Ann-Marie De Lange
SNSF Ambizione Fellow, Laboratory for Research in Neuroimaging - LREN
Affiliation: Service of neurology (NLG), Department of Psychiatry, University of Oxford, UK, Department of Psychology, University of Oslo, Norway
Keywords: Brain health and ageing, Women’s health, Mental health, Neuroimaging, Big-data analysis, Machine learning
> Menopause and brain ageing
> Cardiometabolic health and lifestyle
> Brain plasticity in pregnancy
> Mental health and depression
> Sex-hormones and neuroendocrinology
Description of the laboratory's activity
Women are at greater risk of developing Alzheimer’s disease relative to men, and have higher prevalence of autoimmune diseases and depression. As women's health is historically understudied, little is known about mechanisms underlying epidemiological sex differences in disease, and how factors such as sex-hormones influence brain health across the female lifespan.
FemiLab aims to increase the understanding of transitional life phases including puberty, pregnancy, and menopause, and how biological and psychosocial factors related to these events influence brain health. To investigate this, we analyse brain imaging, clinical, genetic, biological, and psychosocial data from large population-based studies.