Projects


 

The research focus of our group is on the study of sexual dimorphism in metabolism, in health, ageing and age-related neurodegenerative diseases.

To investigate sex and age-related variation of energy and of lipid metabolism we apply quantitative mass spectrometry-based metabolomic and lipidomic approaches to clinical, human population studies.

In parallel, we are actively developing new analytical methodologies to improve metabolite and lipid quantification, and metabolomic data interpretation in the context of metabolic networks.

 

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Read about gender data gap

"We continue to rely on data from studies done on men as if they apply to women"

The Guardian (C. Criado-Perez "Invisible Women: Exposing Data Bias in a World Designed for Men)

 

Lipid Metabolism in the Context of Age-related Sexual Dimorphism

Project In collaboration with
Metabolic phenotyping of adult Caucasian population of Lausanne (CoLaus): exploring age-related sex differences in plasma lipidome (including steroidome) CoLaus clinical consortium CHUV (prof. Peter Vollenweider, prof. Pedro-Manuel Marques-Vidal)

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Aging Brain: Is Neurodegeneration a Sex-associated Metabolic Disorder?

Project In collaboration with
Alzheimer's disease - a brain energy metabolism disorder: Experimental & clinical population study Prof. Julius Popp, MD, CHUV
What can 3xTg-AD mouse model tell us about sex-associated predisposition to Alzheimer's disease? Dr. Jean-Yves Chatton PD, UNIL

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Metabolomic Data Processing & Interpretation

Project Responsible PI
Contribution to continuous update of XCMS - the most widely used open-access tool for data processing in metabolomics community, and METLIN - the most comprehensive standard metabolite database and spectral library Prof. Gary Siuzdak
Scripps, CA, US
Follow us:  
Quartier UNIL-CHUV - Rue du Bugnon 19 - CH-1005 Lausanne
Switzerland
Tel. +41 21 692 50 98