval:BIB_EEC32C274BAF]

Structural dissimilarity from self drives neoepitope escape from immune tolerance.

Devlin J.R., Alonso J.A., Ayres C.M., Keller GLJ, Bobisse S., Vander Kooi C.W., Coukos G., Gfeller D., Harari A., Baker B.M. Nature chemical biology. Peer-reviewed.

[DOI][WoS][Pmid][serval:BIB_186F0AD1C570]

Enforced PGC-1α expression promotes CD8 T cell fitness, memory formation and antitumor immunity.

Dumauthioz N., Tschumi B., Wenes M., Marti B., Wang H., Franco F., Li W., Lopez-Mejia I.C., Fajas L., Ho P.C. et al. Cellular & molecular immunology. Peer-reviewed.

[DOI][Pmid][serval:BIB_D554C59D6F3C]

2020

Integrated proteogenomic deep sequencing and analytics accurately identify non-canonical peptides in tumor immunopeptidomes

Chong Chloe, Müller Markus, Pak HuiSong, Harnett Dermot, Huber Florian, Grun Delphine, Leleu Marion, Auger Aymeric, Arnaud Marion, Stevenson Brian J. et al., 2020/12. Nature Communications, 11 (1).

[DOI][Pmid][serval:BIB_03EA897A1141]

The hidden side of PD-L1.

Jaccard A., Ho P.C., 2020/09. Nature cell biology, 22 (9) pp. 1031-1032. Peer-reviewed.

[DOI][WoS][Pmid][serval:BIB_CDDD22AA09ED]

<sup>177</sup>Lu radiolabeling and preclinical theranostic study of 1C1m-Fc: an anti-TEM-1 scFv-Fc fusion protein in soft tissue sarcoma.

Delage J.A., Faivre-Chauvet A., Fierle J.K., Gnesin S., Schaefer N., Coukos G., Dunn S.M., Viertl D., Prior J.O., 2020/08/17. EJNMMI research, 10 (1) p. 98. Peer-reviewed.

[DOI][Pmid][serval:BIB_4E04534CDA56]

Adipocyte-conditioned medium induces resistance of breast cancer cells to lapatinib.

Geneste A., Duong M.N., Molina L., Conilh L., Beaumel S., Cleret A., Chettab K., Lachat M., Jordheim L.P., Matera E.L. et al., 2020/08/14. BMC pharmacology & toxicology, 21 (1) p. 61. Peer-reviewed.

[DOI][WoS][Pmid][serval:BIB_5A5A38569592]

Rapid tumor vaccine using Toll-like receptor-activated ovarian cancer ascites monocytes.

Adams S.F., Grimm A.J., Chiang C.L., Mookerjee A., Flies D., Jean S., McCann G.A., Michaux J., Pak H., Huber F. et al., 2020/08. Journal for immunotherapy of cancer, 8 (2). Peer-reviewed.

[DOI][Pmid][serval:BIB_7B7CF92C7BCB]

Preclinical Evaluation and Dosimetry of [<sup>111</sup>In]CHX-DTPA-scFv78-Fc Targeting Endosialin/Tumor Endothelial Marker 1 (TEM1).

Cicone F., Denoël T., Gnesin S., Riggi N., Irving M., Jakka G., Schaefer N., Viertl D., Coukos G., Prior J.O., 2020/08. Molecular imaging and biology, 22 (4) pp. 979-991. Peer-reviewed.

[DOI][WoS][Pmid][serval:BIB_813B48F40C5F]

Distinct and shared gene expression for human innate versus adaptive helper lymphoid cells.

Ercolano G., Wyss T., Salomé B., Romero P., Trabanelli S., Jandus C., 2020/08. Journal of leukocyte biology, 108 (2) pp. 723-737. Peer-reviewed.

[DOI][WoS][Pmid][serval:BIB_4DA23DC9CF93]

Dynamic changes in glioma macrophage populations after radiotherapy reveal CSF-1R inhibition as a strategy to overcome resistance.

Akkari L., Bowman R.L., Tessier J., Klemm F., Handgraaf S.M., de Groot M., Quail D.F., Tillard L., Gadiot J., Huse J.T. et al., 2020/07/15. Science Translational Medicine, 12 (552). Peer-reviewed.

[DOI][Pmid][serval:BIB_1B0920FD434E]

A mouse SWATH-mass spectrometry reference spectral library enables deconvolution of species-specific proteomic alterations in human tumour xenografts.

Krasny L., Bland P., Burns J., Lima N.C., Harrison P.T., Pacini L., Elms M.L., Ning J., Martinez V.G., Yu Y.R. et al., 2020/07/14. Disease models & mechanisms, 13 (7). Peer-reviewed.

[DOI][Pmid][serval:BIB_AECF31D38959]

Pharmacological disruption of the Notch transcription factor complex.

Lehal R., Zaric J., Vigolo M., Urech C., Frismantas V., Zangger N., Cao L., Berger A., Chicote I., Loubéry S. et al., 2020/07/14. Proceedings of the National Academy of Sciences of the United States of America, 117 (28) pp. 16292-16301. Peer-reviewed.

[DOI][WoS][Pmid][serval:BIB_53A51DDF8D0E]

CD40 agonist restores the antitumor efficacy of anti-PD1 therapy in muscle-invasive bladder cancer in an IFN I/II-mediated manner

Leblond Marine M, Tillé Laure, Nassiri Sina, Gilfillan Connie B, Imbratta Claire, Schmittnaegel Martina, Ries Carola H., Speiser Daniel E., Verdeil Grégory, 2020/07/13. Cancer Immunology Research pp. canimm.0826.2019.

[DOI][serval:BIB_03172EE2E8EA]

Biological functions of lymphatic vessels.

