Ho Lab members

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Francesca ALFEI
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Postdoctoral researcher
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Research interest 

Understanding the crosstalk between dendritic cells and T-cells in tailoring CD8+ T cell anti-tumor responses.

Background 

I studied Medical Biotechnology at the University of Rome “Sapienza” and obtained my PhD in Life Science at the Technical University of Munich.hnology at the University of Rome “Sapienza” and obtained my PhD in Life Science at the Technical University of Munich. 

Alessio BEVILACQUA
Ho Lab Alessio Bevilacqua-crop201x194.jpeg PhD student
CONTACT ME

Research interest

Metabolic reprogramming in memory and exhausted T cells.

Background

Master’s in Biomedical Sciences from the Université Catholique de Louvain.

Yu-Ming CHUANG
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PhD student
CONTACT ME

Research interest 

My focus is on how metabolic regulation controls cancer metastasis and T cell exhaustion.

Background 

I studied epigenomic regulation and bioinformatic analysis in cancer during my master’s at the Institute of Biomedical Sciences, National Chung Cheng University, Taiwan.

Giusy DI CONZA
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Postdoctoral researcher
CONTACT ME

Research interest 

Cancer biology has been the focus of my research during my doctoral and postdoctoral training. In the Ho Lab, by exploring a metabolic angle of intratumoral interactions, I am studying how cancer cells sustain their growth by shaping macrophage towards an immunosuppressive phenotype through release of specific lipids.

Background 

  • Master degree in ‘Medical Biotechnology’, University ‘Sapienza’ of Rome.

  • PhD in Experimental Endocrinology and Metabolic Disease, University of Messina/CNR- Ist. of Cell Biology, Rome.

  • Postdoc (FWO-Marie Curie Fellow) at the VIB, KU Leuven.

Fabien FRANCO
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PhD student
CONTACT ME

Research interest 

I am interested in understanding the role of metabolism during CD8 T cell differentiation. I specifically focus on determining the role of mitochondria recycling during formation of memory T cells. 

Background 

I studied biology at the University of Lausanne. After the bachelor’s degree, I did my Master's in Medical Biology, still in Lausanne.

Pei-Chun HSUEH
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Postdoctoral researcher
CONTACT ME

Research interest 

My expertise is in working with the proteomics and metabolomics analysis. Aging leads to a progressive functional decline in T cell anti-tumor responses, new information about this process will be valuable to the restoring and/or sustaining of T cell functions. My interest is to elucidate the mechanism in T cell aging and our goal unleash anti-tumor immunity by modulating the T cell metabolism.

Background 

I studied at Chang Gung University, Taiwan for my BSc through to my PhD.

Kung-Chi KAO
Ho Lab Kung-Chi Kao-crop384x400.jpg PhD student
CONTACT ME

Research interest 

Metabolic adapatation of regulatory T cells in tumors.

Background

  • University of Lausanne, Department of Oncology: PhD student / 2020-Present

  • University of Zurich, Institute of Experimental Immunology: PhD student /2019 - 2020

  • National Taiwan University, Graduate Institute of Immunology: Research assistant / 2014 - 2019

  • National Taiwan University, Graduate Institute of Immunology: MSc/ 2012 - 2014

  • National Chung Hsing University, Bachelor Program of Biotechnology: BSc. / 2008 - 2012

Xiaoyun LI
Ho Lab Xiaoyun Li-crop367x371.jpeg PhD student
CONTACT ME

Research interest 

I am working on delineating how the metabolic crosstalk between cancer-associated fibroblasts and cancer cell instructing the polarization of macrophages in tumors.

Background 

I obtained my bachelor’s degree and master’s in Soochow University, China, joining the University of Lausanne for my PhD.

Zhiyu LI
Ho Lab Zhiyu Li-crop675x634.JPG Visiting scientist
CONTACT ME

Research interest 

Metabolic checkpoint in dendritic cell behaviour. 

Background 

Clinical study in breast cancer; tumor metabolism and microenvironment. I graduated from Wuhan University, majoring breast and thyroid surgery.

Sophie Hedlund MOLLER
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Postdoctoral researcher
CONTACT ME

Research interest 

I am currently interested in understanding the impact of the gut microbiota on the anti-cancer immune response, focusing on the role of myeloid cells in particular.

Background 

I have a Master’s degree in Molecular Biomedicine and during my PhD I investigated the metabolic regulation of immune stimulatory NKG2D ligands in the lab of Søren Skov at the University of Copenhagen.

Pia NEUBERT
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CONTACT ME

Research interest 

T cell exhaustion and mitochondrial biology in T cells in chronic viral infection. 

Background

I have an MSc in Medical Biology from the University Lausanne with a major in Immunology and Cancer.

Limei WANG
Ho Lab Limei Wang-crop471x447.JPG Postdoctoral researcher
CONTACT ME

Research interest 

My major topic is the metabolic programming in dendritic cells and T cells mediates immune responses and homeostasis.

Background 

I received my PhD in 2018 from the University of Bern’s Department of BioMedical research, focusing on identifying mesenchymal and epithelial progenitor cell subtypes, tumor microenvironment and uncovering the molecular underpinnings of T cell exhaustion in human cancer. I worked at Harvard Medical School as a postdoctoral fellow for one year before joining the Ho Lab in September 2020.

Yi-Ru YU
Ho Lab Yi-Ru Yu-crop333x355.jpg Postdoctoral researcher
CONTACT ME

Research interest 

My current interest is to dissect the unidentified metabolic crosstalk between T cells and malignant cells in the tumor microenvironment and provide pillows for the potential therapeutic applications.

Background 

During my PhD studies, I focused on the role of ovarian cancer gene 1 (Ovca1) in congenital disease and tumorigenesis as a mouse geneticist in National Yang-Ming University in Taiwan. Currently, I’m working on the role of dysfunctional mitochondria in T cell exhaustion in the tumor microenvironment in UNIL.

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CONTACT

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Ping-Chih HO
Associate Professor
Ludwig associate member
Laboratory P-C. Ho

Department of oncology UNIL CHUV
Ludwig Institute for Cancer Research Lausanne

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Phone +41 21 692 59 47
E-mail

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The Ho Lab is based at:

Centre de Laboratoire Epalinges (CLE)
Ch. des Boveresses 155
CH-1066 Epalinges
Switzerland

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Ch. des Boveresses 155 - CH-1066 Epalinges
Switzerland
Tel. +41 21 692 59 92
Fax +41 21 692 59 95
Ludwig Cancer Research Université de Lausanne Centre Hospitalier Universitaire Vaudois (CHUV)