After a bachelor in life sciences from the University of Montpellier (France), I obtained a Master in Evolutionary Biology from the University of Montpellier and the University of Groningen (Netherlands) as part of the Master Erasmus Mundus in Evolutionary Biology (MEME). I then obtained a Master in Bioinformatics from the University of Rennes (France). Following that, I worked as a bioinformatician in the Laboratoire de Physiologie et Genomique des Poissons at INRA in Rennes (France), where I developed tools to analyze population genomic datasets to study sex-determination in fishes. I am now pursuing a PhD in the Waterhouse group on the relationship between sequence conservation and function in Mosquitoes.
I am generally interested in all aspects of genome evolution; I want to understand as much as possible about how genomes shape and influence the diversity of life. In practice, this means studying the relationships between genes and phenotypes, but also the evolutionary history of these genes. It also involves better understanding the roles and evolutionary forces acting on non-coding regions of the genome; an outcome of my PhD project will involve facilitating the identification and characterization of non-coding functional elements in genomes.
On the technical side, I enjoy implementing tools and pipelines that can be used by the genomic community. I am also a proponent of open and reproducible science, and I am implementing these ideas in my PhD work by using and promoting tools such as Snakemake and Bioconda.
2018 - present
PhD student with Robert Waterhouse at UNIL, investigating the relationship between sequence conservation and function in mosquitoes using multispecies whole genome alignments.
2017 - 2018
Bioinformatician at INRA LPGP (Rennes, France) working with Dr. Yann Guiguen on developing sequencing data analysis pipelines to investigate sex determination in fishes.
2015 - 2016
Master 2 in Bioinformatics and Genomics , Université Rennes 1, Rennes, France
2012 - 2014
Erasmus Mundus Master in Evolutionary Biology, Uppsala Universitet, Université Montpellier 2, & Rijksuniversiteit Groningen
2011 - 2012
Bachelor degree in Biology and Earth Sciences, Université Montpellier 2, Montpellier, France
2009 - 2011
CPGE Biology, Physics, Chemistry and Geology (BCPST), Lycée Joffre, Montpellier, France
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Exploring new genomic territories with emerging model insects.
2022/06. , 51 p. 100902. Peer-reviewed., ,
Genome biology of the darkedged splitfin, Girardinichthys multiradiatus, and the evolution of sex chromosomes and placentation.
2022/03. , 32 (3) pp. 583-594. Peer-reviewed., , , , , , , , , et al.,
Assessing species coverage and assembly quality of rapidly accumulating sequenced genomes.
2022/02/25. , 11 pp. giac006. Peer-reviewed., ,
Functional Constraints on Insect Immune System Components Govern Their Evolutionary Trajectories.
2022/01/07. , 39 (1) pp. msab352. Peer-reviewed., , , , ,
A supernumerary "B-sex" chromosome drives male sex determination in the Pachón cavefish, Astyanax mexicanus.
2021/11/08. , 31 (21) pp. 4800-4809.e9. Peer-reviewed., , , , , , , , , et al.,
A duplicated copy of id2b is an unusual sex-determining candidate gene on the Y chromosome of arapaima (Arapaima gigas).
2021/11/03. , 11 (1) p. 21544. Peer-reviewed., , , , , , , , , et al.,
The bowfin genome illuminates the developmental evolution of ray-finned fishes.
2021/09. , 53 (9) pp. 1373-1384. Peer-reviewed., , , , , , , , , et al.,
RADSex: A computational workflow to study sex determination using restriction site-associated DNA sequencing data.
2021/07. , 21 (5) pp. 1715-1731. Peer-reviewed., , , , , , , , , et al.,
The rise and fall of the ancient northern pike master sex determining gene
2021/01. , 10 pp. e62858., , , , , , , , , et al.,
Evolutionary superscaffolding and chromosome anchoring to improve Anopheles genome assemblies
2020/12. , 18 (1). Peer-reviewed., , , , , , , , , et al.,
Sex chromosome and sex locus characterization in goldfish, Carassius auratus (Linnaeus, 1758).
2020/08/11. , 21 (1) p. 552. Peer-reviewed., , , , , , , , , et al.,
The sterlet sturgeon genome sequence and the mechanisms of segmental rediploidization.
2020/06. , 4 (6) pp. 841-852. Peer-reviewed., , , , , , , , , et al.,
Characterization of a Y-specific duplication/insertion of the anti-Mullerian hormone type II receptor gene based on a chromosome-scale genome assembly of yellow perch, Perca flavescens.
2020/03. , 20 (2) pp. 531-543. Peer-reviewed., , , , , , , , , et al.,
Independent Origin of XY and ZW Sex Determination Mechanisms in Mosquitofish Sister Species
2019/11/08. pp. genetics.302698.2019., , , , , , , , , et al.,
Identification of the master sex determining gene in Northern pike (Esox lucius) reveals restricted sex chromosome differentiation.
2019/08. , 15 (8) pp. e1008013. Peer-reviewed., , , , , , , , , et al.,
The genome of the arapaima (Arapaima gigas) provides insights into gigantism, fast growth and chromosomal sex determination system
2019. , 9 (1) p. 5293., , , , , , , , , ,
Evolutionary superscaffolding and chromosome anchoring to improve Anopheles genome assemblies.
2019. ., , , , , , , , , et al.,
The evolution of mutual mate choice under direct benefits
2016. , 188 (5) pp. 521-538., , , , ,
Social learning and the replication process: an experimental investigation
2015. , 282 (1808) p. 20150719., , , ,