Prof Stephanie Clarke
Head of the Neuropsychology and Neurorehabilitation Service
Head of the Laboratory of Cognitive Science
Affiliation: Service of neuropsychology and neurorehabilitation (NPR)
Keywords: Cognitive functions, Neural plasticity, Recovery from brain lesions, Neuropsychology, Auditory cognition, Cerebral cortex
Stephanie Clarke, Sonia Crottaz-Herbette and Stefano Carda investigate cognitive and motor functions in normal subjects and in brain-damaged patients, with particular interest in the organisation and plasticity of the human auditory and motor cortices.
The laboratory pursues three lines of research to investigate plasticity, which underlies the effectiveness of brief therapeutic interventions in cognitive rehabilitation.
> “Sound objects in space and time”, SNSF grant 159708 to S. Clarke (2015-19; CHF834’000) investigates combined representations of sound meaning, location and temporal features, using psychophysical approaches, fMRI and EEG. Understanding how semantic representations are linked to the spatial or temporal characteristics of an object will provide insight into multisensory and object-related representations of space.
> Dr. Sonia Crottaz-Herbette investigates the impacts of brief therapeutic interventions on recovery of cognitive functions using fMRI. After her topical studies on the effect of prismatic adaptation in neglect, she addresses the mechanisms of working memory recovery.
> Dr. Stefano Carda investigates the effects of electrically-assisted movement therapy on motor control of patients with severe upper limb paralysis. He is further involved in a project using fMRI to determine neural substrates of upper limb recovery using this treatment. A better understanding of the neural mechanisms underlying these effects is likely to focus indications for specific rehabilitation programs and help to design new therapies.