Petrova T.V., Koh G.Y., 2020/07/10. Science, 369 (6500). Peer-reviewed.

[DOI][Pmid][serval:BIB_0975AC40A1DE]

Multielemental Analysis of Low-Volume Samples Reveals Cancer-Specific Profile in Serum and Sorted Immune Cells

Konz Tobias, Monnard Caroline, Restrepo Marcela Rincon, Laval Julie, Sizzano Federico, Girotra Mukul, Dammone Gabriele, Palini Alessio, Coukos George, Rezzi Serge et al., 2020/07/07. Analytical Chemistry, 92 (13) pp. 8750-8758.

[DOI][Pmid][serval:BIB_3A58DA889942]

Identification of a superagonist variant of the immunodominant Yellow fever virus epitope NS4b <sub>214-222</sub> by combinatorial peptide library screening.

Bovay A., Zoete V., Rizkallah P.J., Beck K., Delbreil P., Speiser D.E., Cole D.K., Fuertes Marraco S.A., 2020/07/06. Molecular immunology, 125 pp. 43-50. Peer-reviewed.

[DOI][Pmid][serval:BIB_46FDF2862443]

Interrogation of the Microenvironmental Landscape in Brain Tumors Reveals Disease-Specific Alterations of Immune Cells

Klemm F., Maas R.R., Bowman R.L., Kornete M., Soukup K., Nassiri S., Brouland J.P., Iacobuzio-Donahue C.A., Brennan C., Tabar V. et al., 2020/06/25. Cell, 181 (7) pp. 1643-1660.e17. Peer-reviewed.

[DOI][Pmid][serval:BIB_B25384BE18E8]

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Masters thesis

Publications (1)

preview resource BIB_AD0E970E95CE.P001

CANCER IMMUNOTHERAPY WITH VEGFR-3 TARGETED CAR T-CELLS

KIRITSIS K., 2016. 32, Université de Lausanne, Faculté de biologie et médecine, COUKOS G. (dir.).

[URN][serval:BIB_AD0E970E95CE]

Phd thesis

Publications (12)

preview resource BIB_22651FF6D862.P002

Novel antibody-based therapeutic approaches for redirecting T cell effector functions towards tumors expressing CD248 (TEM1)

Fierle Julie Katrin, 2020/04/06., Université de Lausanne, Faculté de biologie et médecine, Coukos George (dir.).

[URN][serval:BIB_22651FF6D862]

preview resource BIB_7417869DA8E8.P002

Development of novel methods for high-throughput analyses of human tumor antigen-specific CD4 T cell responses

Rockinger Georg Alexander, 2020/02/28., Université de Lausanne, Faculté de biologie et médecine, Romero Pedro (dir.).

[URN][serval:BIB_7417869DA8E8]

An Integrated Immunopeptidomics and Proteogenomics Framework to Discover Non-Canonical Targets for Cancer Immunotherapy

CHONG Chloe, 2020., Université de Lausanne, Faculté de biologie et médecine, Coukos George (dir.).

[URN][serval:BIB_E6A1E69D2351]

Enforced PGC-1ɑ expression promotes CD8 T cell fitness, memory formation and anti-tumor immunity

DUMAUTHIOZ Nina, 2020., Université de Lausanne, Faculté de biologie et médecine, Romero Pedro (dir.).

[serval:BIB_2D4ABE6915B2]

preview resource BIB_5EBE536D2CB3.P003

Molecular and functional immune determinants associated with the optimal immunogenicity of Yellow Fever vaccination in humans

Bovay Amandine Xuan Kim, 2019/06/07., Université de Lausanne, Faculté de biologie et médecine, Speiser Daniel (dir.).

[URN][serval:BIB_5EBE536D2CB3]

Cytolytic CD4 T cells: Analysis of a novel T cell candidate for human tumor immunotherapy

Cachot Amélie, 2019., Université de Lausanne, Faculté de biologie et médecine, Romero Pedro (dir.).

[serval:BIB_F0A6BE95CE46]

Molecular mechanisms regulating TCR affinity-improved T cells against the NY-ESO-1 tumor antigen

ERDES Efe, 2019., Université de Lausanne, Faculté de biologie et médecine, Rufer Nathalie (dir.).

[serval:BIB_6F539C8E9170]

Identification and Isolation of Highly Functional Tumor-Specific CD8 T Cenis for Adoptive Cell Transfer Therapy

MAGNIN Morgane, 2019., Université de Lausanne, Faculté de biologie et médecine, HARARI Alexandre (dir.).

[URN][serval:BIB_E25A9568380B]

Molecular mechanisms of lymphatic vascular maintenance and repair

Saygili-Demir Cansaran, 2019., Université de Lausanne, Faculté de biologie et médecine, Petrova Tatiana (dir.).

[serval:BIB_A491C5859416]

preview resource BIB_08CEE3B79D75.P003

Molecular determinants governing CD8+ T cell mediated anti-tumor immunity

Martinez-Usatorre Amaia, 2018/04/27. 117, Université de Lausanne, Faculté de biologie et médecine, Romero Pedro (dir.).

[URN][serval:BIB_08CEE3B79D75]

preview resource BIB_786BC3B46C6D.P002

Harnessing iNKT and CD8 T cells for Immunotherapy of Cancer

Tschumi Benjamin Olivier, 2018/03/13. 117, Université de Lausanne, Faculté de biologie et médecine, Romero Pedro (dir.).

[URN][serval:BIB_786BC3B46C6D]

preview resource BIB_9F9512EEBA1F.P001

Characterization of local and systemic immune-modulation in melanoma patients

Bordy N., 2015. 204, Université de Lausanne, Faculté de biologie et médecine, Speiser D., Swartz M. (dir.).

[URN][serval:BIB_9F9512EEBA1F]

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