Cortic. excitability and arousal Dis.

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Philippe Ryvlin          Andrea Rossetti           Jan Novy                      Carolina Ciumas

Professor                    Assoc. Professor           adjunct Professor        Fellow/Postdoctoral researcher

Head of Department                                         Senior Lecturer
Head of Laboratory


Laboratory activity
Our laboratory’s activities are focusing on clinical research in patients with epilepsy or disorders of consciousness of various origin, including status-epilepticus and post-anoxic coma. In epilepsy, six main research objectives are being developed:

  • Pathophysiology and prevention of Sudden Unexpected Death in Epilepsy Patients (SUDEP).
  • Seizure detection in ambulatory patients using mobile health technology.
  • Optimisation of pre-surgical evaluation and epilepsy surgery.
  • Point-of-care testing of antiepileptic drugs plasma dosage.
  • Pharmacogenomic/biomarkers of the disease.
  • Epidemiology and management of status-epilepticus.

In disorders of consciousness, our current research primarily focuses on outcome prognostication of acute coma, particularly after cardiac arrest. The methods used in our laboratory include clinical neurophysiology (scalp-EEG, intra-cerebral EEG, evoked potentials), neuroimaging (MRI, functional MRI, PET), biology (dosage of AEDs, genomic), epidemiology and randomized controled trials.

Bâtiment Champ de l'Air - Rue du Bugnon 21 - CH-1011 Lausanne
Tel. +41 21 314 96 57
Centre Hospitalier Universitaire Vaudois (CHUV)