portrait-DuPasquier.jpg                            Pot-Kreis.jpg (POT CAROLINE DNC)

Prof Renaud Du Pasquier                     Prof Caroline Pot
Full Professor                                           Assoc. Prof.

Laboratory activity
Multiple sclerosis (MS) is an auto-inflammatory disease of the central nervous system, where all components of the immune system, innate and adaptive, are involved. In addition to genetic factors, environmental ones play a crucial role in triggering this complex disease. In the Laboratories of neuroimmunology, we examine how environmental factors, among which Epstein-Barr virus, gut microbiome or cholesterol metabolites support autoreactivity of B and T cells. To tackle our hypothesis, we use different approaches, including animal models, namely the experimental autoimmune encephalomyelitis, human samples analysis (blood, cerebrospinal fluid, urine, soon stools) of MS patients and a human in vitro model of MS brain, using induced pluripotent stem cells (iPCS).

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Bâtiment Champ de l'Air - Rue du Bugnon 21 - CH-1011 Lausanne
Tel. +41 79 556 97 74
Centre Hospitalier Universitaire Vaudois (CHUV)